A Multi-Lineage Screen Reveals mTORC1 Inhibition Enhances Human Pluripotent Stem Cell Mesendoderm and Blood Progenitor Production

Stem Cell Reports

Volumn 6, Issue 5, 2016, Pages 679-691

  Nazareth, Emanuel Joseph Paul ^a   Rahman, Nafees ^a,b   Yin, Ting ^a   Zandstra, Peter William ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ACTIVIN A; BONE MORPHOGENETIC PROTEIN 4; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; RAPAMYCIN; SMALL INTERFERING RNA; ACTIVIN; BMP4 PROTEIN, HUMAN; BRACHYURY PROTEIN; ENZYME INHIBITOR; FETOPROTEIN; PHOSPHOTRANSFERASE; REGULATORY ASSOCIATED PROTEIN OF MTOR; T BOX TRANSCRIPTION FACTOR;

ARTICLE; CELL DIFFERENTIATION; CELL LINEAGE; COLONY FORMING CELL; CONTROLLED STUDY; DOSE RESPONSE; DRUG POTENTIATION; DRUG SCREENING; EMBRYO; ENDODERM; GENE SILENCING; GERM LAYER; HEMANGIOBLAST; HUMAN; HUMAN CELL; MESENDODERM; MESODERM; NEUROECTODERM; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; ANTAGONISTS AND INHIBITORS; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOLECULAR LIBRARY; PHARMACOLOGY; TUMOR MICROENVIRONMENT;

ACTIVINS; BONE MORPHOGENETIC PROTEIN 4; CELL DIFFERENTIATION; CELL LINEAGE; CELLULAR MICROENVIRONMENT; ENDODERM; ENZYME INHIBITORS; FETAL PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; NEURAL PLATE; PHOSPHOTRANSFERASES; PLURIPOTENT STEM CELLS; REGULATORY-ASSOCIATED PROTEIN OF MTOR; SIROLIMUS; SMALL MOLECULE LIBRARIES; T-BOX DOMAIN PROTEINS;

EID: 84964658609     PISSN: 22136711     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.stemcr.2016.04.003     Document Type: Article

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