Safety evaluation of AB-LIFE® (Lactobacillus plantarum CECT 7527, 7528 and 7529): Antibiotic resistance and 90-day repeated-dose study in rats

Food and Chemical Toxicology

Volumn 92, Issue , 2016, Pages 117-128

  Mukerji, Pushkor ^a   Roper, Jason M ^a   Stahl, Buffy ^a   Smith, Amy B ^a   Burns, Frank ^a   Rae, Jessica Caverly ^a   Yeung, Nicolas ^a   Lyra, Anna ^a   Svärd, Laura ^a   Saarinen, Markku T ^a   Alhoniemi, Esa ^b   Ibarra, Alvin ^a   Ouwehand, Arthur C ^a  

^a DUPONT COMPANY   (United States)

^b DuPont Nutrition and Health ^*  (Finland)

Author keywords

Lactobacillus plantarum; Probiotic; Rats; Subchronic toxicity

Indexed keywords

BILE ACID; LACTIC ACID; PROBIOTIC AGENT; SHORT CHAIN FATTY ACID; STEROL;

ANIMAL EXPERIMENT; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENETICS; BACTERIAL GENOME; BACTERIAL STRAIN; COLONY FORMING UNIT; CONTROLLED STUDY; DRUG SAFETY; FECES ANALYSIS; FEMALE; GASTROINTESTINAL TRACT; LACTOBACILLUS PLANTARUM; MALE; NONHUMAN; RAT; TOXICITY TESTING; ANIMAL; BACTERIAL GENE; CHEMISTRY; DRUG EFFECTS; EVALUATION STUDY; FECES; GENE EXPRESSION REGULATION; GENETICS; GENOMICS; HIGH THROUGHPUT SEQUENCING; HUMAN; MICROBIOLOGY; NO-OBSERVED-ADVERSE-EFFECT LEVEL; ORAL DRUG ADMINISTRATION; PHYSIOLOGY; PROCEDURES; SAFETY;

ADMINISTRATION, ORAL; ANIMALS; DRUG RESISTANCE, MICROBIAL; FECES; FEMALE; GASTROINTESTINAL TRACT; GENE EXPRESSION REGULATION, BACTERIAL; GENES, BACTERIAL; GENOMICS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; LACTOBACILLUS PLANTARUM; MALE; NO-OBSERVED-ADVERSE-EFFECT LEVEL; PROBIOTICS; RATS; SAFETY; TOXICITY TESTS, SUBCHRONIC;

EID: 84962791874     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2016.03.018     Document Type: Article

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