Gankyrin has an antioxidative role through the feedback regulation of Nrf2 in hepatocellular carcinoma

Journal of Experimental Medicine

Volumn 213, Issue 5, 2016, Pages 859-875

  Yang, Chun ^a,b   Tan, Ye xiong ^a,b   Yang, Guang zhen ^a   Zhang, Jian ^a,b   Pan, Yu fei ^a,b   Liu, Chen ^a,b   Fu, Jing ^a,b   Chen, Yao ^a,b   Ding, Zhi wen ^a,b   Dong, Li wei ^a,b   Wang, Hong yang ^a,b,c  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b Liver Cancer Institute   (China)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

GANKYRIN; KELCH LIKE ECH ASSOCIATED PROTEIN 1; ONCOPROTEIN; PROTEASOME; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; KEAP1 PROTEIN, HUMAN; NFE2L2 PROTEIN, HUMAN; PSMD10 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CANCER PROGNOSIS; CELL DEATH; DISEASE FREE SURVIVAL; FEEDBACK SYSTEM; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; MOUSE; NONHUMAN; OVERALL SURVIVAL; OXIDATIVE STRESS; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; DNA RESPONSIVE ELEMENT; GENETICS; IMMUNOLOGY; LIVER TUMOR; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; HUMANS; KELCH-LIKE ECH-ASSOCIATED PROTEIN 1; LIVER NEOPLASMS; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOLYSIS; PROTO-ONCOGENE PROTEINS; REACTIVE OXYGEN SPECIES; RESPONSE ELEMENTS; SIGNAL TRANSDUCTION;

EID: 84969244603     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20151208     Document Type: Article

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