Broad impact of deleting endogenous cannabinoid hydrolyzing enzymes and the CB1 cannabinoid receptor on the endogenous cannabinoid-related lipidome in eight regions of the mouse brain

Pharmacological Research

Volumn 110, Issue , 2016, Pages 159-172

  Leishman, Emma ^a   Cornett, Ben ^a   Spork, Karl ^a   Straiker, Alex ^a   MacKie, Ken ^a   Bradshaw, Heather B ^a  

^a INDIANA UNIVERSITY   (United States)

Author keywords

Arachidonic acid; CB1; Endogenous cannabinoid; FAAH; Lipidomics; MAGL

Indexed keywords

2 ARACHIDONOYLGLYCEROL; ACYLGLYCEROL LIPASE; ANANDAMIDE; ARACHIDONIC ACID; CANNABINOID; CANNABINOID 1 RECEPTOR; FATTY ACID AMIDASE; LIPIDOME; METHANOL; PROSTAGLANDIN E2; ACYLGLYCEROL; AMIDASE; ARACHIDONIC ACID DERIVATIVE; CNR1 PROTEIN, MOUSE; ENDOCANNABINOID; FATTY-ACID AMIDE HYDROLASE; GLYCERYL 2-ARACHIDONATE; N-ARACHIDONOYLETHANOLAMINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN REGION; BRAIN STEM; CEREBELLUM; CONTROLLED STUDY; CORPUS STRIATUM; GENE DELETION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIPPOCAMPUS; HYPOTHALAMUS; KNOCKOUT MOUSE; LIPID ANALYSIS; LIPID METABOLISM; LIPIDOMICS; MESENCEPHALON; MOUSE; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SOLID PHASE EXTRACTION; STEADY STATE; TANDEM MASS SPECTROMETRY; THALAMUS; WILD TYPE; ANIMAL; BRAIN; C57BL MOUSE; COMPARATIVE STUDY; DEFICIENCY; ENZYMOLOGY; FEMALE; GENETICS; GENOTYPE; HYDROLYSIS; MALE; METABOLISM; METABOLOMICS; PHENOTYPE; PROCEDURES;

AMIDOHYDROLASES; ANIMALS; ARACHIDONIC ACIDS; BRAIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DINOPROSTONE; ENDOCANNABINOIDS; FEMALE; GENOTYPE; GLYCERIDES; HYDROLYSIS; MALE; METABOLOMICS; MICE, INBRED C57BL; MICE, KNOCKOUT; MONOACYLGLYCEROL LIPASES; PHENOTYPE; RECEPTOR, CANNABINOID, CB1; TANDEM MASS SPECTROMETRY;

EID: 84964620252     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2016.04.020     Document Type: Article

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