SIRT3 deficiency impairs mitochondrial and contractile function in the heart

Basic Research in Cardiology

Volumn 110, Issue 4, 2015, Pages 1-20

  Koentges, Christoph ^a   Pfeil, Katharina ^a   Schnick, Tilman ^a   Wiese, Sebastian ^a   Dahlbock, Rabea ^a   Cimolai, Maria C ^a   Meyer Steenbuck, Maximilian ^a   Cenkerova, Katarina ^a   Hoffmann, Michael M ^a,b   Jaeger, Carsten ^a   Odening, Katja E ^a   Kammerer, Bernd ^a   Hein, Lutz ^a   Bode, Christoph ^a   Bugger, Heiko ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Cardiac function; Energetics; Mitochondria; Sirtuin 3

Indexed keywords

ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; MITOCHONDRIAL PROTEIN; PALMITIC ACID; SIRTUIN 3; TRICARBOXYLIC ACID; SIRT3 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA CONSTRICTION; ARTICLE; BREATHING; CITRIC ACID CYCLE; CONTROLLED STUDY; DEPLETION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ECHOCARDIOGRAPHY; ENERGY TRANSFER; ENZYME ACTIVITY; ENZYME DEFICIENCY; FATTY ACID OXIDATION; FATTY ACID TRANSPORT; GLYCOLYSIS; HEART CONTRACTION; HEART DISEASE; HEART EJECTION FRACTION; HEART HYPERTROPHY; HEART MITOCHONDRION; HEART MUSCLE FIBROSIS; HEART MUSCLE METABOLISM; HEART MUSCLE OXYGEN CONSUMPTION; HEART VOLUME; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOLATED HEART; LIQUID CHROMATOGRAPHY; MALE; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PROTEIN ACETYLATION; RESPIRATORY CHAIN; TANDEM MASS SPECTROMETRY; WILD TYPE MOUSE; ANIMAL; ENERGY METABOLISM; KNOCKOUT MOUSE; OXIDATIVE PHOSPHORYLATION; PHYSIOLOGY;

ANIMALS; CITRIC ACID CYCLE; ENERGY METABOLISM; MALE; MICE; MICE, KNOCKOUT; MITOCHONDRIA, HEART; MYOCARDIAL CONTRACTION; OXIDATIVE PHOSPHORYLATION; SIRTUIN 3;

EID: 84929088095     PISSN: 03008428     EISSN: 14351803     Source Type: Journal    
DOI: 10.1007/s00395-015-0493-6     Document Type: Article

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