Liquiritigenin reverses depression-like behavior in unpredictable chronic mild stress-induced mice by regulating PI3K/Akt/mTOR mediated BDNF/TrkB pathway

Behavioural Brain Research

Volumn 308, Issue , 2016, Pages 177-186

  Tao, Weiwei ^a   Dong, Yu ^a   Su, Qiang ^a   Wang, Hanqing ^b   Chen, Yanyan ^a   Xue, Wenda ^a   Chen, Chang ^a   Xia, Baomei ^a   Duan, Jinao ^a   Chen, Gang ^a  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b NINGXIA MEDICAL UNIVERSITY   (China)

Author keywords

BDNF TrkB; Depression; Liquiritigenin; PI3 K Akt mTOR

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; CATALASE; FLUOXETINE; GLUCOCORTICOID; GLUTATHIONE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIQUIRITIGENIN; MALONALDEHYDE; MAMMALIAN TARGET OF RAPAMYCIN; NORADRENALIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SEROTONIN; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA; ANTIDEPRESSANT AGENT; CYTOKINE; FLAVANONE DERIVATIVE; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDEPRESSANT ACTIVITY; ARTICLE; CHRONIC STRESS; CONTROLLED STUDY; DEPRESSION; DRUG STRUCTURE; FORCED SWIM TEST; HIPPOCAMPUS; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; MALE; MOUSE; NONHUMAN; OPEN FIELD TEST; PRIORITY JOURNAL; PROTEIN EXPRESSION; SERUM; SIGNAL TRANSDUCTION; SUCROSE PREFERENCE TEST; TAIL SUSPENSION TEST; UNPREDICTABLE CHRONIC MILD STRESS; UPREGULATION; ANIMAL; CHEMISTRY; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; EXPLORATORY BEHAVIOR; FOOD DEPRIVATION; FOOD PREFERENCE; INSTITUTE FOR CANCER RESEARCH MOUSE; MENTAL STRESS; METABOLISM; WATER DEPRIVATION;

ANIMALS; ANTIDEPRESSIVE AGENTS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CYTOKINES; DEPRESSION; DISEASE MODELS, ANIMAL; EXPLORATORY BEHAVIOR; FLAVANONES; FOOD DEPRIVATION; FOOD PREFERENCES; MALE; MICE; MICE, INBRED ICR; NOREPINEPHRINE; PHOSPHATIDYLINOSITOL 3-KINASES; REACTIVE OXYGEN SPECIES; SEROTONIN; SIGNAL TRANSDUCTION; STRESS, PSYCHOLOGICAL; WATER DEPRIVATION;

EID: 84964440223     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2016.04.039     Document Type: Article

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