Negative regulation of leptin-induced reactive oxygen species (ROS) formation by cannabinoid CB1 receptor activation in hypothalamic neurons

Journal of Biological Chemistry

Volumn 290, Issue 22, 2015, Pages 13669-13677

  Palomba, Letizia ^a,b   Silvestri, Cristoforo ^b,c   Imperatore, Roberta ^b   Morello, Giovanna ^b   Piscitelli, Fabiana ^b   Martella, Andrea ^b   Cristino, Luigia ^b   Di Marzo, Vincenzo ^b  

^a UNIVERSITY OF URBINO   (Italy)

^b CNR   (Italy)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CHEMICAL ACTIVATION; MAMMALS; MOLECULAR BIOLOGY; NEURONS; OXYGEN;

CATALASE ACTIVITY; GENETIC INHIBITION; HYPOTHALAMIC NEURON; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; REACTIVE OXYGEN SPECIES; RECEPTOR ACTIVATION; RECEPTOR ACTIVITY; REGULATORY EFFECTS;

HORMONES;

2 CHLORO 5 NITRO N (4 PYRIDYL)BENZAMIDE; AMIDE; ARACHIDONYL 2' CHLOROETHYLAMIDE; CANNABINOID 1 RECEPTOR; CATALASE; LEPTIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; REACTIVE OXYGEN METABOLITE; TROGLITAZONE; UNCLASSIFIED DRUG; 2,4 THIAZOLIDINEDIONE DERIVATIVE; ARACHIDONIC ACID DERIVATIVE; ARACHIDONYL-2-CHLOROETHYLAMIDE; BENZAMIDE DERIVATIVE; CANNABINOID; CHROMAN DERIVATIVE; ENDOCANNABINOID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PYRIDINE DERIVATIVE; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; BIOACCUMULATION; CONTROLLED STUDY; DEGRADATION KINETICS; ENZYME ACTIVITY; ENZYME INHIBITION; HYPOTHALAMUS; MOUSE; NEGATIVE REGULATION; NERVE CELL CULTURE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; ADIPOCYTE; ANIMAL; BODY WEIGHT; C57BL MOUSE; CELL CULTURE; CHEMISTRY; CYTOLOGY; GENE EXPRESSION REGULATION; GENE SILENCING; HYDROLYSIS; METABOLISM; NERVE CELL; NEWBORN;

MUS;

ADIPOCYTES; ANIMALS; ANIMALS, NEWBORN; ARACHIDONIC ACIDS; BENZAMIDES; BODY WEIGHT; CANNABINOIDS; CATALASE; CELLS, CULTURED; CHROMANS; ENDOCANNABINOIDS; GENE EXPRESSION REGULATION; GENE SILENCING; HYDROLYSIS; HYPOTHALAMUS; LEPTIN; MICE; MICE, INBRED C57BL; NEURONS; PPAR ALPHA; PPAR GAMMA; PYRIDINES; REACTIVE OXYGEN SPECIES; RECEPTOR, CANNABINOID, CB1; RNA, SMALL INTERFERING; THIAZOLIDINEDIONES;

EID: 84930216540     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.646885     Document Type: Article

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