Long-term heat shock proteins (HSPs) induction by carbenoxolone improves hallmark features of Parkinson's disease in a rotenone-based model

Neuropharmacology

Volumn 79, Issue , 2014, Pages 190-200

  Thakur, Poonam ^a   Nehru, Bimla ^a  

^a PANJAB UNIVERSITY   (India)

Author keywords

Synuclein; Oxidative stress; Protein aggregation; Protein carbonylation; Ubiquitin proteasome system

Indexed keywords

ALPHA SYNUCLEIN; CARBENOXOLONE; DOPAMINE; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 27; HEAT SHOCK PROTEIN 40; HEAT SHOCK PROTEIN 70; HEAT SHOCK TRANSCRIPTION FACTOR 1; PROTEASOME; TYROSINE 3 MONOOXYGENASE; UBIQUITIN PROTEASOME; UNCLASSIFIED DRUG; ANTIPARKINSON AGENT; DNA BINDING PROTEIN; HEAT SHOCK TRANSCRIPTION FACTOR; ROTENONE; TRANSCRIPTION FACTOR; UBIQUITIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN REGION; CLINICAL FEATURE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; ENZYME ACTIVITY; MALE; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CARBONYLATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; TREATMENT DURATION; TREATMENT OUTCOME; UPREGULATION; ANIMAL; DRUG EFFECTS; MESENCEPHALON; METABOLISM; MOTOR ACTIVITY; PARKINSONIAN DISORDERS; PATHOPHYSIOLOGY; PHYSIOLOGY; RANDOMIZATION; SPRAGUE DAWLEY RAT;

ALPHA-SYNUCLEIN; ANIMALS; ANTIPARKINSON AGENTS; APOPTOSIS; CARBENOXOLONE; DNA-BINDING PROTEINS; DOPAMINE; HEAT-SHOCK PROTEINS; MALE; MESENCEPHALON; MOTOR ACTIVITY; OXIDATIVE STRESS; PARKINSONIAN DISORDERS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; ROTENONE; TRANSCRIPTION FACTORS; TYROSINE 3-MONOOXYGENASE; UBIQUITIN;

EID: 84890500035     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2013.11.016     Document Type: Article

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