-
1
-
-
79955622718
-
Priorities in Parkinson’s disease research
-
COI: 1:CAS:528:DC%2BC3MXlsVGltr4%3D, PID: 21532567
-
Meissner WG, Frasier M, Gasser T, Goetz CG, Lozano A, Piccini P, Obeso JA, Rascol O, Schapira A, Voon V, Weiner DM, Tison F, Bezard E (2011) Priorities in Parkinson’s disease research. Nat Rev Drug Discov 10:377–393
-
(2011)
Nat Rev Drug Discov
, vol.10
, pp. 377-393
-
-
Meissner, W.G.1
Frasier, M.2
Gasser, T.3
Goetz, C.G.4
Lozano, A.5
Piccini, P.6
Obeso, J.A.7
Rascol, O.8
Schapira, A.9
Voon, V.10
Weiner, D.M.11
Tison, F.12
Bezard, E.13
-
2
-
-
2542596183
-
Parkinson’s disease
-
COI: 1:CAS:528:DC%2BD2cXksVanu7k%3D, PID: 15172778
-
Samii A, Nutt JG, Ransom BR (2004) Parkinson’s disease. Lancet 363:1783–1793
-
(2004)
Lancet
, vol.363
, pp. 1783-1793
-
-
Samii, A.1
Nutt, J.G.2
Ransom, B.R.3
-
3
-
-
33749570292
-
Phosphorylation of Ser-129 is the dominant pathological modification of alpha-synuclein in familial and sporadic Lewy body disease
-
COI: 1:CAS:528:DC%2BD28XhtVahsb%2FI, PID: 16847063
-
Anderson JP, Walker DE, Goldstein JM, de Laat R, Banducci K, Caccavello RJ, Barbour R, Huang J, Kling K, Lee M, Diep L, Keim PS, Shen X, Chataway T, Schlossmacher MG, Seubert P, Schenk D, Sinha S, Gai WP, Chilcote TJ (2006) Phosphorylation of Ser-129 is the dominant pathological modification of alpha-synuclein in familial and sporadic Lewy body disease. J Biol Chem 281:29739–29752
-
(2006)
J Biol Chem
, vol.281
, pp. 29739-29752
-
-
Anderson, J.P.1
Walker, D.E.2
Goldstein, J.M.3
de Laat, R.4
Banducci, K.5
Caccavello, R.J.6
Barbour, R.7
Huang, J.8
Kling, K.9
Lee, M.10
Diep, L.11
Keim, P.S.12
Shen, X.13
Chataway, T.14
Schlossmacher, M.G.15
Seubert, P.16
Schenk, D.17
Sinha, S.18
Gai, W.P.19
Chilcote, T.J.20
more..
-
5
-
-
84893129338
-
The pathomechanisms underlying Parkinson’s disease
-
COI: 1:CAS:528:DC%2BC2cXht1Ort7o%3D, PID: 24471711
-
Jellinger KA (2014) The pathomechanisms underlying Parkinson’s disease. Expert Rev Neurother 14:199–215
-
(2014)
Expert Rev Neurother
, vol.14
, pp. 199-215
-
-
Jellinger, K.A.1
-
6
-
-
0141741347
-
Parkinson’s disease: mechanisms and models
-
COI: 1:CAS:528:DC%2BD3sXnsFait7o%3D, PID: 12971891
-
Dauer W, Przedborski S (2003) Parkinson’s disease: mechanisms and models. Neuron 39:889–909
-
(2003)
Neuron
, vol.39
, pp. 889-909
-
-
Dauer, W.1
Przedborski, S.2
-
7
-
-
84911423174
-
The prevalence of Parkinson’s disease: a systematic review and meta-analysis
-
PID: 24976103
-
Pringsheim T, Jette N, Frolkis A, Steeves TD (2014) The prevalence of Parkinson’s disease: a systematic review and meta-analysis. Mov Disord 29:1583–1590
-
(2014)
Mov Disord
, vol.29
, pp. 1583-1590
-
-
Pringsheim, T.1
Jette, N.2
Frolkis, A.3
Steeves, T.D.4
-
8
-
-
0034626747
-
Genetic pathways that regulate ageing in model organisms
-
COI: 1:CAS:528:DC%2BD3cXotFGksrs%3D, PID: 11089983
-
Guarente L, Kenyon C (2000) Genetic pathways that regulate ageing in model organisms. Nature 408:255–262
-
(2000)
Nature
, vol.408
, pp. 255-262
-
-
Guarente, L.1
Kenyon, C.2
-
9
-
-
2942564591
-
Sirtuins: Sir2-related NAD-dependent protein deacetylases
-
PID: 15128440
-
North BJ, Verdin E (2004) Sirtuins: Sir2-related NAD-dependent protein deacetylases. Genome Biol 5:224
-
(2004)
Genome Biol
, vol.5
, pp. 224
-
-
North, B.J.1
Verdin, E.2
-
10
-
-
33846583673
-
SIR2: a potential target for calorie restriction mimetics
-
COI: 1:CAS:528:DC%2BD2sXhtlSnsro%3D, PID: 17207661
-
Chen D, Guarente L (2007) SIR2: a potential target for calorie restriction mimetics. Trends Mol Med 13:64–71
-
(2007)
Trends Mol Med
, vol.13
, pp. 64-71
-
-
Chen, D.1
Guarente, L.2
-
11
-
-
0018293588
-
Activation of mating type genes by transposition in Saccharomyces cerevisiae
-
COI: 1:STN:280:DyaL3c%2Fls1OksA%3D%3D, PID: 388445
-
Klar AJ, Fogel S (1979) Activation of mating type genes by transposition in Saccharomyces cerevisiae. Proc Natl Acad Sci USA 76:4539–4543
-
(1979)
Proc Natl Acad Sci USA
, vol.76
, pp. 4539-4543
-
-
Klar, A.J.1
Fogel, S.2
-
12
-
-
84894489242
-
Do sirtuins promote mammalian longevity? A critical review on its relevance to the longevity effect induced by calorie restriction
-
COI: 1:CAS:528:DC%2BC3sXhtVehs77F, PID: 23661364
-
Park S, Mori R, Shimokawa I (2013) Do sirtuins promote mammalian longevity? A critical review on its relevance to the longevity effect induced by calorie restriction. Mol Cells 35:474–480
-
(2013)
Mol Cells
, vol.35
, pp. 474-480
-
-
Park, S.1
Mori, R.2
Shimokawa, I.3
-
13
-
-
84904751060
-
NAD+ and sirtuins in aging and disease
-
COI: 1:CAS:528:DC%2BC2cXnsVeqsr4%3D, PID: 24786309
-
Imai S, Guarente L (2014) NAD+ and sirtuins in aging and disease. Trends Cell Biol 24:464–471
-
(2014)
Trends Cell Biol
, vol.24
, pp. 464-471
-
-
Imai, S.1
Guarente, L.2
-
14
-
-
61549117497
-
Incidence and remaining lifetime risk of Parkinson disease in advanced age
-
PID: 19188574
-
Driver JA, Logroscino G, Gaziano JM, Kurth T (2009) Incidence and remaining lifetime risk of Parkinson disease in advanced age. Neurology 72:432–438
-
(2009)
Neurology
, vol.72
, pp. 432-438
-
-
Driver, J.A.1
Logroscino, G.2
Gaziano, J.M.3
Kurth, T.4
-
15
-
-
0033214237
-
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
-
COI: 1:CAS:528:DyaK1MXmvFOitbc%3D, PID: 10521401
-
Kaeberlein M, McVey M, Guarente L (1999) The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev 13:2570–2580
-
(1999)
Genes Dev
, vol.13
, pp. 2570-2580
-
-
Kaeberlein, M.1
McVey, M.2
Guarente, L.3
-
16
-
-
0035913911
-
Negative control of p53 by Sir2alpha promotes cell survival under stress
-
COI: 1:CAS:528:DC%2BD3MXotVSntro%3D, PID: 11672522
-
Luo J, Nikolaev AY, Imai S, Chen D, Su F, Shiloh A, Guarente L, Gu W (2001) Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell 107:137–148
-
(2001)
Cell
, vol.107
, pp. 137-148
-
-
Luo, J.1
Nikolaev, A.Y.2
Imai, S.3
Chen, D.4
Su, F.5
Shiloh, A.6
Guarente, L.7
Gu, W.8
-
17
-
-
4344640637
-
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma (vol 429, p 771, 2004)
-
COI: 1:CAS:528:DC%2BD2cXmslCmsrw%3D
-
Picard F, Kurtev M, Chung N, Topark-Ngarm A, Senawong T, de Oliveira RM, Leid M, McBurney MW, Guarente L (2004) Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma (vol 429, p 771, 2004). Nature 430:921
-
(2004)
Nature
, vol.430
, pp. 921
-
-
Picard, F.1
Kurtev, M.2
Chung, N.3
Topark-Ngarm, A.4
Senawong, T.5
de Oliveira, R.M.6
Leid, M.7
McBurney, M.W.8
Guarente, L.9
-
18
-
-
84895835925
-
Forever young: SIRT3 a shield against mitochondrial meltdown, aging, and neurodegeneration
-
PID: 24046746
-
Kincaid B, Bossy-Wetzel E (2013) Forever young: SIRT3 a shield against mitochondrial meltdown, aging, and neurodegeneration. Front Aging Neurosci 5:48
-
(2013)
Front Aging Neurosci
, vol.5
, pp. 48
-
-
Kincaid, B.1
Bossy-Wetzel, E.2
-
19
-
-
84879026707
-
SIRT3 regulation of mitochondrial oxidative stress
-
COI: 1:CAS:528:DC%2BC38Xhs1Gktr3E, PID: 22964489
-
Bause AS, Haigis MC (2013) SIRT3 regulation of mitochondrial oxidative stress. Exp Gerontol 48:634–639
-
(2013)
Exp Gerontol
, vol.48
, pp. 634-639
-
-
Bause, A.S.1
Haigis, M.C.2
-
20
-
-
84857628087
-
The role of SIRT3 in mitochondrial homeostasis and cardiac adaptation to hypertrophy and aging
-
COI: 1:CAS:528:DC%2BC38XjtlSns7Y%3D, PID: 22119802
-
Sack MN (2012) The role of SIRT3 in mitochondrial homeostasis and cardiac adaptation to hypertrophy and aging. J Mol Cell Cardiol 52:520–525
-
(2012)
J Mol Cell Cardiol
, vol.52
, pp. 520-525
-
-
Sack, M.N.1
-
21
-
-
78651468722
-
Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction
-
COI: 1:CAS:528:DC%2BC3cXhsVygsLfI, PID: 21094524
-
Someya S, Yu W, Hallows WC, Xu J, Vann JM, Leeuwenburgh C, Tanokura M, Denu JM, Prolla TA (2010) Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction. Cell 143:802–812
-
(2010)
Cell
, vol.143
, pp. 802-812
-
-
Someya, S.1
Yu, W.2
Hallows, W.C.3
Xu, J.4
Vann, J.M.5
Leeuwenburgh, C.6
Tanokura, M.7
Denu, J.M.8
Prolla, T.A.9
-
22
-
-
79958041601
-
The SirT3 divining rod points to oxidative stress
-
COI: 1:CAS:528:DC%2BC3MXnsV2jtbw%3D, PID: 21658599
-
Bell EL, Guarente L (2011) The SirT3 divining rod points to oxidative stress. Mol Cell 42:561–568
-
(2011)
Mol Cell
, vol.42
, pp. 561-568
-
-
Bell, E.L.1
Guarente, L.2
-
23
-
-
10744232772
-
Variability of the SIRT3 gene, human silent information regulator Sir2 homologue, and survivorship in the elderly
-
COI: 1:CAS:528:DC%2BD3sXot12jsbk%3D, PID: 14580859
-
Rose G, Dato S, Altomare K, Bellizzi D, Garasto S, Greco V, Passarino G, Feraco E, Mari V, Barbi C, BonaFe M, Franceschi C, Tan Q, Boiko S, Yashin AI, De Benedictis G (2003) Variability of the SIRT3 gene, human silent information regulator Sir2 homologue, and survivorship in the elderly. Exp Gerontol 38:1065–1070
-
(2003)
Exp Gerontol
, vol.38
, pp. 1065-1070
-
-
Rose, G.1
Dato, S.2
Altomare, K.3
Bellizzi, D.4
Garasto, S.5
Greco, V.6
Passarino, G.7
Feraco, E.8
Mari, V.9
Barbi, C.10
BonaFe, M.11
Franceschi, C.12
Tan, Q.13
Boiko, S.14
Yashin, A.I.15
De Benedictis, G.16
-
24
-
-
84940451498
-
SIRT3 regulates progression and development of diseases of aging
-
COI: 1:CAS:528:DC%2BC2MXhtV2itrnN, PID: 26138757
-
McDonnell E, Peterson BS, Bomze HM, Hirschey MD (2015) SIRT3 regulates progression and development of diseases of aging. Trends Endocrinol Metab 26:486–492
-
(2015)
Trends Endocrinol Metab
, vol.26
, pp. 486-492
-
-
McDonnell, E.1
Peterson, B.S.2
Bomze, H.M.3
Hirschey, M.D.4
-
25
-
-
84891039686
-
SIRT3: As simple as it seems?
-
COI: 1:CAS:528:DC%2BC3sXitVSqtLjF, PID: 24192814
-
Lombard DB, Zwaans BM (2014) SIRT3: As simple as it seems? Gerontology 60:56–64
-
(2014)
Gerontology
, vol.60
, pp. 56-64
-
-
Lombard, D.B.1
Zwaans, B.M.2
-
26
-
-
84902119469
-
Pituitary adenylate cyclase-activating polypeptide protects against beta-amyloid toxicity
-
COI: 1:CAS:528:DC%2BC2cXmtVCgt7w%3D, PID: 24726470
-
Han P, Tang Z, Yin J, Maalouf M, Beach TG, Reiman EM, Shi J (2014) Pituitary adenylate cyclase-activating polypeptide protects against beta-amyloid toxicity. Neurobiol Aging 35:2064–2071
-
(2014)
Neurobiol Aging
, vol.35
, pp. 2064-2071
-
-
Han, P.1
Tang, Z.2
Yin, J.3
Maalouf, M.4
Beach, T.G.5
Reiman, E.M.6
Shi, J.7
-
27
-
-
79952353862
-
Neuronal Sirt3 protects against excitotoxic injury in mouse cortical neuron culture
-
COI: 1:CAS:528:DC%2BC3MXjtFejtbo%3D, PID: 21390294
-
Kim SH, Lu HF, Alano CC (2011) Neuronal Sirt3 protects against excitotoxic injury in mouse cortical neuron culture. PLoS One 6:e14731
-
(2011)
PLoS One
, vol.6
, pp. e14731
-
-
Kim, S.H.1
Lu, H.F.2
Alano, C.C.3
-
28
-
-
84863794891
-
trans-(-)-epsilon-Viniferin increases mitochondrial sirtuin 3 (SIRT3), activates AMP-activated protein kinase (AMPK), and protects cells in models of Huntington disease
-
COI: 1:CAS:528:DC%2BC38XhtVWgtLnF, PID: 22648412
-
Fu J, Jin J, Cichewicz RH, Hageman SA, Ellis TK, Xiang L, Peng Q, Jiang M, Arbez N, Hotaling K, Ross CA, Duan W (2012) trans-(-)-epsilon-Viniferin increases mitochondrial sirtuin 3 (SIRT3), activates AMP-activated protein kinase (AMPK), and protects cells in models of Huntington disease. J Biol Chem 287:24460–24472
-
(2012)
J Biol Chem
, vol.287
, pp. 24460-24472
-
-
Fu, J.1
Jin, J.2
Cichewicz, R.H.3
Hageman, S.A.4
Ellis, T.K.5
Xiang, L.6
Peng, Q.7
Jiang, M.8
Arbez, N.9
Hotaling, K.10
Ross, C.A.11
Duan, W.12
-
29
-
-
84872683148
-
Mutant SOD1G93A triggers mitochondrial fragmentation in spinal cord motor neurons: neuroprotection by SIRT3 and PGC-1alpha
-
COI: 1:CAS:528:DC%2BC3sXhs1Cgu78%3D, PID: 22819776
-
Song W, Song Y, Kincaid B, Bossy B, Bossy-Wetzel E (2013) Mutant SOD1G93A triggers mitochondrial fragmentation in spinal cord motor neurons: neuroprotection by SIRT3 and PGC-1alpha. Neurobiol Dis 51:72–81
-
(2013)
Neurobiol Dis
, vol.51
, pp. 72-81
-
-
Song, W.1
Song, Y.2
Kincaid, B.3
Bossy, B.4
Bossy-Wetzel, E.5
-
30
-
-
84925487114
-
SIRT3 attenuates MPTP-induced nigrostriatal degeneration via enhancing mitochondrial antioxidant capacity
-
COI: 1:CAS:528:DC%2BC2MXmslChsw%3D%3D, PID: 25555707
-
Liu L, Peritore C, Ginsberg J, Kayhan M, Donmez G (2015) SIRT3 attenuates MPTP-induced nigrostriatal degeneration via enhancing mitochondrial antioxidant capacity. Neurochem Res 40:600–608
-
(2015)
Neurochem Res
, vol.40
, pp. 600-608
-
-
Liu, L.1
Peritore, C.2
Ginsberg, J.3
Kayhan, M.4
Donmez, G.5
-
31
-
-
0033681149
-
Chronic systemic pesticide exposure reproduces features of Parkinson’s disease
-
COI: 1:CAS:528:DC%2BD3cXosVGgsbg%3D, PID: 11100151
-
Betarbet R, Sherer TB, MacKenzie G, Garcia-Osuna M, Panov AV, Greenamyre JT (2000) Chronic systemic pesticide exposure reproduces features of Parkinson’s disease. Nat Neurosci 3:1301–1306
-
(2000)
Nat Neurosci
, vol.3
, pp. 1301-1306
-
-
Betarbet, R.1
Sherer, T.B.2
MacKenzie, G.3
Garcia-Osuna, M.4
Panov, A.V.5
Greenamyre, J.T.6
-
32
-
-
0032490114
-
Inhibitors of NADH-ubiquinone reductase: an overview
-
COI: 1:CAS:528:DyaK1cXis1Cltr4%3D, PID: 9593904
-
Degli Esposti M (1998) Inhibitors of NADH-ubiquinone reductase: an overview. Biochim Biophys Acta 1364:222–235
-
(1998)
Biochim Biophys Acta
, vol.1364
, pp. 222-235
-
-
Degli Esposti, M.1
-
33
-
-
0033773407
-
In vivo labeling of mitochondrial complex I (NADH: ubiquinone oxidoreductase) in rat brain using [(3)H]dihydrorotenone
-
COI: 1:CAS:528:DC%2BD3cXotFKnt7o%3D, PID: 11080215
-
Talpade DJ, Greene JG, Higgins DS Jr, Greenamyre JT (2000) In vivo labeling of mitochondrial complex I (NADH: ubiquinone oxidoreductase) in rat brain using [(3)H]dihydrorotenone. J Neurochem 75:2611–2621
-
(2000)
J Neurochem
, vol.75
, pp. 2611-2621
-
-
Talpade, D.J.1
Greene, J.G.2
Higgins, D.S.3
Greenamyre, J.T.4
-
34
-
-
84871266643
-
Rotenone inhibits autophagic flux prior to inducing cell death
-
COI: 1:CAS:528:DC%2BC38XhtlCjsrjL, PID: 23259041
-
Mader BJ, Pivtoraiko VN, Flippo HM, Klocke BJ, Roth KA, Mangieri LR, Shacka JJ (2012) Rotenone inhibits autophagic flux prior to inducing cell death. ACS Chem Neurosci 3:1063–1072
-
(2012)
ACS Chem Neurosci
, vol.3
, pp. 1063-1072
-
-
Mader, B.J.1
Pivtoraiko, V.N.2
Flippo, H.M.3
Klocke, B.J.4
Roth, K.A.5
Mangieri, L.R.6
Shacka, J.J.7
-
35
-
-
84876445381
-
CNS SIRT3 expression is altered by reactive oxygen species and in Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BC38Xhslamu7fJ, PID: 23139766
-
Weir HJM, Murray TK, Kehoe PG, Love S, Verdin EM, O’Neill MJ, Lane JD, Balthasar N (2012) CNS SIRT3 expression is altered by reactive oxygen species and in Alzheimer’s disease. PLoS One 7:e48225
-
(2012)
PLoS One
, vol.7
, pp. e48225
-
-
Weir, H.J.M.1
Murray, T.K.2
Kehoe, P.G.3
Love, S.4
Verdin, E.M.5
O’Neill, M.J.6
Lane, J.D.7
Balthasar, N.8
-
36
-
-
33750361540
-
A century-old debate on protein aggregation and neurodegeneration enters the clinic
-
COI: 1:CAS:528:DC%2BD28XhtVyktbbM, PID: 17051203
-
Lansbury PT, Lashuel HA (2006) A century-old debate on protein aggregation and neurodegeneration enters the clinic. Nature 443:774–779
-
(2006)
Nature
, vol.443
, pp. 774-779
-
-
Lansbury, P.T.1
Lashuel, H.A.2
-
37
-
-
84894291922
-
alpha-Synuclein and mitochondrial dysfunction in Parkinson’s disease
-
COI: 1:CAS:528:DC%2BC3sXjsFejtLg%3D, PID: 23361255
-
Mullin S, Schapira A (2013) alpha-Synuclein and mitochondrial dysfunction in Parkinson’s disease. Mol Neurobiol 47:587–597
-
(2013)
Mol Neurobiol
, vol.47
, pp. 587-597
-
-
Mullin, S.1
Schapira, A.2
-
38
-
-
0030882856
-
Alpha-synuclein in Lewy bodies
-
COI: 1:CAS:528:DyaK2sXlslWru7o%3D, PID: 9278044
-
Spillantini MG, Schmidt ML, Lee VM, Trojanowski JQ, Jakes R, Goedert M (1997) Alpha-synuclein in Lewy bodies. Nature 388:839–840
-
(1997)
Nature
, vol.388
, pp. 839-840
-
-
Spillantini, M.G.1
Schmidt, M.L.2
Lee, V.M.3
Trojanowski, J.Q.4
Jakes, R.5
Goedert, M.6
-
39
-
-
38549169530
-
The two faces of protein misfolding: gain- and loss-of-function in neurodegenerative diseases
-
COI: 1:CAS:528:DC%2BD1cXhtVKrsr8%3D, PID: 18216876
-
Winklhofer KF, Tatzelt J, Haass C (2008) The two faces of protein misfolding: gain- and loss-of-function in neurodegenerative diseases. EMBO J 27:336–349
-
(2008)
EMBO J
, vol.27
, pp. 336-349
-
-
Winklhofer, K.F.1
Tatzelt, J.2
Haass, C.3
-
40
-
-
84872687901
-
Mitochondrial dysfunction and oxidative stress in Parkinson’s disease and monogenic parkinsonism
-
COI: 1:CAS:528:DC%2BC3sXhs1egt7g%3D, PID: 23064436
-
Hauser DN, Hastings TG (2013) Mitochondrial dysfunction and oxidative stress in Parkinson’s disease and monogenic parkinsonism. Neurobiol Dis 51:35–42
-
(2013)
Neurobiol Dis
, vol.51
, pp. 35-42
-
-
Hauser, D.N.1
Hastings, T.G.2
-
41
-
-
84894384733
-
The role of inflammatory and oxidative stress mechanisms in the pathogenesis of Parkinson’s disease: focus on astrocytes
-
PID: 23783559
-
Niranjan R (2013) The role of inflammatory and oxidative stress mechanisms in the pathogenesis of Parkinson’s disease: focus on astrocytes. Mol Neurobiol 49:28–38
-
(2013)
Mol Neurobiol
, vol.49
, pp. 28-38
-
-
Niranjan, R.1
-
42
-
-
0038043242
-
+ depletion and cell death induced by oxidative stress
-
COI: 1:CAS:528:DC%2BD3sXjs1KhsbY%3D, PID: 12626504
-
+ depletion and cell death induced by oxidative stress. J Biol Chem 278:18426–18433
-
(2003)
J Biol Chem
, vol.278
, pp. 18426-18433
-
-
Du, L.1
Zhang, X.2
Han, Y.Y.3
Burke, N.A.4
Kochanek, P.M.5
Watkins, S.C.6
Graham, S.H.7
Carcillo, J.A.8
Szabo, C.9
Clark, R.S.10
-
43
-
-
17144424946
-
SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes
-
COI: 1:CAS:528:DC%2BD2MXivV2kt7s%3D, PID: 15653680
-
Shi T, Wang F, Stieren E, Tong Q (2005) SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes. J Biol Chem 280:13560–13567
-
(2005)
J Biol Chem
, vol.280
, pp. 13560-13567
-
-
Shi, T.1
Wang, F.2
Stieren, E.3
Tong, Q.4
-
44
-
-
70349208608
-
Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice
-
COI: 1:CAS:528:DC%2BD1MXhtFWgs7%2FN, PID: 19652361
-
Sundaresan NR, Gupta M, Kim G, Rajamohan SB, Isbatan A, Gupta MP (2009) Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice. J Clin Invest 119:2758–2771
-
(2009)
J Clin Invest
, vol.119
, pp. 2758-2771
-
-
Sundaresan, N.R.1
Gupta, M.2
Kim, G.3
Rajamohan, S.B.4
Isbatan, A.5
Gupta, M.P.6
-
45
-
-
53549105529
-
SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70
-
COI: 1:CAS:528:DC%2BD1cXht1Cit7fE, PID: 18710944
-
Sundaresan NR, Samant SA, Pillai VB, Rajamohan SB, Gupta MP (2008) SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70. Mol Cell Biol 28:6384–6401
-
(2008)
Mol Cell Biol
, vol.28
, pp. 6384-6401
-
-
Sundaresan, N.R.1
Samant, S.A.2
Pillai, V.B.3
Rajamohan, S.B.4
Gupta, M.P.5
-
46
-
-
74049094817
-
SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress
-
COI: 1:CAS:528:DC%2BC3cXkvFKgs7s%3D, PID: 20129246
-
Kim HS, Patel K, Muldoon-Jacobs K, Bisht KS, Aykin-Burns N, Pennington JD, van der Meer R, Nguyen P, Savage J, Owens KM, Vassilopoulos A, Ozden O, Park SH, Singh KK, Abdulkadir SA, Spitz DR, Deng CX, Gius D (2010) SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress. Cancer Cell 17:41–52
-
(2010)
Cancer Cell
, vol.17
, pp. 41-52
-
-
Kim, H.S.1
Patel, K.2
Muldoon-Jacobs, K.3
Bisht, K.S.4
Aykin-Burns, N.5
Pennington, J.D.6
van der Meer, R.7
Nguyen, P.8
Savage, J.9
Owens, K.M.10
Vassilopoulos, A.11
Ozden, O.12
Park, S.H.13
Singh, K.K.14
Abdulkadir, S.A.15
Spitz, D.R.16
Deng, C.X.17
Gius, D.18
-
47
-
-
78649521247
-
Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation
-
COI: 1:CAS:528:DC%2BC3cXhsVyhs7jJ, PID: 21109198
-
Qiu X, Brown K, Hirschey MD, Verdin E, Chen D (2010) Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation. Cell Metab 12:662–667
-
(2010)
Cell Metab
, vol.12
, pp. 662-667
-
-
Qiu, X.1
Brown, K.2
Hirschey, M.D.3
Verdin, E.4
Chen, D.5
-
48
-
-
78650248160
-
Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress
-
COI: 1:CAS:528:DC%2BC3cXhsF2isbfK, PID: 21172655
-
Tao R, Coleman MC, Pennington JD, Ozden O, Park SH, Jiang H, Kim HS, Flynn CR, Hill S, Hayes McDonald W, Olivier AK, Spitz DR, Gius D (2010) Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress. Mol Cell 40:893–904
-
(2010)
Mol Cell
, vol.40
, pp. 893-904
-
-
Tao, R.1
Coleman, M.C.2
Pennington, J.D.3
Ozden, O.4
Park, S.H.5
Jiang, H.6
Kim, H.S.7
Flynn, C.R.8
Hill, S.9
Hayes McDonald, W.10
Olivier, A.K.11
Spitz, D.R.12
Gius, D.13
-
49
-
-
80051665640
-
Neuroprotective strategies involving ROS in Alzheimer disease
-
COI: 1:CAS:528:DC%2BC3MXhtVagtbjN, PID: 21130159
-
Dumont M, Beal MF (2011) Neuroprotective strategies involving ROS in Alzheimer disease. Free Radic Biol Med 51:1014–1026
-
(2011)
Free Radic Biol Med
, vol.51
, pp. 1014-1026
-
-
Dumont, M.1
Beal, M.F.2
-
50
-
-
84884879594
-
Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease
-
COI: 1:CAS:528:DC%2BC3sXhtVOqtg%3D%3D, PID: 23200807
-
Yan MH, Wang X, Zhu X (2013) Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease. Free Radic Biol Med 62:90–101
-
(2013)
Free Radic Biol Med
, vol.62
, pp. 90-101
-
-
Yan, M.H.1
Wang, X.2
Zhu, X.3
-
51
-
-
84901243996
-
Mitochondrial dysfunctions in Parkinson’s disease
-
PID: 24119854
-
Gautier CA, Corti O, Brice A (2013) Mitochondrial dysfunctions in Parkinson’s disease. Rev Neurol 170:339–343
-
(2013)
Rev Neurol
, vol.170
, pp. 339-343
-
-
Gautier, C.A.1
Corti, O.2
Brice, A.3
-
52
-
-
79957606041
-
Etiology and pathogenesis of Parkinson’s disease
-
PID: 21626550
-
Schapira AH, Jenner P (2011) Etiology and pathogenesis of Parkinson’s disease. Mov Disord 26:1049–1055
-
(2011)
Mov Disord
, vol.26
, pp. 1049-1055
-
-
Schapira, A.H.1
Jenner, P.2
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