메뉴 건너뛰기




Volumn 461, Issue 2, 2014, Pages 315-322

NRBF2 regulates macroautophagy as a component of Vps34 complex I

Author keywords

Autophagy; Human vacuolar protein sorting 34 (hVps34); Macroautophagy; Mass spectrometry; Nuclear receptor binding factor 2 (NRBF2); Vacuolar protein sorting 15 (Vps15); Vacuolar protein sorting 34 (Vps34)

Indexed keywords

BECLIN 1; BINDING PROTEIN; GREEN FLUORESCENT PROTEIN; NUCLEAR RECEPTOR BINDING FACTOR 2; PHOSPHATIDYLETHANOLAMINE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P62; PROTEIN SERINE THREONINE KINASE VPS15; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE); UNCLASSIFIED DRUG;

EID: 84903309911     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20140515     Document Type: Article
Times cited : (61)

References (35)
  • 1
    • 84892569830 scopus 로고    scopus 로고
    • An overview of autophagy: Morphology, mechanism, and regulation
    • CrossRef PubMed
    • Parzych, K. R. and Klionsky, D. J. (2013) An overview of autophagy: morphology, mechanism, and regulation. Antioxid. Redox Signal. 20, 460-473 CrossRef PubMed
    • (2013) Antioxid. Redox Signal. , vol.20 , pp. 460-473
    • Parzych, K.R.1    Klionsky, D.J.2
  • 2
    • 84878943669 scopus 로고    scopus 로고
    • The mechanism and physiological function of macroautophagy
    • CrossRef PubMed
    • Klionsky, D. J. and Codogno, P. (2013) The mechanism and physiological function of macroautophagy. J. Innate Immun. 5, 427-433 CrossRef PubMed
    • (2013) J. Innate Immun. , vol.5 , pp. 427-433
    • Klionsky, D.J.1    Codogno, P.2
  • 3
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • CrossRef PubMed
    • Levine, B. and Kroemer, G. (2008) Autophagy in the pathogenesis of disease. Cell 132, 27-42 CrossRef PubMed
    • (2008) Cell , vol.132 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 4
    • 34548700796 scopus 로고    scopus 로고
    • Unveiling the roles of autophagy in innate and adaptive immunity
    • DOI 10.1038/nri2161, PII NRI2161
    • Levine, B. and Deretic, V. (2007) Unveiling the roles of autophagy in innate and adaptive immunity. Nat. Rev. Immunol. 7, 767-777 CrossRef PubMed (Pubitemid 47480305)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.10 , pp. 767-777
    • Levine, B.1    Deretic, V.2
  • 5
    • 39849109338 scopus 로고    scopus 로고
    • Autophagy fights disease through cellular self-digestion
    • DOI 10.1038/nature06639, PII NATURE06639
    • Mizushima, N., Levine, B., Cuervo, A. M. and Klionsky, D. J. (2008) Autophagy fights disease through cellular self-digestion. Nature 451, 1069-1075 CrossRef PubMed (Pubitemid 351317450)
    • (2008) Nature , vol.451 , Issue.7182 , pp. 1069-1075
    • Mizushima, N.1    Levine, B.2    Cuervo, A.M.3    Klionsky, D.J.4
  • 7
    • 84891746273 scopus 로고    scopus 로고
    • Recent insights on the putative role of autophagy in autoimmune diseases
    • CrossRef PubMed
    • Gianchecchi, E., Delfino, D. V. and Fierabracci, A. (2013) Recent insights on the putative role of autophagy in autoimmune diseases. Autoimmun. Rev. 13, 231-241 CrossRef PubMed
    • (2013) Autoimmun. Rev. , vol.13 , pp. 231-241
    • Gianchecchi, E.1    Delfino, D.V.2    Fierabracci, A.3
  • 8
    • 84896465806 scopus 로고    scopus 로고
    • Neuronal autophagy and neurodevelopmental disorders
    • CrossRef PubMed
    • Lee, K. M., Hwang, S. K. and Lee, J. A. (2013) Neuronal autophagy and neurodevelopmental disorders. Exp. Neurobiol. 22, 133-142 CrossRef PubMed
    • (2013) Exp. Neurobiol. , vol.22 , pp. 133-142
    • Lee, K.M.1    Hwang, S.K.2    Lee, J.A.3
  • 9
    • 84890087641 scopus 로고    scopus 로고
    • Autophagy and metabolic changes in obesity-related chronic kidney disease
    • CrossRef
    • Satriano, J. and Sharma, K. (2013) Autophagy and metabolic changes in obesity-related chronic kidney disease. Nephrol. Dial. Transplant. 28, iv29-iv36 CrossRef
    • (2013) Nephrol. Dial. Transplant. , vol.28
    • Satriano, J.1    Sharma, K.2
  • 10
  • 11
    • 84876796439 scopus 로고    scopus 로고
    • Inflammation, autophagy, and obesity: Common features in the pathogenesis of pancreatitis and pancreatic cancer
    • CrossRef PubMed
    • Gukovsky, I., Li, N., Todoric, J., Gukovskaya, A. and Karin, M. (2013) Inflammation, autophagy, and obesity: common features in the pathogenesis of pancreatitis and pancreatic cancer. Gastroenterology 144, 1199-1209 CrossRef PubMed
    • (2013) Gastroenterology , vol.144 , pp. 1199-1209
    • Gukovsky, I.1    Li, N.2    Todoric, J.3    Gukovskaya, A.4    Karin, M.5
  • 12
    • 84877905545 scopus 로고    scopus 로고
    • Autophagy: A targetable linchpin of cancer cell metabolism
    • CrossRef PubMed
    • Leone, R. D. and Amaravadi, R. K. (2013) Autophagy: a targetable linchpin of cancer cell metabolism. Trends Endocrinol. Metab. 24, 209-217 CrossRef PubMed
    • (2013) Trends Endocrinol. Metab. , vol.24 , pp. 209-217
    • Leone, R.D.1    Amaravadi, R.K.2
  • 13
    • 84884819157 scopus 로고    scopus 로고
    • Autophagosome formation: The role of ULK1 and Beclin1-PI3KC3 complexes in setting the stage
    • CrossRef PubMed
    • Wirth, M., Joachim, J. and Tooze, S. A. (2013) Autophagosome formation: the role of ULK1 and Beclin1-PI3KC3 complexes in setting the stage. Semin. Cancer Biol. 23, 301-309 CrossRef PubMed
    • (2013) Semin. Cancer Biol. , vol.23 , pp. 301-309
    • Wirth, M.1    Joachim, J.2    Tooze, S.A.3
  • 14
    • 39749141485 scopus 로고    scopus 로고
    • The regulation and function of Class III PI3Ks: Novel roles for Vps34
    • CrossRef PubMed
    • Backer, J. M. (2008) The regulation and function of Class III PI3Ks: novel roles for Vps34. Biochem. J. 410, 1-17 CrossRef PubMed
    • (2008) Biochem. J. , vol.410 , pp. 1-17
    • Backer, J.M.1
  • 15
    • 70349919804 scopus 로고    scopus 로고
    • Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes
    • CrossRef PubMed
    • Simonsen, A. and Tooze, S. A. (2009) Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes. J. Cell Biol. 186, 773-782 CrossRef PubMed
    • (2009) J. Cell Biol. , vol.186 , pp. 773-782
    • Simonsen, A.1    Tooze, S.A.2
  • 16
    • 54249096642 scopus 로고    scopus 로고
    • Sequential actions of myotubularin lipid phosphatases regulate endosomal PI(3)P and growth factor receptor trafficking
    • CrossRef PubMed
    • Cao, C., Backer, J. M., Laporte, J., Bedrick, E. J. and Wandinger-Ness, A. (2008) Sequential actions of myotubularin lipid phosphatases regulate endosomal PI(3)P and growth factor receptor trafficking. Mol. Biol. Cell 19, 3334-3346 CrossRef PubMed
    • (2008) Mol. Biol. Cell , vol.19 , pp. 3334-3346
    • Cao, C.1    Backer, J.M.2    Laporte, J.3    Bedrick, E.J.4    Wandinger-Ness, A.5
  • 17
    • 34447543013 scopus 로고    scopus 로고
    • Myotubularin lipid phosphatase binds the hVPS15/hVPS34 lipid kinase complex on endosomes
    • DOI 10.1111/j.1600-0854.2007.00586.x
    • Cao, C., Laporte, J., Backer, J. M., Wandinger-Ness, A. and Stein, M. P. (2007) Myotubularin lipid phosphatase binds the hVPS15/hVPS34 lipid kinase complex on endosomes. Traffic 8, 1052-1067 CrossRef PubMed (Pubitemid 47074038)
    • (2007) Traffic , vol.8 , Issue.8 , pp. 1052-1067
    • Cao, C.1    Laporte, J.2    Backer, J.M.3    Wandinger-Ness, A.4    Stein, M.-P.5
  • 18
    • 0036300306 scopus 로고    scopus 로고
    • Role of Rab5 in the recruitment of hVps34/p150 to the early endosome
    • DOI 10.1034/j.1600-0854.2002.30605.x
    • Murray, J. T., Panaretou, C., Stenmark, H., Miaczynska, M. and Backer, J. M. (2002) Role of Rab5 in the recruitment of hVps34/p150 to the early endosome. Traffic 3, 416-427 CrossRef PubMed (Pubitemid 34746409)
    • (2002) Traffic , vol.3 , Issue.6 , pp. 416-427
    • Murray, J.T.1    Panaretou, C.2    Stenmark, H.3    Miaczynska, M.4    Backer, J.M.5
  • 20
    • 33745685061 scopus 로고    scopus 로고
    • Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein α subunit at the endosome
    • CrossRef PubMed
    • Slessareva, J. E., Routt, S. M., Temple, B., Bankaitis, V. A. and Dohlman, H. G. (2006) Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein α subunit at the endosome. Cell 126, 191-203 CrossRef PubMed
    • (2006) Cell , vol.126 , pp. 191-203
    • Slessareva, J.E.1    Routt, S.M.2    Temple, B.3    Bankaitis, V.A.4    Dohlman, H.G.5
  • 21
    • 77954237882 scopus 로고    scopus 로고
    • Network organization of the human autophagy system
    • CrossRef PubMed
    • Behrends, C., Sowa, M. E., Gygi, S. P. and Harper, J. W. (2010) Network organization of the human autophagy system. Nature 466, 68-76 CrossRef PubMed
    • (2010) Nature , vol.466 , pp. 68-76
    • Behrends, C.1    Sowa, M.E.2    Gygi, S.P.3    Harper, J.W.4
  • 22
    • 0033972940 scopus 로고    scopus 로고
    • Nuclear receptor binding factor-2 (NRBF-2), a possible gene activator protein interacting with nuclear hormone receptors
    • DOI 10.1016/S0167-4781(99)00244-4, PII S0167478199002444
    • Yasumo, H., Masuda, N., Furusawa, T., Tsukamoto, T., Sadano, H. and Osumi, T. (2000) Nuclear receptor binding factor-2 (NRBF-2), a possible gene activator protein interacting with nuclear hormone receptors. Biochim. Biophys. Acta 1490, 189-197 CrossRef PubMed (Pubitemid 30070152)
    • (2000) Biochimica et Biophysica Acta - Gene Structure and Expression , vol.1490 , Issue.1-2 , pp. 189-197
    • Yasumo, H.1    Masuda, N.2    Furusawa, T.3    Tsukamoto, T.4    Sadano, H.5    Osumi, T.6
  • 23
    • 9744273192 scopus 로고    scopus 로고
    • Isolation and functional analysis of a keratinocyte-derived, ligand-regulated nuclear receptor comodulator
    • DOI 10.1111/j.0022-202X.2004.23424.x
    • Flores, A. M., Li, L. and Aneskievich, B. J. (2004) Isolation and functional analysis of a keratinocyte-derived, ligand-regulated nuclear receptor comodulator. J. Invest. Dermatol. 123, 1092-1101 CrossRef PubMed (Pubitemid 39586832)
    • (2004) Journal of Investigative Dermatology , vol.123 , Issue.6 , pp. 1092-1101
    • Flores, A.M.1    Li, L.2    Aneskievich, B.J.3
  • 24
    • 0032517624 scopus 로고    scopus 로고
    • Distinct roles for the p110alpha and hVPS34 phosphatidylinositol 3'- kinases in vesicular trafficking, regulation of the actin cytoskeleton, and mitogenesis
    • DOI 10.1083/jcb.143.6.1647
    • Siddhanta, U., McIlroy, J., Shah, A., Zhang, Y. T. and Backer, J. M. (1998) Distinct roles for the p110a and hVPS34 phosphatidylinositol 3′-kinases in vesicular trafficking, regulation of the actin cytoskeleton, and mitogenesis. J. Cell Biol. 143, 1647-1659 CrossRef PubMed (Pubitemid 29006509)
    • (1998) Journal of Cell Biology , vol.143 , Issue.6 , pp. 1647-1659
    • Siddhanta, U.1    McIlroy, J.2    Shah, A.3    Zhang, Y.4    Backer, J.M.5
  • 25
    • 59849113021 scopus 로고    scopus 로고
    • 2+ /CaM, is required for the activity and regulation of hVps34 in mammalian cells
    • CrossRef PubMed
    • 2+ /CaM, is required for the activity and regulation of hVps34 in mammalian cells. Biochem. J. 417, 747-755 CrossRef PubMed
    • (2009) Biochem. J. , vol.417 , pp. 747-755
    • Yan, Y.1    Flinn, R.J.2    Wu, H.3    Schnur, R.S.4    Backer, J.M.5
  • 27
    • 0037016749 scopus 로고    scopus 로고
    • The C terminus of the Vps34p phosphoinositide 3-kinase is necessary and sufficient for the interaction with the Vps15p protein kinase
    • DOI 10.1074/jbc.M109263200
    • Budovskaya, Y. V., Hama, H., DeWald, D. and Herman, P. K. (2002) The C-terminus of the Vps34p PI 3-kinase is necessary and sufficient for the interaction with the Vps15p protein kinase. J. Biol. Chem. 277, 287-294 CrossRef PubMed (Pubitemid 34952057)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.1 , pp. 287-294
    • Budovskaya, Y.V.1    Hama, H.2    Dewald, D.B.3    Herman, P.K.4
  • 28
    • 46449120732 scopus 로고    scopus 로고
    • Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking
    • DOI 10.1038/ncb1740, PII NCB1740
    • Liang, C., Lee, J. S., Inn, K. S., Gack, M. U., Li, Q., Roberts, E. A., Vergne, I., Deretic, V., Feng, P., Akazawa, C. and Jung, J. U. (2008) Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking. Nat. Cell Biol. 10, 776-787 CrossRef PubMed (Pubitemid 351927707)
    • (2008) Nature Cell Biology , vol.10 , Issue.7 , pp. 776-787
    • Liang, C.1    Lee, J.-S.2    Inn, K.-S.3    Gack, M.U.4    Li, Q.5    Roberts, E.A.6    Vergne, I.7    Deretic, V.8    Feng, P.9    Akazawa, C.10    Jung, J.U.11
  • 29
    • 50249089984 scopus 로고    scopus 로고
    • Beyond autophagy: The role of UVRAG in membrane trafficking
    • PubMed
    • Liang, C., Sir, D., Lee, S., Ou, J. H. and Jung, J. U. (2008) Beyond autophagy: the role of UVRAG in membrane trafficking. Autophagy 4, 817-820 PubMed
    • (2008) Autophagy , vol.4 , pp. 817-820
    • Liang, C.1    Sir, D.2    Lee, S.3    Ou, J.H.4    Jung, J.U.5
  • 30
    • 0242268528 scopus 로고    scopus 로고
    • Human VPS34 and p150 are Rab7 interacting partners
    • DOI 10.1034/j.1600-0854.2003.00133.x
    • Stein, M. P., Feng, Y., Cooper, K. L., Welford, A. M. and Wandinger-Ness, A. (2003) Human VPS34 and p150 are Rab7 interacting partners. Traffic 4, 754-771 CrossRef PubMed (Pubitemid 37361856)
    • (2003) Traffic , vol.4 , Issue.11 , pp. 754-771
    • Stein, M.-P.1    Feng, Y.2    Cooper, K.L.3    Welford, A.M.4    Wandinger-Ness, A.5
  • 31
    • 25444457577 scopus 로고    scopus 로고
    • hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase
    • DOI 10.1074/jbc.M507201200
    • Byfield, M. P., Murray, J. T. and Backer, J. M. (2005) hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase. J. Biol. Chem. 280, 33076-33082 CrossRef PubMed (Pubitemid 41368357)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.38 , pp. 33076-33082
    • Byfield, M.P.1    Murray, J.T.2    Backer, J.M.3
  • 32
    • 84890848742 scopus 로고    scopus 로고
    • Regulation of PIK3C3/VPS34 complexes by MTOR in nutrient stress-induced autophagy
    • CrossRef
    • Yuan, H. X., Russell, R. C. and Guan, K. L. (2013) Regulation of PIK3C3/VPS34 complexes by MTOR in nutrient stress-induced autophagy. Autophagy 9, CrossRef
    • (2013) Autophagy , vol.9
    • Yuan, H.X.1    Russell, R.C.2    Guan, K.L.3
  • 34
    • 84872586081 scopus 로고    scopus 로고
    • Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy
    • CrossRef PubMed
    • Kim, J., Kim, Y. C., Fang, C., Russell, R. C., Kim, J. H., Fan, W., Liu, R., Zhong, Q. and Guan, K. L. (2013) Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy. Cell 152, 290-303 CrossRef PubMed
    • (2013) Cell , vol.152 , pp. 290-303
    • Kim, J.1    Kim, Y.C.2    Fang, C.3    Russell, R.C.4    Kim, J.H.5    Fan, W.6    Liu, R.7    Zhong, Q.8    Guan, K.L.9
  • 35
    • 84887543464 scopus 로고    scopus 로고
    • Atg38 is required for autophagy-specific phosphatidylinositol 3-kinase complex integrity
    • CrossRef PubMed
    • Araki, Y., Ku, W. C., Akioka, M., May, A. I., Hayashi, Y., Arisaka, F., Ishihama, Y. and Ohsumi, Y. (2013) Atg38 is required for autophagy-specific phosphatidylinositol 3-kinase complex integrity. J. Cell Biol. 203, 299-313 CrossRef PubMed
    • (2013) J. Cell Biol. , vol.203 , pp. 299-313
    • Araki, Y.1    Ku, W.C.2    Akioka, M.3    May, A.I.4    Hayashi, Y.5    Arisaka, F.6    Ishihama, Y.7    Ohsumi, Y.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.