-
1
-
-
0002899044
-
Protection of adrenalectomized animals against bacterial intoxication by an extract of the adrenal cortex
-
Hartman FA, Scott WJ. Protection of adrenalectomized animals against bacterial intoxication by an extract of the adrenal cortex. J Exp Med (1932) 55:63-9. doi:10.1084/jem.55.1.63
-
(1932)
J Exp Med
, vol.55
, pp. 63-69
-
-
Hartman, F.A.1
Scott, W.J.2
-
2
-
-
37049226385
-
On the hormonal activity of a steroid compound
-
Selye H. On the hormonal activity of a steroid compound. Science (1941) 94:94. doi:10.1126/science.94.2430.94
-
(1941)
Science
, vol.94
, pp. 94
-
-
Selye, H.1
-
3
-
-
0023751736
-
Lipocortin and the mechanism of action of the glucocorticoids
-
Flower RJ. Lipocortin and the mechanism of action of the glucocorticoids. Br J Pharmacol (1988) 94:987-1015. doi:10.1111/j.1476-5381.1988.tb11614.x
-
(1988)
Br J Pharmacol
, vol.94
, pp. 987-1015
-
-
Flower, R.J.1
-
4
-
-
84960481425
-
Heroes in endocrinology: Nobel Prizes
-
de Herder WW. Heroes in endocrinology: Nobel Prizes. Endocr Connect (2014) 3:R94-104. doi:10.1530/EC-14-0070
-
(2014)
Endocr Connect
, vol.3
, pp. R94-R104
-
-
de Herder, W.W.1
-
5
-
-
0018755280
-
Anti-inflammatory steroids induce biosynthesis of a phospholipase A2 inhibitor which prevents prostaglandin generation
-
Flower RJ, Blackwell GJ. Anti-inflammatory steroids induce biosynthesis of a phospholipase A2 inhibitor which prevents prostaglandin generation. Nature (1979) 278:456-9. doi:10.1038/278456a0
-
(1979)
Nature
, vol.278
, pp. 456-459
-
-
Flower, R.J.1
Blackwell, G.J.2
-
6
-
-
0018713739
-
Involvement of glucocorticoid receptors in steroid-induced inhibition of prostaglandin secretion
-
Russo-Marie F, Paing M, Duval D. Involvement of glucocorticoid receptors in steroid-induced inhibition of prostaglandin secretion. J Biol Chem (1979) 254:8498-504
-
(1979)
J Biol Chem
, vol.254
, pp. 8498-8504
-
-
Russo-Marie, F.1
Paing, M.2
Duval, D.3
-
7
-
-
0018747884
-
The role of glucocorticoid receptor and gene expression in the anti-inflammatory action of dexamethasone
-
Tsurufuji S, Sugio K, Takemasa F. The role of glucocorticoid receptor and gene expression in the anti-inflammatory action of dexamethasone. Nature (1979) 280:408-10. doi:10.1038/280408a0
-
(1979)
Nature
, vol.280
, pp. 408-410
-
-
Tsurufuji, S.1
Sugio, K.2
Takemasa, F.3
-
8
-
-
84954054548
-
Historical overview of nuclear receptors
-
Gustafsson J-A. Historical overview of nuclear receptors. J Steroid Biochem Mol Biol (2015) 157:3-6. doi:10.1016/j.jsbmb.2015.03.004
-
(2015)
J Steroid Biochem Mol Biol
, vol.157
, pp. 3-6
-
-
Gustafsson, J.-A.1
-
9
-
-
0025150272
-
Mutual transrepression of Fos and the glucocorticoid receptor: involvement of a functional domain in Fos which is absent in FosB
-
Lucibello FC, Slater EP, Jooss KU, Beato M, Müller R. Mutual transrepression of Fos and the glucocorticoid receptor: involvement of a functional domain in Fos which is absent in FosB. EMBO J (1990) 9:2827-34
-
(1990)
EMBO J
, vol.9
, pp. 2827-2834
-
-
Lucibello, F.C.1
Slater, E.P.2
Jooss, K.U.3
Beato, M.4
Müller, R.5
-
10
-
-
0028107237
-
Physical association and functional antagonism between the p65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor
-
Ray A, Prefontaine KE. Physical association and functional antagonism between the p65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor. Proc Natl Acad Sci U S A (1994) 91:752-6. doi:10.1073/pnas.91.2.752
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 752-756
-
-
Ray, A.1
Prefontaine, K.E.2
-
11
-
-
0028831128
-
Characterization of mechanisms involved in transrepression of NF-kappa B by activated glucocorticoid receptors
-
Scheinman RI, Gualberto A, Jewell CM, Cidlowski JA, Baldwin AS. Characterization of mechanisms involved in transrepression of NF-kappa B by activated glucocorticoid receptors. Mol Cell Biol (1995) 15:943-53. doi:10.1128/MCB.15.2.943
-
(1995)
Mol Cell Biol
, vol.15
, pp. 943-953
-
-
Scheinman, R.I.1
Gualberto, A.2
Jewell, C.M.3
Cidlowski, J.A.4
Baldwin, A.S.5
-
12
-
-
84933673873
-
Selective glucocorticoid receptor modulation: new directions with non-steroidal scaffolds
-
Sundahl N, Bridelance J, Libert C, De Bosscher K, Beck IM. Selective glucocorticoid receptor modulation: new directions with non-steroidal scaffolds. Pharmacol Ther (2015) 152:28-41. doi:10.1016/j.pharmthera.2015.05.001
-
(2015)
Pharmacol Ther
, vol.152
, pp. 28-41
-
-
Sundahl, N.1
Bridelance, J.2
Libert, C.3
De Bosscher, K.4
Beck, I.M.5
-
13
-
-
34547736572
-
Crosstalk among Jak-STAT, Toll-like receptor, and ITAM-dependent pathways in macrophage activation
-
Hu X, Chen J, Wang L, Ivashkiv LB. Crosstalk among Jak-STAT, Toll-like receptor, and ITAM-dependent pathways in macrophage activation. J Leukoc Biol (2007) 82:237-43. doi:10.1189/jlb.1206763
-
(2007)
J Leukoc Biol
, vol.82
, pp. 237-243
-
-
Hu, X.1
Chen, J.2
Wang, L.3
Ivashkiv, L.B.4
-
14
-
-
84893075305
-
Regulation of type I interferon responses
-
Ivashkiv LB, Donlin LT. Regulation of type I interferon responses. Nat Rev Immunol (2014) 14:36-49. doi:10.1038/nri3581
-
(2014)
Nat Rev Immunol
, vol.14
, pp. 36-49
-
-
Ivashkiv, L.B.1
Donlin, L.T.2
-
15
-
-
80051987703
-
Crosstalk in NF-κB signaling pathways
-
Oeckinghaus A, Hayden MS, Ghosh S. Crosstalk in NF-κB signaling pathways. Nat Immunol (2011) 12:695-708. doi:10.1038/ni.2065
-
(2011)
Nat Immunol
, vol.12
, pp. 695-708
-
-
Oeckinghaus, A.1
Hayden, M.S.2
Ghosh, S.3
-
16
-
-
34547108380
-
JAK-STAT signaling: from interferons to cytokines
-
Schindler C, Levy DE, Decker T. JAK-STAT signaling: from interferons to cytokines. J Biol Chem (2007) 282:20059-63. doi:10.1074/jbc. R700016200
-
(2007)
J Biol Chem
, vol.282
, pp. 20059-20063
-
-
Schindler, C.1
Levy, D.E.2
Decker, T.3
-
17
-
-
0032467785
-
Brain corticosteroid receptor balance in health and disease
-
De Kloet ER, Vreugdenhil E, Oitzl MS, Joels M. Brain corticosteroid receptor balance in health and disease. Endocr Rev (1998) 19:269-301. doi:10.1210/edrv.19.3.0331
-
(1998)
Endocr Rev
, vol.19
, pp. 269-301
-
-
De Kloet, E.R.1
Vreugdenhil, E.2
Oitzl, M.S.3
Joels, M.4
-
18
-
-
71849112377
-
The human glucocorticoid receptor: molecular basis of biologic function
-
Nicolaides NC, Galata Z, Kino T, Chrousos GP, Charmandari E. The human glucocorticoid receptor: molecular basis of biologic function. Steroids (2010) 75:1-12. doi:10.1016/j.steroids.2009.09.002
-
(2010)
Steroids
, vol.75
, pp. 1-12
-
-
Nicolaides, N.C.1
Galata, Z.2
Kino, T.3
Chrousos, G.P.4
Charmandari, E.5
-
19
-
-
33745090483
-
Glucocorticoid receptor isoforms generate transcription specificity
-
Lu NZ, Cidlowski JA. Glucocorticoid receptor isoforms generate transcription specificity. Trends Cell Biol (2006) 16:301-7. doi:10.1016/j.tcb.2006.04.005
-
(2006)
Trends Cell Biol
, vol.16
, pp. 301-307
-
-
Lu, N.Z.1
Cidlowski, J.A.2
-
20
-
-
33751000477
-
Multiple glucocorticoid receptor isoforms and mechanisms of post-translational modification
-
Duma D, Jewell CM, Cidlowski JA. Multiple glucocorticoid receptor isoforms and mechanisms of post-translational modification. J Steroid Biochem Mol Biol (2006) 102:11-21. doi:10.1016/j.jsbmb.2006.09.009
-
(2006)
J Steroid Biochem Mol Biol
, vol.102
, pp. 11-21
-
-
Duma, D.1
Jewell, C.M.2
Cidlowski, J.A.3
-
21
-
-
18144399332
-
The human glucocorticoid receptor: one gene, multiple proteins and diverse responses
-
Zhou J, Cidlowski JA. The human glucocorticoid receptor: one gene, multiple proteins and diverse responses. Steroids (2005) 70:407-17. doi:10.1016/j.steroids.2005.02.006
-
(2005)
Steroids
, vol.70
, pp. 407-417
-
-
Zhou, J.1
Cidlowski, J.A.2
-
22
-
-
0042889568
-
The roles of protein-protein interactions and protein methylation in transcriptional activation by nuclear receptors and their coactivators
-
Stallcup MR, Kim JH, Teyssier C, Lee Y-H, Ma H, Chen D. The roles of protein-protein interactions and protein methylation in transcriptional activation by nuclear receptors and their coactivators. J Steroid Biochem Mol Biol (2003) 85:139-45. doi:10.1016/S0960-0760(03)00222-X
-
(2003)
J Steroid Biochem Mol Biol
, vol.85
, pp. 139-145
-
-
Stallcup, M.R.1
Kim, J.H.2
Teyssier, C.3
Lee, Y.-H.4
Ma, H.5
Chen, D.6
-
23
-
-
78649846415
-
Steroid receptor coactivator (SRC) family: masters of systems biology
-
York B, O'Malley BW. Steroid receptor coactivator (SRC) family: masters of systems biology. J Biol Chem (2010) 285:38743-50. doi:10.1074/jbc. R110.193367
-
(2010)
J Biol Chem
, vol.285
, pp. 38743-38750
-
-
York, B.1
O'Malley, B.W.2
-
24
-
-
0037064150
-
Coordinate regulation of transcription and splicing by steroid receptor coregulators
-
Auboeuf D, Hönig A, Berget SM, O'Malley BW. Coordinate regulation of transcription and splicing by steroid receptor coregulators. Science (2002) 298:416-9. doi:10.1126/science.1073734
-
(2002)
Science
, vol.298
, pp. 416-419
-
-
Auboeuf, D.1
Hönig, A.2
Berget, S.M.3
O'Malley, B.W.4
-
25
-
-
0037154974
-
Combinatorial control of gene expression by nuclear receptors and coregulators
-
McKenna NJ, O'Malley BW. Combinatorial control of gene expression by nuclear receptors and coregulators. Cell (2002) 108:465-74. doi:10.1016/S0092-8674(02)00641-4
-
(2002)
Cell
, vol.108
, pp. 465-474
-
-
McKenna, N.J.1
O'Malley, B.W.2
-
26
-
-
0033305547
-
Nuclear receptor coregulators: cellular and molecular biology
-
McKenna NJ, Lanz RB, O'Malley BW. Nuclear receptor coregulators: cellular and molecular biology. Endocr Rev (1999) 20:321-44. doi:10.1210/edrv.20.3.0366
-
(1999)
Endocr Rev
, vol.20
, pp. 321-344
-
-
McKenna, N.J.1
Lanz, R.B.2
O'Malley, B.W.3
-
27
-
-
0033051731
-
Nuclear receptor coactivators: multiple enzymes, multiple complexes, multiple functions
-
McKenna NJ, Xu J, Nawaz Z, Tsai SY, Tsai MJ, O'Malley BW. Nuclear receptor coactivators: multiple enzymes, multiple complexes, multiple functions. J Steroid Biochem Mol Biol (1999) 69:3-12. doi:10.1016/S0960-0760(98)00144-7
-
(1999)
J Steroid Biochem Mol Biol
, vol.69
, pp. 3-12
-
-
McKenna, N.J.1
Xu, J.2
Nawaz, Z.3
Tsai, S.Y.4
Tsai, M.J.5
O'Malley, B.W.6
-
28
-
-
0025015647
-
Antitumor promotion and antiinflammation: down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone
-
Jonat C, Rahmsdorf HJ, Park KK, Cato AC, Gebel S, Ponta H, et al. Antitumor promotion and antiinflammation: down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone. Cell (1990) 62:1189-204. doi:10.1016/0092-8674(90)90395-U
-
(1990)
Cell
, vol.62
, pp. 1189-1204
-
-
Jonat, C.1
Rahmsdorf, H.J.2
Park, K.K.3
Cato, A.C.4
Gebel, S.5
Ponta, H.6
-
29
-
-
0036226710
-
Tissue-specific glucocorticoid resistance-hypersensitivity syndromes: multifactorial states of clinical importance
-
Kino T, Chrousos GP. Tissue-specific glucocorticoid resistance-hypersensitivity syndromes: multifactorial states of clinical importance. J Allergy Clin Immunol (2002) 109:609-13. doi:10.1067/mai.2002.123708
-
(2002)
J Allergy Clin Immunol
, vol.109
, pp. 609-613
-
-
Kino, T.1
Chrousos, G.P.2
-
30
-
-
0031865468
-
Transcriptional cross-talk, the second mode of steroid hormone receptor action
-
Göttlicher M, Heck S, Herrlich P. Transcriptional cross-talk, the second mode of steroid hormone receptor action. J Mol Med (Berl) (1998) 76:480-9. doi:10.1007/s001090050242
-
(1998)
J Mol Med (Berl)
, vol.76
, pp. 480-489
-
-
Göttlicher, M.1
Heck, S.2
Herrlich, P.3
-
31
-
-
79953871100
-
Widespread negative response elements mediate direct repression by agonist-liganded glucocorticoid receptor
-
Surjit M, Ganti KP, Mukherji A, Ye T, Hua G, Metzger D, et al. Widespread negative response elements mediate direct repression by agonist-liganded glucocorticoid receptor. Cell (2011) 145:224-41. doi:10.1016/j.cell.2011.03.027
-
(2011)
Cell
, vol.145
, pp. 224-241
-
-
Surjit, M.1
Ganti, K.P.2
Mukherji, A.3
Ye, T.4
Hua, G.5
Metzger, D.6
-
32
-
-
0025081214
-
Transcription factor interactions: selectors of positive or negative regulation from a single DNA element
-
Diamond MI, Miner JN, Yoshinaga SK, Yamamoto KR. Transcription factor interactions: selectors of positive or negative regulation from a single DNA element. Science (1990) 249:1266-72. doi:10.1126/science.2119054
-
(1990)
Science
, vol.249
, pp. 1266-1272
-
-
Diamond, M.I.1
Miner, J.N.2
Yoshinaga, S.K.3
Yamamoto, K.R.4
-
33
-
-
0029178117
-
Role of the composite glucocorticoid response element in proliferin gene expression
-
Hoeppner MA, Mordacq JC, Linzer DI. Role of the composite glucocorticoid response element in proliferin gene expression. Gene Expr (1995) 5:133-41
-
(1995)
Gene Expr
, vol.5
, pp. 133-141
-
-
Hoeppner, M.A.1
Mordacq, J.C.2
Linzer, D.I.3
-
34
-
-
3042788350
-
Modulation of glucocorticoid receptor function via phosphorylation
-
Ismaili N, Garabedian MJ. Modulation of glucocorticoid receptor function via phosphorylation. Ann N Y Acad Sci (2004) 1024:86-101. doi:10.1196/annals.1321.007
-
(2004)
Ann N Y Acad Sci
, vol.1024
, pp. 86-101
-
-
Ismaili, N.1
Garabedian, M.J.2
-
35
-
-
0027516721
-
Kinetics of glucocorticoid receptor phosphorylation in intact cells. Evidence for hormone-induced hyperphosphorylation after activation and recycling of hyperphosphorylated receptors
-
Orti E, Hu LM, Munck A. Kinetics of glucocorticoid receptor phosphorylation in intact cells. Evidence for hormone-induced hyperphosphorylation after activation and recycling of hyperphosphorylated receptors. J Biol Chem (1993) 268:7779-84
-
(1993)
J Biol Chem
, vol.268
, pp. 7779-7784
-
-
Orti, E.1
Hu, L.M.2
Munck, A.3
-
36
-
-
31344446119
-
Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression
-
Ito K, Yamamura S, Essilfie-Quaye S, Cosio B, Ito M, Barnes PJ, et al. Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression. J Exp Med (2006) 203:7-13. doi:10.1084/jem.20050466
-
(2006)
J Exp Med
, vol.203
, pp. 7-13
-
-
Ito, K.1
Yamamura, S.2
Essilfie-Quaye, S.3
Cosio, B.4
Ito, M.5
Barnes, P.J.6
-
37
-
-
34547872354
-
Glucocorticoid receptor action in beneficial and side effects of steroid therapy: lessons from conditional knockout mice
-
Kleiman A, Tuckermann JP. Glucocorticoid receptor action in beneficial and side effects of steroid therapy: lessons from conditional knockout mice. Mol Cell Endocrinol (2007) 275:98-108. doi:10.1016/j.mce.2007.05.009
-
(2007)
Mol Cell Endocrinol
, vol.275
, pp. 98-108
-
-
Kleiman, A.1
Tuckermann, J.P.2
-
38
-
-
27644492383
-
A fully dissociated compound of plant origin for inflammatory gene repression
-
De Bosscher K, Vanden Berghe W, Beck IM, Van Molle W, Hennuyer N, Hapgood J, et al. A fully dissociated compound of plant origin for inflammatory gene repression. Proc Natl Acad Sci U S A (2005) 102:15827-32. doi:10.1073/pnas.0505554102
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 15827-15832
-
-
De Bosscher, K.1
Vanden Berghe, W.2
Beck, I.M.3
Van Molle, W.4
Hennuyer, N.5
Hapgood, J.6
-
39
-
-
34748920671
-
Separating transrepression and transactivation: a distressing divorce for the glucocorticoid receptor?
-
Newton R, Holden NS. Separating transrepression and transactivation: a distressing divorce for the glucocorticoid receptor? Mol Pharmacol (2007) 72:799-809. doi:10.1124/mol.107.038794
-
(2007)
Mol Pharmacol
, vol.72
, pp. 799-809
-
-
Newton, R.1
Holden, N.S.2
-
40
-
-
84922771228
-
An analysis of glucocorticoid receptor-mediated gene expression in BEAS-2B human airway epithelial cells identifies distinct, ligand-directed, transcription profiles with implications for asthma therapeutics
-
Joshi T, Johnson M, Newton R, Giembycz M. An analysis of glucocorticoid receptor-mediated gene expression in BEAS-2B human airway epithelial cells identifies distinct, ligand-directed, transcription profiles with implications for asthma therapeutics. Br J Pharmacol (2015) 172:1360-78. doi:10.1111/bph.13014
-
(2015)
Br J Pharmacol
, vol.172
, pp. 1360-1378
-
-
Joshi, T.1
Johnson, M.2
Newton, R.3
Giembycz, M.4
-
41
-
-
84870330189
-
Mechanisms of the anti-inflammatory effects of glucocorticoids: genomic and nongenomic interference with MAPK signaling pathways
-
Ayroldi E, Cannarile L, Migliorati G, Nocentini G, Delfino DV, Riccardi C. Mechanisms of the anti-inflammatory effects of glucocorticoids: genomic and nongenomic interference with MAPK signaling pathways. FASEB J (2012) 26:4805-20. doi:10.1096/fj.12-216382
-
(2012)
FASEB J
, vol.26
, pp. 4805-4820
-
-
Ayroldi, E.1
Cannarile, L.2
Migliorati, G.3
Nocentini, G.4
Delfino, D.V.5
Riccardi, C.6
-
42
-
-
82455212462
-
Nongenomic glucocorticoid signaling: new targets for immunosuppressive therapy?
-
Schoneveld JLM, Fritsch-Stork RD, Bijlsma JWJ. Nongenomic glucocorticoid signaling: new targets for immunosuppressive therapy? Arthritis Rheum (2011) 63:3665-7. doi:10.1002/art.30635
-
(2011)
Arthritis Rheum
, vol.63
, pp. 3665-3667
-
-
Schoneveld, J.L.M.1
Fritsch-Stork, R.D.2
Bijlsma, J.W.J.3
-
43
-
-
84883769810
-
Glucocorticoid receptor signaling in health and disease
-
Kadmiel M, Cidlowski JA. Glucocorticoid receptor signaling in health and disease. Trends Pharmacol Sci (2013) 34:518-30. doi:10.1016/j.tips.2013.07.003
-
(2013)
Trends Pharmacol Sci
, vol.34
, pp. 518-530
-
-
Kadmiel, M.1
Cidlowski, J.A.2
-
44
-
-
84932119466
-
Dual-specificity phosphatase 1 and tristetraprolin cooperate to regulate macrophage responses to lipopolysaccharide
-
Smallie T, Ross EA, Ammit AJ, Cunliffe HE, Tang T, Rosner DR, et al. Dual-specificity phosphatase 1 and tristetraprolin cooperate to regulate macrophage responses to lipopolysaccharide. J Immunol (2015) 195:277-88. doi:10.4049/jimmunol.1402830
-
(2015)
J Immunol
, vol.195
, pp. 277-288
-
-
Smallie, T.1
Ross, E.A.2
Ammit, A.J.3
Cunliffe, H.E.4
Tang, T.5
Rosner, D.R.6
-
45
-
-
84949754523
-
GILZ as a mediator of the anti-inflammatory effects of glucocorticoids
-
Ronchetti S, Migliorati G, Riccardi C. GILZ as a mediator of the anti-inflammatory effects of glucocorticoids. Front Endocrinol (2015) 6:170. doi:10.3389/fendo.2015.00170
-
(2015)
Front Endocrinol
, vol.6
, pp. 170
-
-
Ronchetti, S.1
Migliorati, G.2
Riccardi, C.3
-
46
-
-
84872263381
-
Insights into negative regulation by the glucocorticoid receptor from genome-wide profiling of inflammatory cistromes
-
Uhlenhaut NH, Barish GD, Yu RT, Downes M, Karunasiri M, Liddle C, et al. Insights into negative regulation by the glucocorticoid receptor from genome-wide profiling of inflammatory cistromes. Mol Cell (2013) 49:158-71. doi:10.1016/j.molcel.2012.10.013
-
(2013)
Mol Cell
, vol.49
, pp. 158-171
-
-
Uhlenhaut, N.H.1
Barish, G.D.2
Yu, R.T.3
Downes, M.4
Karunasiri, M.5
Liddle, C.6
-
47
-
-
84884535413
-
Nuclear receptors in inflammation control: repression by GR and beyond
-
Chinenov Y, Gupte R, Rogatsky I. Nuclear receptors in inflammation control: repression by GR and beyond. Mol Cell Endocrinol (2013) 380:55-64. doi:10.1016/j.mce.2013.04.006
-
(2013)
Mol Cell Endocrinol
, vol.380
, pp. 55-64
-
-
Chinenov, Y.1
Gupte, R.2
Rogatsky, I.3
-
48
-
-
77951602823
-
Nuclear receptor transrepression pathways that regulate inflammation in macrophages and T cells
-
Glass CK, Saijo K. Nuclear receptor transrepression pathways that regulate inflammation in macrophages and T cells. Nat Rev Immunol (2010) 10:365-76. doi:10.1038/nri2748
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 365-376
-
-
Glass, C.K.1
Saijo, K.2
-
49
-
-
84923104586
-
Glucocorticoids suppress inflammation via the upregulation of negative regulator IRAK-M
-
Miyata M, Lee J-Y, Susuki-Miyata S, Wang WY, Xu H, Kai H, et al. Glucocorticoids suppress inflammation via the upregulation of negative regulator IRAK-M. Nat Commun (2015) 6:6062. doi:10.1038/ncomms7062
-
(2015)
Nat Commun
, vol.6
, pp. 6062
-
-
Miyata, M.1
Lee, J.-Y.2
Susuki-Miyata, S.3
Wang, W.Y.4
Xu, H.5
Kai, H.6
-
50
-
-
47049117420
-
Altered subcellular distribution of MSK1 induced by glucocorticoids contributes to NF-kappaB inhibition
-
Beck IM, Vanden Berghe W, Vermeulen L, Bougarne N, Vander Cruyssen B, Haegeman G, et al. Altered subcellular distribution of MSK1 induced by glucocorticoids contributes to NF-kappaB inhibition. EMBO J (2008) 27:1682-93. doi:10.1038/emboj.2008.95
-
(2008)
EMBO J
, vol.27
, pp. 1682-1693
-
-
Beck, I.M.1
Vanden Berghe, W.2
Vermeulen, L.3
Bougarne, N.4
Vander Cruyssen, B.5
Haegeman, G.6
-
51
-
-
58149511995
-
GRIP1-associated SET-domain methyltransferase in glucocorticoid receptor target gene expression
-
Chinenov Y, Sacta MA, Cruz AR, Rogatsky I. GRIP1-associated SET-domain methyltransferase in glucocorticoid receptor target gene expression. Proc Natl Acad Sci U S A (2008) 105:20185-90. doi:10.1073/pnas.0810863105
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 20185-20190
-
-
Chinenov, Y.1
Sacta, M.A.2
Cruz, A.R.3
Rogatsky, I.4
-
52
-
-
77956703571
-
The type I interferon signaling pathway is a target for glucocorticoid inhibition
-
Flammer JR, Dobrovolna J, Kennedy MA, Chinenov Y, Glass CK, Ivashkiv LB, et al. The type I interferon signaling pathway is a target for glucocorticoid inhibition. Mol Cell Biol (2010) 30:4564-74. doi:10.1128/MCB.00146-10
-
(2010)
Mol Cell Biol
, vol.30
, pp. 4564-4574
-
-
Flammer, J.R.1
Dobrovolna, J.2
Kennedy, M.A.3
Chinenov, Y.4
Glass, C.K.5
Ivashkiv, L.B.6
-
53
-
-
30444456366
-
The GRIP1:IRF3 interaction as a target for glucocorticoid receptor-mediated immunosuppression
-
Reily MM, Pantoja C, Hu X, Chinenov Y, Rogatsky I. The GRIP1:IRF3 interaction as a target for glucocorticoid receptor-mediated immunosuppression. EMBO J (2006) 25:108-17. doi:10.1038/sj.emboj.7600919
-
(2006)
EMBO J
, vol.25
, pp. 108-117
-
-
Reily, M.M.1
Pantoja, C.2
Hu, X.3
Chinenov, Y.4
Rogatsky, I.5
-
54
-
-
84872316647
-
Glucocorticoid repression of inflammatory gene expression shows differential responsiveness by transactivation-and transrepression-dependent mechanisms
-
King EM, Chivers JE, Rider CF, Minnich A, Giembycz MA, Newton R. Glucocorticoid repression of inflammatory gene expression shows differential responsiveness by transactivation-and transrepression-dependent mechanisms. PLoS One (2013) 8:e53936. doi:10.1371/journal.pone.0053936
-
(2013)
PLoS One
, vol.8
-
-
King, E.M.1
Chivers, J.E.2
Rider, C.F.3
Minnich, A.4
Giembycz, M.A.5
Newton, R.6
-
55
-
-
84929492994
-
Differential cytokine profiles upon comparing selective versus classic glucocorticoid receptor modulation in human peripheral blood mononuclear cells and inferior turbinate tissue
-
Beck IM, Van Crombruggen K, Holtappels G, Daubeuf F, Frossard N, Bachert C, et al. Differential cytokine profiles upon comparing selective versus classic glucocorticoid receptor modulation in human peripheral blood mononuclear cells and inferior turbinate tissue. PLoS One (2015) 10:e0123068. doi:10.1371/journal.pone.0123068
-
(2015)
PLoS One
, vol.10
-
-
Beck, I.M.1
Van Crombruggen, K.2
Holtappels, G.3
Daubeuf, F.4
Frossard, N.5
Bachert, C.6
-
56
-
-
0347719371
-
Dissociation of transactivation from transrepression by a selective glucocorticoid receptor agonist leads to separation of therapeutic effects from side effects
-
Schäcke H, Schottelius A, Döcke W-D, Strehlke P, Jaroch S, Schmees N, et al. Dissociation of transactivation from transrepression by a selective glucocorticoid receptor agonist leads to separation of therapeutic effects from side effects. Proc Natl Acad Sci U S A (2004) 101:227-32. doi:10.1073/pnas.0300372101
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 227-232
-
-
Schäcke, H.1
Schottelius, A.2
Döcke, W.-D.3
Strehlke, P.4
Jaroch, S.5
Schmees, N.6
-
57
-
-
84869055083
-
Org 214007-0: a novel non-steroidal selective glucocorticoid receptor modulator with full anti-inflammatory properties and improved therapeutic index
-
van Lierop MJC, Alkema W, Laskewitz AJ, Dijkema R, van der Maaden HM, Smit MJ, et al. Org 214007-0: a novel non-steroidal selective glucocorticoid receptor modulator with full anti-inflammatory properties and improved therapeutic index. PLoS One (2012) 7:e48385. doi:10.1371/journal.pone.0048385
-
(2012)
PLoS One
, vol.7
-
-
van Lierop, M.J.C.1
Alkema, W.2
Laskewitz, A.J.3
Dijkema, R.4
van der Maaden, H.M.5
Smit, M.J.6
-
58
-
-
0034454682
-
How do glucocorticoids influence stress responses?. Integrating permissive, suppressive, stimulatory, and preparative actions
-
Sapolsky RM, Romero LM, Munck AU. How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions. Endocr Rev (2000) 21:55-89. doi:10.1210/er.21.1.55
-
(2000)
Endocr Rev
, vol.21
, pp. 55-89
-
-
Sapolsky, R.M.1
Romero, L.M.2
Munck, A.U.3
-
59
-
-
55849129973
-
Genes involved in the balance between neuronal survival and death during inflammation
-
Glezer I, Chernomoretz A, David S, Plante MM, Rivest S. Genes involved in the balance between neuronal survival and death during inflammation. PLoS One (2007) 2:e310. doi:10.1371/journal.pone.0000310
-
(2007)
PLoS One
, vol.2
-
-
Glezer, I.1
Chernomoretz, A.2
David, S.3
Plante, M.M.4
Rivest, S.5
-
60
-
-
55449093226
-
Regulatory network analyses reveal genome-wide potentiation of LIF signaling by glucocorticoids and define an innate cell defense response
-
Langlais D, Couture C, Balsalobre A, Drouin J. Regulatory network analyses reveal genome-wide potentiation of LIF signaling by glucocorticoids and define an innate cell defense response. PLoS Genet (2008) 4:e1000224. doi:10.1371/journal.pgen.1000224
-
(2008)
PLoS Genet
, vol.4
-
-
Langlais, D.1
Couture, C.2
Balsalobre, A.3
Drouin, J.4
-
61
-
-
84864383684
-
Proinflammatory actions of glucocorticoids: glucocorticoids and TNFa coregulate gene expression in vitro and in vivo
-
Lannan EA, Galliher-Beckley AJ, Scoltock AB, Cidlowski JA. Proinflammatory actions of glucocorticoids: glucocorticoids and TNFa coregulate gene expression in vitro and in vivo. Endocrinology (2012) 153:3701-12. doi:10.1210/en.2012-1020
-
(2012)
Endocrinology
, vol.153
, pp. 3701-3712
-
-
Lannan, E.A.1
Galliher-Beckley, A.J.2
Scoltock, A.B.3
Cidlowski, J.A.4
-
62
-
-
33745385110
-
Effects of dexamethazone on LPS-induced activationand migration of mouse dendritic cells revealed by a genome-wide transcriptional analysis
-
Vizzardelli C, Pavelka N, Luchini A, Zanoni I, Bendickson L, Pelizzola M, et al. Effects of dexamethazone on LPS-induced activationand migration of mouse dendritic cells revealed by a genome-wide transcriptional analysis. Eur J Immunol (2006) 36:1504-15. doi:10.1002/eji.200535488
-
(2006)
Eur J Immunol
, vol.36
, pp. 1504-1515
-
-
Vizzardelli, C.1
Pavelka, N.2
Luchini, A.3
Zanoni, I.4
Bendickson, L.5
Pelizzola, M.6
-
63
-
-
84944737090
-
Glucocorticoid augments lipopolysaccharide-induced activation of the IkappaBzeta-dependent genes encoding the anti-microbial glycoproteins lipocalin 2 and pentraxin 3
-
Yamazaki S, Akira S, Sumimoto H. Glucocorticoid augments lipopolysaccharide-induced activation of the IkappaBzeta-dependent genes encoding the anti-microbial glycoproteins lipocalin 2 and pentraxin 3. J Biochem (2015) 157:399-410. doi:10.1093/jb/mvu086
-
(2015)
J Biochem
, vol.157
, pp. 399-410
-
-
Yamazaki, S.1
Akira, S.2
Sumimoto, H.3
-
64
-
-
0003737303
-
-
Oxford: Oxford University Press
-
Smith AD, Datta SP, Smith GH, Campbell PN, Bentley R, McKenzie H, et al. Oxford Dictionary of Biochemistry and Molecular Biology. Oxford: Oxford University Press (1997)
-
(1997)
Oxford Dictionary of Biochemistry and Molecular Biology
-
-
Smith, A.D.1
Datta, S.P.2
Smith, G.H.3
Campbell, P.N.4
Bentley, R.5
McKenzie, H.6
-
65
-
-
0033545342
-
Acute-phase proteins and other systemic responses to inflammation
-
Gabay C, Kushner I. Acute-phase proteins and other systemic responses to inflammation. N Engl J Med (1999) 340:448-54. doi:10.1056/NEJM199902113400607
-
(1999)
N Engl J Med
, vol.340
, pp. 448-454
-
-
Gabay, C.1
Kushner, I.2
-
66
-
-
84874615861
-
Secreted protein lipocalin-2 promotes microglial M1 polarization
-
Jang E, Lee S, Kim JH, Kim JH, Seo JW, Lee WH, et al. Secreted protein lipocalin-2 promotes microglial M1 polarization. FASEB J (2013) 27:1176-90. doi:10.1096/fj.12-222257
-
(2013)
FASEB J
, vol.27
, pp. 1176-1190
-
-
Jang, E.1
Lee, S.2
Kim, J.H.3
Kim, J.H.4
Seo, J.W.5
Lee, W.H.6
-
67
-
-
84881232123
-
Lipocalin 2 deactivates macrophages and worsens pneumococcal pneumonia outcomes
-
Warszawska JM, Gawish R, Sharif O, Sigel S, Doninger B, Lakovits K, et al. Lipocalin 2 deactivates macrophages and worsens pneumococcal pneumonia outcomes. J Clin Invest (2013) 123:3363-72. doi:10.1172/Jci67911
-
(2013)
J Clin Invest
, vol.123
, pp. 3363-3372
-
-
Warszawska, J.M.1
Gawish, R.2
Sharif, O.3
Sigel, S.4
Doninger, B.5
Lakovits, K.6
-
68
-
-
44649173850
-
The role of lipocalin 2 in the regulation of inflammation in adipocytes and macrophages
-
Zhang J, Wu Y, Zhang Y, Leroith D, Bernlohr DA, Chen X. The role of lipocalin 2 in the regulation of inflammation in adipocytes and macrophages. Mol Endocrinol (2008) 22:1416-26. doi:10.1210/me.2007-0420
-
(2008)
Mol Endocrinol
, vol.22
, pp. 1416-1426
-
-
Zhang, J.1
Wu, Y.2
Zhang, Y.3
Leroith, D.4
Bernlohr, D.A.5
Chen, X.6
-
69
-
-
84941740681
-
Biological actions of pentraxins
-
Vilahur G, Badimon L. Biological actions of pentraxins. Vascul Pharmacol (2015) 73:38-44. doi:10.1016/j.vph.2015.05.001
-
(2015)
Vascul Pharmacol
, vol.73
, pp. 38-44
-
-
Vilahur, G.1
Badimon, L.2
-
70
-
-
77953613542
-
Oncostatin M is a novel glucocorticoid-dependent neuroinflammatory factor that enhances oligodendrocyte precursor cell activity in demyelinated sites
-
Glezer I, Rivest S. Oncostatin M is a novel glucocorticoid-dependent neuroinflammatory factor that enhances oligodendrocyte precursor cell activity in demyelinated sites. Brain Behav Immun (2010) 24:695-704. doi:10.1016/j.bbi.2010.01.005
-
(2010)
Brain Behav Immun
, vol.24
, pp. 695-704
-
-
Glezer, I.1
Rivest, S.2
-
71
-
-
84900821938
-
Onostatin M acting via OSMR, augments the actions of IL-1 and TNF in synovial fibroblasts
-
Le GoffB, Singbrant S, Tonkin BA, Martin TJ, Romas E, Sims NA, et al. Onostatin M acting via OSMR, augments the actions of IL-1 and TNF in synovial fibroblasts. Cytokine (2014) 68:101-9. doi:10.1016/j.cyto.2014.04.001
-
(2014)
Cytokine
, vol.68
, pp. 101-109
-
-
Le Goff, B.1
Singbrant, S.2
Tonkin, B.A.3
Martin, T.J.4
Romas, E.5
Sims, N.A.6
-
72
-
-
79959851491
-
Minireview: glucocorticoids in autoimmunity: unexpected targets and mechanisms
-
Flammer JR, Rogatsky I. Minireview: glucocorticoids in autoimmunity: unexpected targets and mechanisms. Mol Endocrinol (2011) 25:1075-86. doi:10.1210/me.2011-0068
-
(2011)
Mol Endocrinol
, vol.25
, pp. 1075-1086
-
-
Flammer, J.R.1
Rogatsky, I.2
-
73
-
-
84875237427
-
The five Rs of glucocorticoid action during inflammation: ready, reinforce, repress, resolve, and restore
-
Busillo JM, Cidlowski JA. The five Rs of glucocorticoid action during inflammation: ready, reinforce, repress, resolve, and restore. Trends Endocrinol Metab (2013) 24:109-19. doi:10.1016/j.tem.2012.11.005
-
(2013)
Trends Endocrinol Metab
, vol.24
, pp. 109-119
-
-
Busillo, J.M.1
Cidlowski, J.A.2
-
74
-
-
34547670265
-
Glucocorticoids exert opposing effects on macrophage function dependent on their concentration
-
Lim H-Y, Müller N, Herold MJ, Van Den Brandt J, Reichardt HM. Glucocorticoids exert opposing effects on macrophage function dependent on their concentration. Immunology (2007) 122:47-53. doi:10.1111/j.1365-2567.2007.02611.x
-
(2007)
Immunology
, vol.122
, pp. 47-53
-
-
Lim, H.-Y.1
Müller, N.2
Herold, M.J.3
Van Den Brandt, J.4
Reichardt, H.M.5
-
75
-
-
84855326534
-
The glucocorticoid dexamethasone programs human dendritic cells for enhanced phagocytosis of apoptotic neutrophils and inflammatory response
-
Hodrea J, Majai G, Doró Z, Zahuczky G, Pap A, Rajnavölgyi É, et al. The glucocorticoid dexamethasone programs human dendritic cells for enhanced phagocytosis of apoptotic neutrophils and inflammatory response. J Leukoc Biol (2012) 91:127-36. doi:10.1189/jlb.0511243
-
(2012)
J Leukoc Biol
, vol.91
, pp. 127-136
-
-
Hodrea, J.1
Majai, G.2
Doró, Z.3
Zahuczky, G.4
Pap, A.5
Rajnavölgyi, É.6
-
76
-
-
84864743193
-
Annexin A1 modulates natural and glucocorticoid-induced resolution of inflammation by enhancing neutrophil apoptosis
-
Vago JP, Nogueira CRC, Tavares LP, Soriani FM, Lopes F, Russo RC, et al. Annexin A1 modulates natural and glucocorticoid-induced resolution of inflammation by enhancing neutrophil apoptosis. J Leukoc Biol (2012) 92:249-58. doi:10.1189/jlb.0112008
-
(2012)
J Leukoc Biol
, vol.92
, pp. 249-258
-
-
Vago, J.P.1
Nogueira, C.R.C.2
Tavares, L.P.3
Soriani, F.M.4
Lopes, F.5
Russo, R.C.6
-
77
-
-
2342533140
-
Mechanisms of glucocorticoid-induced down-regulation of neutrophil L-selectin in cattle: evidence for effects at the gene-expression level and primarily on blood neutrophils
-
Weber PSD. Mechanisms of glucocorticoid-induced down-regulation of neutrophil L-selectin in cattle: evidence for effects at the gene-expression level and primarily on blood neutrophils. J Leukoc Biol (2003) 75:815-27. doi:10.1189/jlb.1003505
-
(2003)
J Leukoc Biol
, vol.75
, pp. 815-827
-
-
Weber, P.S.D.1
-
78
-
-
84959527675
-
Eosinophil resistance to glucocorticoid-induced apoptosis is mediated by the transcription factor NFIL3
-
Pazdrak K, Moon Y, Straub C, Stafford S, Kurosky A. Eosinophil resistance to glucocorticoid-induced apoptosis is mediated by the transcription factor NFIL3. Apoptosis (2016) 21:421-31. doi:10.1007/s10495-016-1226-5
-
(2016)
Apoptosis
, vol.21
, pp. 421-431
-
-
Pazdrak, K.1
Moon, Y.2
Straub, C.3
Stafford, S.4
Kurosky, A.5
-
79
-
-
84956881092
-
Glucocorticoid receptor binds half sites as a monomer and regulates specific target genes
-
Schiller BJ, Chodankar R, Watson LC, Stallcup MR, Yamamoto KR. Glucocorticoid receptor binds half sites as a monomer and regulates specific target genes. Genome Biol (2014) 15:418. doi:10.1186/PREACCEPT-2066059439130185
-
(2014)
Genome Biol
, vol.15
, pp. 418
-
-
Schiller, B.J.1
Chodankar, R.2
Watson, L.C.3
Stallcup, M.R.4
Yamamoto, K.R.5
-
80
-
-
84895814467
-
Dominance of the strongest: inflammatory cytokines versus glucocorticoids
-
Dejager L, Vandevyver S, Petta I, Libert C. Dominance of the strongest: inflammatory cytokines versus glucocorticoids. Cytokine Growth Factor Rev (2014) 25:21-33. doi:10.1016/j.cytogfr.2013.12.006
-
(2014)
Cytokine Growth Factor Rev
, vol.25
, pp. 21-33
-
-
Dejager, L.1
Vandevyver, S.2
Petta, I.3
Libert, C.4
|