Pharmacological Selectivity Within Class i Histone Deacetylases Predicts Effects on Synaptic Function and Memory Rescue

Neuropsychopharmacology

Volumn 40, Issue 10, 2015, Pages 2307-2316

  Rumbaugh, Gavin ^a   Sillivan, Stephanie E ^a   Ozkan, Emin D ^a   Rojas, Camilo S ^a   Hubbs, Christopher R ^a   Aceti, Massimiliano ^a   Kilgore, Mark ^b   Kudugunti, Shashi ^c   Puthanveettil, Sathyanarayanan V ^a   Sweatt, J David ^b   Rusche, James ^c   Miller, Courtney A ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b University of Alabama at Birmingham   (United States)

^c REPLIGEN CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE DEACETYLASE INHIBITOR; RGFP 233; RGFP 966; RGFP 968; SYNAPSIN I; SYNAPTOPHYSIN; UNCLASSIFIED DRUG; AMYLOID PRECURSOR PROTEIN; GREEN FLUORESCENT PROTEIN; HISTONE DEACETYLASE; HYDROXAMIC ACID; PRESENILIN 1; PSEN1 PROTEIN, HUMAN; TRICHOSTATIN A;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN ELECTROPHYSIOLOGY; COGNITION; CONTROLLED STUDY; DENDRITIC SPINE; DORSAL HIPPOCAMPUS; DRUG EFFICACY; ENZYME INHIBITION; FEAR; GENE EXPRESSION PROFILING; HIPPOCAMPAL CA1 REGION; MEMORY; MOUSE; NERVE CELL CULTURE; NONHUMAN; PREDICTION; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RNA SEQUENCE; SYNAPSE; SYNAPSE VESICLE; SYNAPTOGENESIS; SYNAPTOSOME; ALZHEIMER DISEASE; ANIMAL; C57BL MOUSE; CELL CULTURE; COMPLICATION; CONDITIONING; DISEASE MODEL; DRUG EFFECTS; GENETICS; HUMAN; MEMORY DISORDERS; METABOLISM; MUTATION; NERVE CELL; NEWBORN; PATHOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ANIMALS, NEWBORN; CELLS, CULTURED; CONDITIONING (PSYCHOLOGY); DISEASE MODELS, ANIMAL; FEAR; GENE EXPRESSION PROFILING; GREEN FLUORESCENT PROTEINS; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HUMANS; HYDROXAMIC ACIDS; MEMORY DISORDERS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; NEURONS; PRESENILIN-1; SYNAPSES; SYNAPTOPHYSIN;

EID: 84939251632     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2015.93     Document Type: Article

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