IRAK-M Expression in Tumor Cells Supports Colorectal Cancer Progression through Reduction of Antimicrobial Defense and Stabilization of STAT3

Cancer Cell

Volumn 29, Issue 5, 2016, Pages 684-696

  Kesselring, Rebecca ^a   Glaesner, Joachim ^a   Hiergeist, Andreas ^a   Naschberger, Elisabeth ^b   Neumann, Helmut ^b   Brunner, Stefan M ^a   Wege, Anja K ^c   Seebauer, Caroline ^a   Köhl, Gudrun ^a   Merkl, Susanne ^b   Croner, Roland S ^b   Hackl, Christina ^a   Stürzl, Michael ^b   Neurath, Markus F ^b   Gessner, André ^a   Schlitt, Hans Juergen ^a   Geissler, Edward K ^a   Fichtner Feigl, Stefan ^a  

^a UNIVERSITY HOSPITAL REGENSBURG   (Germany)

^b UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^c UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

Colorectal cancer; IRAK M; Microbiome; STAT3; Toll like receptors; Wnt signaling

Indexed keywords

INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 3; STAT3 PROTEIN; WNT PROTEIN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; IRAK3 PROTEIN, HUMAN; IRAK3 PROTEIN, MOUSE; TOLL LIKE RECEPTOR;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL COLONIZATION; CANCER GROWTH; CANCER PROGNOSIS; CANCER SURVIVAL; CARCINOGENESIS; CELL PROLIFERATION; COLORECTAL CANCER; EPITHELIUM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STABILITY; TUMOR CELL; TUMOR MICROENVIRONMENT; ANIMAL; C57BL MOUSE; COLITIS; COLORECTAL TUMOR; DISEASE COURSE; GENETICS; HOST PATHOGEN INTERACTION; HUMAN; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; MICROBIOLOGY; MICROFLORA; NUDE MOUSE; PHOSPHORYLATION; PROGNOSIS; SURVIVAL ANALYSIS; WNT SIGNALING PATHWAY;

ANIMALS; CELL PROLIFERATION; COLITIS; COLORECTAL NEOPLASMS; DISEASE PROGRESSION; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, NUDE; MICROBIOTA; PHOSPHORYLATION; PROGNOSIS; PROTEIN STABILITY; STAT3 TRANSCRIPTION FACTOR; SURVIVAL ANALYSIS; TOLL-LIKE RECEPTORS; WNT SIGNALING PATHWAY;

EID: 84963571348     PISSN: 15356108     EISSN: 18783686     Source Type: Journal    
DOI: 10.1016/j.ccell.2016.03.014     Document Type: Article

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