Rotenone inhibits autophagic flux prior to inducing cell death

ACS Chemical Neuroscience

Volumn 3, Issue 12, 2012, Pages 1063-1072

  Mader, Burton J ^a,b   Pivtoraiko, Violetta N ^a,c   Flippo, Hilary M ^a   Klocke, Barbara J ^c   Roth, Kevin A ^c   Mangieri, Leandra R ^a   Shacka, John J ^a,b  

^a University of Alabama at Birmingham   (United States)

^b BIRMINGHAM VA MEDICAL CENTER   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

autophagy; cell death; lysosome; Parkinson's disease; Rotenone; SH SY5Y

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALPHA SYNUCLEIN; CASPASE 3; MICROTUBULE ASSOCIATED PROTEIN; MICROTUBULE ASSOCIATED PROTEIN LIGHT CHAIN 3 II; PROTEIN P62; ROTENONE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; AUTOPHAGY; BIODEGRADATION; CANCER CELL CULTURE; CELL DEATH; CELL LEVEL; CELL VACUOLE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; HUMAN; HUMAN CELL; LYSOSOME; LYSOSOME MEMBRANE; PH; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

AUTOPHAGY; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; CELL DEATH; CELL LINE, TUMOR; HUMANS; LYSOSOMAL-ASSOCIATED MEMBRANE PROTEIN 1; LYSOSOMES; NEURONS; ROTENONE; UNCOUPLING AGENTS; VACUOLES;

EID: 84871266643     PISSN: None     EISSN: 19487193     Source Type: Journal    
DOI: 10.1021/cn300145z     Document Type: Article

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