Microbial production of the drugs violacein and deoxyviolacein: Analytical development and strain comparison

Biotechnology Letters

Volumn 34, Issue 4, 2012, Pages 717-720

  Rodrigues, A L ^a   Göcke, Yvonne ^a   Bolten, Christoph ^a   Brock, Nelson L ^a   Dickschat, Jeroen S ^a   Wittmann, Christoph ^a  

^a TECHNICAL UNIVERSITY OF BRAUNSCHWEIG   (Germany)

Author keywords

Deoxyviolacein; Escherichia coli; Janthinobacterium lividum; Violacein

Indexed keywords

ANALYTICAL METHOD; BIOLOGICAL PROPERTIES; DEOXYVIOLACEIN; HPLC METHOD; JANTHINOBACTERIUM LIVIDUM; MICROBIAL CULTURE; MICROBIAL PRODUCTION; RECOMBINANT ESCHERICHIA COLI; VIOLACEIN;

BIOTECHNOLOGY;

ESCHERICHIA COLI;

BIOLOGICAL PRODUCT; INDOLE DERIVATIVE; VIOLACEIN;

ARTICLE; CHEMICAL ANALYSIS; COMPARATIVE STUDY; ESCHERICHIA COLI; GROWTH, DEVELOPMENT AND AGING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOLATION AND PURIFICATION; METABOLISM; METHODOLOGY; OXALOBACTERACEAE;

BIOLOGICAL AGENTS; CHEMISTRY TECHNIQUES, ANALYTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ESCHERICHIA COLI; INDOLES; OXALOBACTERACEAE;

ESCHERICHIA COLI; JANTHINOBACTERIUM LIVIDUM;

EID: 84858009322     PISSN: 01415492     EISSN: 15736776     Source Type: Journal    
DOI: 10.1007/s10529-011-0827-x     Document Type: Article

References (11)

1. Andrighetti-Fröhner CR, Antonio RV, Creczynski-Pasa TB, Barardi CRM, Simões CMO (2003) Cytotoxicity and potential antiviral evaluation of violacein produced by Chromobacterium violaceum. Mem Inst Oswaldo Cruz 98: 843-848.
2. Bromberg N, Dreyfuss JL, Regatieri CV, Palladino MV, Duran N, Nader HB, Haun M, Justo GZ (2010) Growth inhibition and pro-apoptotic activity of violacein in Ehrlich ascites tumor. Chem Biol Interact 186(1): 43-52.
3. Jiang P, Wang H, Zhang C, Lou K, Xing XH (2009) Reconstruction of the violacein biosynthetic pathway from Duganella sp. B2 in different heterologous hosts. Appl Microbiol Biotechnol 86(4): 1077-1088.
4. May G, Brummer B, Ott H (1991) Treatment of prophylaxis of polio and herpes virus infections-comprises admin. of 3-(1, 2-dihydro-5-(5-hydroxy-1H- indol-3-yl)-2-oxo-3Hpyrrole-3-ylidene)-1, 3-dihydro-2H-indol-2-one. DE 3935066 Patent.
5. Mendes AS, de Carvalho JE, Duarte MCT, Duran N, Bruns RE (2001) Factorial design and response surface optimization of crude violacein for Chromobacterium violaceum production. Biotechnol Lett 23(23): 1963-1969.
6. Pantanella F, Berlutti F, Passariello C, Sarli S, Morea C, Schippa S (2007) Violacein and biofilm production in Janthinobacterium lividum. J Appl Microbiol 102(4): 992-999.
7. Rettori D, Durán N (1998) Production, extraction and purification of violacein: an antibiotic pigment produced by Chromobacterium violaceum. World J Microbiol Biotechnol 14(5): 685-688.
8. Rodrigues AL (2007) Heterologous production of violacein in Escherichia coli. Master Dissertation, Federal University of Santa Catarina, Florianópolis.
9. Sarovich DS, Pemberton JM (2007) pPSX: a novel vector for the cloning and heterologous expression of antitumor antibiotic gene clusters. Plasmid 57(3): 306-313.
10. Wang H, Jiang P, Lu Y, Ruan Z, Jiang R, Xing XH, Lou K, Wei D (2009) Optimization of culture conditions for violacein production by a new strain of Duganella sp. B2. Biochem Eng J 44(2-3): 119-124.
11. Wille G, Steglich W (2001) A short synthesis of the bacterial pigments violacein and deoxyviolacein. Synthesis 5: 759-762.