Identification of a New Class of Molecules, the Arachidonyl Amino Acids, and Characterization of One Member That Inhibits Pain

Journal of Biological Chemistry

Volumn 276, Issue 46, 2001, Pages 42639-42644

  Huang, Susan M ^a   Bisogno, Tiziana ^b   Petros, Timothy J ^a   Chang, Sai Y ^d   Zavitsanos, Paul A ^e   Zipkin, Robert E ^f   Sivakumar, Ramachandran ^f   Coop, Andrew ^g   Maeda, Dean Y ^g   De Petrocellis, Luciano ^c   Burstein, Sumner ^h   Di Marzo, Vincenzo ^b   Walker, J Michael ^a  

^a BROWN UNIVERSITY   (United States)

^b Istituto per la Chimica di Molecole di Interesse Biologico   (Italy)

^c CNR   (Italy)

^d Applied Biosystems Framingham   (United States)

^e AGILENT TECHNOLOGIES   (United States)

^f BIOMOL Research Laboratories Inc   (United States)

^g UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

^h UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOSYNTHESIS; ENZYMES; FATTY ACIDS; LIPIDS; TISSUE;

SIGNALING MOLECULES;

MOLECULAR BIOLOGY;

AMINO ACID DERIVATIVE; GLYCINE; LIPID; N ARACHIDONYL GAMMA AMINOBUTYRIC ACID; N ARACHIDONYLALANINE; UNCLASSIFIED DRUG; 4 AMINOBUTYRIC ACID; ALANINE; AMIDASE; AMIDE; AMINO ACID; ANANDAMIDE; ARACHIDONIC ACID; ARACHIDONIC ACID DERIVATIVE; CALCIUM; FATTY ACID AMIDASE; FATTY-ACID AMIDE HYDROLASE; FORMALDEHYDE;

ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; CATTLE; CONJUGATE; DEGRADATION; MAMMAL; NONHUMAN; PAIN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; ANIMAL; BRAIN; CHEMICAL MODEL; CHEMISTRY; CLASSIFICATION; DOSE RESPONSE; KINETICS; MASS FRAGMENTOGRAPHY; METABOLISM; PROTEIN BINDING; TIME; TISSUE DISTRIBUTION;

ANIMALIA; BOS TAURUS; BOVINAE; MAMMALIA;

ALANINE; AMIDOHYDROLASES; AMINO ACIDS; ANIMALS; ARACHIDONIC ACID; ARACHIDONIC ACIDS; BRAIN; CALCIUM; CATTLE; DOSE-RESPONSE RELATIONSHIP, DRUG; FORMALDEHYDE; GAMMA-AMINOBUTYRIC ACID; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GLYCINE; KINETICS; MODELS, CHEMICAL; PAIN; POLYUNSATURATED ALKAMIDES; PROTEIN BINDING; RATS; SIGNAL TRANSDUCTION; TIME FACTORS; TISSUE DISTRIBUTION;

EID: 0035900694     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M107351200     Document Type: Article

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