Adiponectin regulates bone mass via opposite central and peripheral mechanisms through foxo1

Cell Metabolism

Volumn 17, Issue 6, 2013, Pages 901-915

  Kajimura, Daisuke ^a   Lee, Ha Won ^a   Riley, Kyle J ^a   Arteaga Solis, Emilio ^a   Ferron, Mathieu ^a   Zhou, Bin ^b   Clarke, Christopher J ^c   Hannun, Yusuf A ^c   Depinho, Ronald A ^d   Guo, Edward X ^b   Mann, J John ^a   Karsenty, Gerard ^a  

^a Columbia University ^*  (United States)

^b Stony Brook University Cancer Center ^*  (United States)

^c Stony Brook Medicine   (United States)

^d UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; LEPTIN; OSTEOCALCIN; PHOSPHATIDYLINOSITOL 3 KINASE; TRANSCRIPTION FACTOR FKHR;

ADRENERGIC SYSTEM; ANIMAL CELL; APOPTOSIS; ARTICLE; BLOOD PRESSURE; BONE MASS; CELL FUNCTION; CELL PROLIFERATION; CONTROLLED STUDY; ENERGY EXPENDITURE; HUMAN; LOCUS CERULEUS; MALE; MOUSE; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SYMPATHETIC TONE;

ADIPONECTIN; ANIMALS; APOPTOSIS; BONE AND BONES; BONE DENSITY; CELL PROLIFERATION; ENERGY METABOLISM; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; LEPTIN; LOCUS COERULEUS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OSTEOBLASTS; OSTEOCALCIN; PHOSPHATIDYLINOSITOL 3-KINASES; SIGNAL TRANSDUCTION; SYMPATHETIC NERVOUS SYSTEM;

ANIMALIA;

EID: 84878783089     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2013.04.009     Document Type: Article

References (40)

1. B.M. Burgering, and G.J. Kops Cell cycle and death control: long live Forkheads Trends Biochem. Sci. 27 2002 352 360
2. M.S. Denzel, M.C. Scimia, P.M. Zumstein, K. Walsh, P. Ruiz-Lozano, and B. Ranscht T-cadherin is critical for adiponectin-mediated cardioprotection in mice J. Clin. Invest. 120 2010 4342 4352
3. P. Ducy, M. Amling, S. Takeda, M. Priemel, A.F. Schilling, F.T. Beil, J. Shen, C. Vinson, J.M. Rueger, and G. Karsenty Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass Cell 100 2000 197 207
4. F. Elefteriou, S. Takeda, K. Ebihara, J. Magre, N. Patano, C.A. Kim, Y. Ogawa, X. Liu, S.M. Ware, and W.J. Craigen Serum leptin level is a regulator of bone mass Proc. Natl. Acad. Sci. USA 101 2004 3258 3263
5. F. Elefteriou, J.D. Ahn, S. Takeda, M. Starbuck, X. Yang, X. Liu, H. Kondo, W.G. Richards, T.W. Bannon, and M. Noda Leptin regulation of bone resorption by the sympathetic nervous system and CART Nature 434 2005 514 520
6. J.A. Engelman Targeting PI3K signalling in cancer: opportunities, challenges and limitations Nat. Rev. Cancer 9 2009 550 562
7. J.C. Erickson, K.E. Clegg, and R.D. Palmiter Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y Nature 381 1996 415 421
8. J. Fan, J. Wang, A. Bensadoun, S.J. Lauer, Q. Dang, R.W. Mahley, and J.M. Taylor Overexpression of hepatic lipase in transgenic rabbits leads to a marked reduction of plasma high density lipoproteins and intermediate density lipoproteins Proc. Natl. Acad. Sci. USA 91 1994 8724 8728
9. M. Ferron, J. Wei, T. Yoshizawa, A. Del Fattore, R.A. DePinho, A. Teti, P. Ducy, and G. Karsenty Insulin signaling in osteoblasts integrates bone remodeling and energy metabolism Cell 142 2010 296 308
10. T. Finkel, and N.J. Holbrook Oxidants, oxidative stress and the biology of ageing Nature 408 2000 239 247
11. A.R. Guntur, and C.J. Rosen Bone as an endocrine organ Endocr. Pract. 18 2012 758 762
12. B.A. Henry, J.W. Goding, W.S. Alexander, A.J. Tilbrook, B.J. Canny, F. Dunshea, A. Rao, A. Mansell, and I.J. Clarke Central administration of leptin to ovariectomized ewes inhibits food intake without affecting the secretion of hormones from the pituitary gland: evidence for a dissociation of effects on appetite and neuroendocrine function Endocrinology 140 1999 1175 1182
13. W.L. Holland, R.A. Miller, Z.V. Wang, K. Sun, B.M. Barth, H.H. Bui, K.E. Davis, B.T. Bikman, N. Halberg, and J.M. Rutkowski Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin Nat. Med. 17 2011 55 63
14. C. Hug, J. Wang, N.S. Ahmad, J.S. Bogan, T.S. Tsao, and H.F. Lodish T-cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30/adiponectin Proc. Natl. Acad. Sci. USA 101 2004 10308 10313
15. T. Kadowaki, T. Yamauchi, N. Kubota, K. Hara, K. Ueki, and K. Tobe Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome J. Clin. Invest. 116 2006 1784 1792
16. G. Karsenty, and F. Oury Biology without walls: the novel endocrinology of bone Annu. Rev. Physiol. 74 2012 87 105
17. K. Kobayashi, M. Takahashi, N. Matsushita, J. Miyazaki, M. Koike, H. Yaginuma, N. Osumi, K. Kaibuchi, and K. Kobayashi Survival of developing motor neurons mediated by Rho GTPase signaling pathway through Rho-kinase J. Neurosci. 24 2004 3480 3488
18. C.M. Kusminski, P.G. McTernan, T. Schraw, K. Kos, J.P. O'Hare, R. Ahima, S. Kumar, and P.E. Scherer Adiponectin complexes in human cerebrospinal fluid: distinct complex distribution from serum Diabetologia 50 2007 634 642
19. D.L. Lacey, E. Timms, H.L. Tan, M.J. Kelley, C.R. Dunstan, T. Burgess, R. Elliott, A. Colombero, G. Elliott, and S. Scully Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation Cell 93 1998 165 176
20. N.K. Lee, H. Sowa, E. Hinoi, M. Ferron, J.D. Ahn, C. Confavreux, R. Dacquin, P.J. Mee, M.D. McKee, and D.Y. Jung Endocrine regulation of energy metabolism by the skeleton Cell 130 2007 456 469
21. E.S. Lein, M.J. Hawrylycz, N. Ao, M. Ayres, A. Bensinger, A. Bernard, A.F. Boe, M.S. Boguski, K.S. Brockway, and E.J. Byrnes Genome-wide atlas of gene expression in the adult mouse brain Nature 445 2007 168 176
22. K. Ma, A. Cabrero, P.K. Saha, H. Kojima, L. Li, B.H. Chang, A. Paul, and L. Chan Increased beta -oxidation but no insulin resistance or glucose intolerance in mice lacking adiponectin J. Biol. Chem. 277 2002 34658 34661
23. N. Maeda, I. Shimomura, K. Kishida, H. Nishizawa, M. Matsuda, H. Nagaretani, N. Furuyama, H. Kondo, M. Takahashi, and Y. Arita Diet-induced insulin resistance in mice lacking adiponectin/ACRP30 Nat. Med. 8 2002 731 737
24. C.A. McCulloch, M. Strugurescu, F. Hughes, A.H. Melcher, and J.E. Aubin Osteogenic progenitor cells in rat bone marrow stromal populations exhibit self-renewal in culture Blood 77 1991 1906 1911
25. K. Nonogaki New insights into sympathetic regulation of glucose and fat metabolism Diabetologia 43 2000 533 549
26. K. Oshima, A. Nampei, M. Matsuda, M. Iwaki, A. Fukuhara, J. Hashimoto, H. Yoshikawa, and I. Shimomura Adiponectin increases bone mass by suppressing osteoclast and activating osteoblast Biochem. Biophys. Res. Commun. 331 2005 520 526
27. Y. Qi, N. Takahashi, S.M. Hileman, H.R. Patel, A.H. Berg, U.B. Pajvani, P.E. Scherer, and R.S. Ahima Adiponectin acts in the brain to decrease body weight Nat. Med. 10 2004 524 529
28. M.T. Rached, A. Kode, L. Xu, Y. Yoshikawa, J.H. Paik, R.A. Depinho, and S. Kousteni FoxO1 is a positive regulator of bone formation by favoring protein synthesis and resistance to oxidative stress in osteoblasts Cell Metab. 11 2010 147 160
29. R.A. Rush, and L.B. Geffen Dopamine beta-hydroxylase in health and disease Crit. Rev. Clin. Lab. Sci. 12 1980 241 277
30. K. Sharma, S. Ramachandrarao, G. Qiu, H.K. Usui, Y. Zhu, S.R. Dunn, R. Ouedraogo, K. Hough, P. McCue, and L. Chan Adiponectin regulates albuminuria and podocyte function in mice J. Clin. Invest. 118 2008 1645 1656
31. Y. Shinoda, M. Yamaguchi, N. Ogata, T. Akune, N. Kubota, T. Yamauchi, Y. Terauchi, T. Kadowaki, Y. Takeuchi, and S. Fukumoto Regulation of bone formation by adiponectin through autocrine/paracrine and endocrine pathways J. Cell. Biochem. 99 2006 196 208
32. S. Takeda, F. Elefteriou, R. Levasseur, X. Liu, L. Zhao, K.L. Parker, D. Armstrong, P. Ducy, and G. Karsenty Leptin regulates bone formation via the sympathetic nervous system Cell 111 2002 305 317
33. Y. Takemura, N. Ouchi, R. Shibata, T. Aprahamian, M.T. Kirber, R.S. Summer, S. Kihara, and K. Walsh Adiponectin modulates inflammatory reactions via calreticulin receptor-dependent clearance of early apoptotic bodies J. Clin. Invest. 117 2007 375 386
34. C.M. Taniguchi, B. Emanuelli, and C.R. Kahn Critical nodes in signalling pathways: insights into insulin action Nat. Rev. Mol. Cell Biol. 7 2006 85 96
35. N. Tentolouris, S. Liatis, and N. Katsilambros Sympathetic system activity in obesity and metabolic syndrome Ann. N Y Acad. Sci. 1083 2006 129 152
36. S.A. Thomas, A.M. Matsumoto, and R.D. Palmiter Noradrenaline is essential for mouse fetal development Nature 374 1995 643 646
37. S. Vaira, C. Yang, A. McCoy, K. Keys, S. Xue, E.J. Weinstein, D.V. Novack, and X. Cui Creation and preliminary characterization of a leptin knockout rat Endocrinology 153 2012 5622 5628
38. J. Wu, P. Boström, L.M. Sparks, L. Ye, J.H. Choi, A.H. Giang, M. Khandekar, K.A. Virtanen, P. Nuutila, and G. Schaart Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human Cell 150 2012 366 376
39. T. Yamauchi, J. Kamon, Y. Minokoshi, Y. Ito, H. Waki, S. Uchida, S. Yamashita, M. Noda, S. Kita, and K. Ueki Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase Nat. Med. 8 2002 1288 1295
40. T. Yamauchi, J. Kamon, Y. Ito, A. Tsuchida, T. Yokomizo, S. Kita, T. Sugiyama, M. Miyagishi, K. Hara, and M. Tsunoda Cloning of adiponectin receptors that mediate antidiabetic metabolic effects Nature 423 2003 762 769