메뉴 건너뛰기




Volumn 84, Issue 4, 2003, Pages 698-704

Cannabinoid CB1 receptor knockout mice exhibit markedly reduced voluntary alcohol consumption and lack alcohol-induced dopamine release in the nucleus accumbens

Author keywords

Alcohol; CB1 receptors; Dopamine; Knockout mice; Nucleus accumbens

Indexed keywords

CANNABINOID 1 RECEPTOR; DOPAMINE;

EID: 0037317155     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2003.01576.x     Document Type: Article
Times cited : (298)

References (49)
  • 1
    • 0032526262 scopus 로고    scopus 로고
    • Gender differences in ethanol preference and ingestion in rats. The role of the gonadal steroid environment
    • Almeida O. F., Shoaib M., Deicke J., Fischer D., Darwish M. H. and Patchev V. K. (1998) Gender differences in ethanol preference and ingestion in rats. The role of the gonadal steroid environment. J. Clin. Invest. 101, 2677-2685.
    • (1998) J. Clin. Invest. , vol.101 , pp. 2677-2685
    • Almeida, O.F.1    Shoaib, M.2    Deicke, J.3    Fischer, D.4    Darwish, M.H.5    Patchev, V.K.6
  • 2
    • 0030738512 scopus 로고    scopus 로고
    • Selective inhibition of sucrose and ethanol intake by SR 141716, an antagonist of central cannabinoid (CB1) receptors
    • Amone M., Maruani J., Chaperon F., Thiebot M., Poncelet M., Soubrie P. and Le Fur G. (1997) Selective inhibition of sucrose and ethanol intake by SR 141716, an antagonist of central cannabinoid (CB1) receptors. Psychopharmacology 132, 104-106.
    • (1997) Psychopharmacology , vol.132 , pp. 104-106
    • Amone, M.1    Maruani, J.2    Chaperon, F.3    Thiebot, M.4    Poncelet, M.5    Soubrie, P.6    Le Fur, G.7
  • 3
    • 0033513993 scopus 로고    scopus 로고
    • 35S] GTPγS binding in synaptic plasma membrane from chronic ethanol exposed mouse
    • 35S] GTPγS binding in synaptic plasma membrane from chronic ethanol exposed mouse. Brain Res. 815, 89-97.
    • (1999) Brain Res. , vol.815 , pp. 89-97
    • Basavarajappa, B.S.1    Hungund, B.L.2
  • 4
    • 0032958688 scopus 로고    scopus 로고
    • Chronic ethanol increases the cannabinoid receptor agonist, anandamide and its precursor N-arachidonyl phosphatidyl ethanolamine in SK-N-SH cells
    • Basavarajappa B. S. and Hungund B. L. (1999b) Chronic ethanol increases the cannabinoid receptor agonist, anandamide and its precursor N-arachidonyl phosphatidyl ethanolamine in SK-N-SH cells. J. Neurochem. 72, 522-528.
    • (1999) J. Neurochem. , vol.72 , pp. 522-528
    • Basavarajappa, B.S.1    Hungund, B.L.2
  • 5
    • 0035872295 scopus 로고    scopus 로고
    • 35S]Guanosine TriphosphateγS binding in the brain of C57BL/6 and DBA/2 mice
    • 35S]Guanosine TriphosphateγS binding in the brain of C57BL/6 and DBA/2 mice. J. Neurosci. Res. 64, 429-436.
    • (2001) J. Neurosci. Res. , vol.64 , pp. 429-436
    • Basavarajappa, B.S.1    Hungund, B.L.2
  • 6
    • 0036019414 scopus 로고    scopus 로고
    • Neuromodulatory role of the endocannabinoid signaling system in alcoholism: An overview
    • Basavarajappa B. S. and Hungund B. L. (2002) Neuromodulatory role of the endocannabinoid signaling system in alcoholism: an overview. Prostaglandins Leukot. Essent. Fatty Acids 66, 287-299.
    • (2002) Prostaglandins Leukot. Essent. Fatty Acids , vol.66 , pp. 287-299
    • Basavarajappa, B.S.1    Hungund, B.L.2
  • 9
    • 0032543201 scopus 로고    scopus 로고
    • Chronic ethanol administration down-regulates cannabinoid receptors in mouse brain synaptic plasma membrane
    • Basavarajappa B. S., Cooper T. B. and Hungund B. L. (1998b) Chronic ethanol administration down-regulates cannabinoid receptors in mouse brain synaptic plasma membrane. Brain Res. 793, 212-218.
    • (1998) Brain Res. , vol.793 , pp. 212-218
    • Basavarajappa, B.S.1    Cooper, T.B.2    Hungund, B.L.3
  • 10
    • 0034672570 scopus 로고    scopus 로고
    • Stimulation of cannabinoid receptor agonist 2-arachidonylglycerol by chronic ethanol and its modulation by specific neuromodulators in cerebellar granule neurons
    • Basavarajappa B. S., Saito M., Cooper T. B. and Hungund B. L. (2000) Stimulation of cannabinoid receptor agonist 2-arachidonylglycerol by chronic ethanol and its modulation by specific neuromodulators in cerebellar granule neurons. Biochim. Biophys. Acta 1535, 78-86.
    • (2000) Biochim. Biophys. Acta , vol.1535 , pp. 78-86
    • Basavarajappa, B.S.1    Saito, M.2    Cooper, T.B.3    Hungund, B.L.4
  • 11
    • 0036748948 scopus 로고    scopus 로고
    • SR141716, a central cannabinoid (CB1) receptor antagonist, blocks the motivational and dopamine-releasing effects of nicotine in rats
    • Cohen C., Perrault G., Voltz C., Steinberg R. and Soubrie P. (2002) SR141716, a central cannabinoid (CB1) receptor antagonist, blocks the motivational and dopamine-releasing effects of nicotine in rats. Behav. Pharmacol. 13, 451-463.
    • (2002) Behav. Pharmacol. , vol.13 , pp. 451-463
    • Cohen, C.1    Perrault, G.2    Voltz, C.3    Steinberg, R.4    Soubrie, P.5
  • 12
    • 0031926412 scopus 로고    scopus 로고
    • Reduction of voluntary ethanol intake in ethanol-preferring sP rats by the cannabinoid antagonist SR-141716
    • Colombo G., Agabio R., Fa M., Guano L., Lobina C., Loche A., Reali R. and Gessa G. (1998) Reduction of voluntary ethanol intake in ethanol-preferring sP rats by the cannabinoid antagonist SR-141716. Alcohol Alcohol. 33, 126-130.
    • (1998) Alcohol Alcohol , vol.33 , pp. 126-130
    • Colombo, G.1    Agabio, R.2    Fa, M.3    Guano, L.4    Lobina, C.5    Loche, A.6    Reali, R.7    Gessa, G.8
  • 15
    • 0343933624 scopus 로고
    • Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats
    • Di Chiara G. and Imperato A. (1988) Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proc. Natl Acad. Sci. USA 85, 5274-5278.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 5274-5278
    • Di Chiara, G.1    Imperato, A.2
  • 16
    • 0032401036 scopus 로고    scopus 로고
    • Endocannabinoids: Endogenous cannabinoid receptor ligands with neuromodulatory action
    • Di Marzo V., Melck D., Bisogno T. and De Petrocellis L. (1998) Endocannabinoids: endogenous cannabinoid receptor ligands with neuromodulatory action. Trends Neurosci. 21, 521-528.
    • (1998) Trends Neurosci. , vol.21 , pp. 521-528
    • Di Marzo, V.1    Melck, D.2    Bisogno, T.3    De Petrocellis, L.4
  • 19
    • 0032901227 scopus 로고    scopus 로고
    • The motivation for beer in rats: Effects of ritanserin, naloxone and SR 141716
    • Gallate J. E. and McGregor I. S. (1999) The motivation for beer in rats: effects of ritanserin, naloxone and SR 141716. Psychopharmacology 142, 302-308.
    • (1999) Psychopharmacology , vol.142 , pp. 302-308
    • Gallate, J.E.1    McGregor, I.S.2
  • 20
    • 0032952420 scopus 로고    scopus 로고
    • Increased motivation for beer in rats following administration of a cannabinoid CB1 receptor agonist
    • Gallate J. E., Saharov T., Mallet P. E. and McGregor I. S. (1999) Increased motivation for beer in rats following administration of a cannabinoid CB1 receptor agonist. Eur. J. Pharmacol. 370, 233-240.
    • (1999) Eur. J. Pharmacol. , vol.370 , pp. 233-240
    • Gallate, J.E.1    Saharov, T.2    Mallet, P.E.3    McGregor, I.S.4
  • 21
    • 0032472382 scopus 로고    scopus 로고
    • Cannabinoids activate mesolimbic dopamine neurons by an action on cannabinoid CB1 receptors
    • Gessa G. L., Melis M., Muntoni A. L. and Diana M. (1998) Cannabinoids activate mesolimbic dopamine neurons by an action on cannabinoid CB1 receptors. Eur. J. Pharmacol. 341, 39-44.
    • (1998) Eur. J. Pharmacol. , vol.341 , pp. 39-44
    • Gessa, G.L.1    Melis, M.2    Muntoni, A.L.3    Diana, M.4
  • 22
    • 0033667111 scopus 로고    scopus 로고
    • The endocannabinoid system: A physiological perspective on its role in psychomotor control
    • Giuffrida A. and Piomelli D. (2000) The endocannabinoid system: a physiological perspective on its role in psychomotor control. Chem. Phys. Lipids 108, 151-158.
    • (2000) Chem. Phys. Lipids , vol.108 , pp. 151-158
    • Giuffrida, A.1    Piomelli, D.2
  • 24
    • 0000815267 scopus 로고
    • Characterization and localization of cannabinoid receptors in rat brain: A quantitative in vitro autoradiographic study
    • Herkenham M., Lynn A. B., Johnson M. R., Melvin L. S., de Cost B. R. and Rice K. C. (1991) Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic study. J. Neurosci. 16, 8057-8066.
    • (1991) J. Neurosci. , vol.16 , pp. 8057-8066
    • Herkenham, M.1    Lynn, A.B.2    Johnson, M.R.3    Melvin, L.S.4    De Cost, B.R.5    Rice, K.C.6
  • 25
    • 0034018628 scopus 로고    scopus 로고
    • Are anandamide and cannabinoid receptors involved in ethanol tolerance? A review of the evidence
    • Hungund B. L. and Basavarajappa B. S. (2000a) Are anandamide and cannabinoid receptors involved in ethanol tolerance? A review of the evidence. Alcohol Alcohol. 35, 126-133.
    • (2000) Alcohol Alcohol , vol.35 , pp. 126-133
    • Hungund, B.L.1    Basavarajappa, B.S.2
  • 26
    • 0002320994 scopus 로고    scopus 로고
    • Role of brain's own marijuana, anandamide and its cannabinoid receptors (CB1) in alcoholism
    • Pandalai R. S., ed., Trivandrum, India
    • Hungund B. L. and Basavarajappa B. S. (2000b) Role of brain's own marijuana, anandamide and its cannabinoid receptors (CB1) in alcoholism, in Recent Research Development in Neurochemistry, Vol. 3 (Pandalai R. S., ed.), pp. 9-26. Trivandrum, India.
    • (2000) Recent Research Development in Neurochemistry , vol.3 , pp. 9-26
    • Hungund, B.L.1    Basavarajappa, B.S.2
  • 27
    • 0034067080 scopus 로고    scopus 로고
    • Distinct differences in the cannabinoid receptor binding in the brain of C57BL/6 and DBA/2 mice, selected for their differences in voluntary ethanol consumption
    • Hungund B. L. and Basavarajappa B. S. (2000c) Distinct differences in the cannabinoid receptor binding in the brain of C57BL/6 and DBA/2 mice, selected for their differences in voluntary ethanol consumption. J. Neurosci. Res. 60, 122-128.
    • (2000) J. Neurosci. Res. , vol.60 , pp. 122-128
    • Hungund, B.L.1    Basavarajappa, B.S.2
  • 29
    • 0035199891 scopus 로고    scopus 로고
    • Drug addiction, dysregulation of reward, and allostasis
    • Koob G. F. and Le Moal M. (2001) Drug addiction, dysregulation of reward, and allostasis. Neuropsychopharmacology 24, 97-129.
    • (2001) Neuropsychopharmacology , vol.24 , pp. 97-129
    • Koob, G.F.1    Le Moal, M.2
  • 30
    • 0032938057 scopus 로고    scopus 로고
    • Brain reward circuits in alcoholism
    • Koob G. F. and Roberts A. J. (1999) Brain reward circuits in alcoholism. CNS Spectrums 4, 23-37.
    • (1999) CNS Spectrums , vol.4 , pp. 23-37
    • Koob, G.F.1    Roberts, A.J.2
  • 31
    • 0027482872 scopus 로고
    • Dopaminergic regulation of cannabinoid receptor mRNA levels in the rat caudate-putamen: An in situ hybridization study
    • Mailleux P. and Vanderhaeghen J. J. (1993) Dopaminergic regulation of cannabinoid receptor mRNA levels in the rat caudate-putamen: an in situ hybridization study. J. Neurochem. 61, 1705-1712.
    • (1993) J. Neurochem. , vol.61 , pp. 1705-1712
    • Mailleux, P.1    Vanderhaeghen, J.J.2
  • 33
    • 0025325535 scopus 로고
    • Structure of a cannabinoid receptor and functional expression of the cloned cDNA
    • Matsuda L. A., Lolait S. J., Brownstein M. J., Young A. C. and Bonner T. I. (1990) Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature 346, 561-564.
    • (1990) Nature , vol.346 , pp. 561-564
    • Matsuda, L.A.1    Lolait, S.J.2    Brownstein, M.J.3    Young, A.C.4    Bonner, T.I.5
  • 34
    • 0032466081 scopus 로고    scopus 로고
    • Animal models of alcoholism: Neurobiology of high alcohol-drinking behavior in rodents
    • McBride W. J. and Li T. K. (1998) Animal models of alcoholism: neurobiology of high alcohol-drinking behavior in rodents. Crit. Rev. Neurobiol. 12, 339-369.
    • (1998) Crit. Rev. Neurobiol. , vol.12 , pp. 339-369
    • McBride, W.J.1    Li, T.K.2
  • 36
    • 0030043694 scopus 로고    scopus 로고
    • Identification of sex-specific quantitative trait loci controlling alcohol preference in C57BL/6 mice
    • Melo J. A., Shendure J., Pociask K. and Silver L. M. (1996) Identification of sex-specific quantitative trait loci controlling alcohol preference in C57BL/6 mice [see comments]. Nat. Genet. 13, 147-153.
    • (1996) Nat. Genet. , vol.13 , pp. 147-153
    • Melo, J.A.1    Shendure, J.2    Pociask, K.3    Silver, L.M.4
  • 37
  • 38
    • 0034054167 scopus 로고    scopus 로고
    • Microdialysis in the mouse nucleus accumbens: A method for detection of monoamine and amino acid neurotransmitters with simultaneous assessment of locomotor activity
    • Olive M. F., Mehmert K. K. and Hodge C. W. (2000) Microdialysis in the mouse nucleus accumbens: a method for detection of monoamine and amino acid neurotransmitters with simultaneous assessment of locomotor activity. Brain Res. Brain Res. Protoc. 5, 16-24.
    • (2000) Brain Res. Brain Res. Protoc. , vol.5 , pp. 16-24
    • Olive, M.F.1    Mehmert, K.K.2    Hodge, C.W.3
  • 41
    • 0032794966 scopus 로고    scopus 로고
    • Cannabinoid receptor antagonist SR141716A decreases operant ethanol self administration in rats exposed to ethanol-vapor chambers
    • Rodriguez de Fonseca F., Roberts A. J., Bilbao A. and Koob G. F. (1999) Cannabinoid receptor antagonist SR141716A decreases operant ethanol self administration in rats exposed to ethanol-vapor chambers. Zhongguo Yao Li Xue Bao 20, 1109-1114.
    • (1999) Zhongguo Yao Li Xue Bao , vol.20 , pp. 1109-1114
    • Rodriguez de Fonseca, F.1    Roberts, A.J.2    Bilbao, A.3    Koob, G.F.4
  • 43
    • 13044311373 scopus 로고    scopus 로고
    • Altered gene expression in striatal projection neurons in CB1 cannabinoid receptor knockout mice
    • Steiner H., Bonner T. I., Zimmer A. M., Kitai S. T. and Zimmer A. (1999) Altered gene expression in striatal projection neurons in CB1 cannabinoid receptor knockout mice. Proc. Natl Acad. Sci. USA 96, 5786-5790.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 5786-5790
    • Steiner, H.1    Bonner, T.I.2    Zimmer, A.M.3    Kitai, S.T.4    Zimmer, A.5
  • 45
    • 0344199383 scopus 로고    scopus 로고
    • Effects of cannabinoids on dopamine release in the corpus striatum and the nucleus accumbens in vitro
    • Szabo B., Muller T. and Koch H. (1999) Effects of cannabinoids on dopamine release in the corpus striatum and the nucleus accumbens in vitro. J. Neurochem. 73, 1084-1089.
    • (1999) J. Neurochem. , vol.73 , pp. 1084-1089
    • Szabo, B.1    Muller, T.2    Koch, H.3
  • 46
    • 0030761521 scopus 로고    scopus 로고
    • Cannabinoid and heroin activation of mesolimbic dopamine transmission by a common mu1 opioid receptor mechanism
    • Tanda G., Pontieri F. E. and Di Chiara G. (1997) Cannabinoid and heroin activation of mesolimbic dopamine transmission by a common mu1 opioid receptor mechanism. Science 276, 2048-2050.
    • (1997) Science , vol.276 , pp. 2048-2050
    • Tanda, G.1    Pontieri, F.E.2    Di Chiara, G.3
  • 48
    • 0042987703 scopus 로고    scopus 로고
    • Comparison of local and systemic ethanol effects on extracellular dopamine concentration in rat nucleus accumbens by microdialysis
    • Yim H. J., Schallert T., Randall P. K. and Gonzales R. A. (1998) Comparison of local and systemic ethanol effects on extracellular dopamine concentration in rat nucleus accumbens by microdialysis. Alcohol. Clin. Exp. Res. 22, 367-374.
    • (1998) Alcohol. Clin. Exp. Res. , vol.22 , pp. 367-374
    • Yim, H.J.1    Schallert, T.2    Randall, P.K.3    Gonzales, R.A.4
  • 49
    • 0033545866 scopus 로고    scopus 로고
    • Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice
    • Zimmer A., Zimmer A. M., Hohmann A. G., Herkenham M. and Bonner T. I. (1999) Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice. Proc. Natl Acad. Sci. USA 96, 5780-5785.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 5780-5785
    • Zimmer, A.1    Zimmer, A.M.2    Hohmann, A.G.3    Herkenham, M.4    Bonner, T.I.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.