Mild endothelial dysfunction in Sirt3 knockout mice fed a high-cholesterol diet: protective role of a novel C/EBP-β-dependent feedback regulation of SOD2

Basic Research in Cardiology

Volumn 111, Issue 3, 2016, Pages

  Winnik, Stephan ^a,b   Gaul, Daniel S ^b   Siciliani, Giovanni ^b   Lohmann, Christine ^b   Pasterk, Lisa ^b,c   Calatayud, Natacha ^b   Weber, Julien ^b   Eriksson, Urs ^b,d   Auwerx, Johan ^e   van Tits, Lambertus J ^b   Lüscher, Thomas F ^a,b   Matter, Christian M ^a,b  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c MEDICAL UNIVERSITY OF GRAZ   (Austria)

^d GZO Regional Health Center Wetzikon   (Switzerland)

^e EPFL   (Switzerland)

Author keywords

C EBP ; Endothelial function; Oxidative stress; Sirt3; SOD2

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN BETA; ENDOTHELIAL NITRIC OXIDE SYNTHASE; MANGANESE SUPEROXIDE DISMUTASE; SIRTUIN 3; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROSCLEROSIS; BIOACCUMULATION; CELL DEATH; CHOLESTEROL DIET; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ELECTROSPINNING; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; FEEDBACK SYSTEM; FLUORESCENCE IMAGING; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MALE; MOUSE; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; WEIGHT GAIN; ANIMAL; C57BL MOUSE; CELL LINE; DEFICIENCY; DISEASE MODEL; ELECTRON SPIN RESONANCE; GENETIC TRANSFECTION; KNOCKOUT MOUSE; LIPID DIET; METABOLISM; PHYSIOLOGICAL FEEDBACK; PHYSIOLOGY; POLYMERASE CHAIN REACTION;

ANIMALS; CCAAT-ENHANCER-BINDING PROTEIN-BETA; CELL LINE; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; ELECTRON SPIN RESONANCE SPECTROSCOPY; ENDOTHELIAL CELLS; FEEDBACK, PHYSIOLOGICAL; HUMANS; IMMUNOPRECIPITATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; SIRTUIN 3; SUPEROXIDE DISMUTASE; TRANSFECTION;

EID: 84963738893     PISSN: 03008428     EISSN: 14351803     Source Type: Journal    
DOI: 10.1007/s00395-016-0552-7     Document Type: Article

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