P2X7 as a new target for chrysophanol to treat lipopolysaccharide-induced depression in mice

Neuroscience Letters

Volumn 613, Issue , 2016, Pages 60-65

  Zhang, Kai ^a   Liu, Jingyan ^a   You, Xintong ^b   Kong, Ping ^c   Song, Yichen ^a   Cao, Lu ^a   Yang, Song ^d   Wang, Wenbing ^a   Fu, Qiang ^a   Ma, Zhangqiang ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b NANJING FORESTRY UNIVERSITY   (China)

^c Nanjing Hongshi Pharmaceutical Management Services Co   (China)

^d Nanjing Shunan Medical Apparatus Company   (China)

Author keywords

Chrysophanol; Depression; Inflammation; P2X7

Indexed keywords

ANTIDEPRESSANT AGENT; CHRYSOPHANIC ACID; FLUOXETINE; I KAPPA B ALPHA; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; PURINERGIC P2X7 RECEPTOR; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; ANTHRAQUINONE DERIVATIVE; ANTIINFLAMMATORY AGENT; CYTOKINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDEPRESSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEPRESSION; DOWN REGULATION; DRUG EFFECT; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FORCED SWIM TEST; GROOMING; HIPPOCAMPUS; IMMOBILITY; INFLAMMATION; LOCOMOTION; MALE; MOUSE; NONHUMAN; OPEN FIELD TEST; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REARING; SIGNAL TRANSDUCTION; SUCROSE PREFERENCE TEST; TAIL SUSPENSION TEST; TREATMENT DURATION; UPREGULATION; ANIMAL; ANIMAL BEHAVIOR; BIOSYNTHESIS; BLOOD; DRUG EFFECTS; FOOD PREFERENCE; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; MOTIVATION; MOTOR ACTIVITY; PSYCHOLOGY;

ANIMALS; ANTHRAQUINONES; ANTI-INFLAMMATORY AGENTS; ANTIDEPRESSIVE AGENTS; BEHAVIOR, ANIMAL; CYTOKINES; DEPRESSION; FOOD PREFERENCES; HIPPOCAMPUS; LIPOPOLYSACCHARIDES; MALE; MICE, INBRED ICR; MOTIVATION; MOTOR ACTIVITY; NF-KAPPA B; RECEPTORS, PURINERGIC P2X7; SIGNAL TRANSDUCTION;

EID: 84953249987     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2015.12.043     Document Type: Article

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