Subcutaneous administration of liraglutide ameliorates learning and memory impairment by modulating tau hyperphosphorylation via the glycogen synthase kinase-3β pathway in an amyloid β protein induced alzheimer disease mouse model

European Journal of Pharmacology

Volumn 783, Issue , 2016, Pages 23-32

  Qi, Liqin ^a   Ke, Linfang ^a   Liu, Xiaohong ^a   Liao, Lianming ^a   Ke, Sujie ^a   Liu, Xiaoying ^a   Wang, Yanping ^a   Lin, Xiaowei ^a   Zhou, Yu ^a   Wu, Lijuan ^a   Chen, Zhou ^a   Liu, Libin ^a  

^a FUJIAN MEDICAL UNIVERSITY   (China)

Author keywords

Alzheimer disease; Amyloid beta protein; GLP 1; GSK 3 ; Tau protein

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; GLUCAGON; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; GLUCOSE; GLYCOGEN SYNTHASE KINASE 3BETA; INSULIN; LIRAGLUTIDE; PROTEIN KINASE B; TAU PROTEIN; AMYLOID BETA-PROTEIN (1-42); PEPTIDE FRAGMENT;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ULTRASTRUCTURE; CONTROLLED STUDY; DRUG MECHANISM; GLUCAGON BLOOD LEVEL; GLUCOSE BLOOD LEVEL; HIPPOCAMPAL CA1 REGION; INSULIN BLOOD LEVEL; LEARNING DISORDER; MALE; MEMORY DISORDER; MORRIS WATER MAZE TEST; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PYRAMIDAL NERVE CELL; SIGNAL TRANSDUCTION; SPATIAL LEARNING; SPATIAL MEMORY; SYNAPSE; Y-MAZE TEST; ANIMAL; C57BL MOUSE; DISEASE MODEL; DRUG EFFECTS; GENE EXPRESSION REGULATION; HIPPOCAMPUS; MAZE TEST; MEMORY; METABOLISM; NERVE CELL; PATHOLOGY; PATHOPHYSIOLOGY; PHOSPHORYLATION; ULTRASTRUCTURE;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; GLUCAGON-LIKE PEPTIDE-1 RECEPTOR; GLYCOGEN SYNTHASE KINASE 3 BETA; HIPPOCAMPUS; LIRAGLUTIDE; MALE; MAZE LEARNING; MEMORY; MICE; MICE, INBRED C57BL; NEURONS; PEPTIDE FRAGMENTS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SPATIAL LEARNING; SYNAPSES; TAU PROTEINS;

EID: 84965162519     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2016.04.052     Document Type: Article

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