Neuroprotective effects of DAHP and Triptolide in focal cerebral ischemia via apoptosis inhibition and PI3K/Akt/mTOR pathway activation

Frontiers in Neuroanatomy

Volumn 9, Issue APR, 2015, Pages

  Li, Weiyun ^a   Yang, Yang ^a   Hu, Zhiying ^b   Ling, Shucai ^a   Fang, Marong ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b Hangzhou Red Cross Hospital   (China)

Author keywords

Anti apoptosis; Cerebral ischemia; DAHP; Neuroprotection; PI3K Akt mTOR; Triptolide

Indexed keywords

2,4 DIAMINO 6 HYDROXYPYRIMIDINE; CASPASE 3; INDUCIBLE NITRIC OXIDE SYNTHASE; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; PROTEIN SERINE THREONINE KINASE; PYRIMIDINE DERIVATIVE; TRIPTOLIDE; UNCLASSIFIED DRUG;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN EDEMA; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENZYME ACTIVATION; IMMUNOFLUORESCENCE MICROSCOPY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING;

EID: 84930506032     PISSN: 16625129     EISSN: 16625129     Source Type: Journal    
DOI: 10.3389/fnana.2015.00048     Document Type: Article

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