Genetic deletion of monoacylglycerol lipase leads to impaired cannabinoid receptor CB1R signaling and anxiety-like behavior

Journal of Neurochemistry

Volumn 135, Issue 4, 2015, Pages 799-813

  Imperatore, Roberta ^a   Morello, Giovanna ^a,b   Luongo, Livio ^c   Taschler, Ulrike ^d   Romano, Rosaria ^c   De Gregorio, Danilo ^c   Belardo, Carmela ^c   Maione, Sabatino ^c   Di Marzo, Vincenzo ^a   Cristino, Luigia ^a  

^a CNR   (Italy)

^b UNIVERSITY OF VERONA   (Italy)

^c SECOND UNIVERSITY OF NAPLES   (Italy)

^d UNIVERSITY OF GRAZ   (Austria)

Author keywords

2 arachidonoylglycerol (2 AG); anxiety like behavior; CB1R; endocannabinoids; MAGL KO mice; synaptic plasticity

Indexed keywords

2 ARACHIDONOYLGLYCEROL; ACYLGLYCEROL LIPASE; BETA ARRESTIN 2; CANNABINOID 1 RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; VESICULAR GLUTAMATE TRANSPORTER 1; 2-ARACHIDONYLGLYCEROL; ACYLGLYCEROL; ARACHIDONIC ACID DERIVATIVE; BETA ARRESTIN; ENDOCANNABINOID; GLUTAMIC ACID; RETINA S ANTIGEN;

AMINO ACID TRANSPORT; AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY LIKE BEHAVIOR; ARTICLE; BASOLATERAL AMYGDALA; BEHAVIOR; CEREBELLUM CORTEX; CONTROLLED STUDY; DEPRESSION; DESENSITIZATION; EMOTIONALITY; EXCITATORY TRANSMISSION; GENE DELETION; GENETIC MODEL; GLUTAMATE RELEASE; HIPPOCAMPUS; IMMUNOREACTIVITY; INHIBITORY TRANSMISSION; KNOCKOUT MOUSE; MAGL GENE; MEDIAL PREFRONTAL CORTEX; MOLECULAR DYNAMICS; MORPHOLOGY; MOUSE; NEUROTRANSMISSION; NONHUMAN; OBSESSIVE COMPULSIVE DISORDER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; ACTION POTENTIAL; ANIMAL; ANXIETY; BRAIN; C57BL MOUSE; DEFICIENCY; DISEASE MODEL; EXPLORATORY BEHAVIOR; GENE EXPRESSION REGULATION; GENETICS; IMMOBILIZATION; IMMUNOPRECIPITATION; LIPID METABOLISM; METABOLISM; MICRODIALYSIS; PHYSIOLOGY; TRANSGENIC MOUSE;

ACTION POTENTIALS; ANIMALS; ANXIETY; ARACHIDONIC ACIDS; ARRESTINS; BRAIN; DISEASE MODELS, ANIMAL; ENDOCANNABINOIDS; EXPLORATORY BEHAVIOR; GENE EXPRESSION REGULATION; GLUTAMIC ACID; GLYCERIDES; HINDLIMB SUSPENSION; IMMUNOPRECIPITATION; LIPID METABOLISM; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICRODIALYSIS; MONOACYLGLYCEROL LIPASES; RECEPTOR, CANNABINOID, CB1; VESICULAR GLUTAMATE TRANSPORT PROTEIN 1;

EID: 84946493468     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.13267     Document Type: Article

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