Delivery of small interfering RNA by peptide-targeted mesoporous silica nanoparticle-supported lipid bilayers

ACS Nano

Volumn 6, Issue 3, 2012, Pages 2174-2188

  Ashley, Carlee E ^a,d   Carnes, Eric C ^b,c,d   Epler, Katharine E ^c   Padilla, David P ^c   Phillips, Genevieve K ^d   Castillo, Robert E ^c   Wilkinson, Dan C ^c   Wilkinson, Brian S ^c   Burgard, Cameron A ^c   Kalinich, Robin M ^e   Townson, Jason L ^c   Chackerian, Bryce ^d,f   Willman, Cheryl L ^d,f   Peabody, David S ^d,f   Wharton, Walker ^d,f   Brinker, C Jeffrey ^b,c,d,e,f  

^a SANDIA NATIONAL LABORATORIES   (United States)

^b University of New Mexico   (United States)

^c UNIVERSITY OF NEW MEXICO   (United States)

^d UNIVERSITY OF NEW MEXICO   (United States)

^e SANDIA NATIONAL LABORATORIES   (United States)

^f UNIVERSITY OF NEW MEXICO HEALTH SCIENCES CENTER   (United States)

Author keywords

cancer; lipid nanoparticle; mesoporous silica nanoparticle; peptide ligand; small interfering RNA; supported lipid bilayer; targeted delivery

Indexed keywords

CANCER; LIPID NANOPARTICLE; MESOPOROUS SILICA NANOPARTICLE; PEPTIDE LIGAND; SMALL INTERFERING RNA; SUPPORTED LIPID BILAYERS; TARGETED DELIVERY;

CELL DEATH; GENE EXPRESSION; GENE THERAPY; NANOPARTICLES; OLIGONUCLEOTIDES; PEPTIDES; RNA;

LIPID BILAYERS;

NANOPARTICLE; PEPTIDE; SILICON DIOXIDE; SMALL INTERFERING RNA;

ANIMAL; APOPTOSIS; ARTICLE; CELL LINE; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; GENE SILENCING; GENETIC TRANSFECTION; GENETICS; HUMAN; LIPID BILAYER; METABOLISM; METHODOLOGY; POROSITY;

ANIMALS; APOPTOSIS; CELL LINE; CELL PROLIFERATION; GENE SILENCING; HUMANS; LIPID BILAYERS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; NANOPARTICLES; PEPTIDES; POROSITY; RNA, SMALL INTERFERING; SILICON DIOXIDE; TRANSFECTION;

EID: 84859127335     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn204102q     Document Type: Article

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