메뉴 건너뛰기




Volumn 11, Issue 12, 2015, Pages 2247-2258

GADD45A inhibits autophagy by regulating the interaction between BECN1 and PIK3C3

Author keywords

Autophagy; BECN1; GADD45A; PIK3C3; Tumor

Indexed keywords

BECLIN 1; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; MICROTUBULE ASSOCIATED PROTEIN 2; PHOSPHATIDYLINOSITOL 3 KINASE; APOPTOSIS REGULATORY PROTEIN; BECN1 PROTEIN, MOUSE; CELL CYCLE PROTEIN; GADD45A PROTEIN, MOUSE; NUCLEAR PROTEIN; PIK3C3 PROTEIN, MOUSE;

EID: 84964277228     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.1080/15548627.2015.1112484     Document Type: Article
Times cited : (24)

References (49)
  • 1
    • 50249084987 scopus 로고    scopus 로고
    • Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum
    • 18725538
    • Axe EL, Walker SA, Manifava M, Chandra P, Roderick HL, Habermann A, Griffiths G, Ktistakis NT. Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. J Cell Biol 2008; 182: 685-701; PMID: 18725538; http://dx.doi.org/10.1083/jcb.200803137
    • (2008) J Cell Biol , vol.182 , pp. 685-701
    • Axe, E.L.1    Walker, S.A.2    Manifava, M.3    Chandra, P.4    Roderick, H.L.5    Habermann, A.6    Griffiths, G.7    Ktistakis, N.T.8
  • 2
    • 70349919804 scopus 로고    scopus 로고
    • Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes
    • 19797076
    • Simonsen A, Tooze SA. Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes. J Cell Biol 2009; 186: 773-82; PMID: 19797076; http://dx.doi.org/10.1083/jcb.200907014
    • (2009) J Cell Biol , vol.186 , pp. 773-782
    • Simonsen, A.1    Tooze, S.A.2
  • 3
    • 36249025723 scopus 로고    scopus 로고
    • Autophagy: Process and function
    • 18006683
    • Mizushima N. Autophagy: process and function. Genes Dev 2007; 21: 2861-73; PMID: 18006683; http://dx. doi.org/10.1101/gad.1599207
    • (2007) Genes Dev , vol.21 , pp. 2861-2873
    • Mizushima, N.1
  • 4
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • 18191218
    • Levine B, Kroemer G. Autophagy in the pathogenesis of disease. Cell 2008; 132: 27-42; PMID: 18191218; http://dx.doi.org/10.1016/j.cell.2007.12.018
    • (2008) Cell , vol.132 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 5
    • 34147193472 scopus 로고    scopus 로고
    • Cell biology: Autophagy and cancer
    • 17429391
    • Levine B. Cell biology: autophagy and cancer. Nature 2007; 446: 745-7; PMID: 17429391; http://dx.doi.org/10.1038/446745a
    • (2007) Nature , vol.446 , pp. 745-747
    • Levine, B.1
  • 6
    • 80051668850 scopus 로고    scopus 로고
    • The dual role of autophagy in cancer
    • 21498118
    • Eskelinen EL. The dual role of autophagy in cancer. Curr Opin Pharmacol 2011; 11: 294-300; PMID: 21498118; http://dx.doi.org/10.1016/j.coph.2011.03.009
    • (2011) Curr Opin Pharmacol , vol.11 , pp. 294-300
    • Eskelinen, E.L.1
  • 7
    • 0000906170 scopus 로고    scopus 로고
    • Induction of autophagy and inhibition of tumorigenesis by beclin 1
    • 10604474
    • Liang XH, Jackson S, Seaman M, Brown K, Kempkes B, Hibshoosh H, Levine B. Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature 1999; 402: 672-6; PMID: 10604474; http://dx.doi.org/10.1038/45257
    • (1999) Nature , vol.402 , pp. 672-676
    • Liang, X.H.1    Jackson, S.2    Seaman, M.3    Brown, K.4    Kempkes, B.5    Hibshoosh, H.6    Levine, B.7
  • 8
    • 0345166111 scopus 로고    scopus 로고
    • Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
    • 14657337
    • Yue Z, Jin S, Yang C, Levine AJ, Heintz N. Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc Natl Acad Sci U S A 2003; 100: 15077-82; PMID: 14657337; http://dx.doi.org/10.1073/pnas.2436255100
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 15077-15082
    • Yue, Z.1    Jin, S.2    Yang, C.3    Levine, A.J.4    Heintz, N.5
  • 10
    • 79956003662 scopus 로고    scopus 로고
    • Measurements of tumor cell autophagy predict invasiveness, resistance to chemotherapy, and survival in melanoma
    • 21325076
    • Ma XH, Piao S, Wang D, McAfee QW, Nathanson KL, Lum JJ, Li LZ, Amaravadi RK. Measurements of tumor cell autophagy predict invasiveness, resistance to chemotherapy, and survival in melanoma. Clin Cancer Res 2011; 17: 3478-89; PMID: 21325076; http://dx. doi.org/10.1158/1078-0432.CCR-10-2372
    • (2011) Clin Cancer Res , vol.17 , pp. 3478-3489
    • Ma, X.H.1    Piao, S.2    Wang, D.3    McAfee, Q.W.4    Nathanson, K.L.5    Lum, J.J.6    Li, L.Z.7    Amaravadi, R.K.8
  • 13
    • 0001488499 scopus 로고    scopus 로고
    • Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein
    • 9765397
    • Liang XH, Kleeman LK, Jiang HH, Gordon G, Goldman JE, Berry G, Herman B, Levine B. Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein. J Virol 1998; 72: 8586-96; PMID: 9765397
    • (1998) J Virol , vol.72 , pp. 8586-8596
    • Liang, X.H.1    Kleeman, L.K.2    Jiang, H.H.3    Gordon, G.4    Goldman, J.E.5    Berry, G.6    Herman, B.7    Levine, B.8
  • 15
    • 33645512801 scopus 로고    scopus 로고
    • Bcl-2 inhibition of autophagy: A new route to cancer?
    • 16540632
    • Pattingre S, Levine B. Bcl-2 inhibition of autophagy: a new route to cancer? Cancer Res 2006; 66: 2885-8; PMID: 16540632; http://dx.doi.org/10.1158/0008-5472.CAN-05-4412
    • (2006) Cancer Res , vol.66 , pp. 2885-2888
    • Pattingre, S.1    Levine, B.2
  • 16
    • 34247186472 scopus 로고    scopus 로고
    • Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4
    • 17347651
    • Scherz-Shouval R, Shvets E, Fass E, Shorer H, Gil L, Elazar Z. Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4. EMBO J 2007; 26: 1749-60; PMID: 17347651; http:// dx.doi.org/10.1038/sj.emboj.7601623
    • (2007) EMBO J , vol.26 , pp. 1749-1760
    • Scherz-Shouval, R.1    Shvets, E.2    Fass, E.3    Shorer, H.4    Gil, L.5    Elazar, Z.6
  • 17
    • 34548188741 scopus 로고    scopus 로고
    • Selfeating and self-killing: Crosstalk between autophagy and apoptosis
    • 17717517
    • Maiuri MC, Zalckvar E, Kimchi A, Kroemer G. Selfeating and self-killing: crosstalk between autophagy and apoptosis. Nat Rev Mol Cell Biol 2007; 8: 741-52; PMID: 17717517; http://dx.doi.org/10.1038/nrm2239
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 741-752
    • Maiuri, M.C.1    Zalckvar, E.2    Kimchi, A.3    Kroemer, G.4
  • 18
    • 44649101436 scopus 로고    scopus 로고
    • p53: The Janus of autophagy?
    • 18521069
    • Levine B, Abrams J. p53: The Janus of autophagy? Nat Cell Biol 2008; 10: 637-9; PMID: 18521069; http://dx. doi.org/10.1038/ncb0608-637
    • (2008) Nat Cell Biol , vol.10 , pp. 637-639
    • Levine, B.1    Abrams, J.2
  • 20
    • 20444363122 scopus 로고    scopus 로고
    • The coordinate regulation of the p53 and mTOR pathways in cells
    • 15928081
    • Feng Z, Zhang H, Levine AJ, Jin S. The coordinate regulation of the p53 and mTOR pathways in cells. Proc Natl Acad Sci U S A 2005; 102: 8204-9; PMID: 15928081; http://dx.doi.org/10.1073/pnas.0502857102
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 8204-8209
    • Feng, Z.1    Zhang, H.2    Levine, A.J.3    Jin, S.4
  • 21
    • 39049144417 scopus 로고    scopus 로고
    • p53-Dependent and p53-independent activation of autophagy by ARF
    • 18199527
    • Abida WM, Gu W. p53-Dependent and p53-independent activation of autophagy by ARF. Cancer Res 2008; 68: 352-7; PMID: 18199527; http://dx.doi.org/10.1158/0008-5472.CAN-07-2069
    • (2008) Cancer Res , vol.68 , pp. 352-357
    • Abida, W.M.1    Gu, W.2
  • 23
    • 0038556509 scopus 로고
    • DNA damage- inducible transcripts in mammalian cells
    • 3194391
    • Fornace AJ, Jr., Alamo I, Jr., Hollander MC. DNA damage- inducible transcripts in mammalian cells. Proc Natl Acad Sci U S A 1988; 85: 8800-4; PMID: 3194391; http://dx.doi.org/10.1073/pnas.85.23.8800
    • (1988) Proc Natl Acad Sci U S A , vol.85 , pp. 8800-8804
    • Fornace, A.J.1    Alamo, I.2    Hollander, M.C.3
  • 24
    • 0026021668 scopus 로고
    • Induction by ionizing radiation of the gadd45 gene in cultured human cells: Lack of mediation by protein kinase C
    • 1990262
    • Papathanasiou MA, Kerr NC, Robbins JH, McBride OW, Alamo I, Jr., Barrett SF, Hickson ID, Fornace AJ, Jr. Induction by ionizing radiation of the gadd45 gene in cultured human cells: lack of mediation by protein kinase C. Mol Cell Biol 1991; 11: 1009-16; PMID: 1990262; http://dx.doi.org/10.1128/MCB.11.2.1009
    • (1991) Mol Cell Biol , vol.11 , pp. 1009-1016
    • Papathanasiou, M.A.1    Kerr, N.C.2    Robbins, J.H.3    McBride, O.W.4    Alamo, I.5    Barrett, S.F.6    Hickson, I.D.7    Fornace Jr, A.J.8
  • 25
    • 0026496885 scopus 로고
    • A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
    • 1423616
    • Kastan MB, Zhan Q, el-Deiry WS, Carrier F, Jacks T, Walsh WV, Plunkett BS, Vogelstein B, Fornace AJ, Jr. A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia. Cell 1992; 71: 587-97; PMID: 1423616; http://dx.doi. org/10.1016/0092-8674(92)90593-2
    • (1992) Cell , vol.71 , pp. 587-597
    • Kastan, M.B.1    Zhan, Q.2    el-Deiry, W.S.3    Carrier, F.4    Jacks, T.5    Walsh, W.V.6    Plunkett, B.S.7    Vogelstein, B.8    Fornace Jr, A.J.9
  • 26
    • 0028175990 scopus 로고
    • The p53- dependent gamma-ray response of GADD45
    • 8168107
    • Zhan Q, Bae I, Kastan MB, Fornace AJ, Jr. The p53- dependent gamma-ray response of GADD45. Cancer Res 1994; 54: 2755-60; PMID: 8168107
    • (1994) Cancer Res , vol.54 , pp. 2755-2760
    • Zhan, Q.1    Bae, I.2    Kastan, M.B.3    Fornace Jr, A.J.4
  • 27
    • 0031946364 scopus 로고    scopus 로고
    • Tumor suppressor p53 can participate in transcriptional induction of the GADD45 promoter in the absence of direct DNA binding
    • 9566896
    • Zhan Q, Chen IT, Antinore MJ, Fornace AJ, Jr. Tumor suppressor p53 can participate in transcriptional induction of the GADD45 promoter in the absence of direct DNA binding. Mol Cell Biol 1998; 18: 2768-78; PMID: 9566896; http://dx.doi.org/10.1128/MCB.18.5.2768
    • (1998) Mol Cell Biol , vol.18 , pp. 2768-2778
    • Zhan, Q.1    Chen, I.T.2    Antinore, M.J.3    Fornace Jr, A.J.4
  • 28
    • 0029960486 scopus 로고    scopus 로고
    • Abrogation of p53 function affects gadd gene responses to DNA basedamaging agents and starvation
    • 8892753
    • Zhan Q, Fan S, Smith ML, Bae I, Yu K, Alamo I, Jr., O’Connor PM, Fornace AJ, Jr. Abrogation of p53 function affects gadd gene responses to DNA basedamaging agents and starvation. DNA Cell Biol 1996; 15: 805-15; PMID: 8892753; http://dx.doi.org/10.1089/dna.1996.15.805
    • (1996) DNA Cell Biol , vol.15 , pp. 805-815
    • Zhan, Q.1    Fan, S.2    Smith, M.L.3    Bae, I.4    Yu, K.5    Alamo, I.6    O’Connor, P.M.7    Fornace Jr, A.J.8
  • 29
    • 0037069924 scopus 로고    scopus 로고
    • GADD45-induced cell cycle G2-M arrest associates with altered subcellular distribution of cyclin B1 and is independent of p38 kinase activity
    • 12483522
    • Jin S, Tong T, Fan W, Fan F, Antinore MJ, Zhu X, Mazzacurati L, Li X, Petrik KL, Rajasekaran B, et al. GADD45-induced cell cycle G2-M arrest associates with altered subcellular distribution of cyclin B1 and is independent of p38 kinase activity. Oncogene 2002; 21: 8696-704; PMID: 12483522; http://dx.doi.org/10.1038/sj.onc.1206034
    • (2002) Oncogene , vol.21 , pp. 8696-8704
    • Jin, S.1    Tong, T.2    Fan, W.3    Fan, F.4    Antinore, M.J.5    Zhu, X.6    Mazzacurati, L.7    Li, X.8    Petrik, K.L.9    Rajasekaran, B.10
  • 30
    • 21044444012 scopus 로고    scopus 로고
    • Gadd45a expression induces Bim dissociation from the cytoskeleton and translocation to mitochondria
    • 15899854
    • Tong T, Ji J, Jin S, Li X, Fan W, Song Y, Wang M, Liu Z, Wu M, Zhan Q. Gadd45a expression induces Bim dissociation from the cytoskeleton and translocation to mitochondria. Mol Cell Biol 2005; 25: 4488-500; PMID: 15899854; http://dx.doi.org/10.1128/ MCB.25.11.4488-4500.2005
    • (2005) Mol Cell Biol , vol.25 , pp. 4488-4500
    • Tong, T.1    Ji, J.2    Jin, S.3    Li, X.4    Fan, W.5    Song, Y.6    Wang, M.7    Liu, Z.8    Wu, M.9    Zhan, Q.10
  • 32
    • 84874786609 scopus 로고    scopus 로고
    • Gadd45a suppresses tumor angiogenesis via inhibition of the mTOR/ STAT3 protein pathway
    • 23329839
    • Yang F, Zhang W, Li D, Zhan Q. Gadd45a suppresses tumor angiogenesis via inhibition of the mTOR/ STAT3 protein pathway. J Biol Chem 2013; 288: 6552-60; PMID: 23329839; http://dx.doi.org/10.1074/jbc.M112.418335
    • (2013) J Biol Chem , vol.288 , pp. 6552-6560
    • Yang, F.1    Zhang, W.2    Li, D.3    Zhan, Q.4
  • 33
    • 17844395749 scopus 로고    scopus 로고
    • Analysis of methylation-sensitive transcriptome identifies GADD45a as a frequently methylated gene in breast cancer
    • 15735726
    • Wang W, Huper G, Guo Y, Murphy SK, Olson JA, Jr., Marks JR. Analysis of methylation-sensitive transcriptome identifies GADD45a as a frequently methylated gene in breast cancer. Oncogene 2005; 24: 2705-14; PMID: 15735726; http://dx.doi.org/10.1038/sj. onc.1208464
    • (2005) Oncogene , vol.24 , pp. 2705-2714
    • Wang, W.1    Huper, G.2    Guo, Y.3    Murphy, S.K.4    Olson, J.A.5    Marks, J.R.6
  • 34
    • 0036023416 scopus 로고    scopus 로고
    • Clinicopathological significance of abnormalities in Gadd45 expression and its relationship to p53 in human pancreatic cancer
    • 12171884
    • Yamasawa K, Nio Y, Dong M, Yamaguchi K, Itakura M. Clinicopathological significance of abnormalities in Gadd45 expression and its relationship to p53 in human pancreatic cancer. Clin Cancer Res 2002; 8: 2563-9; PMID: 12171884
    • (2002) Clin Cancer Res , vol.8 , pp. 2563-2569
    • Yamasawa, K.1    Nio, Y.2    Dong, M.3    Yamaguchi, K.4    Itakura, M.5
  • 35
    • 60549108922 scopus 로고    scopus 로고
    • Methylationmediated repression of GADD45alpha in prostate cancer and its role as a potential therapeutic target
    • 19190346
    • Ramachandran K, Gopisetty G, Gordian E, Navarro L, Hader C, Reis IM, Schulz WA, Singal R. Methylationmediated repression of GADD45alpha in prostate cancer and its role as a potential therapeutic target. Cancer Res 2009; 69: 1527-35; PMID: 19190346; http://dx. doi.org/10.1158/0008-5472.CAN-08-3609
    • (2009) Cancer Res , vol.69 , pp. 1527-1535
    • Ramachandran, K.1    Gopisetty, G.2    Gordian, E.3    Navarro, L.4    Hader, C.5    Reis, I.M.6    Schulz, W.A.7    Singal, R.8
  • 36
    • 0035866787 scopus 로고    scopus 로고
    • Dimethylbenzanthracene carcinogenesis in Gadd45a-null mice is associated with decreased DNA repair and increased mutation frequency
    • 11289119
    • Hollander MC, Kovalsky O, Salvador JM, Kim KE, Patterson AD, Haines DC, Fornace AJ, Jr. Dimethylbenzanthracene carcinogenesis in Gadd45a-null mice is associated with decreased DNA repair and increased mutation frequency. Cancer Res 2001; 61: 2487-91; PMID: 11289119
    • (2001) Cancer Res , vol.61 , pp. 2487-2491
    • Hollander, M.C.1    Kovalsky, O.2    Salvador, J.M.3    Kim, K.E.4    Patterson, A.D.5    Haines, D.C.6    Fornace Jr, A.J.7
  • 38
    • 72549095406 scopus 로고    scopus 로고
    • Regulation mechanisms and signaling pathways of autophagy
    • 19653858
    • He C, Klionsky DJ. Regulation mechanisms and signaling pathways of autophagy. Annu Rev Genet 2009; 43: 67-93; PMID: 19653858; http://dx.doi.org/10.1146/annurev-genet-102808-114910
    • (2009) Annu Rev Genet , vol.43 , pp. 67-93
    • He, C.1    Klionsky, D.J.2
  • 39
    • 84869475871 scopus 로고    scopus 로고
    • Activation of the macroautophagic system in scrapie-infected experimental animals and human genetic prion diseases
    • 22874564
    • Xu Y, Tian C, Wang SB, Xie WL, Guo Y, Zhang J, Shi Q, Chen C, Dong XP. Activation of the macroautophagic system in scrapie-infected experimental animals and human genetic prion diseases. Autophagy 2012; 8: 1604-20; PMID: 22874564; http://dx.doi.org/10.4161/auto.21482
    • (2012) Autophagy , vol.8 , pp. 1604-1620
    • Xu, Y.1    Tian, C.2    Wang, S.B.3    Xie, W.L.4    Guo, Y.5    Zhang, J.6    Shi, Q.7    Chen, C.8    Dong, X.P.9
  • 40
    • 84903309911 scopus 로고    scopus 로고
    • NRBF2 regulates macroautophagy as a component of Vps34 Complex I
    • 24785657
    • Cao Y, Wang Y, Abi Saab WF, Yang F, Pessin JE, Backer JM. NRBF2 regulates macroautophagy as a component of Vps34 Complex I. Biochem J 2014; 461: 315-22; PMID: 24785657; http://dx.doi.org/10.1042/BJ20140515
    • (2014) Biochem J , vol.461 , pp. 315-322
    • Cao, Y.1    Wang, Y.2    Abi Saab, W.F.3    Yang, F.4    Pessin, J.E.5    Backer, J.M.6
  • 41
    • 59249089394 scopus 로고    scopus 로고
    • Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG
    • 18843052
    • Itakura E, Kishi C, Inoue K, Mizushima N. Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG. Mol Biol Cell 2008; 19: 5360-72; PMID: 18843052; http://dx. doi.org/10.1091/mbc.E08-01-0080
    • (2008) Mol Biol Cell , vol.19 , pp. 5360-5372
    • Itakura, E.1    Kishi, C.2    Inoue, K.3    Mizushima, N.4
  • 42
    • 77953543377 scopus 로고    scopus 로고
    • The Beclin 1-VPS34 complex-at the crossroads of autophagy and beyond
    • 20356743
    • Funderburk SF, Wang QJ, Yue Z. The Beclin 1-VPS34 complex-at the crossroads of autophagy and beyond. Trends Cell Biol 2010; 20: 355-62; PMID: 20356743; http://dx.doi.org/10.1016/j.tcb.2010.03.002
    • (2010) Trends Cell Biol , vol.20 , pp. 355-362
    • Funderburk, S.F.1    Wang, Q.J.2    Yue, Z.3
  • 45
    • 84877340860 scopus 로고    scopus 로고
    • Inhibition of autophagy through MAPK14-mediated phosphorylation of ATG5
    • 23235332
    • Hocker R, Walker A, Schmitz I. Inhibition of autophagy through MAPK14-mediated phosphorylation of ATG5. Autophagy 2013; 9: 426-8; PMID: 23235332; http://dx.doi.org/10.4161/auto.22924
    • (2013) Autophagy , vol.9 , pp. 426-428
    • Hocker, R.1    Walker, A.2    Schmitz, I.3
  • 47
    • 0035902115 scopus 로고    scopus 로고
    • Proliferation, cell cycle and apoptosis in cancer
    • 11357141
    • Evan GI, Vousden KH. Proliferation, cell cycle and apoptosis in cancer. Nature 2001; 411: 342-8; PMID: 11357141; http://dx.doi.org/10.1038/35077213
    • (2001) Nature , vol.411 , pp. 342-348
    • Evan, G.I.1    Vousden, K.H.2
  • 48
    • 0028329172 scopus 로고
    • Apoptosis. Its significance in cancer and cancer therapy
    • 8156506
    • Kerr JF, Winterford CM, Harmon BV. Apoptosis. Its significance in cancer and cancer therapy. Cancer 1994; 73: 2013-26; PMID: 8156506; http://dx.doi.org/10.1002/1097-0142(19940415)73: 8%3c2013:: AIDCNCR2820730802%3e3.0.CO;2-J
    • (1994) Cancer , vol.73 , pp. 2013-2026
    • Kerr, J.F.1    Winterford, C.M.2    Harmon, B.V.3
  • 49
    • 25444440875 scopus 로고    scopus 로고
    • The role of autophagy in cancer development and response to therapy
    • 16148885
    • Kondo Y, Kanzawa T, Sawaya R, Kondo S. The role of autophagy in cancer development and response to therapy. Nat Rev Cancer 2005; 5: 726-34; PMID: 16148885; http://dx.doi.org/10.1038/nrc1692
    • (2005) Nat Rev Cancer , vol.5 , pp. 726-734
    • Kondo, Y.1    Kanzawa, T.2    Sawaya, R.3    Kondo, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.