-
1
-
-
84872168596
-
Microglia: scapegoat, saboteur, or something else?
-
Aguzzi A., Barres B.A., Bennett M.L. Microglia: scapegoat, saboteur, or something else?. Science 2013, 339:156-161.
-
(2013)
Science
, vol.339
, pp. 156-161
-
-
Aguzzi, A.1
Barres, B.A.2
Bennett, M.L.3
-
2
-
-
84885821412
-
TREM2 and neurodegenerative disease
-
Benitez B.A., Cruchaga C. TREM2 and neurodegenerative disease. N. Engl. J. Med. 2013, 369:1567-1568.
-
(2013)
N. Engl. J. Med.
, vol.369
, pp. 1567-1568
-
-
Benitez, B.A.1
Cruchaga, C.2
-
3
-
-
84903366979
-
Missense variant in TREML2 protects against Alzheimer's disease
-
Benitez B.A., Jin S.C., Guerreiro R., Graham R., Lord J., Harold D., Sims R., Lambert J.C., Gibbs J.R., Bras J., Sassi C., Harari O., Bertelsen S., Lupton M.K., Powell J., Bellenguez C., Brown K., Medway C., Haddick P.C., van der Brug M.P., Bhangale T., Ortmann W., Behrens T., Mayeux R., Pericak-Vance M.A., Farrer L.A., Schellenberg G.D., Haines J.L., Turton J., Braae A., Barber I., Fagan A.M., Holtzman D.M., Morris J.C., Williams J., Kauwe J.S., Amouyel P., Morgan K., Singleton A., Hardy J., Goate A.M., Cruchaga C. Missense variant in TREML2 protects against Alzheimer's disease. Neurobiol. Aging 2014, 35:1510.e19-1510.e26.
-
(2014)
Neurobiol. Aging
, vol.35
, pp. 1510.e19-1510.e26
-
-
Benitez, B.A.1
Jin, S.C.2
Guerreiro, R.3
Graham, R.4
Lord, J.5
Harold, D.6
Sims, R.7
Lambert, J.C.8
Gibbs, J.R.9
Bras, J.10
Sassi, C.11
Harari, O.12
Bertelsen, S.13
Lupton, M.K.14
Powell, J.15
Bellenguez, C.16
Brown, K.17
Medway, C.18
Haddick, P.C.19
van der Brug, M.P.20
Bhangale, T.21
Ortmann, W.22
Behrens, T.23
Mayeux, R.24
Pericak-Vance, M.A.25
Farrer, L.A.26
Schellenberg, G.D.27
Haines, J.L.28
Turton, J.29
Braae, A.30
Barber, I.31
Fagan, A.M.32
Holtzman, D.M.33
Morris, J.C.34
Williams, J.35
Kauwe, J.S.36
Amouyel, P.37
Morgan, K.38
Singleton, A.39
Hardy, J.40
Goate, A.M.41
Cruchaga, C.42
more..
-
4
-
-
33845768784
-
Microglia-mediated neurotoxicity: uncovering the molecular mechanisms
-
Block M.L., Zecca L., Hong J.S. Microglia-mediated neurotoxicity: uncovering the molecular mechanisms. Nat. Rev. Neurosci. 2007, 8:57-69.
-
(2007)
Nat. Rev. Neurosci.
, vol.8
, pp. 57-69
-
-
Block, M.L.1
Zecca, L.2
Hong, J.S.3
-
5
-
-
0037805700
-
TREMs in the immune system and beyond
-
Colonna M. TREMs in the immune system and beyond. Nat. Rev. Immunol. 2003, 3:445-453.
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 445-453
-
-
Colonna, M.1
-
6
-
-
64049095240
-
TREM and TREM-like receptors in inflammation and disease
-
Ford J.W., McVicar D.W. TREM and TREM-like receptors in inflammation and disease. Curr. Opin. Immunol. 2009, 21:38-46.
-
(2009)
Curr. Opin. Immunol.
, vol.21
, pp. 38-46
-
-
Ford, J.W.1
McVicar, D.W.2
-
7
-
-
0031974406
-
Microglial response to amyloid plaques in APPsw transgenic mice
-
Frautschy S.A., Yang F., Irrizarry M., Hyman B., Saido T.C., Hsiao K., Cole G.M. Microglial response to amyloid plaques in APPsw transgenic mice. Am. J. Pathol. 1998, 152:307-317.
-
(1998)
Am. J. Pathol.
, vol.152
, pp. 307-317
-
-
Frautschy, S.A.1
Yang, F.2
Irrizarry, M.3
Hyman, B.4
Saido, T.C.5
Hsiao, K.6
Cole, G.M.7
-
8
-
-
84873114508
-
Silencing of triggering receptor expressed on myeloid cells-2 enhances the inflammatory responses of alveolar macrophages to lipopolysaccharide
-
Gao X., Dong Y., Liu Z., Niu B. Silencing of triggering receptor expressed on myeloid cells-2 enhances the inflammatory responses of alveolar macrophages to lipopolysaccharide. Mol. Med. Rep. 2013, 7:921-926.
-
(2013)
Mol. Med. Rep.
, vol.7
, pp. 921-926
-
-
Gao, X.1
Dong, Y.2
Liu, Z.3
Niu, B.4
-
9
-
-
84885761556
-
TREM2 and neurodegenerative disease
-
Guerreiro R., Hardy J. TREM2 and neurodegenerative disease. N. Engl. J. Med. 2013, 369:1569-1570.
-
(2013)
N. Engl. J. Med.
, vol.369
, pp. 1569-1570
-
-
Guerreiro, R.1
Hardy, J.2
-
10
-
-
84872057940
-
TREM2 variants in Alzheimer's disease
-
Alzheimer Genetic Analysis, G.
-
Guerreiro R., Wojtas A., Bras J., Carrasquillo M., Rogaeva E., Majounie E., Cruchaga C., Sassi C., Kauwe J.S., Younkin S., Hazrati L., Collinge J., Pocock J., Lashley T., Williams J., Lambert J.C., Amouyel P., Goate A., Rademakers R., Morgan K., Powell J., St George-Hyslop P., Singleton A., Hardy J. TREM2 variants in Alzheimer's disease. N. Engl. J. Med. 2013, 368:117-127. Alzheimer Genetic Analysis, G.
-
(2013)
N. Engl. J. Med.
, vol.368
, pp. 117-127
-
-
Guerreiro, R.1
Wojtas, A.2
Bras, J.3
Carrasquillo, M.4
Rogaeva, E.5
Majounie, E.6
Cruchaga, C.7
Sassi, C.8
Kauwe, J.S.9
Younkin, S.10
Hazrati, L.11
Collinge, J.12
Pocock, J.13
Lashley, T.14
Williams, J.15
Lambert, J.C.16
Amouyel, P.17
Goate, A.18
Rademakers, R.19
Morgan, K.20
Powell, J.21
St George-Hyslop, P.22
Singleton, A.23
Hardy, J.24
more..
-
11
-
-
33746875981
-
Cutting edge: inhibition of TLR and FcR responses in macrophages by triggering receptor expressed on myeloid cells (TREM)-2 and DAP12
-
Hamerman J.A., Jarjoura J.R., Humphrey M.B., Nakamura M.C., Seaman W.E., Lanier L.L. Cutting edge: inhibition of TLR and FcR responses in macrophages by triggering receptor expressed on myeloid cells (TREM)-2 and DAP12. J. Immunol. 2006, 177:2051-2055.
-
(2006)
J. Immunol.
, vol.177
, pp. 2051-2055
-
-
Hamerman, J.A.1
Jarjoura, J.R.2
Humphrey, M.B.3
Nakamura, M.C.4
Seaman, W.E.5
Lanier, L.L.6
-
12
-
-
84926370173
-
Neuroinflammation in Alzheimer's disease
-
Heneka M.T., Carson M.J., El Khoury J., Landreth G.E., Brosseron F., Feinstein D.L., Jacobs A.H., Wyss-Coray T., Vitorica J., Ransohoff R.M., Herrup K., Frautschy S.A., Finsen B., Brown G.C., Verkhratsky A., Yamanaka K., Koistinaho J., Latz E., Halle A., Petzold G.C., Town T., Morgan D., Shinohara M.L., Perry V.H., Holmes C., Bazan N.G., Brooks D.J., Hunot S., Joseph B., Deigendesch N., Garaschuk O., Boddeke E., Dinarello C.A., Breitner J.C., Cole G.M., Golenbock D.T., Kummer M.P. Neuroinflammation in Alzheimer's disease. Lancet Neurol. 2015, 14:388-405.
-
(2015)
Lancet Neurol.
, vol.14
, pp. 388-405
-
-
Heneka, M.T.1
Carson, M.J.2
El Khoury, J.3
Landreth, G.E.4
Brosseron, F.5
Feinstein, D.L.6
Jacobs, A.H.7
Wyss-Coray, T.8
Vitorica, J.9
Ransohoff, R.M.10
Herrup, K.11
Frautschy, S.A.12
Finsen, B.13
Brown, G.C.14
Verkhratsky, A.15
Yamanaka, K.16
Koistinaho, J.17
Latz, E.18
Halle, A.19
Petzold, G.C.20
Town, T.21
Morgan, D.22
Shinohara, M.L.23
Perry, V.H.24
Holmes, C.25
Bazan, N.G.26
Brooks, D.J.27
Hunot, S.28
Joseph, B.29
Deigendesch, N.30
Garaschuk, O.31
Boddeke, E.32
Dinarello, C.A.33
Breitner, J.C.34
Cole, G.M.35
Golenbock, D.T.36
Kummer, M.P.37
more..
-
13
-
-
65649114773
-
A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia
-
Hsieh C.L., Koike M., Spusta S.C., Niemi E.C., Yenari M., Nakamura M.C., Seaman W.E. A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia. J. Neurochem. 2009, 109:1144-1156.
-
(2009)
J. Neurochem.
, vol.109
, pp. 1144-1156
-
-
Hsieh, C.L.1
Koike, M.2
Spusta, S.C.3
Niemi, E.C.4
Yenari, M.5
Nakamura, M.C.6
Seaman, W.E.7
-
14
-
-
84930084373
-
Antiparallel beta-sheet structure within the C-Terminal region of 42-Residue Alzheimer's amyloid-beta peptides when they form 150-kDa oligomers
-
Huang D., Zimmerman M.I., Martin P.K., Nix A.J., Rosenberry T.L., Paravastu A.K. Antiparallel beta-sheet structure within the C-Terminal region of 42-Residue Alzheimer's amyloid-beta peptides when they form 150-kDa oligomers. J. Mol. Biol. 2015, 427:2319-2328.
-
(2015)
J. Mol. Biol.
, vol.427
, pp. 2319-2328
-
-
Huang, D.1
Zimmerman, M.I.2
Martin, P.K.3
Nix, A.J.4
Rosenberry, T.L.5
Paravastu, A.K.6
-
15
-
-
84855221945
-
TREM-2, triggering receptor expressed on myeloid cell-2, negatively regulates TLR responses in dendritic cells
-
Ito H., Hamerman J.A. TREM-2, triggering receptor expressed on myeloid cell-2, negatively regulates TLR responses in dendritic cells. Eur. J. Immunol. 2012, 42:176-185.
-
(2012)
Eur. J. Immunol.
, vol.42
, pp. 176-185
-
-
Ito, H.1
Hamerman, J.A.2
-
16
-
-
84924737031
-
TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models
-
Jay T.R., Miller C.M., Cheng P.J., Graham L.C., Bemiller S., Broihier M.L., Xu G., Margevicius D., Karlo J.C., Sousa G.L., Cotleur A.C., Butovsky O., Bekris L., Staugaitis S.M., Leverenz J.B., Pimplikar S.W., Landreth G.E., Howell G.R., Ransohoff R.M., Lamb B.T. TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models. J. Exp. Med. 2015, 212:287-295.
-
(2015)
J. Exp. Med.
, vol.212
, pp. 287-295
-
-
Jay, T.R.1
Miller, C.M.2
Cheng, P.J.3
Graham, L.C.4
Bemiller, S.5
Broihier, M.L.6
Xu, G.7
Margevicius, D.8
Karlo, J.C.9
Sousa, G.L.10
Cotleur, A.C.11
Butovsky, O.12
Bekris, L.13
Staugaitis, S.M.14
Leverenz, J.B.15
Pimplikar, S.W.16
Landreth, G.E.17
Howell, G.R.18
Ransohoff, R.M.19
Lamb, B.T.20
more..
-
17
-
-
84880923645
-
TREM2 in Alzheimer's disease
-
Jiang T., Yu J.T., Zhu X.C., Tan L. TREM2 in Alzheimer's disease. Mol. Neurobiol. 2013, 48:180-185.
-
(2013)
Mol. Neurobiol.
, vol.48
, pp. 180-185
-
-
Jiang, T.1
Yu, J.T.2
Zhu, X.C.3
Tan, L.4
-
18
-
-
84903362065
-
Triggering receptor expressed on myeloid cells 2 knockdown exacerbates aging-related neuroinflammation and cognitive deficiency in senescence-accelerated mouse prone 8 mice
-
Jiang T., Yu J.T., Zhu X.C., Tan M.S., Gu L.Z., Zhang Y.D., Tan L. Triggering receptor expressed on myeloid cells 2 knockdown exacerbates aging-related neuroinflammation and cognitive deficiency in senescence-accelerated mouse prone 8 mice. Neurobiol. Aging 2014, 35:1243-1251.
-
(2014)
Neurobiol. Aging
, vol.35
, pp. 1243-1251
-
-
Jiang, T.1
Yu, J.T.2
Zhu, X.C.3
Tan, M.S.4
Gu, L.Z.5
Zhang, Y.D.6
Tan, L.7
-
19
-
-
84872088087
-
Variant of TREM2 associated with the risk of Alzheimer's disease
-
Jonsson T., Stefansson H., Steinberg S., Jonsdottir I., Jonsson P.V., Snaedal J., Bjornsson S., Huttenlocher J., Levey A.I., Lah J.J., Rujescu D., Hampel H., Giegling I., Andreassen O.A., Engedal K., Ulstein I., Djurovic S., Ibrahim-Verbaas C., Hofman A., Ikram M.A., van Duijn C.M., Thorsteinsdottir U., Kong A., Stefansson K. Variant of TREM2 associated with the risk of Alzheimer's disease. N. Engl. J. Med. 2013, 368:107-116.
-
(2013)
N. Engl. J. Med.
, vol.368
, pp. 107-116
-
-
Jonsson, T.1
Stefansson, H.2
Steinberg, S.3
Jonsdottir, I.4
Jonsson, P.V.5
Snaedal, J.6
Bjornsson, S.7
Huttenlocher, J.8
Levey, A.I.9
Lah, J.J.10
Rujescu, D.11
Hampel, H.12
Giegling, I.13
Andreassen, O.A.14
Engedal, K.15
Ulstein, I.16
Djurovic, S.17
Ibrahim-Verbaas, C.18
Hofman, A.19
Ikram, M.A.20
van Duijn, C.M.21
Thorsteinsdottir, U.22
Kong, A.23
Stefansson, K.24
more..
-
20
-
-
79955605102
-
Physiology of microglia
-
Kettenmann H., Hanisch U.K., Noda M., Verkhratsky A. Physiology of microglia. Physiol. Rev. 2011, 91:461-553.
-
(2011)
Physiol. Rev.
, vol.91
, pp. 461-553
-
-
Kettenmann, H.1
Hanisch, U.K.2
Noda, M.3
Verkhratsky, A.4
-
21
-
-
33646485691
-
Trem-like transcript 2 is expressed on cells of the myeloid/granuloid and B lymphoid lineage and is up-regulated in response to inflammation
-
King R.G., Herrin B.R., Justement L.B. Trem-like transcript 2 is expressed on cells of the myeloid/granuloid and B lymphoid lineage and is up-regulated in response to inflammation. J. Immunol. 2006, 176:6012-6021.
-
(2006)
J. Immunol.
, vol.176
, pp. 6012-6021
-
-
King, R.G.1
Herrin, B.R.2
Justement, L.B.3
-
23
-
-
84907173621
-
Temporal gene profiling of the 5XFAD transgenic mouse model highlights the importance of microglial activation in Alzheimer's disease
-
Landel V., Baranger K., Virard I., Loriod B., Khrestchatisky M., Rivera S., Benech P., Feron F. Temporal gene profiling of the 5XFAD transgenic mouse model highlights the importance of microglial activation in Alzheimer's disease. Mol. Neurodegener. 2014, 9:33.
-
(2014)
Mol. Neurodegener.
, vol.9
, pp. 33
-
-
Landel, V.1
Baranger, K.2
Virard, I.3
Loriod, B.4
Khrestchatisky, M.5
Rivera, S.6
Benech, P.7
Feron, F.8
-
24
-
-
0025220976
-
Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain
-
Lawson L.J., Perry V.H., Dri P., Gordon S. Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain. Neuroscience 1990, 39:151-170.
-
(1990)
Neuroscience
, vol.39
, pp. 151-170
-
-
Lawson, L.J.1
Perry, V.H.2
Dri, P.3
Gordon, S.4
-
25
-
-
77956955758
-
The role of microglia in amyloid clearance from the AD brain
-
Lee C.Y., Landreth G.E. The role of microglia in amyloid clearance from the AD brain. J. Neural. Transm. 2010, 117:949-960.
-
(2010)
J. Neural. Transm.
, vol.117
, pp. 949-960
-
-
Lee, C.Y.1
Landreth, G.E.2
-
26
-
-
0028200868
-
Macrophage colony-stimulating factor mediates astrocyte-induced microglial ramification in human fetal central nervous system culture
-
Liu W., Brosnan C.F., Dickson D.W., Lee S.C. Macrophage colony-stimulating factor mediates astrocyte-induced microglial ramification in human fetal central nervous system culture. Am. J. Pathol. 1994, 145:48-53.
-
(1994)
Am. J. Pathol.
, vol.145
, pp. 48-53
-
-
Liu, W.1
Brosnan, C.F.2
Dickson, D.W.3
Lee, S.C.4
-
27
-
-
0037119422
-
Accelerated phagocytosis of amyloid-beta by mouse and human microglia overexpressing the macrophage colony-stimulating factor receptor
-
Mitrasinovic O.M., Murphy G.M. Accelerated phagocytosis of amyloid-beta by mouse and human microglia overexpressing the macrophage colony-stimulating factor receptor. J. Biol. Chem. 2002, 277:29889-29896.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 29889-29896
-
-
Mitrasinovic, O.M.1
Murphy, G.M.2
-
28
-
-
77957268367
-
Microglia: proliferation and activation driven by the P2X7 receptor
-
Monif M., Burnstock G., Williams D.A. Microglia: proliferation and activation driven by the P2X7 receptor. Int. J. Biochem. Cell Biol. 2010, 42:1753-1756.
-
(2010)
Int. J. Biochem. Cell Biol.
, vol.42
, pp. 1753-1756
-
-
Monif, M.1
Burnstock, G.2
Williams, D.A.3
-
29
-
-
84897954445
-
Microglial dysfunction in brain aging and Alzheimer's disease
-
Mosher K.I., Wyss-Coray T. Microglial dysfunction in brain aging and Alzheimer's disease. Biochem. Pharmacol. 2014, 88:594-604.
-
(2014)
Biochem. Pharmacol.
, vol.88
, pp. 594-604
-
-
Mosher, K.I.1
Wyss-Coray, T.2
-
30
-
-
60849109512
-
TREM-2 (triggering receptor expressed on myeloid cells 2) is a phagocytic receptor for bacteria
-
N'Diaye E.N., Branda C.S., Branda S.S., Nevarez L., Colonna M., Lowell C., Hamerman J.A., Seaman W.E. TREM-2 (triggering receptor expressed on myeloid cells 2) is a phagocytic receptor for bacteria. J. Cell Biol. 2009, 184:215-223.
-
(2009)
J. Cell Biol.
, vol.184
, pp. 215-223
-
-
N'Diaye, E.N.1
Branda, C.S.2
Branda, S.S.3
Nevarez, L.4
Colonna, M.5
Lowell, C.6
Hamerman, J.A.7
Seaman, W.E.8
-
31
-
-
33847625914
-
Essential role of the microglial triggering receptor expressed on myeloid cells-2 (TREM2) for central nervous tissue immune homeostasis
-
Neumann H., Takahashi K. Essential role of the microglial triggering receptor expressed on myeloid cells-2 (TREM2) for central nervous tissue immune homeostasis. J. Neuroimmunol. 2007, 184:92-99.
-
(2007)
J. Neuroimmunol.
, vol.184
, pp. 92-99
-
-
Neumann, H.1
Takahashi, K.2
-
32
-
-
67049159505
-
Is Alzheimer's disease a result of presynaptic failure? Synaptic dysfunctions induced by oligomeric beta-amyloid
-
Nimmrich V., Ebert U. Is Alzheimer's disease a result of presynaptic failure? Synaptic dysfunctions induced by oligomeric beta-amyloid. Rev. Neurosci. 2009, 20:1-12.
-
(2009)
Rev. Neurosci.
, vol.20
, pp. 1-12
-
-
Nimmrich, V.1
Ebert, U.2
-
33
-
-
84863239847
-
TREM2 and beta-catenin regulate bone homeostasis by controlling the rate of osteoclastogenesis
-
Otero K., Shinohara M., Zhao H., Cella M., Gilfillan S., Colucci A., Faccio R., Ross F.P., Teitelbaum S.L., Takayanagi H., Colonna M. TREM2 and beta-catenin regulate bone homeostasis by controlling the rate of osteoclastogenesis. J. Immunol. 2012, 188:2612-2621.
-
(2012)
J. Immunol.
, vol.188
, pp. 2612-2621
-
-
Otero, K.1
Shinohara, M.2
Zhao, H.3
Cella, M.4
Gilfillan, S.5
Colucci, A.6
Faccio, R.7
Ross, F.P.8
Teitelbaum, S.L.9
Takayanagi, H.10
Colonna, M.11
-
34
-
-
84940731281
-
TREM2 in CNS homeostasis and neurodegenerative disease
-
Painter M.M., Atagi Y., Liu C.C., Rademakers R., Xu H., Fryer J.D., Bu G. TREM2 in CNS homeostasis and neurodegenerative disease. Mol. Neurodegener. 2015, 10:43.
-
(2015)
Mol. Neurodegener.
, vol.10
, pp. 43
-
-
Painter, M.M.1
Atagi, Y.2
Liu, C.C.3
Rademakers, R.4
Xu, H.5
Fryer, J.D.6
Bu, G.7
-
35
-
-
77953819536
-
TREM2- and DAP12-dependent activation of PI3K requires DAP10 and is inhibited by SHIP1
-
Peng Q., Malhotra S., Torchia J.A., Kerr W.G., Coggeshall K.M., Humphrey M.B. TREM2- and DAP12-dependent activation of PI3K requires DAP10 and is inhibited by SHIP1. Sci. Signal. 2010, 3:ra38.
-
(2010)
Sci. Signal.
, vol.3
, pp. ra38
-
-
Peng, Q.1
Malhotra, S.2
Torchia, J.A.3
Kerr, W.G.4
Coggeshall, K.M.5
Humphrey, M.B.6
-
36
-
-
0025095717
-
Morphologic association between microglia and senile plaque amyloid in Alzheimer's disease
-
Perlmutter L.S., Barron E., Chui H.C. Morphologic association between microglia and senile plaque amyloid in Alzheimer's disease. Neurosci. Lett. 1990, 119:32-36.
-
(1990)
Neurosci. Lett.
, vol.119
, pp. 32-36
-
-
Perlmutter, L.S.1
Barron, E.2
Chui, H.C.3
-
37
-
-
77956537707
-
Microglia and neuroprotection: from in vitro studies to therapeutic applications
-
Polazzi E., Monti B. Microglia and neuroprotection: from in vitro studies to therapeutic applications. Prog. Neurobiol. 2010, 92:293-315.
-
(2010)
Prog. Neurobiol.
, vol.92
, pp. 293-315
-
-
Polazzi, E.1
Monti, B.2
-
38
-
-
67650966680
-
Microglial physiology: unique stimuli, specialized responses
-
Ransohoff R.M., Perry V.H. Microglial physiology: unique stimuli, specialized responses. Annu. Rev. Immunol. 2009, 27:119-145.
-
(2009)
Annu. Rev. Immunol.
, vol.27
, pp. 119-145
-
-
Ransohoff, R.M.1
Perry, V.H.2
-
39
-
-
84990982100
-
Interleukin-1beta causes excitotoxic neurodegeneration and multiple sclerosis disease progression by activating the apoptotic protein p53
-
Rossi S., Motta C., Studer V., Macchiarulo G., Volpe E., Barbieri F., Ruocco G., Buttari F., Finardi A., Mancino R., Weiss S., Battistini L., Martino G., Furlan R., Drulovic J., Centonze D. Interleukin-1beta causes excitotoxic neurodegeneration and multiple sclerosis disease progression by activating the apoptotic protein p53. Mol. Neurodegener. 2014, 9:56.
-
(2014)
Mol. Neurodegener.
, vol.9
, pp. 56
-
-
Rossi, S.1
Motta, C.2
Studer, V.3
Macchiarulo, G.4
Volpe, E.5
Barbieri, F.6
Ruocco, G.7
Buttari, F.8
Finardi, A.9
Mancino, R.10
Weiss, S.11
Battistini, L.12
Martino, G.13
Furlan, R.14
Drulovic, J.15
Centonze, D.16
-
40
-
-
67449119394
-
The surface-exposed chaperone, Hsp60, is an agonist of the microglial TREM2 receptor
-
Stefano L., Racchetti G., Bianco F., Passini N., Gupta R.S., Panina Bordignon P., Meldolesi J. The surface-exposed chaperone, Hsp60, is an agonist of the microglial TREM2 receptor. J. Neurochem. 2009, 110:284-294.
-
(2009)
J. Neurochem.
, vol.110
, pp. 284-294
-
-
Stefano, L.1
Racchetti, G.2
Bianco, F.3
Passini, N.4
Gupta, R.S.5
Panina Bordignon, P.6
Meldolesi, J.7
-
41
-
-
3042845492
-
Microglia and Alzheimer's disease pathogenesis
-
Streit W.J. Microglia and Alzheimer's disease pathogenesis. J. Neurosci. Res. 2004, 77:1-8.
-
(2004)
J. Neurosci. Res.
, vol.77
, pp. 1-8
-
-
Streit, W.J.1
-
42
-
-
84878135249
-
TREM-2 promotes host resistance against Pseudomonas aeruginosa infection by suppressing corneal inflammation via a PI3K/Akt signaling pathway
-
Sun M., Zhu M., Chen K., Nie X., Deng Q., Hazlett L.D., Wu Y., Li M., Wu M., Huang X. TREM-2 promotes host resistance against Pseudomonas aeruginosa infection by suppressing corneal inflammation via a PI3K/Akt signaling pathway. Invest. Ophthalmol. Vis. Sci. 2013, 54:3451-3462.
-
(2013)
Invest. Ophthalmol. Vis. Sci.
, vol.54
, pp. 3451-3462
-
-
Sun, M.1
Zhu, M.2
Chen, K.3
Nie, X.4
Deng, Q.5
Hazlett, L.D.6
Wu, Y.7
Li, M.8
Wu, M.9
Huang, X.10
-
43
-
-
34247500821
-
TREM2-transduced myeloid precursors mediate nervous tissue debris clearance and facilitate recovery in an animal model of multiple sclerosis
-
Takahashi K., Prinz M., Stagi M., Chechneva O., Neumann H. TREM2-transduced myeloid precursors mediate nervous tissue debris clearance and facilitate recovery in an animal model of multiple sclerosis. PLoS Med. 2007, 4:e124.
-
(2007)
PLoS Med.
, vol.4
, pp. e124
-
-
Takahashi, K.1
Prinz, M.2
Stagi, M.3
Chechneva, O.4
Neumann, H.5
-
44
-
-
14244268775
-
Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2
-
Takahashi K., Rochford C.D., Neumann H. Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2. J. Exp. Med. 2005, 201:647-657.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 647-657
-
-
Takahashi, K.1
Rochford, C.D.2
Neumann, H.3
-
45
-
-
84920842347
-
Oligomeric abeta-induced synaptic dysfunction in Alzheimer's disease
-
Tu S., Okamoto S., Lipton S.A., Xu H. Oligomeric abeta-induced synaptic dysfunction in Alzheimer's disease. Mol. Neurodegener. 2014, 9:48.
-
(2014)
Mol. Neurodegener.
, vol.9
, pp. 48
-
-
Tu, S.1
Okamoto, S.2
Lipton, S.A.3
Xu, H.4
-
46
-
-
33748517428
-
Cutting edge: TREM-2 attenuates macrophage activation
-
Turnbull I.R., Gilfillan S., Cella M., Aoshi T., Miller M., Piccio L., Hernandez M., Colonna M. Cutting edge: TREM-2 attenuates macrophage activation. J. Immunol. 2006, 177:3520-3524.
-
(2006)
J. Immunol.
, vol.177
, pp. 3520-3524
-
-
Turnbull, I.R.1
Gilfillan, S.2
Cella, M.3
Aoshi, T.4
Miller, M.5
Piccio, L.6
Hernandez, M.7
Colonna, M.8
-
47
-
-
84925464993
-
TREM2 lipid sensing sustains the microglial response in an Alzheimer's disease model
-
Wang Y., Cella M., Mallinson K., Ulrich J.D., Young K.L., Robinette M.L., Gilfillan S., Krishnan G.M., Sudhakar S., Zinselmeyer B.H., Holtzman D.M., Cirrito J.R., Colonna M. TREM2 lipid sensing sustains the microglial response in an Alzheimer's disease model. Cell 2015, 160:1061-1071.
-
(2015)
Cell
, vol.160
, pp. 1061-1071
-
-
Wang, Y.1
Cella, M.2
Mallinson, K.3
Ulrich, J.D.4
Young, K.L.5
Robinette, M.L.6
Gilfillan, S.7
Krishnan, G.M.8
Sudhakar, S.9
Zinselmeyer, B.H.10
Holtzman, D.M.11
Cirrito, J.R.12
Colonna, M.13
-
48
-
-
77953845018
-
Excitotoxicity of TNFalpha derived from KA activated microglia on hippocampal neurons in vitro and in vivo
-
Zhu W., Zheng H., Shao X., Wang W., Yao Q., Li Z. Excitotoxicity of TNFalpha derived from KA activated microglia on hippocampal neurons in vitro and in vivo. J. Neurochem. 2010, 114:386-396.
-
(2010)
J. Neurochem.
, vol.114
, pp. 386-396
-
-
Zhu, W.1
Zheng, H.2
Shao, X.3
Wang, W.4
Yao, Q.5
Li, Z.6
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