Rotenone down-regulates HSPA8/hsc70 chaperone protein in vitro: A new possible toxic mechanism contributing to Parkinson's disease

NeuroToxicology

Volumn 54, Issue , 2016, Pages 161-169

  Sala, Gessica ^a   Marinig, Daniele ^a   Riva, Chiara ^a   Arosio, Alessandro ^a   Stefanoni, Giovanni ^a,b   Brighina, Laura ^a,b   Formenti, Matteo ^a   Alberghina, Lilia ^a   Colangelo, Anna Maria ^a   Ferrarese, Carlo ^a,b  

^a UNIVERSITY OF MILANO BICOCCA   (Italy)

^b SAN GERARDO HOSPITAL   (Italy)

Author keywords

Autophagy; Heat shock cognate protein 70; Parkinson's disease; Rotenone

Indexed keywords

ALPHA SYNUCLEIN; HEAT SHOCK COGNATE PROTEIN 70; HYDROGEN PEROXIDE; MESSENGER RNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); ROTENONE; HSPA8 PROTEIN, MOUSE; INSECTICIDE; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; AUTOPHAGY; BIOACCUMULATION; CELL VIABILITY; CHAPERONE MEDIATED AUTOPHAGY; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOTOXICITY; DISEASE ASSOCIATION; DISEASE MODEL; DOWN REGULATION; GENE EXPRESSION REGULATION; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; MACROAUTOPHAGY; MOLECULAR DYNAMICS; MOUSE; NEUROBLASTOMA CELL LINE; NEUROMODULATION; NEUROPATHOLOGY; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; SH SY5Y CELL LINE; UPREGULATION; ANIMAL; BRAIN CORTEX; C57BL MOUSE; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; GENETIC TRANSFECTION; GENETICS; METABOLISM; NERVE CELL; NEUROBLASTOMA; NEWBORN; PATHOLOGY; TIME FACTOR; TUMOR CELL LINE;

ALPHA-SYNUCLEIN; ANIMALS; ANIMALS, NEWBORN; CELL LINE, TUMOR; CELLS, CULTURED; CEREBRAL CORTEX; GENE EXPRESSION REGULATION; HSC70 HEAT-SHOCK PROTEINS; HUMANS; HYDROGEN PEROXIDE; INSECTICIDES; MICE; MICE, INBRED C57BL; NEUROBLASTOMA; NEURONS; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; ROTENONE; TIME FACTORS; TRANSFECTION;

EID: 84966430218     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2016.04.018     Document Type: Article

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