Bio-inspired pulmonary surfactant-modified nanogels: A promising siRNA delivery system

Journal of Controlled Release

Volumn 206, Issue , 2015, Pages 177-186

  De Backer, Lynn ^a   Braeckmans, Kevin ^a   Stuart, Marc C A ^b   Demeester, Jo ^a   De Smedt, Stefaan C ^a   Raemdonck, Koen ^a  

^a GHENT UNIVERSITY   (Belgium)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

Dextran nanogels Hybrid nanoparticles Lung siRNA delivery Pulmonary surfactant Targeted delivery

Indexed keywords

BIOLOGICAL ORGANS; DEXTRAN; GENE THERAPY; GENES; GENETIC ENGINEERING; MOBILE SECURITY; MOLECULAR BIOLOGY; NANOPARTICLES; NANOSTRUCTURED MATERIALS; PHOSPHOLIPIDS; RESPIRATORY THERAPY; RNA; SHELLS (STRUCTURES);

CLINICAL TRANSLATION; COLLOIDAL STABILITY; HYBRID NANOPARTICLE; INHALATION THERAPY; NANOGELS; PULMONARY SURFACTANTS; RECEPTOR-MEDIATED ENDOCYTOSIS; SMALL INTERFERING RNA (SIRNA);

SURFACE ACTIVE AGENTS;

DEXTRAN; DRUG ADMINISTRATION; DRUG CARRIER; GEL; LUNG SURFACTANT; NANOPARTICLE; SIRNA LOADED DEXTRAN NANOGEL; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CELL FATE; CELL LINE; CHEMISTRY; CONTROLLED STUDY; CYTOLOGY; DRUG DELIVERY SYSTEM; FLUORESCENCE; GEL; GENE DELIVERY SYSTEM; GENE SILENCING; GENETICS; HUMAN; HUMAN CELL; INTERNALIZATION; LUNG; LUNG ALVEOLUS EPITHELIUM CELL; METABOLISM; PRIORITY JOURNAL; RNA INTERFERENCE; TRANSMISSION ELECTRON MICROSCOPY; TUMOR CELL LINE;

ADMINISTRATION AND DOSAGE; CELL LINE; CELL LINE, TUMOR; CHEMISTRY; CYTOLOGY; DEXTRANS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; GELS; GENETICS; HUMANS; LUNG; METABOLISM; PULMONARY SURFACTANTS; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84964311557     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.03.015     Document Type: Article

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