Excitotoxicity of TNFα derived from KA activated microglia on hippocampal neurons in vitro and in vivo

Journal of Neurochemistry

Volumn 114, Issue 2, 2010, Pages 386-396

  Zhu, Wei ^a   Zheng, Honghua ^b   Shao, Xinli ^c   Wang, Wei ^d   Yao, Qing ^a   Li, Zhengli ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b XIAMEN UNIVERSITY   (China)

^c UNIVERSITY OF TEXAS AT DALLAS   (United States)

^d HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

apoptosis; excitotoxicity; hippocampus; kainic acid; microglia; tumor necrosis factor alpha

Indexed keywords

CALCIUM ION; CASPASE 3; INDUCIBLE NITRIC OXIDE SYNTHASE; KAINIC ACID; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; TUMOR NECROSIS FACTOR ALPHA; CALCIUM; CALCIUM CHANNEL; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NMDA RECEPTOR A1;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BRAIN NERVE CELL; CONTROLLED STUDY; CYTOKINE PRODUCTION; ELECTROPHYSIOLOGY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXCITOTOXICITY; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MICROGLIA; NEUROTOXICITY; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ACTION POTENTIAL; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CULTURE MEDIUM; DRUG EFFECT; GENETICS; METABOLISM; NERVE CELL; PATHOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

RATTUS;

ACTION POTENTIALS; ANIMALS; APOPTOSIS; CALCIUM; CALCIUM CHANNELS; CASPASE 3; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; HIPPOCAMPUS; KAINIC ACID; MICROGLIA; NEURONS; NITRIC OXIDE SYNTHASE TYPE II; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77953845018     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2010.06763.x     Document Type: Article

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