-
1
-
-
46949091517
-
Refinement and standardization of synthetic biological parts and devices
-
Canton, B., Labno, A., Endy, D. Refinement and standardization of synthetic biological parts and devices. Nat. Biotechnol. 26, 787-793 (2008).
-
(2008)
Nat. Biotechnol.
, vol.26
, pp. 787-793
-
-
Canton, B.1
Labno, A.2
Endy, D.3
-
2
-
-
78649716727
-
Manufacturing molecules through metabolic engineering
-
Keasling, J. D. Manufacturing molecules through metabolic engineering. Science 330, 1355-1358 (2010).
-
(2010)
Science
, vol.330
, pp. 1355-1358
-
-
Keasling, J.D.1
-
3
-
-
84860803588
-
Refactoring the nitrogen fixation gene cluster from Klebsiella oxytoca
-
Temme, K., Zhao, D. H., Voigt, C. A. Refactoring the nitrogen fixation gene cluster from Klebsiella oxytoca. Proc. Natl Acad. Sci. USA 109, 7085-7090 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 7085-7090
-
-
Temme, K.1
Zhao, D.H.2
Voigt, C.A.3
-
4
-
-
0037168510
-
Directed evolution of a genetic circuit
-
Yokobayashi, Y., Weiss, R., Arnold, F. H. Directed evolution of a genetic circuit. Proc. Natl Acad. Sci. USA 99, 16587-16591 (2002).
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 16587-16591
-
-
Yokobayashi, Y.1
Weiss, R.2
Arnold, F.H.3
-
5
-
-
70450242805
-
Exploring protein fitness landscapes by directed evolution
-
Romero, P. A., Arnold, F. H. Exploring protein fitness landscapes by directed evolution. Nat. Rev. Mol. Cell Biol. 10, 866-876 (2009).
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 866-876
-
-
Romero, P.A.1
Arnold, F.H.2
-
6
-
-
84865278051
-
Customized optimization of metabolic pathways by combinatorial transcriptional engineering
-
Du, J., Yuan, Y. B., Si, T., Lian, J. Z., Zhao, H. M. Customized optimization of metabolic pathways by combinatorial transcriptional engineering. Nucleic Acids Res. 40, e142 (2012).
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. e142
-
-
Du, J.1
Yuan, Y.B.2
Si, T.3
Lian, J.Z.4
Zhao, H.M.5
-
7
-
-
84894319806
-
Metabolic pathway optimization using ribosome binding site variants and combinatorial gene assembly
-
Nowroozi, F. F. et al. Metabolic pathway optimization using ribosome binding site variants and combinatorial gene assembly. Appl. Microbiol. Biotechnol. 98, 1567-1581 (2014).
-
(2014)
Appl. Microbiol. Biotechnol.
, vol.98
, pp. 1567-1581
-
-
Nowroozi, F.F.1
-
8
-
-
84921517479
-
Functional optimization of gene clusters by combinatorial design and assembly
-
Smanski, M. J. et al. Functional optimization of gene clusters by combinatorial design and assembly. Nat. Biotechnol. 32, 1241-1249 (2014).
-
(2014)
Nat. Biotechnol.
, vol.32
, pp. 1241-1249
-
-
Smanski, M.J.1
-
9
-
-
84903748219
-
Employing a combinatorial expression approach to characterize xylose utilization in Saccharomyces cerevisiae
-
Latimer, L. N. et al. Employing a combinatorial expression approach to characterize xylose utilization in Saccharomyces cerevisiae. Metab. Eng. 25, 20-29 (2014).
-
(2014)
Metab. Eng.
, vol.25
, pp. 20-29
-
-
Latimer, L.N.1
-
10
-
-
33847309176
-
Balancing a heterologous mevalonate pathway for improved isoprenoid production in Escherichia coli
-
Pitera, D. J., Paddon, C. J., Newman, J. D., Keasling, J. D. Balancing a heterologous mevalonate pathway for improved isoprenoid production in Escherichia coli. Metab. Eng. 9, 193-207 (2007).
-
(2007)
Metab. Eng.
, vol.9
, pp. 193-207
-
-
Pitera, D.J.1
Paddon, C.J.2
Newman, J.D.3
Keasling, J.D.4
-
11
-
-
79960569987
-
Rapid optimization of gene dosage in e
-
Kittleson, J. T., Cheung, S., Anderson, J. C. Rapid optimization of gene dosage in E. coli using DIAL strains. J. Biol. Eng. 5, 10 (2011).
-
(2011)
Coli Using DIAL Strains. J. Biol. Eng.
, vol.5
, pp. 10
-
-
Kittleson, J.T.1
Cheung, S.2
Anderson, J.C.3
-
12
-
-
24644515752
-
Tuning genetic control through promoter engineering
-
Alper, H., Fischer, C., Nevoigt, E., Stephanopoulos, G. Tuning genetic control through promoter engineering. Proc. Natl Acad. Sci. USA 102, 12678-12683 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 12678-12683
-
-
Alper, H.1
Fischer, C.2
Nevoigt, E.3
Stephanopoulos, G.4
-
13
-
-
36249017917
-
Programming gene expression with combinatorial promoters
-
Cox, R. S., Surette, M. G., Elowitz, M. B. Programming gene expression with combinatorial promoters. Mol. Syst. Biol. 3, 145 (2007).
-
(2007)
Mol. Syst. Biol.
, vol.3
, pp. 145
-
-
Cox, R.S.1
Surette, M.G.2
Elowitz, M.B.3
-
14
-
-
66149172363
-
Diversity-based model-guided construction of synthetic gene networks with predicted functions
-
Ellis, T.,Wang, X., Collins, J. J. Diversity-based, model-guided construction of synthetic gene networks with predicted functions. Nat. Biotechnol. 27, 465-471 (2009).
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 465-471
-
-
Ellis, T.1
Wang, X.2
Collins, J.J.3
-
15
-
-
70349199628
-
Design parameters to control synthetic gene expression in Escherichia coli
-
Welch, M. et al. Design parameters to control synthetic gene expression in Escherichia coli. PLoS ONE 4, e7002 (2009).
-
(2009)
PLoS ONE
, vol.4
, pp. e7002
-
-
Welch, M.1
-
16
-
-
67650687073
-
You're one in a googol: Optimizing genes for protein expression
-
Welch, M., Villalobos, A., Gustafsson, C., Minshull, J. You're one in a googol: optimizing genes for protein expression. J. R. Soc. Interface 6, S467-S476 (2009).
-
(2009)
J. R. Soc. Interface
, vol.6
, pp. S467-S476
-
-
Welch, M.1
Villalobos, A.2
Gustafsson, C.3
Minshull, J.4
-
17
-
-
34547607675
-
A synthetic gene network for tuning protein degradation in Saccharomyces cerevisiae
-
Grilly, C., Stricker, J., Pang, W. L., Bennett, M. R., Hasty, J. A synthetic gene network for tuning protein degradation in Saccharomyces cerevisiae. Mol. Syst. Biol. 3, 127 (2007).
-
(2007)
Mol. Syst. Biol.
, vol.3
, pp. 127
-
-
Grilly, C.1
Stricker, J.2
Pang, W.L.3
Bennett, M.R.4
Hasty, J.5
-
18
-
-
84877292750
-
Spanning high-dimensional expression space using ribosome-binding site combinatorics
-
Zelcbuch, L. et al. Spanning high-dimensional expression space using ribosome-binding site combinatorics. Nucleic Acids Res. 41, e98 (2013).
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. e98
-
-
Zelcbuch, L.1
-
19
-
-
84875720517
-
Precise and reliable gene expression via standard transcription and translation initiation elements
-
Mutalik, V. K. et al. Precise and reliable gene expression via standard transcription and translation initiation elements. Nat. Methods 10, 354-360 (2013).
-
(2013)
Nat. Methods
, vol.10
, pp. 354-360
-
-
Mutalik, V.K.1
-
20
-
-
70349964350
-
Automated design of synthetic ribosome binding sites to control protein expression
-
Salis, H. M., Mirsky, E. A., Voigt, C. A. Automated design of synthetic ribosome binding sites to control protein expression. Nat. Biotechnol. 27, 946-950 (2009).
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 946-950
-
-
Salis, H.M.1
Mirsky, E.A.2
Voigt, C.A.3
-
21
-
-
84903766210
-
Efficient search, mapping, and optimization of multi-protein genetic systems in diverse bacteria
-
Farasat, I. et al. Efficient search, mapping, and optimization of multi-protein genetic systems in diverse bacteria. Mol. Syst. Biol. 10, 731 (2014).
-
(2014)
Mol. Syst. Biol.
, vol.10
, pp. 731
-
-
Farasat, I.1
-
22
-
-
14844340954
-
Initiation of protein synthesis in bacteria
-
Laursen, B. S., Sorensen, H. P., Mortensen, K. K., Sperling-Petersen, H. U. Initiation of protein synthesis in bacteria. Microbiol. Mol. Biol. Rev. 69, 101-123 (2005)
-
(2005)
Microbiol. Mol. Biol. Rev.
, vol.69
, pp. 101-123
-
-
Laursen, B.S.1
Sorensen, H.P.2
Mortensen, K.K.3
Sperling-Petersen, H.U.4
-
23
-
-
64849114915
-
Coding-sequence determinants of gene expression in Escherichia coli
-
Kudla, G., Murray, A. W., Tollervey, D., Plotkin, J. B. Coding-sequence determinants of gene expression in Escherichia coli. Science 324, 255-258 (2009).
-
(2009)
Science
, vol.324
, pp. 255-258
-
-
Kudla, G.1
Murray, A.W.2
Tollervey, D.3
Plotkin, J.B.4
-
24
-
-
77957797837
-
RBSDesigner: Software for designing synthetic ribosome binding sites that yields a desired level of protein expression
-
Na, D., Lee, D. RBSDesigner: software for designing synthetic ribosome binding sites that yields a desired level of protein expression. Bioinformatics 26, 2633-2634 (2010).
-
(2010)
Bioinformatics
, vol.26
, pp. 2633-2634
-
-
Na, D.1
Lee, D.2
-
25
-
-
84870851210
-
Predictive design of mRNA translation initiation region to control prokaryotic translation efficiency
-
Seo, S. W. et al. Predictive design of mRNA translation initiation region to control prokaryotic translation efficiency. Metab. Eng. 15, 67-74 (2013).
-
(2013)
Metab. Eng.
, vol.15
, pp. 67-74
-
-
Seo, S.W.1
-
26
-
-
84895827954
-
Translation rate is controlled by coupled trade-offs between site accessibility, selective RNA unfolding and sliding at upstream standby sites
-
Borujeni, A. E., Channarasappa, A. S., Salis, H. M. Translation rate is controlled by coupled trade-offs between site accessibility, selective RNA unfolding and sliding at upstream standby sites. Nucleic Acids Res. 42, 2646-2659 (2014).
-
(2014)
Nucleic Acids Res.
, vol.42
, pp. 2646-2659
-
-
Borujeni, A.E.1
Channarasappa, A.S.2
Salis, H.M.3
-
27
-
-
84911480225
-
Predicting translation initiation rates for designing synthetic biology
-
Reeve, B., Hargest, T., Gilbert, C., Ellis, T. Predicting translation initiation rates for designing synthetic biology. Front. Bioeng. Biotechnol. 2, 1 (2014).
-
(2014)
Front. Bioeng. Biotechnol.
, vol.2
, pp. 1
-
-
Reeve, B.1
Hargest, T.2
Gilbert, C.3
Ellis, T.4
-
28
-
-
84861905596
-
Potential applications of violacein: A microbial pigment
-
Duran, M. et al. Potential applications of violacein: a microbial pigment. Med. Chem. Res. 21, 1524-1532 (2012).
-
(2012)
Med. Chem. Res.
, vol.21
, pp. 1524-1532
-
-
Duran, M.1
-
29
-
-
37349049987
-
Violacein: Properties and biological activities
-
Duran, N. et al. Violacein: properties and biological activities. Biotechnol. Appl. Biochem. 48, 127-133 (2007).
-
(2007)
Biotechnol. Appl. Biochem.
, vol.48
, pp. 127-133
-
-
Duran, N.1
-
30
-
-
4444302229
-
Molecular mechanism of violacein-mediated human leukemia cell death
-
Ferreira, C. V. et al. Molecular mechanism of violacein-mediated human leukemia cell death. Blood 104, 1459-1464 (2004).
-
(2004)
Blood
, vol.104
, pp. 1459-1464
-
-
Ferreira, C.V.1
-
31
-
-
54349090614
-
Addressing the numbers problem in directed evolution
-
Reetz, M. T., Kahakeaw, D., Lohmer, R. Addressing the numbers problem in directed evolution. Chembiochem. 9, 1797-1804 (2008).
-
(2008)
Chembiochem.
, vol.9
, pp. 1797-1804
-
-
Reetz, M.T.1
Kahakeaw, D.2
Lohmer, R.3
-
32
-
-
0035195767
-
Factorial design and response surface optimization of crude violacein for Chromobacterium violaceum production
-
Mendes, A. S., de Carvalho, J. E., Duarte, M. C. T., Duran, N., Bruns, R. E. Factorial design and response surface optimization of crude violacein for Chromobacterium violaceum production. Biotechnol. Lett. 23, 1963-1969 (2001).
-
(2001)
Biotechnol. Lett.
, vol.23
, pp. 1963-1969
-
-
Mendes, A.S.1
De Carvalho, J.E.2
Duarte, M.C.T.3
Duran, N.4
Bruns, R.E.5
-
33
-
-
33845934004
-
In vitro biosynthesis of violacein from L-tryptophan by the enzymes VioA-E from Chromobacterium violaceum
-
Balibar, C. J., Walsh, C. T. In vitro biosynthesis of violacein from L-tryptophan by the enzymes VioA-E from Chromobacterium violaceum. Biochemistry 45, 15444-15457 (2006).
-
(2006)
Biochemistry
, vol.45
, pp. 15444-15457
-
-
Balibar, C.J.1
Walsh, C.T.2
-
34
-
-
33747160432
-
Reevaluation of the violacein biosynthetic pathway and its relationship to indolocarbazole biosynthesis
-
Sanchez, C., Brana, A. F., Mendez, C., Salas, J. A. Reevaluation of the violacein biosynthetic pathway and its relationship to indolocarbazole biosynthesis. Chembiochem. 7, 1231-1240 (2006).
-
(2006)
Chembiochem.
, vol.7
, pp. 1231-1240
-
-
Sanchez, C.1
Brana, A.F.2
Mendez, C.3
Salas, J.A.4
-
35
-
-
84858009322
-
Microbial production of the drugs violacein and deoxyviolacein: Analytical development and strain comparison
-
Rodrigues, A. L. et al. Microbial production of the drugs violacein and deoxyviolacein: analytical development and strain comparison. Biotechnol. Lett. 34, 717-720 (2012).
-
(2012)
Biotechnol. Lett.
, vol.34
, pp. 717-720
-
-
Rodrigues, A.L.1
-
36
-
-
84884166429
-
Systems metabolic engineering of Escherichia coli for production of the antitumor drugs violacein and deoxyviolacein
-
Rodrigues, A. L. et al. Systems metabolic engineering of Escherichia coli for production of the antitumor drugs violacein and deoxyviolacein. Metab. Eng. 20, 29-41 (2013).
-
(2013)
Metab. Eng.
, vol.20
, pp. 29-41
-
-
Rodrigues, A.L.1
-
37
-
-
84924140841
-
High crude violacein production from glucose by Escherichia coli engineered with interactive control of tryptophan pathway and violacein biosynthetic pathway
-
Fang, M. Y. et al. High crude violacein production from glucose by Escherichia coli engineered with interactive control of tryptophan pathway and violacein biosynthetic pathway. Microb. Cell Fact. 14, 8 (2015).
-
(2015)
Microb. Cell Fact.
, vol.14
, pp. 8
-
-
Fang, M.Y.1
-
38
-
-
84890395226
-
Expression-level optimization of a multi-enzyme pathway in the absence of a high-throughput assay
-
Lee, M. E., Aswani, A., Han, A. S., Tomlin, C. J., Dueber, J. E. Expression-level optimization of a multi-enzyme pathway in the absence of a high-throughput assay. Nucleic Acids Res. 41, 10668-10678 (2013).
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. 10668-10678
-
-
Lee, M.E.1
Aswani, A.2
Han, A.S.3
Tomlin, C.J.4
Dueber, J.E.5
-
39
-
-
84871594181
-
Scalable plasmid transfer using engineered P1-based phagemids
-
Kittleson, J. T., DeLoache, W., Cheng, H. Y., Anderson, J. C. Scalable plasmid transfer using engineered P1-based phagemids. ACS Syn. Biol. 1, 583-589 (2012).
-
(2012)
ACS Syn. Biol.
, vol.1
, pp. 583-589
-
-
Kittleson, J.T.1
DeLoache, W.2
Cheng, H.Y.3
Anderson, J.C.4
-
40
-
-
84941871856
-
The Kolmogorov-Smirnov test for goodness of fit
-
Massey, F. J. The Kolmogorov-Smirnov test for goodness of fit. J. Am. Stat. Assoc. 46, 68-78 (1951).
-
(1951)
J. Am. Stat. Assoc.
, vol.46
, pp. 68-78
-
-
Massey, F.J.1
-
42
-
-
0032032711
-
Green fluorescent protein as a real time quantitative reporter of heterologous protein production
-
Albano, C. R., Randers-Eichhorn, L., Bentley, W. E., Rao, G. Green fluorescent protein as a real time quantitative reporter of heterologous protein production. Biotechnol. Prog. 14, 351-354 (1998).
-
(1998)
Biotechnol. Prog.
, vol.14
, pp. 351-354
-
-
Albano, C.R.1
Randers-Eichhorn, L.2
Bentley, W.E.3
Rao, G.4
-
44
-
-
0033050514
-
An alkane-responsive expression system for the production of fine chemicals
-
Panke, S., Meyer, A., Huber, C. M., Witholt, B., Wubbolts, M. G. An alkane-responsive expression system for the production of fine chemicals. Appl. Environ. Microbiol. 65, 2324-2332 (1999).
-
(1999)
Appl. Environ. Microbiol.
, vol.65
, pp. 2324-2332
-
-
Panke, S.1
Meyer, A.2
Huber, C.M.3
Witholt, B.4
Wubbolts, M.G.5
-
45
-
-
14844294424
-
Protein production by auto-induction in high-density shaking cultures
-
Studier, F. W. Protein production by auto-induction in high-density shaking cultures. Protein Expr. Purif. 41, 207-234 (2005).
-
(2005)
Protein Expr. Purif.
, vol.41
, pp. 207-234
-
-
Studier, F.W.1
-
46
-
-
84876567509
-
The Standard European Vector Architecture (SEVA): A coherent platform for the analysis and deployment of complex prokaryotic phenotypes
-
Silva-Rocha, R. et al. The Standard European Vector Architecture (SEVA): a coherent platform for the analysis and deployment of complex prokaryotic phenotypes. Nucleic Acids Res. 41, D666-D675 (2013).
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. D666-D675
-
-
Silva-Rocha, R.1
-
47
-
-
0021943518
-
Improved M13 phage cloning vectors and host strains-nucleotide-sequences of the M13mp18 and pUC19 vectors
-
Yanischperron, C., Vieira, J., Messing, J. Improved M13 phage cloning vectors and host strains-nucleotide-sequences of the M13mp18 and pUC19 vectors. Gene 33, 103-119 (1985).
-
(1985)
Gene
, vol.33
, pp. 103-119
-
-
Yanischperron, C.1
Vieira, J.2
Messing, J.3
-
48
-
-
0023464708
-
Vectors for selective expression of cloned DNAs by T7 RNA-polymerase
-
Rosenberg, A. H. et al. Vectors for selective expression of cloned DNAs by T7 RNA-polymerase. Gene 56, 125-135 (1987).
-
(1987)
Gene
, vol.56
, pp. 125-135
-
-
Rosenberg, A.H.1
-
49
-
-
34248559599
-
Gene splicing and mutagenesis by PCR-driven overlap extension
-
Heckman, K. L., Pease, L. R. Gene splicing and mutagenesis by PCR-driven overlap extension. Nat. Protoc. 2, 924-932 (2007).
-
(2007)
Nat. Protoc.
, vol.2
, pp. 924-932
-
-
Heckman, K.L.1
Pease, L.R.2
-
50
-
-
0029063837
-
Activation of the transcriptional regulator XylR of Pseudomonas putida by release of repression between functional domains
-
Fernandez, S., Delorenzo, V., Perezmartin, J. Activation of the transcriptional regulator XylR of Pseudomonas putida by release of repression between functional domains. Mol. Microbiol. 16, 205-213 (1995).
-
(1995)
Mol. Microbiol.
, vol.16
, pp. 205-213
-
-
Fernandez, S.1
Delorenzo, V.2
Perezmartin, J.3
|