Triggering receptor expressed on myeloid cells 2 knockdown exacerbates aging-related neuroinflammation and cognitive deficiency in senescence-accelerated mouse prone 8 mice

Neurobiology of Aging

Volumn 35, Issue 6, 2014, Pages 1243-1251

  Jiang, Teng ^a   Yu, Jin Tai ^a,b,c   Zhu, Xi Chen ^a   Tan, Meng Shan ^c   Gu, Li Ze ^a   Zhang, Ying Dong ^d   Tan, Lan ^a,b,c  

^a NANJING MEDICAL UNIVERSITY   (China)

^b QINGDAO UNIVERSITY MEDICAL COLLEGE   (China)

^c OCEAN UNIVERSITY OF CHINA   (China)

^d NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Aging; Alzheimer's disease; Cognitive deficiency; Neuroinflammation; SAMP8; SAMR1; TREM2

Indexed keywords

INTERLEUKIN 6; MEMBRANE PROTEIN; SMALL INTERFERING RNA; SYNAPTOPHYSIN; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; AUTACOID; CYTOKINE; IMMUNOGLOBULIN RECEPTOR; INTERLEUKIN 10; TREM2 PROTEIN, MOUSE;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; COGNITIVE DEFECT; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; INNATE IMMUNITY; MALE; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SENESCENCE; UPREGULATION; ALZHEIMER DISEASE; ANIMAL; BRAIN; DISEASE COURSE; DOWN REGULATION; GENE SILENCING; GENETICS; METABOLISM; MOUSE MUTANT; NERVE CELL; PATHOLOGY; PHYSIOLOGY; SYNAPSE;

AGING; ALZHEIMER DISEASE; ANIMALS; BRAIN; COGNITION DISORDERS; CYTOKINES; DISEASE PROGRESSION; DOWN-REGULATION; GENE KNOCKDOWN TECHNIQUES; INFLAMMATION MEDIATORS; INTERLEUKIN-10; INTERLEUKIN-6; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, NEUROLOGIC MUTANTS; NEURONS; RECEPTORS, IMMUNOLOGIC; RNA, SMALL INTERFERING; SYNAPSES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84903362065     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2013.11.026     Document Type: Article

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