Factorial design and response surface optimization of crude violacein for Chromobacterium violaceum production

Biotechnology Letters

Volumn 23, Issue 23, 2001, Pages 1963-1969

  Mendes, Armando S ^a   De Carvalho, João E ^a,b   Duarte, Marta C T ^b   Durán, Nelson ^c,f   Bruns, Roy E ^d,e  

^a Faculdade de Cîencias Médicas

^b Unicamp   (Brazil)

^c Biological Chemistry Laboratory   (Brazil)

^d UNIVERSITY OF CAMPINAS   (Brazil)

^e Universidade de Mogi das Cruzes ^*  (Brazil)

^f UNIVERSIDADE DE MOGI DAS CRUZES   (Brazil)

Author keywords

Chromobacterium violaceum; Experimental design; Fermentation broth; Medium optimization; Violacein

Indexed keywords

ANTIINFECTIVE AGENT; UNCLASSIFIED DRUG; VIOLACEIN;

ARTICLE; BACTERIAL GROWTH; BIOMASS; CHROMOBACTERIUM; CHROMOBACTERIUM VIOLACEUM; CONTROLLED STUDY; CULTURE MEDIUM; DRUG SYNTHESIS; EXPERIMENTAL MODEL; FACTORIAL ANALYSIS; NONHUMAN; VALIDATION PROCESS;

BACTERIA (MICROORGANISMS); CHROMOBACTERIUM; CHROMOBACTERIUM VIOLACEUM;

EID: 0035195767     PISSN: 01415492     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1013734315525     Document Type: Article

References (17)

1. Biological activities of violacein, a new antitumoral indole derivative, in an inclusion complex with beta-cyclodextrin
2. Physiological aspects of violacein biosynthesis in nonproliferating cells
3. Nutritional requirements of Chromobacterium violaceum
4. Effect of primary metabolites on secondary metabolism
5. Biosyntesis of a trypanocide by Chromobacterium violaceum
6. Optimisation of medium composition for clavulanic acid production by Streptomyces clavuligerus
7. Conversion from tryptophan into violacein pigments by a cell-free system from Chromobacterium violaceum
8. Effect of cultural conditions on synthesis of violacein in mesophilic and psychrophilic strains of Chromobacterium
9. Violacein, an antibiotic pigment produced by Chromobacterium violaceum
10. Violacein cytotoxicity and induction of apoptosis in V79 cells
11. Effect of growth conditions on production of violacein by Chromobacterium violaceum (BB-78 strain)
12. Intact incorporation of the tryptophan molecule on the oxindole side, with intramolecular rearrangement of the indole ring on the 5-hydroxindole side
13. Atividade da violaceína in vitro sobre Mycobacterium tuberculosis H37RA
14. Defining an optimal carbon source/methionine feed strategy for growth and cephalosporin C formation by Cephalosporium acremonium