메뉴 건너뛰기




Volumn 8, Issue 2, 2016, Pages 120-128

Adiponectin: A versatile player of innate immunity

Author keywords

adiponectin; innate immunity; innate like lymphocyte; macrophage

Indexed keywords

ADIPONECTIN;

EID: 84965067272     PISSN: 16742788     EISSN: 17594685     Source Type: Journal    
DOI: 10.1093/jmcb/mjw012     Document Type: Review
Times cited : (176)

References (106)
  • 1
    • 34247556686 scopus 로고    scopus 로고
    • Adipose tissue as an endocrine organ
    • Ahima, R.S. (2006). Adipose tissue as an endocrine organ. Obesity (Silver Spring) 14(Suppl 5), 242S-249S.
    • (2006) Obesity (Silver Spring) , vol.14 , pp. 242S-249S
    • Ahima, R.S.1
  • 2
    • 17844396206 scopus 로고    scopus 로고
    • Adiponectin inhibits LPS-induced NF-kB activation and IL-6 production and increases PPARg2 expression in adipocytes
    • Ajuwon, K.M., and Spurlock, M.E. (2005). Adiponectin inhibits LPS-induced NF-kB activation and IL-6 production and increases PPARg2 expression in adipocytes. Am. J. Physiol. Regul. Integr. Comp. Physiol. 288, R1220-R1225.
    • (2005) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.288 , pp. R1220-R1225
    • Ajuwon, K.M.1    Spurlock, M.E.2
  • 3
    • 0037911660 scopus 로고    scopus 로고
    • Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity
    • Akbari, O., Stock, P., Meyer, E., et al. (2003). Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity. Nat. Med. 9, 582-588.
    • (2003) Nat. Med. , vol.9 , pp. 582-588
    • Akbari, O.1    Stock, P.2    Meyer, E.3
  • 4
    • 79953765855 scopus 로고    scopus 로고
    • Adiponectin enhances insulin sensitivity by increasing hepatic IRS-2 expression via a macrophage-derived IL-6-dependent pathway
    • Awazawa, M., Ueki, K., Inabe, K., et al. (2011). Adiponectin enhances insulin sensitivity by increasing hepatic IRS-2 expression via a macrophage-derived IL-6-dependent pathway. Cell Metab. 13, 401-412.
    • (2011) Cell Metab. , vol.13 , pp. 401-412
    • Awazawa, M.1    Ueki, K.2    Inabe, K.3
  • 5
    • 84921467844 scopus 로고    scopus 로고
    • Macrophage recruitment in obese adipose tissue
    • Bai, Y., and Sun, Q. (2015). Macrophage recruitment in obese adipose tissue. Obes. Rev. 16, 127-136.
    • (2015) Obes. Rev. , vol.16 , pp. 127-136
    • Bai, Y.1    Sun, Q.2
  • 6
    • 0034881391 scopus 로고    scopus 로고
    • The adipocyte-secreted protein Acrp30 enhances hepatic insulin action
    • Berg, A.H., Combs, T.P., Du, X., et al. (2001). The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nat. Med. 7, 947-953.
    • (2001) Nat. Med. , vol.7 , pp. 947-953
    • Berg, A.H.1    Combs, T.P.2    Du, X.3
  • 7
    • 84926638214 scopus 로고    scopus 로고
    • Complement, c1q, and c1q-relatedmolecules regulatemacrophagepolarization
    • Bohlson, S.S., O'Conner, S.D., Hulsebus, H.J., et al. (2014). Complement, c1q, and c1q-relatedmolecules regulatemacrophagepolarization. Front. Immunol.5, 402.
    • (2014) Front. Immunol. , vol.5 , pp. 402
    • Bohlson, S.S.1    O'Conner, S.D.2    Hulsebus, H.J.3
  • 8
    • 70349395711 scopus 로고    scopus 로고
    • Role of macrophage tissue infiltration in obesity and insulin resistance
    • Bourlier, V., and Bouloumie, A. (2009). Role of macrophage tissue infiltration in obesity and insulin resistance. Diabetes Metab. 35, 251-260.
    • (2009) Diabetes Metab. , vol.35 , pp. 251-260
    • Bourlier, V.1    Bouloumie, A.2
  • 9
    • 84924969384 scopus 로고    scopus 로고
    • Group 2 innate lymphoid cells promote beigingof white adipose tissue and limit obesity
    • Brestoff, J.R., Kim, B.S., Saenz, S.A., et al. (2015). Group 2 innate lymphoid cells promote beigingof white adipose tissue and limit obesity.Nature 519, 242-246.
    • (2015) Nature , vol.519 , pp. 242-246
    • Brestoff, J.R.1    Kim, B.S.2    Saenz, S.A.3
  • 10
    • 84920950343 scopus 로고    scopus 로고
    • IL-33: An alarmin cytokine with crucial roles in innate immunity, inflammation and allergy
    • Cayrol, C., and Girard, J.P. (2014). IL-33: an alarmin cytokine with crucial roles in innate immunity, inflammation and allergy. Curr. Opin. Immunol. 31, 31-37.
    • (2014) Curr. Opin. Immunol. , vol.31 , pp. 31-37
    • Cayrol, C.1    Girard, J.P.2
  • 11
    • 80355133234 scopus 로고    scopus 로고
    • Macrophage-mediated inflammation in metabolic disease
    • Chawla, A., Nguyen, K.D., and Goh, Y.P. (2011). Macrophage-mediated inflammation in metabolic disease. Nat. Rev. Immunol. 11, 738-749.
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 738-749
    • Chawla, A.1    Nguyen, K.D.2    Goh, Y.P.3
  • 12
    • 84856006742 scopus 로고    scopus 로고
    • Adiponectin and its globular fragment differentially modulate the oxidative burst of primary human phagocytes
    • Chedid, P., Hurtado-Nedelec, M., Marion-Gaber, B., et al. (2012). Adiponectin and its globular fragment differentially modulate the oxidative burst of primary human phagocytes. Am. J. Pathol. 180, 682-692.
    • (2012) Am. J. Pathol. , vol.180 , pp. 682-692
    • Chedid, P.1    Hurtado-Nedelec, M.2    Marion-Gaber, B.3
  • 13
    • 84898669986 scopus 로고    scopus 로고
    • Adipose tissue dendritic cells enhances inflammation by prompting the generation of Th17 cells
    • Chen, Y., Tian, J., Tian, X., et al. (2014). Adipose tissue dendritic cells enhances inflammation by prompting the generation of Th17 cells. PLoS One 9, e92450.
    • (2014) PLoS One , vol.9
    • Chen, Y.1    Tian, J.2    Tian, X.3
  • 14
    • 84929156825 scopus 로고    scopus 로고
    • Homeostatic regulation of T cell trafficking by a B cell-derived peptide is impaired in autoimmune and chronic inflammatory disease
    • Chimen, M., McGettrick, H.M., Apta, B., et al. (2015). Homeostatic regulation of T cell trafficking by a B cell-derived peptide is impaired in autoimmune and chronic inflammatory disease. Nat. Med. 21, 467-475.
    • (2015) Nat. Med. , vol.21 , pp. 467-475
    • Chimen, M.1    McGettrick, H.M.2    Apta, B.3
  • 15
    • 0347986520 scopus 로고    scopus 로고
    • Expression of adiponectin receptors in human macrophages and regulation by agonists of the nuclear receptors PPARa, PPARg, and LXR
    • Chinetti, G., Zawadski, C., Fruchart, J.C., et al. (2004). Expression of adiponectin receptors in human macrophages and regulation by agonists of the nuclear receptors PPARa, PPARg, and LXR. Biochem. Biophys. Res. Commun. 314, 151-158.
    • (2004) Biochem. Biophys. Res. Commun. , vol.314 , pp. 151-158
    • Chinetti, G.1    Zawadski, C.2    Fruchart, J.C.3
  • 16
    • 84925431240 scopus 로고    scopus 로고
    • Obesity impairs gd T cell homeostasis and antiviral function in humans
    • Costanzo, A.E., Taylor, K.R., Dutt, S., et al. (2015). Obesity impairs gd T cell homeostasis and antiviral function in humans. PLoS One 10, e0120918.
    • (2015) PLoS One , vol.10
    • Costanzo, A.E.1    Taylor, K.R.2    Dutt, S.3
  • 17
    • 78649822277 scopus 로고    scopus 로고
    • T-cadherin is critical for adiponectin-mediated cardioprotectioninmice
    • Denzel, M.S., Scimia, M.C., Zumstein, P.M., et al. (2010). T-cadherin is critical for adiponectin-mediated cardioprotectioninmice. J.Clin. Invest. 120, 4342-4352.
    • (2010) J.Clin. Invest. , vol.120 , pp. 4342-4352
    • Denzel, M.S.1    Scimia, M.C.2    Zumstein, P.M.3
  • 18
    • 65649117802 scopus 로고    scopus 로고
    • Unexpected trafficking of immune cells within the adipose tissue during the onset of obesity
    • Duffaut, C., Galitzky, J., Lafontan, M., et al. (2009). Unexpected trafficking of immune cells within the adipose tissue during the onset of obesity. Biochem. Biophys. Res. Commun. 384, 482-485.
    • (2009) Biochem. Biophys. Res. Commun. , vol.384 , pp. 482-485
    • Duffaut, C.1    Galitzky, J.2    Lafontan, M.3
  • 19
    • 84906794224 scopus 로고    scopus 로고
    • The multifaceted and controversial immunometabolic actions of adiponectin
    • Esmaili, S., Xu, A., and George, J. (2014). The multifaceted and controversial immunometabolic actions of adiponectin. Trends Endocrinol. Metab. 25, 444-451.
    • (2014) Trends Endocrinol. Metab. , vol.25 , pp. 444-451
    • Esmaili, S.1    Xu, A.2    George, J.3
  • 20
    • 21344463079 scopus 로고    scopus 로고
    • Serum high molecular weight complex of adiponectin correlates better with glucose tolerance than total serum adiponectin in Indo-Asian males
    • Fisher, F.M., Trujillo, M.E., Hanif, W., et al. (2005). Serum high molecular weight complex of adiponectin correlates better with glucose tolerance than total serum adiponectin in Indo-Asian males. Diabetologia 48, 1084-1087.
    • (2005) Diabetologia , vol.48 , pp. 1084-1087
    • Fisher, F.M.1    Trujillo, M.E.2    Hanif, W.3
  • 21
    • 84908609269 scopus 로고    scopus 로고
    • Complement protein C1q and adiponectin stimulate Mer tyrosine kinase-dependent engulfment of apoptotic cells through a shared pathway
    • Galvan, M.D., Hulsebus, H., Heitker, T., et al. (2014). Complement protein C1q and adiponectin stimulate Mer tyrosine kinase-dependent engulfment of apoptotic cells through a shared pathway. J. Innate Immun. 6, 780-792.
    • (2014) J. Innate Immun. , vol.6 , pp. 780-792
    • Galvan, M.D.1    Hulsebus, H.2    Heitker, T.3
  • 22
    • 4544241860 scopus 로고    scopus 로고
    • Adiponectin, the missing link in insulin resistance and obesity
    • Gil-Campos, M., Canete, R.R., and Gil, A. (2004). Adiponectin, the missing link in insulin resistance and obesity. Clin. Nutr. 23, 963-974.
    • (2004) Clin. Nutr. , vol.23 , pp. 963-974
    • Gil-Campos, M.1    Canete, R.R.2    Gil, A.3
  • 23
    • 33644779729 scopus 로고    scopus 로고
    • Immunosurveillance and immunoregulation by gd T cells
    • Girardi, M. (2006). Immunosurveillance and immunoregulation by gd T cells. J. Invest. Dermatol. 126, 25-31.
    • (2006) J. Invest. Dermatol. , vol.126 , pp. 25-31
    • Girardi, M.1
  • 24
    • 2942687834 scopus 로고    scopus 로고
    • Adiponectin: A novel adipokine linking adipocytes and vascular function
    • Goldstein, B.J., and Scalia, R. (2004). Adiponectin: A novel adipokine linking adipocytes and vascular function. J. Clin. Endocrinol. Metab. 89, 2563-2568.
    • (2004) J. Clin. Endocrinol. Metab. , vol.89 , pp. 2563-2568
    • Goldstein, B.J.1    Scalia, R.2
  • 25
    • 28544446111 scopus 로고    scopus 로고
    • Monocyte and macrophage heterogeneity
    • Gordon, S., and Taylor, P.R. (2005). Monocyte and macrophage heterogeneity. Nat. Rev. Immunol. 5, 953-964.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 953-964
    • Gordon, S.1    Taylor, P.R.2
  • 26
    • 1942534687 scopus 로고    scopus 로고
    • Adiponectin and its role in the obesity-induced insulin resistance and related complications
    • Haluzik, M., Parizkova, J., and Haluzik, M.M. (2004). Adiponectin and its role in the obesity-induced insulin resistance and related complications. Physiol. Res. 53, 123-129.
    • (2004) Physiol. Res. , vol.53 , pp. 123-129
    • Haluzik, M.1    Parizkova, J.2    Haluzik, M.M.3
  • 27
    • 1642299047 scopus 로고    scopus 로고
    • Adipose tissue adiponectin production and adiponectin serum concentration in human obesity and insulin resistance
    • Hoffstedt, J., Arvidsson, E., Sjolin, E., et al. (2004). Adipose tissue adiponectin production and adiponectin serum concentration in human obesity and insulin resistance. J. Clin. Endocrinol. Metab. 89, 1391-1396.
    • (2004) J. Clin. Endocrinol. Metab. , vol.89 , pp. 1391-1396
    • Hoffstedt, J.1    Arvidsson, E.2    Sjolin, E.3
  • 28
    • 78651260799 scopus 로고    scopus 로고
    • Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin
    • Holland, W.L., Miller, R.A., Wang, Z.V., et al. (2011). Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin. Nat. Med. 17, 55-63.
    • (2011) Nat. Med. , vol.17 , pp. 55-63
    • Holland, W.L.1    Miller, R.A.2    Wang, Z.V.3
  • 29
    • 17544382289 scopus 로고    scopus 로고
    • AdipoQ is a novel adiposespecific gene dysregulated in obesity
    • Hu, E., Liang, P., and Spiegelman, B.M. (1996). AdipoQ is a novel adiposespecific gene dysregulated in obesity. J. Biol. Chem. 271, 10697-10703.
    • (1996) J. Biol. Chem. , vol.271 , pp. 10697-10703
    • Hu, E.1    Liang, P.2    Spiegelman, B.M.3
  • 30
    • 84938747174 scopus 로고    scopus 로고
    • Adiponectin enhances cold-induced browning of subcutaneous adipose tissue via promotingM2 macrophage proliferation
    • Hui, X., Gu, P., Zhang, J., et al. (2015). Adiponectin enhances cold-induced browning of subcutaneous adipose tissue via promotingM2 macrophage proliferation. Cell Metab. 22, 279-290.
    • (2015) Cell Metab. , vol.22 , pp. 279-290
    • Hui, X.1    Gu, P.2    Zhang, J.3
  • 32
    • 84863295568 scopus 로고    scopus 로고
    • Adiponectin induces dendritic cell activation via PLCg/JNK/NF-kB pathways, leading to Th1 and Th17 polarization
    • Jung, M.Y., Kim, H.S., Hong, H.J., et al. (2012). Adiponectin induces dendritic cell activation via PLCg/JNK/NF-kB pathways, leading to Th1 and Th17 polarization. J. Immunol. 188, 2592-2601.
    • (2012) J. Immunol. , vol.188 , pp. 2592-2601
    • Jung, M.Y.1    Kim, H.S.2    Hong, H.J.3
  • 33
    • 18844432308 scopus 로고    scopus 로고
    • Adiponectin and adiponectin receptors
    • Kadowaki, T., and Yamauchi, T. (2005). Adiponectin and adiponectin receptors. Endocr. Rev. 26, 439-451.
    • (2005) Endocr. Rev. , vol.26 , pp. 439-451
    • Kadowaki, T.1    Yamauchi, T.2
  • 34
    • 33745834319 scopus 로고    scopus 로고
    • Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome
    • Kadowaki, T., Yamauchi, T., Kubota, N., et al. (2006). Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome. J. Clin. Invest. 116, 1784-1792.
    • (2006) J. Clin. Invest. , vol.116 , pp. 1784-1792
    • Kadowaki, T.1    Yamauchi, T.2    Kubota, N.3
  • 35
    • 84878783089 scopus 로고    scopus 로고
    • Adiponectin regulates bone mass via opposite central and peripheral mechanisms through FoxO1
    • Kajimura, D., Lee, H.W., Riley, K.J., et al. (2013). Adiponectin regulates bone mass via opposite central and peripheral mechanisms through FoxO1. Cell Metab. 17, 901-915.
    • (2013) Cell Metab. , vol.17 , pp. 901-915
    • Kajimura, D.1    Lee, H.W.2    Riley, K.J.3
  • 36
    • 44349112305 scopus 로고    scopus 로고
    • Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity
    • Kang, K., Reilly, S.M., Karabacak, V., et al. (2008). Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity. Cell Metab. 7, 485-495.
    • (2008) Cell Metab. , vol.7 , pp. 485-495
    • Kang, K.1    Reilly, S.M.2    Karabacak, V.3
  • 37
    • 33646470282 scopus 로고    scopus 로고
    • Adiponectin is a negative regulator of NK cell cytotoxicity
    • Kim, K.Y., Kim, J.K., Han, S.H., et al. (2006). Adiponectin is a negative regulator of NK cell cytotoxicity. J. Immunol. 176, 5958-5964.
    • (2006) J. Immunol. , vol.176 , pp. 5958-5964
    • Kim, K.Y.1    Kim, J.K.2    Han, S.H.3
  • 38
    • 46249117032 scopus 로고    scopus 로고
    • T-lymphocyte infiltration in visceral adipose tissue: A primary event in adipose tissue inflammation and the development of obesity-mediated insulin resistance
    • Kintscher, U., Hartge, M., Hess, K., et al. (2008). T-lymphocyte infiltration in visceral adipose tissue: a primary event in adipose tissue inflammation and the development of obesity-mediated insulin resistance. Arterioscler. Thromb. Vasc. Biol. 28, 1304-1310.
    • (2008) Arterioscler. Thromb. Vasc. Biol. , vol.28 , pp. 1304-1310
    • Kintscher, U.1    Hartge, M.2    Hess, K.3
  • 39
    • 84935085624 scopus 로고    scopus 로고
    • Emerging and novel functions of complement protein C1q
    • Kouser, L., Madhukaran, S.P., Shastri, A., et al. (2015). Emerging and novel functions of complement protein C1q. Front. Immunol. 6, 317.
    • (2015) Front. Immunol. , vol.6 , pp. 317
    • Kouser, L.1    Madhukaran, S.P.2    Shastri, A.3
  • 40
    • 84876803074 scopus 로고    scopus 로고
    • Th2-type innateimmuneresponses mediatedby natural helper cells
    • Koyasu, S., and Moro, K. (2013). Th2-type innateimmuneresponses mediatedby natural helper cells. Ann. NY Acad. Sci. 1283, 43-49.
    • (2013) Ann. NY Acad. Sci. , vol.1283 , pp. 43-49
    • Koyasu, S.1    Moro, K.2
  • 41
    • 34347255023 scopus 로고    scopus 로고
    • Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake
    • Kubota, N., Yano, W., Kubota, T., et al. (2007). Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake. Cell Metab. 6, 55-68.
    • (2007) Cell Metab. , vol.6 , pp. 55-68
    • Kubota, N.1    Yano, W.2    Kubota, T.3
  • 42
    • 84949627236 scopus 로고    scopus 로고
    • Regulation of metabolism by the innate immune system
    • Lackey, D.E., and Olefsky, J.M. (2016). Regulation of metabolism by the innate immune system. Nat. Rev. Endocrinol. 12, 15-28.
    • (2016) Nat. Rev. Endocrinol. , vol.12 , pp. 15-28
    • Lackey, D.E.1    Olefsky, J.M.2
  • 43
    • 23044436608 scopus 로고    scopus 로고
    • Leptin and adiponectin stimulate the release of proinflammatory cytokines and prostaglandins from human placenta and maternal adipose tissue via nuclear factor-kB, peroxisomal proliferator-activated receptor-g and extracellularly regulated kinase 1/2
    • Lappas, M., Permezel, M., and Rice, G.E. (2005). Leptin and adiponectin stimulate the release of proinflammatory cytokines and prostaglandins from human placenta and maternal adipose tissue via nuclear factor-kB, peroxisomal proliferator-activated receptor-g and extracellularly regulated kinase 1/2. Endocrinology 146, 3334-3342.
    • (2005) Endocrinology , vol.146 , pp. 3334-3342
    • Lappas, M.1    Permezel, M.2    Rice, G.E.3
  • 44
    • 84920940721 scopus 로고    scopus 로고
    • Activated type 2 innate lymphoid cells regulate beige fat biogenesis
    • Lee, M.W., Odegaard, J.I., Mukundan, L., et al. (2015). Activated type 2 innate lymphoid cells regulate beige fat biogenesis. Cell 160, 74-87.
    • (2015) Cell , vol.160 , pp. 74-87
    • Lee, M.W.1    Odegaard, J.I.2    Mukundan, L.3
  • 45
    • 84878261946 scopus 로고    scopus 로고
    • TH2, allergy and group 2 innate lymphoid cells
    • Licona-Limon, P., Kim, L.K., Palm, N.W., et al. (2013). TH2, allergy and group 2 innate lymphoid cells. Nat. Immunol. 14, 536-542.
    • (2013) Nat. Immunol. , vol.14 , pp. 536-542
    • Licona-Limon, P.1    Kim, L.K.2    Palm, N.W.3
  • 46
    • 77951184667 scopus 로고    scopus 로고
    • Macrophage adiponectin expression improves insulin sensitivity and protects against inflammation and atherosclerosis
    • Luo, N., Liu, J., Chung, B.H., et al. (2010). Macrophage adiponectin expression improves insulin sensitivity and protects against inflammation and atherosclerosis. Diabetes 59, 791-799.
    • (2010) Diabetes , vol.59 , pp. 791-799
    • Luo, N.1    Liu, J.2    Chung, B.H.3
  • 47
    • 79959603581 scopus 로고    scopus 로고
    • Effects of macrophage-specific adiponectin expression on lipid metabolism in vivo
    • Luo, N., Wang, X., Chung, B.H., et al. (2011). Effects of macrophage-specific adiponectin expression on lipid metabolism in vivo. Am. J. Physiol. Endocrinol. Metab. 301, E180-E186.
    • (2011) Am. J. Physiol. Endocrinol. Metab. , vol.301 , pp. E180-E186
    • Luo, N.1    Wang, X.2    Chung, B.H.3
  • 48
    • 69249155107 scopus 로고    scopus 로고
    • Invariant NKT cells and CD1d+ cells amass in human omentum and are depleted in patients with cancer and obesity
    • Lynch, L., O'Shea, D., Winter, D.C., et al. (2009). Invariant NKT cells and CD1d+ cells amass in human omentum and are depleted in patients with cancer and obesity. Eur. J. Immunol. 39, 1893-1901.
    • (2009) Eur. J. Immunol. , vol.39 , pp. 1893-1901
    • Lynch, L.1    O'Shea, D.2    Winter, D.C.3
  • 49
    • 84866520055 scopus 로고    scopus 로고
    • Adipose tissue invariant NKT cells protect against diet-induced obesity and metabolic disorder through regulatory cytokine production
    • Lynch, L., Nowak, M., Varghese, B., et al. (2012). Adipose tissue invariant NKT cells protect against diet-induced obesity and metabolic disorder through regulatory cytokine production. Immunity 37, 574-587.
    • (2012) Immunity , vol.37 , pp. 574-587
    • Lynch, L.1    Nowak, M.2    Varghese, B.3
  • 50
    • 0029980285 scopus 로고    scopus 로고
    • CDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (adipose most abundant gene transcript 1)
    • Maeda, K., Okubo, K., Shimomura, I., et al. (1996). cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (adipose most abundant gene transcript 1). Biochem. Biophys. Res. Commun. 221, 286-289.
    • (1996) Biochem. Biophys. Res. Commun. , vol.221 , pp. 286-289
    • Maeda, K.1    Okubo, K.2    Shimomura, I.3
  • 51
    • 0036063777 scopus 로고    scopus 로고
    • Diet-induced insulin resistance in mice lacking adiponectin/ACRP30
    • Maeda, N., Shimomura, I., Kishida, K., et al. (2002). Diet-induced insulin resistance in mice lacking adiponectin/ACRP30. Nat. Med. 8, 731-737.
    • (2002) Nat. Med. , vol.8 , pp. 731-737
    • Maeda, N.1    Shimomura, I.2    Kishida, K.3
  • 52
    • 77950625277 scopus 로고    scopus 로고
    • The anti-inflammatory effects of adiponectin are mediated via a heme oxygenase-1-dependent pathway in rat Kupffer cells
    • Mandal, P., Park, P.H., McMullen, M.R., et al. (2010a). The anti-inflammatory effects of adiponectin are mediated via a heme oxygenase-1-dependent pathway in rat Kupffer cells. Hepatology 51, 1420-1429.
    • (2010) Hepatology , vol.51 , pp. 1420-1429
    • Mandal, P.1    Park, P.H.2    McMullen, M.R.3
  • 53
    • 78049492112 scopus 로고    scopus 로고
    • Adiponectin and heme oxygenase-1 suppress TLR4/MyD88-independent signaling in rat Kupffer cells and in mice after chronic ethanol exposure
    • Mandal, P., Roychowdhury, S., Park, P.H., et al. (2010b). Adiponectin and heme oxygenase-1 suppress TLR4/MyD88-independent signaling in rat Kupffer cells and in mice after chronic ethanol exposure. J. Immunol. 185, 4928-4937.
    • (2010) J. Immunol. , vol.185 , pp. 4928-4937
    • Mandal, P.1    Roychowdhury, S.2    Park, P.H.3
  • 54
    • 79953863868 scopus 로고    scopus 로고
    • Molecular mechanism for adiponectin-dependentM2 macrophage polarization: Link between the metabolic and innate immune activity of full-length adiponectin
    • Mandal, P., Pratt, B.T., Barnes, M., et al. (2011). Molecular mechanism for adiponectin-dependentM2 macrophage polarization: link between the metabolic and innate immune activity of full-length adiponectin. J. Biol. Chem. 286, 13460-13469.
    • (2011) J. Biol. Chem. , vol.286 , pp. 13460-13469
    • Mandal, P.1    Pratt, B.T.2    Barnes, M.3
  • 55
    • 7644231561 scopus 로고    scopus 로고
    • The chemokine system in diverse forms of macrophage activation and polarization
    • Mantovani, A., Sica, A., Sozzani, S., et al. (2004). The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol. 25, 677-686.
    • (2004) Trends Immunol. , vol.25 , pp. 677-686
    • Mantovani, A.1    Sica, A.2    Sozzani, S.3
  • 56
    • 84871076444 scopus 로고    scopus 로고
    • Macrophage plasticity and polarization in tissue repair and remodelling
    • Mantovani, A., Biswas, S.K., Galdiero, M.R., et al. (2013). Macrophage plasticity and polarization in tissue repair and remodelling. J. Pathol. 229, 176-185.
    • (2013) J. Pathol. , vol.229 , pp. 176-185
    • Mantovani, A.1    Biswas, S.K.2    Galdiero, M.R.3
  • 57
    • 70349160768 scopus 로고    scopus 로고
    • Adiponectin deficiency increases allergic airway inflammation and pulmonary vascular remodeling
    • Medoff, B.D., Okamoto, Y., Leyton, P., et al. (2009). Adiponectin deficiency increases allergic airway inflammation and pulmonary vascular remodeling. Am. J. Respir. Cell Mol. Biol. 41, 397-406.
    • (2009) Am. J. Respir. Cell Mol. Biol. , vol.41 , pp. 397-406
    • Medoff, B.D.1    Okamoto, Y.2    Leyton, P.3
  • 58
    • 84925287282 scopus 로고    scopus 로고
    • Gd T cells promote inflammation and insulin resistance during high fat diet-induced obesity in mice
    • Mehta, P., Nuotio-Antar, A.M., and Smith, C.W. (2015). gd T cells promote inflammation and insulin resistance during high fat diet-induced obesity in mice. J. Leukoc. Biol. 97, 121-134.
    • (2015) J. Leukoc. Biol. , vol.97 , pp. 121-134
    • Mehta, P.1    Nuotio-Antar, A.M.2    Smith, C.W.3
  • 59
    • 84876746655 scopus 로고    scopus 로고
    • Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages
    • Molofsky, A.B., Nussbaum, J.C., Liang, H.E., et al. (2013). Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages. J. Exp. Med. 210, 535-549.
    • (2013) J. Exp. Med. , vol.210 , pp. 535-549
    • Molofsky, A.B.1    Nussbaum, J.C.2    Liang, H.E.3
  • 60
    • 82555186955 scopus 로고    scopus 로고
    • Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis
    • Nguyen, K.D., Qiu, Y., Cui, X., et al. (2011). Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis. Nature 480, 104-108.
    • (2011) Nature , vol.480 , pp. 104-108
    • Nguyen, K.D.1    Qiu, Y.2    Cui, X.3
  • 61
    • 79751496064 scopus 로고    scopus 로고
    • Alternative macrophage activation and metabolism
    • Odegaard, J.I., and Chawla, A. (2011). Alternative macrophage activation and metabolism. Annu. Rev. Pathol. 6, 275-297.
    • (2011) Annu. Rev. Pathol. , vol.6 , pp. 275-297
    • Odegaard, J.I.1    Chawla, A.2
  • 62
    • 77949881805 scopus 로고    scopus 로고
    • Adiponectin promotes macrophage polarization toward an anti-inflammatory phenotype
    • Ohashi, K., Parker, J.L., Ouchi, N., et al. (2010). Adiponectin promotes macrophage polarization toward an anti-inflammatory phenotype. J. Biol. Chem. 285, 6153-6160.
    • (2010) J. Biol. Chem. , vol.285 , pp. 6153-6160
    • Ohashi, K.1    Parker, J.L.2    Ouchi, N.3
  • 63
    • 0035957040 scopus 로고    scopus 로고
    • Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages
    • Ouchi, N., Kihara, S., Arita, Y., et al. (2001). Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages. Circulation 103, 1057-1063.
    • (2001) Circulation , vol.103 , pp. 1057-1063
    • Ouchi, N.1    Kihara, S.2    Arita, Y.3
  • 64
    • 0347334429 scopus 로고    scopus 로고
    • Obesity, adiponectin and vascular inflammatory disease
    • Ouchi, N., Kihara, S., Funahashi, T., et al. (2003). Obesity, adiponectin and vascular inflammatory disease. Curr. Opin. Lipidol. 14, 561-566.
    • (2003) Curr. Opin. Lipidol. , vol.14 , pp. 561-566
    • Ouchi, N.1    Kihara, S.2    Funahashi, T.3
  • 65
    • 0346463030 scopus 로고    scopus 로고
    • Adiponectin stimulates angiogenesis by promoting cross-talk between AMP-activated protein kinase and Akt signaling in endothelial cells
    • Ouchi, N., Kobayashi, H., Kihara, S., et al. (2004). Adiponectin stimulates angiogenesis by promoting cross-talk between AMP-activated protein kinase and Akt signaling in endothelial cells. J. Biol. Chem. 279, 1304-1309.
    • (2004) J. Biol. Chem. , vol.279 , pp. 1304-1309
    • Ouchi, N.1    Kobayashi, H.2    Kihara, S.3
  • 66
    • 11144355637 scopus 로고    scopus 로고
    • Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedionemediated improvement in insulin sensitivity
    • Pajvani, U.B., Hawkins, M., Combs, T.P., et al. (2004). Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedionemediated improvement in insulin sensitivity. J. Biol. Chem. 279, 12152-12162.
    • (2004) J. Biol. Chem. , vol.279 , pp. 12152-12162
    • Pajvani, U.B.1    Hawkins, M.2    Combs, T.P.3
  • 67
    • 34547556455 scopus 로고    scopus 로고
    • Short-term treatment of RAW264.7 macrophages with adiponectin increases tumor necrosis factor - A (TNF - A) expression via ERK1/2 activation and Egr-1 expression: Role of TNF - A in adiponectin-stimulated interleukin-10 production
    • Park, P.H., McMullen, M.R., Huang, H., et al. (2007). Short-term treatment of RAW264.7 macrophages with adiponectin increases tumor necrosis factor-a (TNF-a) expression via ERK1/2 activation and Egr-1 expression: role of TNF-a in adiponectin-stimulated interleukin-10 production. J. Biol. Chem. 282, 21695-21703.
    • (2007) J. Biol. Chem. , vol.282 , pp. 21695-21703
    • Park, P.H.1    McMullen, M.R.2    Huang, H.3
  • 68
    • 46949110015 scopus 로고    scopus 로고
    • Activation of cyclic-AMP response element binding protein contributes to adiponectin-stimulated interleukin-10 expression in RAW 264.7 macrophages
    • Park, P.H., Huang, H., McMullen, M.R., et al. (2008a). Activation of cyclic-AMP response element binding protein contributes to adiponectin-stimulated interleukin-10 expression in RAW 264.7 macrophages. J. Leukoc. Biol. 83, 1258-1266.
    • (2008) J. Leukoc. Biol. , vol.83 , pp. 1258-1266
    • Park, P.H.1    Huang, H.2    McMullen, M.R.3
  • 69
    • 55249083318 scopus 로고    scopus 로고
    • Suppression of lipopolysaccharide-stimulated tumor necrosis factor - A production by adiponectin is mediated by transcriptional and post-transcriptional mechanisms
    • Park, P.H., Huang, H., McMullen, M.R., et al. (2008b). Suppression of lipopolysaccharide-stimulated tumor necrosis factor-a production by adiponectin is mediated by transcriptional and post-transcriptional mechanisms. J. Biol. Chem. 283, 26850-26858.
    • (2008) J. Biol. Chem. , vol.283 , pp. 26850-26858
    • Park, P.H.1    Huang, H.2    McMullen, M.R.3
  • 70
    • 1842864234 scopus 로고    scopus 로고
    • Plasma adiponectin levels and risk of myocardial infarction in men
    • Pischon, T., Girman, C.J., Hotamisligil, G.S., et al. (2004). Plasma adiponectin levels and risk of myocardial infarction in men. JAMA 291, 1730-1737.
    • (2004) JAMA , vol.291 , pp. 1730-1737
    • Pischon, T.1    Girman, C.J.2    Hotamisligil, G.S.3
  • 71
    • 77954926597 scopus 로고    scopus 로고
    • Systemically dispersed innate IL-13-expressing cells in type 2 immunity
    • Price, A.E., Liang, H.E., Sullivan, B.M., et al. (2010). Systemically dispersed innate IL-13-expressing cells in type 2 immunity. Proc. Natl Acad. Sci. USA 107, 11489-11494.
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 11489-11494
    • Price, A.E.1    Liang, H.E.2    Sullivan, B.M.3
  • 72
    • 84898599881 scopus 로고    scopus 로고
    • Adiponectin reduces thermogenesis by inhibiting brown adipose tissue activation in mice
    • Qiao, L., Yoo, H., Bosco, C., et al. (2014). Adiponectin reduces thermogenesis by inhibiting brown adipose tissue activation in mice. Diabetologia 57, 1027-1036.
    • (2014) Diabetologia , vol.57 , pp. 1027-1036
    • Qiao, L.1    Yoo, H.2    Bosco, C.3
  • 73
    • 84902094655 scopus 로고    scopus 로고
    • Eosinophils and type 2 cytokine signaling in macrophages orchestrate development of functional beige fat
    • Qiu, Y., Nguyen, K.D., Odegaard, J.I., et al. (2014). Eosinophils and type 2 cytokine signaling in macrophages orchestrate development of functional beige fat. Cell 157, 1292-1308.
    • (2014) Cell , vol.157 , pp. 1292-1308
    • Qiu, Y.1    Nguyen, K.D.2    Odegaard, J.I.3
  • 74
    • 84902097377 scopus 로고    scopus 로고
    • Meteorin-like is ahormone that regulates immune-adipose interactions to increase beige fat thermogenesis
    • Rao, R.R., Long, J.Z., White, J.P., et al. (2014). Meteorin-like is ahormone that regulates immune-adipose interactions to increase beige fat thermogenesis. Cell 157, 1279-1291.
    • (2014) Cell , vol.157 , pp. 1279-1291
    • Rao, R.R.1    Long, J.Z.2    White, J.P.3
  • 75
    • 84880782020 scopus 로고    scopus 로고
    • Adiponectin inhibits neutrophil phagocytosis of Escherichia coli by inhibition of PKB and ERK 1/2 MAPK signalling and Mac-1 activation
    • Rossi, A., and Lord, J. (2013a). Adiponectin inhibits neutrophil phagocytosis of Escherichia coli by inhibition of PKB and ERK 1/2 MAPK signalling and Mac-1 activation. PLoS One 8, e69108.
    • (2013) PLoS One , vol.8
    • Rossi, A.1    Lord, J.2
  • 76
    • 84889096628 scopus 로고    scopus 로고
    • Adiponectin inhibits neutrophil apoptosis via activation of AMP kinase, PKB and ERK 1/2 MAP kinase
    • Rossi, A., and Lord, J.M. (2013b). Adiponectin inhibits neutrophil apoptosis via activation of AMP kinase, PKB and ERK 1/2 MAP kinase. Apoptosis 18, 1469-1480.
    • (2013) Apoptosis , vol.18 , pp. 1469-1480
    • Rossi, A.1    Lord, J.M.2
  • 77
    • 0028787490 scopus 로고
    • A novel serum protein similar to C1q, produced exclusively in adipocytes
    • Scherer, P.E., Williams, S., Fogliano, M., et al. (1995). A novel serum protein similar to C1q, produced exclusively in adipocytes. J. Biol. Chem. 270, 26746-26749.
    • (1995) J. Biol. Chem. , vol.270 , pp. 26746-26749
    • Scherer, P.E.1    Williams, S.2    Fogliano, M.3
  • 78
    • 27144457438 scopus 로고    scopus 로고
    • Adiponectin protects against myocardial ischemia-reperfusion injury throughAMPK-and COX-2-dependent mechanisms
    • Shibata, R., Sato, K., Pimentel, D.R., et al. (2005). Adiponectin protects against myocardial ischemia-reperfusion injury throughAMPK-and COX-2-dependent mechanisms. Nat. Med. 11, 1096-1103.
    • (2005) Nat. Med. , vol.11 , pp. 1096-1103
    • Shibata, R.1    Sato, K.2    Pimentel, D.R.3
  • 79
    • 84955166784 scopus 로고    scopus 로고
    • Adiponectin regulates psoriasiform skin inflammation by suppressing IL-17 production from gd-T cells
    • Shibata, S., Tada, Y., Hau, C.S., et al. (2015). Adiponectin regulates psoriasiform skin inflammation by suppressing IL-17 production from gd-T cells. Nat. Commun. 6, 7687.
    • (2015) Nat. Commun. , vol.6 , pp. 7687
    • Shibata, S.1    Tada, Y.2    Hau, C.S.3
  • 80
    • 84865460082 scopus 로고    scopus 로고
    • Dendritic cells promote macrophage infiltration and comprise a substantial proportion of obesity-associated increases in CD11c+ cells in adipose tissue and liver
    • Stefanovic-Racic, M., Yang, X., Turner, M.S., et al. (2012). Dendritic cells promote macrophage infiltration and comprise a substantial proportion of obesity-associated increases in CD11c+ cells in adipose tissue and liver. Diabetes 61, 2330-2339.
    • (2012) Diabetes , vol.61 , pp. 2330-2339
    • Stefanovic-Racic, M.1    Yang, X.2    Turner, M.S.3
  • 81
    • 33846784058 scopus 로고    scopus 로고
    • Adiponectin modulates inflammatory reactions via calreticulin receptor-dependent clearance of early apoptotic bodies
    • Takemura, Y., Ouchi, N., Shibata, R., et al. (2007). Adiponectin modulates inflammatory reactions via calreticulin receptor-dependent clearance of early apoptotic bodies. J. Clin. Invest. 117, 375-386.
    • (2007) J. Clin. Invest. , vol.117 , pp. 375-386
    • Takemura, Y.1    Ouchi, N.2    Shibata, R.3
  • 82
    • 0037059013 scopus 로고    scopus 로고
    • Enhanced muscle fat oxidationand glucose transport by ACRP30 globular domain: Acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation
    • Tomas, E., Tsao, T.S., Saha, A.K., et al. (2002). Enhanced muscle fat oxidationand glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation. Proc. Natl Acad. Sci. USA 99, 16309-16313.
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 16309-16313
    • Tomas, E.1    Tsao, T.S.2    Saha, A.K.3
  • 83
    • 79954631240 scopus 로고    scopus 로고
    • Novel immunomodulatory effects of adiponectin on dendritic cell functions
    • Tsang, J.Y., Li, D., Ho, D., et al. (2011). Novel immunomodulatory effects of adiponectin on dendritic cell functions. Int. Immunopharmacol. 11, 604-609.
    • (2011) Int. Immunopharmacol. , vol.11 , pp. 604-609
    • Tsang, J.Y.1    Li, D.2    Ho, D.3
  • 84
    • 0037119375 scopus 로고    scopus 로고
    • Oligomerization state-dependent activation of NF-kB signaling pathway by adipocyte complement-related protein of 30 kDa (Acrp30)
    • Tsao, T.S., Murrey, H.E., Hug, C., et al. (2002). Oligomerization state-dependent activation of NF-kB signaling pathway by adipocyte complement-related protein of 30 kDa (Acrp30). J. Biol. Chem. 277, 29359-29362.
    • (2002) J. Biol. Chem. , vol.277 , pp. 29359-29362
    • Tsao, T.S.1    Murrey, H.E.2    Hug, C.3
  • 85
    • 24044486262 scopus 로고    scopus 로고
    • Adiponectin induces TNF - A and IL-6 in macrophages and promotes tolerance to itself and other pro-inflammatory stimuli
    • Tsatsanis, C., Zacharioudaki, V., Androulidaki, A., et al. (2005). Adiponectin induces TNF-a and IL-6 in macrophages and promotes tolerance to itself and other pro-inflammatory stimuli. Biochem. Biophys. Res. Commun. 335, 1254-1263.
    • (2005) Biochem. Biophys. Res. Commun. , vol.335 , pp. 1254-1263
    • Tsatsanis, C.1    Zacharioudaki, V.2    Androulidaki, A.3
  • 86
    • 33845611050 scopus 로고    scopus 로고
    • Peripheral factors in the metabolic syndrome: The pivotal role of adiponectin
    • Tsatsanis, C., Zacharioudaki, V., Androulidaki, A., et al. (2006). Peripheral factors in the metabolic syndrome: the pivotal role of adiponectin. Ann. NY Acad. Sci. 1083, 185-195.
    • (2006) Ann. NY Acad. Sci. , vol.1083 , pp. 185-195
    • Tsatsanis, C.1    Zacharioudaki, V.2    Androulidaki, A.3
  • 87
    • 33644664433 scopus 로고    scopus 로고
    • Peroxisome proliferatoractivated receptor (PPAR)a activation increases adiponectin receptors and reduces obesity-related inflammation in adipose tissue: Comparison of activation of PPARa, PPARg, and their combination
    • Tsuchida, A., Yamauchi, T., Takekawa, S., et al. (2005). Peroxisome proliferatoractivated receptor (PPAR)a activation increases adiponectin receptors and reduces obesity-related inflammation in adipose tissue: comparison of activation of PPARa, PPARg, and their combination. Diabetes 54, 3358-3370.
    • (2005) Diabetes , vol.54 , pp. 3358-3370
    • Tsuchida, A.1    Yamauchi, T.2    Takekawa, S.3
  • 88
    • 0348230958 scopus 로고    scopus 로고
    • Obesity is associated with macrophage accumulation in adipose tissue
    • Weisberg, S.P., McCann, D., Desai, M., et al. (2003). Obesity is associated with macrophage accumulation in adipose tissue. J. Clin. Invest. 112, 1796-1808.
    • (2003) J. Clin. Invest. , vol.112 , pp. 1796-1808
    • Weisberg, S.P.1    McCann, D.2    Desai, M.3
  • 89
    • 31044456529 scopus 로고    scopus 로고
    • CCR2 modulates inflammatory and metabolic effects of high-fat feeding
    • Weisberg, S.P., Hunter, D., Huber, R., et al. (2006). CCR2 modulates inflammatory and metabolic effects of high-fat feeding. J. Clin. Invest. 116, 115-124.
    • (2006) J. Clin. Invest. , vol.116 , pp. 115-124
    • Weisberg, S.P.1    Hunter, D.2    Huber, R.3
  • 90
    • 84925627014 scopus 로고    scopus 로고
    • NK cells link obesity-induced adipose stress to inflammation and insulin resistance
    • Wensveen, F.M., Jelencic, V., Valentic, S., et al. (2015). NK cells link obesity-induced adipose stress to inflammation and insulin resistance. Nat. Immunol. 16, 376-385.
    • (2015) Nat. Immunol. , vol.16 , pp. 376-385
    • Wensveen, F.M.1    Jelencic, V.2    Valentic, S.3
  • 91
    • 84876433299 scopus 로고    scopus 로고
    • Adiponectin modulates NK-cell function
    • Wilk, S., Jenke, A., Stehr, J., et al. (2013). Adiponectin modulates NK-cell function. Eur. J. Immunol. 43, 1024-1033.
    • (2013) Eur. J. Immunol. , vol.43 , pp. 1024-1033
    • Wilk, S.1    Jenke, A.2    Stehr, J.3
  • 92
    • 4544334655 scopus 로고    scopus 로고
    • Adiponectin induces the antiinflammatory cytokines IL-10 and IL-1RA in human leukocytes
    • Wolf, A.M., Wolf, D., Rumpold, H., et al. (2004). Adiponectin induces the antiinflammatory cytokines IL-10 and IL-1RA in human leukocytes. Biochem. Biophys. Res. Commun. 323, 630-635.
    • (2004) Biochem. Biophys. Res. Commun. , vol.323 , pp. 630-635
    • Wolf, A.M.1    Wolf, D.2    Rumpold, H.3
  • 93
    • 77955739070 scopus 로고    scopus 로고
    • Neutrophil functionin inflammation and inflammatory diseases
    • Wright, H.L., Moots, R.J., Bucknall, R.C., et al. (2010).Neutrophil functionin inflammation and inflammatory diseases. Rheumatology (Oxford) 49, 1618-1631.
    • (2010) Rheumatology (Oxford) , vol.49 , pp. 1618-1631
    • Wright, H.L.1    Moots, R.J.2    Bucknall, R.C.3
  • 94
    • 84902660702 scopus 로고    scopus 로고
    • Central adiponectin administration reveals new regulatory mechanisms of bone metabolism in mice
    • Wu, Y., Tu, Q., Valverde, P., et al. (2014). Central adiponectin administration reveals new regulatory mechanisms of bone metabolism in mice. Am. J. Physiol. Endocrinol. Metab. 306, E1418-E1430.
    • (2014) Am. J. Physiol. Endocrinol. Metab. , vol.306 , pp. E1418-E1430
    • Wu, Y.1    Tu, Q.2    Valverde, P.3
  • 95
  • 96
    • 0041302377 scopus 로고    scopus 로고
    • The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice
    • Xu, A., Wang, Y., Keshaw, H., et al. (2003). The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J. Clin. Invest. 112, 91-100.
    • (2003) J. Clin. Invest. , vol.112 , pp. 91-100
    • Xu, A.1    Wang, Y.2    Keshaw, H.3
  • 97
    • 28844494503 scopus 로고    scopus 로고
    • Adiponectin inhibits Toll-like receptor family-induced signaling
    • Yamaguchi, N., Argueta, J.G., Masuhiro, Y., et al. (2005). Adiponectin inhibits Toll-like receptor family-induced signaling. FEBS Lett. 579, 6821-6826.
    • (2005) FEBS Lett. , vol.579 , pp. 6821-6826
    • Yamaguchi, N.1    Argueta, J.G.2    Masuhiro, Y.3
  • 98
    • 38649123699 scopus 로고    scopus 로고
    • Adiponectin inhibits induction of TNF - A/RANKL-stimulated NFATc1 via the AMPK signaling
    • Yamaguchi, N., Kukita, T., Li, Y.J., et al. (2008). Adiponectin inhibits induction of TNF-a/RANKL-stimulated NFATc1 via the AMPK signaling. FEBS Lett. 582, 451-456.
    • (2008) FEBS Lett. , vol.582 , pp. 451-456
    • Yamaguchi, N.1    Kukita, T.2    Li, Y.J.3
  • 99
    • 84884233549 scopus 로고    scopus 로고
    • Adiponectin attenuateshuman eosinophil adhesion and chemotaxis: Implications in allergic inflammation
    • Yamamoto, R., Ueki, S., Moritoki, Y., et al. (2013). Adiponectin attenuateshuman eosinophil adhesion and chemotaxis: implications in allergic inflammation. J. Asthma 50, 828-835.
    • (2013) J. Asthma , vol.50 , pp. 828-835
    • Yamamoto, R.1    Ueki, S.2    Moritoki, Y.3
  • 100
    • 17944365228 scopus 로고    scopus 로고
    • The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
    • Yamauchi, T., Kamon, J., Waki, H., et al. (2001). The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat. Med. 7, 941-946.
    • (2001) Nat. Med. , vol.7 , pp. 941-946
    • Yamauchi, T.1    Kamon, J.2    Waki, H.3
  • 101
    • 0037494960 scopus 로고    scopus 로고
    • Cloning of adiponectin receptors that mediate antidiabetic metabolic effects
    • Yamauchi, T., Kamon, J., Ito, Y., et al. (2003). Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature 423, 762-769.
    • (2003) Nature , vol.423 , pp. 762-769
    • Yamauchi, T.1    Kamon, J.2    Ito, Y.3
  • 102
    • 33847733103 scopus 로고    scopus 로고
    • Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions
    • Yamauchi, T., Nio, Y., Maki, T., et al. (2007). Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions. Nat. Med. 13, 332-339.
    • (2007) Nat. Med. , vol.13 , pp. 332-339
    • Yamauchi, T.1    Nio, Y.2    Maki, T.3
  • 103
    • 85047687270 scopus 로고    scopus 로고
    • Adiponectin receptors: A review of their structure, function and how they work
    • Yamauchi, T., Iwabu, M., Okada-Iwabu, M., et al. (2014). Adiponectin receptors: a review of their structure, function and how they work. Best Pract. Res. Clin. Endocrinol. Metab. 28, 15-23.
    • (2014) Best Pract. Res. Clin. Endocrinol. Metab. , vol.28 , pp. 15-23
    • Yamauchi, T.1    Iwabu, M.2    Okada-Iwabu, M.3
  • 104
    • 0034284038 scopus 로고    scopus 로고
    • Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages
    • Yokota, T., Oritani, K., Takahashi, I., et al. (2000). Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages. Blood 96, 1723-1732.
    • (2000) Blood , vol.96 , pp. 1723-1732
    • Yokota, T.1    Oritani, K.2    Takahashi, I.3
  • 105
    • 77950290067 scopus 로고    scopus 로고
    • Adiponectin promotes endotoxin tolerance in macrophages by inducing IRAK-M expression
    • Zacharioudaki, V., Androulidaki, A., Arranz, A., et al. (2009). Adiponectin promotes endotoxin tolerance in macrophages by inducing IRAK-M expression. J. Immunol. 182, 6444-6451.
    • (2009) J. Immunol. , vol.182 , pp. 6444-6451
    • Zacharioudaki, V.1    Androulidaki, A.2    Arranz, A.3
  • 106
    • 69249147344 scopus 로고    scopus 로고
    • 2+ /calmodulin-dependent protein kinase kinase-dependent pathways
    • 2+ /calmodulin-dependent protein kinase kinase-dependent pathways. J. Biol. Chem. 284, 22426-22435.
    • (2009) J. Biol. Chem. , vol.284 , pp. 22426-22435
    • Zhou, L.1    Deepa, S.S.2    Etzler, J.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.