Inhibition of Histone Deacetylase 3 Restores amyloid-β Oligomer-Induced Plasticity Deficit in Hippocampal CA1 Pyramidal Neurons

Journal of Alzheimer's Disease

Volumn 51, Issue 3, 2016, Pages 783-791

  Krishna, Kumar ^a   Behnisch, Thomas ^b   Sajikumar, Sreedharan ^a,c  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b FUDAN UNIVERSITY   (China)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

amyloid oligomer; epigenetics; HDAC3; long term potentiation; RGFP966; synaptic plasticity

Indexed keywords

AMYLOID BETA PROTEIN; HISTONE DEACETYLASE 3; HISTONE DEACETYLASE INHIBITOR; OLIGOMER; RGFP 966; UNCLASSIFIED DRUG; ACRYLAMIDE DERIVATIVE; AMYLOID BETA-PROTEIN (1-42); HISTONE DEACETYLASE; PEPTIDE FRAGMENT; PHENYLENEDIAMINE DERIVATIVE; RGFP966;

ANIMAL TISSUE; ARTICLE; ATTENUATION; CONTROLLED STUDY; ELECTROPHYSIOLOGY; ENZYME INHIBITION; EXCITATORY POSTSYNAPTIC POTENTIAL; GLIA; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL SLICE; HISTONE ACETYLATION; LONG TERM POTENTIATION; MALE; MEMBRANE RESISTANCE; NERVE CELL PLASTICITY; NERVE EXCITABILITY; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; SYNAPTIC TRANSMISSION; VOLTAGE CLAMP TECHNIQUE; ALZHEIMER DISEASE; ANIMAL; DRUG EFFECTS; ENZYMOLOGY; HIPPOCAMPUS; METABOLISM; PATCH CLAMP TECHNIQUE; PHYSIOLOGY; TISSUE CULTURE TECHNIQUE; WISTAR RAT;

ACRYLAMIDES; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; EXCITATORY POSTSYNAPTIC POTENTIALS; HIPPOCAMPUS; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; LONG-TERM POTENTIATION; MALE; PATCH-CLAMP TECHNIQUES; PEPTIDE FRAGMENTS; PHENYLENEDIAMINES; PYRAMIDAL CELLS; RATS, WISTAR; TISSUE CULTURE TECHNIQUES;

EID: 84963750836     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-150838     Document Type: Article

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