FGF signalling inhibits neural induction in human embryonic stem cells

EMBO Journal

Volumn 30, Issue 24, 2011, Pages 4874-4884

  Greber, Boris ^a   Coulon, Philippe ^b,c   Zhang, Miao ^a   Moritz, Sören ^a   Frank, Stefan ^a   Müller Molina, Arnoldo José ^a   Araúzo Bravo, Marcos J ^a   Han, Dong Wook ^a,d   Pape, Hans Christian ^b,c   Schöler, Hans R ^a,b  

^a MAX PLANCK INSTITUTE FOR MOLECULAR BIOMEDICINE   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

^c Institute of Experimental Epilepsy Research   (Germany)

^d Konkuk University School of Medicine   (South Korea)

Author keywords

FGF2; human ES cells; neuroectoderm; PAX6; sensory neurons

Indexed keywords

BONE MORPHOGENETIC PROTEIN; FIBROBLAST GROWTH FACTOR; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE; OCTAMER TRANSCRIPTION FACTOR 4; SMAD1 PROTEIN; SMAD2 PROTEIN; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR OTX2; TRANSCRIPTION FACTOR PAX6; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; CELL DIFFERENTIATION; CELL FATE; CELL LINEAGE; CELL RENEWAL; DOWN REGULATION; EMBRYO; EMBRYONIC STEM CELL; ENZYME INHIBITION; GENE; HAND1 GENE; HUMAN; HUMAN CELL; NANOG GENE; NERVE CELL; NERVE CELL DIFFERENTIATION; NERVE REGENERATION; NEURAL CREST; NEUROECTODERM; OCT4 GENE; PAX6 GENE; PERIPHERAL NERVE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SOX2 GENE; UPREGULATION;

BONE MORPHOGENETIC PROTEINS; CELL LINE; EMBRYONIC STEM CELLS; EYE PROTEINS; FIBROBLAST GROWTH FACTORS; HOMEODOMAIN PROTEINS; HUMANS; MAP KINASE SIGNALING SYSTEM; NEURAL PLATE; OCTAMER TRANSCRIPTION FACTOR-3; OTX TRANSCRIPTION FACTORS; PAIRED BOX TRANSCRIPTION FACTORS; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; SMAD1 PROTEIN; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 83555164640     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2011.407     Document Type: Article

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