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Volumn 11, Issue 3, 2016, Pages

Versatile trans-replication systems for chikungunya virus allow functional analysis and tagging of every replicase protein

Author keywords

[No Author keywords available]

Indexed keywords

ENHANCED GREEN FLUORESCENT PROTEIN; EPITOPE; FLUC REPLICASE; GLUC REPLICASE; MESSENGER RNA; NONSTRUCTURAL PROTEIN 1; NONSTRUCTURAL PROTEIN 2; NONSTRUCTURAL PROTEIN 3; NONSTRUCTURAL PROTEIN 4; RNA POLYMERASE; RNA POLYMERASE II; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS REPLICASE; BACTERIOPHAGE T7 RNA POLYMERASE; DNA DIRECTED RNA POLYMERASE; RNA DIRECTED RNA POLYMERASE; VIRAL PROTEIN; VIRUS RNA;

EID: 84962593335     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0151616     Document Type: Article
Times cited : (60)

References (69)
  • 1
    • 84930010146 scopus 로고    scopus 로고
    • Chikungunya: Evolutionary history and recent epidemic spread
    • 25979669
    • Weaver SC, Forrester NL. Chikungunya: Evolutionary history and recent epidemic spread. Antiviral Res. 2015;120:32-39. doi: 10.1016/j.antiviral.2015.04.016 PMID: 25979669
    • (2015) Antiviral Res. , vol.120 , pp. 32-39
    • Weaver, S.C.1    Forrester, N.L.2
  • 3
    • 84896884405 scopus 로고    scopus 로고
    • Functional cross-talk between distant domains of chikungunya virus nonstructural protein 2 is decisive for its RNA-modulating activity
    • 24407286
    • Das PK, Merits A, Lulla A. Functional cross-talk between distant domains of chikungunya virus nonstructural protein 2 is decisive for its RNA-modulating activity. J BiolChem. 2014;289:5635-5653. doi: 10.1074/jbc. M113.503433 PMID: 24407286
    • (2014) J BiolChem. , vol.289 , pp. 5635-5653
    • Das, P.K.1    Merits, A.2    Lulla, A.3
  • 4
    • 79960452364 scopus 로고    scopus 로고
    • NTPase and 5'-RNA triphosphatase activities of chikungunya virus nsP2 protein
    • 21811589
    • Karpe YA, Aher PP, Lole KS. NTPase and 5'-RNA Triphosphatase Activities of Chikungunya Virus nsP2 Protein. PLoS ONE. 2011;6:e22336. doi: 10.1371/journal.pone.0022336 PMID: 21811589
    • (2011) PLoS ONE , vol.6 , pp. e22336
    • Karpe, Y.A.1    Aher, P.P.2    Lole, K.S.3
  • 5
    • 67449102614 scopus 로고    scopus 로고
    • The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket
    • 19386706
    • Malet H, Coutard B, Jamal S, Dutartre H, Papageorgiou N, Neuvonen M, et al. The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket. J Virol. 2009;83:6534-6545. doi: 10.1128/JVI.00189-09 PMID: 19386706
    • (2009) J Virol. , vol.83 , pp. 6534-6545
    • Malet, H.1    Coutard, B.2    Jamal, S.3    Dutartre, H.4    Papageorgiou, N.5    Neuvonen, M.6
  • 6
    • 84923166545 scopus 로고    scopus 로고
    • Mutations conferring a noncytotoxic phenotype on chikungunya virus replicons compromise enzymatic properties of nonstructural protein 2
    • 25552719
    • Utt A, Das PK, Varjak M, Lulla V, Lulla A, Merits A. Mutations conferring a noncytotoxic phenotype on chikungunya virus replicons compromise enzymatic properties of nonstructural protein 2. J Virol. 2015;89:3145-3162. doi: 10.1128/JVI.03213-14 PMID: 25552719
    • (2015) J Virol. , vol.89 , pp. 3145-3162
    • Utt, A.1    Das, P.K.2    Varjak, M.3    Lulla, V.4    Lulla, A.5    Merits, A.6
  • 7
    • 84871196139 scopus 로고    scopus 로고
    • Sequestration of G3BP coupled with efficient translation inhibits stress granules in Semliki Forest virus infection
    • 23087212
    • Panas MD, Varjak M, Lulla A, Eng KE, Merits A, Karlsson Hedestam GB, et al. Sequestration of G3BP coupled with efficient translation inhibits stress granules in Semliki Forest virus infection. Mol Biol Cell. 2012;23:4701-4712. doi: 10.1091/mbc. E12-08-0619 PMID: 23087212
    • (2012) Mol Biol Cell. , vol.23 , pp. 4701-4712
    • Panas, M.D.1    Varjak, M.2    Lulla, A.3    Eng, K.E.4    Merits, A.5    Karlsson Hedestam, G.B.6
  • 8
    • 84925386816 scopus 로고    scopus 로고
    • Stress granule components G3BP1 and G3BP2 play aproviral role early in Chikungunya virus replication
    • 25653451
    • Scholte F E M, Tas A, Albulescu IC, Žusinaite E, Merits A, Snijder EJ, et al. Stress granule components G3BP1 and G3BP2 play aproviral role early in Chikungunya virus replication. J Virol. 2015;89:4457-4469. doi: 10.1128/JVI.03612-14 PMID: 25653451
    • (2015) J Virol. , vol.89 , pp. 4457-4469
    • Scholte, F.E.M.1    Tas, A.2    Albulescu, I.C.3    Žusinaite, E.4    Merits, A.5    Snijder, E.J.6
  • 9
    • 84869049624 scopus 로고    scopus 로고
    • Chikungunya virus nsP3 blocks stress granule assembly by recruitment of G3BP into cytoplasmic foci
    • 22837213
    • Fros JJ, Domeradzka NE, Baggen J, Geertsema C, Flipse J, Vlak JM, et al. Chikungunya virus nsP3 blocks stress granule assembly by recruitment of G3BP into cytoplasmic foci. J Virol. 2012;86:10873-10879. doi: 10.1128/JVI.01506-12 PMID: 22837213
    • (2012) J Virol. , vol.86 , pp. 10873-10879
    • Fros, J.J.1    Domeradzka, N.E.2    Baggen, J.3    Geertsema, C.4    Flipse, J.5    Vlak, J.M.6
  • 10
    • 84945959691 scopus 로고    scopus 로고
    • Differential Phosphatidylinositol-3-Kinase-Akt-mTOR Activation by Semliki Forest and Chikungunya Viruses is Dependent on nsP3 and Connected to Replication Complex Internalization
    • 26339054
    • Thaa B, Biasiotto R, Eng K, Neuvonen M, Götte B, Rheinemann L, et al. Differential Phosphatidylinositol-3-Kinase-Akt-mTOR Activation by Semliki Forest and Chikungunya Viruses Is Dependent on nsP3 and Connected to Replication Complex Internalization. J Virol. 2015;89:11420-11437. doi: 10.1128/JVI.01579-15 PMID: 26339054
    • (2015) J Virol. , vol.89 , pp. 11420-11437
    • Thaa, B.1    Biasiotto, R.2    Eng, K.3    Neuvonen, M.4    Götte, B.5    Rheinemann, L.6
  • 11
    • 84872791019 scopus 로고    scopus 로고
    • Differential unfolded protein response during Chikungunya and Sindbis virus infection: CHIKVnsP4 suppresses eIF2a phosphorylation
    • 23356742
    • Rathore A P S, Ng M-L, Vasudevan SG. Differential unfolded protein response during Chikungunya and Sindbis virus infection: CHIKVnsP4 suppresses eIF2a phosphorylation. Virol J. 2013;10:36. doi: 10. 1186/1743-422X-10-36 PMID: 23356742
    • (2013) Virol J. , vol.10 , pp. 36
    • Rathore, A.P.S.1    Ng, M.-L.2    Vasudevan, S.G.3
  • 12
    • 0035175362 scopus 로고    scopus 로고
    • Cis-acting RNA elements at the 5' end of Sindbis virus genome RNA regulate minus- and plus-strand RNA synthesis
    • Frolov I, Hardy R, Rice CM. Cis-acting RNA elements at the 5' end of Sindbis virus genome RNA regulate minus- and plus-strand RNA synthesis. RNA NY N. 2001;7:1638-1651.
    • (2001) RNA NY N. , vol.7 , pp. 1638-1651
    • Frolov, I.1    Hardy, R.2    Rice, C.M.3
  • 13
    • 16244413640 scopus 로고    scopus 로고
    • Requirements atthe3' end of the sindbis virus genome for efficient synthesis of minus-strand RNA
    • 15795249
    • Hardy RW, Rice CM. Requirements atthe3' end of the sindbis virus genome for efficient synthesis of minus-strand RNA. J Virol. 2005;79:4630-4639. doi: 10.1128/JVI.79.8.4630-4639.2005 PMID: 15795249
    • (2005) J Virol. , vol.79 , pp. 4630-4639
    • Hardy, R.W.1    Rice, C.M.2
  • 14
    • 0025213983 scopus 로고
    • Promoter for Sindbis virus RNA-dependentsubgenomic RNA transcription
    • 2319651
    • Levis R, Schlesinger S, Huang HV. Promoter for Sindbis virus RNA-dependentsubgenomic RNA transcription. J Virol. 1990;64:1726-1733. PMID: 2319651
    • (1990) J Virol. , vol.64 , pp. 1726-1733
    • Levis, R.1    Schlesinger, S.2    Huang, H.V.3
  • 15
    • 0028088152 scopus 로고
    • The alphaviruses: Gene expression, replication, and evolution
    • 7968923
    • Strauss JH, Strauss EG. The alphaviruses: gene expression, replication, and evolution. Microbiol Rev. 1994;58:491-562. PMID: 7968923
    • (1994) Microbiol Rev. , vol.58 , pp. 491-562
    • Strauss, J.H.1    Strauss, E.G.2
  • 16
    • 0027475009 scopus 로고
    • Roles of nonstructural polyproteins and cleavage products in regulating Sindbis virus RNA replication and transcription
    • 8445717
    • Lemm JA, Rice CM. Roles of nonstructural polyproteins and cleavage products in regulating Sindbis virus RNA replication and transcription. J Virol. 1993;67:1916-1926. PMID: 8445717
    • (1993) J Virol. , vol.67 , pp. 1916-1926
    • Lemm, J.A.1    Rice, C.M.2
  • 17
    • 0037301423 scopus 로고    scopus 로고
    • Properly folded nonstructural polyprotein directs the semliki forest virus replication complex to the endosomal compartment
    • 12525603
    • Salonen A, Vasiljeva L, Merits A, Magden J, Jokitalo E, Kääriäinen L. Properly folded nonstructural polyprotein directs the semliki forest virus replication complex to the endosomal compartment. J Virol. 2003;77:1691-1702. PMID: 12525603
    • (2003) J Virol. , vol.77 , pp. 1691-1702
    • Salonen, A.1    Vasiljeva, L.2    Merits, A.3    Magden, J.4    Jokitalo, E.5    Kääriäinen, L.6
  • 18
    • 0028221438 scopus 로고
    • Polypeptide requirements for assembly of functional Sindbis virus replication complexes: A model forthe temporal regulation of minus- and plusstrand RNA synthesis
    • 7517863
    • Lemm JA, Rumenapf T, Strauss EG, Strauss JH, Rice CM. Polypeptide requirements for assembly of functional Sindbis virus replication complexes: a model forthe temporal regulation of minus- and plusstrand RNA synthesis. EMBO J. 1994;13:2925-2934. PMID: 7517863
    • (1994) EMBO J. , vol.13 , pp. 2925-2934
    • Lemm, J.A.1    Rumenapf, T.2    Strauss, E.G.3    Strauss, J.H.4    Rice, C.M.5
  • 19
    • 84958087646 scopus 로고    scopus 로고
    • RNA replication and membrane modification require the same functions of alphavirus nonstructural proteins
    • Kallio K, Hellström K, Jokitalo E, Ahola T. RNA replication and membrane modification require the same functions of alphavirus nonstructural proteins. J Virol. 2015; doi: 10.1128/JVI.02484-15
    • (2015) J Virol.
    • Kallio, K.1    Hellström, K.2    Jokitalo, E.3    Ahola, T.4
  • 20
    • 77954505687 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase-, actin-, and microtubuledependent transport of Semliki Forest Virus replication complexes from the plasma membrane to modified lysosomes
    • 20484502
    • Spuul P, Balistreri G, Kääriäinen L, Ahola T. Phosphatidylinositol 3-kinase-, actin-, and microtubuledependent transport of Semliki Forest Virus replication complexes from the plasma membrane to modified lysosomes. J Virol. 2010;84:7543-7557. doi: 10.1128/JVI.00477-10 PMID: 20484502
    • (2010) J Virol. , vol.84 , pp. 7543-7557
    • Spuul, P.1    Balistreri, G.2    Kääriäinen, L.3    Ahola, T.4
  • 21
    • 84926610921 scopus 로고    scopus 로고
    • Sequence analysis reveals a conserved extension in the capping enzyme of the alphavirus supergroup, and a homologous domain in nodaviruses
    • 25886938
    • Ahola T, Karlin DG. Sequence analysis reveals a conserved extension in the capping enzyme of the alphavirus supergroup, and a homologous domain in nodaviruses. Biol Direct. 2015;10:16. doi: 10. 1186/s13062-015-0050-0 PMID: 25886938
    • (2015) Biol Direct. , vol.10 , pp. 16
    • Ahola, T.1    Karlin, D.G.2
  • 22
    • 58549095054 scopus 로고    scopus 로고
    • Characterization of purified Sindbis virus nsP4 RNA-dependent RNA polymerase activity in vitro
    • 19036396
    • Rubach JK, Wasik BR, Rupp JC, Kuhn RJ, Hardy RW, Smith JL. Characterization of purified Sindbis virus nsP4 RNA-dependent RNA polymerase activity in vitro. Virology. 2009;384:201-208. doi: 10. 1016/j.virol.2008.10.030 PMID: 19036396
    • (2009) Virology. , vol.384 , pp. 201-208
    • Rubach, J.K.1    Wasik, B.R.2    Rupp, J.C.3    Kuhn, R.J.4    Hardy, R.W.5    Smith, J.L.6
  • 23
    • 84875253993 scopus 로고    scopus 로고
    • BST-2/tetherin-mediated restriction of chikungunya (CHIKV) VLP budding is counteracted by CHIKV non-structural protein 1 (nsP1)
    • 23411007
    • Jones PH, Maric M, Madison MN, Maury W, Roller RJ, Okeoma CM. BST-2/tetherin-mediated restriction of chikungunya (CHIKV) VLP budding is counteracted by CHIKV non-structural protein 1 (nsP1). Virology. 2013;438:37-49. doi: 10.1016/j.virol.2013.01.010 PMID: 23411007
    • (2013) Virology , vol.438 , pp. 37-49
    • Jones, P.H.1    Maric, M.2    Madison, M.N.3    Maury, W.4    Roller, R.J.5    Okeoma, C.M.6
  • 24
    • 77957192174 scopus 로고    scopus 로고
    • Chikungunya virus nonstructural protein 2 inhibits type I/II interferon-stimulated JAK-STAT signaling
    • 20686047
    • Fros JJ, Liu WJ, Prow NA, Geertsema C, Ligtenberg M, Vanlandingham DL, et al. Chikungunya virus nonstructural protein 2 inhibits type I/II interferon-stimulated JAK-STAT signaling. J Virol. 2010;84:10877-10887. doi: 10.1128/JVI.00949-10 PMID: 20686047
    • (2010) J Virol. , vol.84 , pp. 10877-10887
    • Fros, J.J.1    Liu, W.J.2    Prow, N.A.3    Geertsema, C.4    Ligtenberg, M.5    Vanlandingham, D.L.6
  • 25
    • 84883261933 scopus 로고    scopus 로고
    • The C-terminal domain of chikungunya virus nsP2 independently governs viral RNA replication, cytopathicity, and inhibition of interferon signaling
    • 23864632
    • Fros JJ, van der Maten E, Vlak JM, Pijlman GP. The C-terminal domain of chikungunya virus nsP2 independently governs viral RNA replication, cytopathicity, and inhibition of interferon signaling. J Virol. 2013;87:10394-10400. doi: 10.1128/JVI.00884-13 PMID: 23864632
    • (2013) J Virol. , vol.87 , pp. 10394-10400
    • Fros, J.J.1    Van Der Maten, E.2    Vlak, J.M.3    Pijlman, G.P.4
  • 26
    • 84923677240 scopus 로고    scopus 로고
    • Chikungunya virus nonstructural protein 2-mediated host shut-off disables the unfolded protein response
    • 25395592
    • Fros JJ, Major LD, Scholte F E M, Gardner J, van Hemert MJ, Suhrbier A, et al. Chikungunya virus nonstructural protein 2-mediated host shut-off disables the unfolded protein response. J Gen Virol. 2015;96:580-589. doi: 10.1099/vir.0.071845-0 PMID: 25395592
    • (2015) J Gen Virol. , vol.96 , pp. 580-589
    • Fros, J.J.1    Major, L.D.2    Scholte, F.E.M.3    Gardner, J.4    Van Hemert, M.J.5    Suhrbier, A.6
  • 27
    • 22544443363 scopus 로고    scopus 로고
    • Inhibition of transcription and translation in Sindbis virus-infected cells
    • 16014903
    • Gorchakov R, Frolova E, Frolov I. Inhibition of transcription and translation in Sindbis virus-infected cells. J Virol. 2005;79:9397-9409. doi: 10.1128/JVI.79.15.9397-9409.2005 PMID: 16014903
    • (2005) J Virol. , vol.79 , pp. 9397-9409
    • Gorchakov, R.1    Frolova, E.2    Frolov, I.3
  • 28
    • 84864122222 scopus 로고    scopus 로고
    • Evasion of the innate immune response: The Old World alphavirus nsP2 protein induces rapid degradation of Rpb1, a catalytic subunit of RNA polymerase II
    • 22514352
    • Akhrymuk I, Kulemzin SV, Frolova EI. Evasion of the innate immune response: the Old World alphavirus nsP2 protein induces rapid degradation of Rpb1, a catalytic subunit of RNA polymerase II. J Virol. 2012;86:7180-7191. doi: 10.1128/JVI.00541-12 PMID: 22514352
    • (2012) J Virol. , vol.86 , pp. 7180-7191
    • Akhrymuk, I.1    Kulemzin, S.V.2    Frolova, E.I.3
  • 29
    • 84924405914 scopus 로고    scopus 로고
    • Viral and cellular proteins containing FGDF motifs bind G3BP to block stress granule formation
    • 25658430
    • Panas MD, Schulte T, Thaa B, Sandalova T, Kedersha N, Achour A, et al. Viral and cellular proteins containing FGDF motifs bind G3BP to block stress granule formation. PLoS Pathog. 2015;11:e1004659. doi: 10.1371/journal.ppat.1004659 PMID: 25658430
    • (2015) PLoS Pathog. , vol.11 , pp. e1004659
    • Panas, M.D.1    Schulte, T.2    Thaa, B.3    Sandalova, T.4    Kedersha, N.5    Achour, A.6
  • 30
    • 81755182978 scopus 로고    scopus 로고
    • SH3 domain-mediated recruitment of host cell amphiphysins by alphavirus nsP3 promotes viral RNA replication
    • 22114558
    • Neuvonen M, Kazlauskas A, Martikainen M, Hinkkanen A, Ahola T, Saksela K. SH3 domain-mediated recruitment of host cell amphiphysins by alphavirus nsP3 promotes viral RNA replication. PLoS Pathog. 2011;7:e1002383. doi: 10.1371/journal.ppat.1002383 PMID: 22114558
    • (2011) PLoS Pathog. , vol.7 , pp. e1002383
    • Neuvonen, M.1    Kazlauskas, A.2    Martikainen, M.3    Hinkkanen, A.4    Ahola, T.5    Saksela, K.6
  • 31
    • 84855936001 scopus 로고    scopus 로고
    • Macromolecular assembly-driven processing of the 2/3 cleavage site in the alphavirus replicase polyprotein
    • 22031949
    • Lulla A, Lulla V, Merits A. Macromolecular Assembly-Driven Processing of the 2/3 Cleavage Site in the Alphavirus Replicase Polyprotein. J Virol. 2012;86:553-565. doi: 10.1128/JVI.05195-11 PMID: 22031949
    • (2012) J Virol. , vol.86 , pp. 553-565
    • Lulla, A.1    Lulla, V.2    Merits, A.3
  • 32
    • 0031937629 scopus 로고    scopus 로고
    • Requirement for an aromatic amino acid or histidineatthe N terminus of Sindbis virus RNA polymerase
    • 9499091
    • Shirako Y, Strauss JH. Requirement for an aromatic amino acid or histidineatthe N terminus of Sindbis virus RNA polymerase. J Virol. 1998;72:2310-2315. PMID: 9499091
    • (1998) J Virol. , vol.72 , pp. 2310-2315
    • Shirako, Y.1    Strauss, J.H.2
  • 33
    • 77649206548 scopus 로고    scopus 로고
    • Novel functions of the alphavirus nonstructural protein nsP3 C-terminal region
    • 20015978
    • Varjak M, Zusinaite E, Merits A. Novel functions of the alphavirus nonstructural protein nsP3 C-terminal region. J Virol. 2010;84:2352-2364. doi: 10.1128/JVI.01540-09 PMID: 20015978
    • (2010) J Virol. , vol.84 , pp. 2352-2364
    • Varjak, M.1    Zusinaite, E.2    Merits, A.3
  • 34
    • 0142060863 scopus 로고    scopus 로고
    • Expression of the Zinc-Finger Antiviral Protein Inhibits Alphavirus Replication
    • 14557641
    • Bick MJ, Carroll J-WN, Gao G, Goff SP, Rice CM, MacDonald MR. Expression of the Zinc-Finger Antiviral Protein Inhibits Alphavirus Replication. J Virol. 2003;77:11555-11562. doi: 10.1128/JVI.77.21. 11555-11562.2003 PMID: 14557641
    • (2003) J Virol. , vol.77 , pp. 11555-11562
    • Bick, M.J.1    Carroll, J.-W.N.2    Gao, G.3    Goff, S.P.4    Rice, C.M.5    MacDonald, M.R.6
  • 35
    • 79952415597 scopus 로고    scopus 로고
    • Antiviral RNA interference responses induced by Semliki Forest virus infection of mosquito cells: Characterization, origin, and frequency-dependent functions of virus-derived small interfering RNAs
    • 21191029
    • Siu R W C, Fragkoudis R, Simmonds P, Donald CL, Chase-Topping ME, Barry G, et al. Antiviral RNA interference responses induced by Semliki Forest virus infection of mosquito cells: characterization, origin, and frequency-dependent functions of virus-derived small interfering RNAs. J Virol. 2011;85:2907-2917. doi: 10.1128/JVI.02052-10 PMID: 21191029
    • (2011) J Virol. , vol.85 , pp. 2907-2917
    • Siu, R.W.C.1    Fragkoudis, R.2    Simmonds, P.3    Donald, C.L.4    Chase-Topping, M.E.5    Barry, G.6
  • 36
    • 33645779746 scopus 로고    scopus 로고
    • Formation of nsP3-specific protein complexes during Sindbis virus replication
    • 16571828
    • Frolova E, Gorchakov R, Garmashova N, Atasheva S, Vergara LA, Frolov I. Formation of nsP3-specific protein complexes during Sindbis virus replication. J Virol. 2006;80:4122-4134. doi: 10.1128/JVI.80.8. 4122-4134.2006 PMID: 16571828
    • (2006) J Virol. , vol.80 , pp. 4122-4134
    • Frolova, E.1    Gorchakov, R.2    Garmashova, N.3    Atasheva, S.4    Vergara, L.A.5    Frolov, I.6
  • 37
    • 34248359925 scopus 로고    scopus 로고
    • Development of Sindbis viruses encoding nsP2/GFP chimeric proteins and their application for studying nsP2 functioning
    • 17329335
    • Atasheva S, Gorchakov R, English R, Frolov I, Frolova E. Development of Sindbis viruses encoding nsP2/GFP chimeric proteins and their application for studying nsP2 functioning. J Virol. 2007;81:5046-5057. doi: 10.1128/JVI.02746-06 PMID: 17329335
    • (2007) J Virol. , vol.81 , pp. 5046-5057
    • Atasheva, S.1    Gorchakov, R.2    English, R.3    Frolov, I.4    Frolova, E.5
  • 38
    • 77953320616 scopus 로고    scopus 로고
    • Host factors associated with the Sindbis virus RNA-dependent RNA polymerase: Role for G3BP1 and G3BP2 in virus replication
    • 20392851
    • Cristea IM, Rozjabek H, Molloy KR, Karki S, White LL, Rice CM, et al. Host factors associated with the Sindbis virus RNA-dependent RNA polymerase: role for G3BP1 and G3BP2 in virus replication. J Virol. 2010;84:6720-6732. doi: 10.1128/JVI.01983-09 PMID: 20392851
    • (2010) J Virol. , vol.84 , pp. 6720-6732
    • Cristea, I.M.1    Rozjabek, H.2    Molloy, K.R.3    Karki, S.4    White, L.L.5    Rice, C.M.6
  • 39
    • 84883309644 scopus 로고    scopus 로고
    • Presentation overrides specificity: Probing the plasticity of alphaviral proteolytic activity through mutational analysis
    • 23864614
    • Lulla V, Karo-Astover L, Rausalu K, Merits A, Lulla A. Presentation Overrides Specificity: Probing the Plasticity of Alphaviral Proteolytic Activity through Mutational Analysis. J Virol. 2013;87:10207-10220. doi: 10.1128/JVI.01485-13 PMID: 23864614
    • (2013) J Virol. , vol.87 , pp. 10207-10220
    • Lulla, V.1    Karo-Astover, L.2    Rausalu, K.3    Merits, A.4    Lulla, A.5
  • 40
    • 33846052318 scopus 로고    scopus 로고
    • Role of the amphipathic peptide of Semliki forest virus replicase protein nsP1 in membrane association and virus replication
    • 17093195
    • Spuul P, Salonen A, Merits A, Jokitalo E, Kääriäinen L, Ahola T. Role of the amphipathic peptide of Semliki forest virus replicase protein nsP1 in membrane association and virus replication. J Virol. 2007;81:872-883. doi: 10.1128/JVI.01785-06 PMID: 17093195
    • (2007) J Virol. , vol.81 , pp. 872-883
    • Spuul, P.1    Salonen, A.2    Merits, A.3    Jokitalo, E.4    Kääriäinen, L.5    Ahola, T.6
  • 41
    • 34347366405 scopus 로고    scopus 로고
    • Mutations at the palmitoylation site of non-structural protein nsP1 of Semliki Forest virus attenuate virus replication and cause accumulation of compensatory mutations
    • 17554031
    • Zusinaite E, Tints K, Kiiver K, Spuul P, Karo-Astover L, Merits A, et al. Mutations at the palmitoylation site of non-structural protein nsP1 of Semliki Forest virus attenuate virus replication and cause accumulation of compensatory mutations. J Gen Virol. 2007;88:1977-1985. doi: 10.1099/vir.0.82865-0 PMID: 17554031
    • (2007) J Gen Virol. , vol.88 , pp. 1977-1985
    • Zusinaite, E.1    Tints, K.2    Kiiver, K.3    Spuul, P.4    Karo-Astover, L.5    Merits, A.6
  • 42
    • 0022498060 scopus 로고
    • Deletion mapping of Sindbis virus DI RNAs derived from cDNAs defines the sequences essential for replication and packaging
    • 3753584
    • Levis R, Weiss BG, Tsiang M, Huang H, Schlesinger S. Deletion mapping of Sindbis virus DI RNAs derived from cDNAs defines the sequences essential for replication and packaging. Cell. 1986;44:137-145. PMID: 3753584
    • (1986) Cell , vol.44 , pp. 137-145
    • Levis, R.1    Weiss, B.G.2    Tsiang, M.3    Huang, H.4    Schlesinger, S.5
  • 43
    • 14744304517 scopus 로고
    • A new generation of animal cell expression vectors based on the Semliki Forest virus replicon
    • Liljeström P, Garoff H. A new generation of animal cell expression vectors based on the Semliki Forest virus replicon. Biotechnol Nat Publ Co. 1991;9:1356-1361.
    • (1991) Biotechnol Nat Publ Co , vol.9 , pp. 1356-1361
    • Liljeström, P.1    Garoff, H.2
  • 44
    • 78049491884 scopus 로고    scopus 로고
    • Functional Sindbis virus replicative complexes are formed at the plasma membrane
    • 20826696
    • Frolova EI, Gorchakov R, Pereboeva L, Atasheva S, Frolov I. Functional Sindbis virus replicative complexes are formed at the plasma membrane. J Virol. 2010;84:11679-11695. doi: 10.1128/JVI.01441-10 PMID: 20826696
    • (2010) J Virol. , vol.84 , pp. 11679-11695
    • Frolova, E.I.1    Gorchakov, R.2    Pereboeva, L.3    Atasheva, S.4    Frolov, I.5
  • 45
    • 79955426289 scopus 로고    scopus 로고
    • Assembly of alphavirus replication complexes from RNA and protein components in a novel trans-replication system in mammalian cells
    • 21389137
    • Spuul P, Balistreri G, Hellström K, Golubtsov AV, Jokitalo E, Ahola T. Assembly of alphavirus replication complexes from RNA and protein components in a novel trans-replication system in mammalian cells. J Virol. 2011;85:4739-4751. doi: 10.1128/JVI.00085-11 PMID: 21389137
    • (2011) J Virol. , vol.85 , pp. 4739-4751
    • Spuul, P.1    Balistreri, G.2    Hellström, K.3    Golubtsov, A.V.4    Jokitalo, E.5    Ahola, T.6
  • 46
    • 84881231721 scopus 로고    scopus 로고
    • Template RNA length determines the size of replication complex spherules for Semliki Forest virus
    • 23760239
    • Kallio K, Hellström K, Balistreri G, Spuul P, Jokitalo E, Ahola T. Template RNA length determines the size of replication complex spherules for Semliki Forest virus. J Virol. 2013;87:9125-9134. doi: 10. 1128/JVI.00660-13 PMID: 23760239
    • (2013) J Virol. , vol.87 , pp. 9125-9134
    • Kallio, K.1    Hellström, K.2    Balistreri, G.3    Spuul, P.4    Jokitalo, E.5    Ahola, T.6
  • 47
    • 84884689115 scopus 로고    scopus 로고
    • RIG-I and MDA-5 detection of viral RNA-dependent RNA polymerase activity restricts positive-strand RNA virus replication
    • 24039580
    • Nikonov A, Mölder T, Sikut R, Kiiver K, Männik A, Toots U, et al. RIG-I and MDA-5 detection of viral RNA-dependent RNA polymerase activity restricts positive-strand RNA virus replication. PLoS Pathog. 2013;9:e1003610. doi: 10.1371/journal.ppat.1003610 PMID: 24039580
    • (2013) PLoS Pathog. , vol.9 , pp. e1003610
    • Nikonov, A.1    Mölder, T.2    Sikut, R.3    Kiiver, K.4    Männik, A.5    Toots, U.6
  • 48
    • 0032708941 scopus 로고    scopus 로고
    • Efficient trans-complementation of the flavivirus kunjin NS5 protein but not of the NS1 protein requires its coexpression with other components of the viral replicase
    • 10559344
    • Khromykh AA, Sedlak PL, Guyatt KJ, Hall RA, Westaway EG. Efficient trans-complementation of the flavivirus kunjin NS5 protein but not of the NS1 protein requires its coexpression with other components of the viral replicase. J Virol. 1999;73:10272-10280. PMID: 10559344
    • (1999) J Virol. , vol.73 , pp. 10272-10280
    • Khromykh, A.A.1    Sedlak, P.L.2    Guyatt, K.J.3    Hall, R.A.4    Westaway, E.G.5
  • 49
    • 0031870247 scopus 로고    scopus 로고
    • Trans-Complementation of flavivirus RNA polymerase gene NS5 by using Kunjin virus replicon-expressing BHK cells
    • 9696822
    • Khromykh AA, Kenney MT, Westaway EG. trans-Complementation of flavivirus RNA polymerase gene NS5 by using Kunjin virus replicon-expressing BHK cells. J Virol. 1998;72:7270-7279. PMID: 9696822
    • (1998) J Virol. , vol.72 , pp. 7270-7279
    • Khromykh, A.A.1    Kenney, M.T.2    Westaway, E.G.3
  • 50
    • 0032888955 scopus 로고    scopus 로고
    • Generation of bovine respiratory syncytial virus (BRSV) from cDNA: BRSV NS2 is not essential for virus replication in tissue culture, and the human RSV leader region acts as a functional BRSV genome promoter
    • 9847328
    • Buchholz UJ, Finke S, Conzelmann K-K. Generation of Bovine Respiratory Syncytial Virus (BRSV) from cDNA: BRSV NS2 Is Not Essential for Virus Replication in Tissue Culture, and the Human RSV Leader Region Acts as a Functional BRSV Genome Promoter. J Virol. 1999;73:251-259. PMID: 9847328
    • (1999) J Virol. , vol.73 , pp. 251-259
    • Buchholz, U.J.1    Finke, S.2    Conzelmann, K.-K.3
  • 51
    • 0019863480 scopus 로고
    • A region of the polyoma virus genome between the replication origin and late protein coding sequences is required in cis for both early gene expression and viral DNA replication
    • 6275353
    • Tyndall C, La Mantia G, Thacker CM, Favaloro J, Kamen R. A region of the polyoma virus genome between the replication origin and late protein coding sequences is required in cis for both early gene expression and viral DNA replication. Nucleic Acids Res. 1981;9:6231-6250. PMID: 6275353
    • (1981) Nucleic Acids Res. , vol.9 , pp. 6231-6250
    • Tyndall, C.1    La Mantia, G.2    Thacker, C.M.3    Favaloro, J.4    Kamen, R.5
  • 52
    • 34047240645 scopus 로고    scopus 로고
    • Translational efficiency of EMCV IRES in bicistronic vectors is dependent upon IRES sequence and gene location
    • 16989088 286, 288 passim
    • Bochkov YA, Palmenberg AC. Translational efficiency of EMCV IRES in bicistronic vectors is dependent upon IRES sequence and gene location. BioTechniques. 2006;41:283-284, 286, 288 passim. PMID: 16989088
    • (2006) BioTechniques , vol.41 , pp. 283-284
    • Bochkov, Y.A.1    Palmenberg, A.C.2
  • 53
    • 78650028269 scopus 로고    scopus 로고
    • A robust system for production of minicircle DNA vectors
    • 21102455
    • Kay MA, He C-Y, Chen Z-Y. A robust system for production of minicircle DNA vectors. Nat Biotechnol. 2010;28:1287-1289. doi: 10.1038/nbt.1708 PMID: 21102455
    • (2010) Nat Biotechnol. , vol.28 , pp. 1287-1289
    • Kay, M.A.1    He, C.-Y.2    Chen, Z.-Y.3
  • 54
    • 84880115054 scopus 로고    scopus 로고
    • Virus replicon particle based Chikungunya virus neutralization assay using Gaussia luciferase as readout
    • 23855906
    • Gläsker S, Lulla A, Lulla V, Couderc T, Drexler JF, Liljeström P, et al. Virus replicon particle based Chikungunya virus neutralization assay using Gaussia luciferase as readout. Virol J. 2013;10:235. doi: 10.1186/1743-422X-10-235 PMID: 23855906
    • (2013) Virol J. , vol.10 , pp. 235
    • Gläsker, S.1    Lulla, A.2    Lulla, V.3    Couderc, T.4    Drexler, J.F.5    Liljeström, P.6
  • 56
    • 0041315884 scopus 로고    scopus 로고
    • Minicircle DNA vectors devoid of bacterial DNA result in persistent and high-level transgene expression in vivo
    • Chen Z-Y, He C-Y, Ehrhardt A, Kay MA. Minicircle DNA vectors devoid of bacterial DNA result in persistent and high-level transgene expression in vivo. MolTherJ AmSocGeneTher. 2003;8:495-500.
    • (2003) MolTherJ AmSocGeneTher. , vol.8 , pp. 495-500
    • Chen, Z.-Y.1    He, C.-Y.2    Ehrhardt, A.3    Kay, M.A.4
  • 57
    • 84871919467 scopus 로고    scopus 로고
    • Minicircle DNA vectors achieve sustained expression reflected by active chromatin and transcriptional level
    • Gracey Maniar LE, Maniar JM, Chen Z-Y, Lu J, Fire AZ, Kay MA. Minicircle DNA vectors achieve sustained expression reflected by active chromatin and transcriptional level. Mol Ther J Am Soc Gene Ther. 2013;21:131-138. doi: 10.1038/mt.2012.244
    • (2013) Mol Ther J Am Soc Gene Ther. , vol.21 , pp. 131-138
    • Gracey Maniar, L.E.1    Maniar, J.M.2    Chen, Z.-Y.3    Lu, J.4    Fire, A.Z.5    Kay, M.A.6
  • 59
    • 84893508642 scopus 로고    scopus 로고
    • Stable, high-level expression of reporter proteins from improved alphavirus expression vectors to track replication and dissemination during encephaliticand arthritogenic disease
    • 24307590
    • Sun C, Gardner CL, Watson AM, Ryman KD, Klimstra WB. Stable, high-level expression of reporter proteins from improved alphavirus expression vectors to track replication and dissemination during encephaliticand arthritogenic disease. J Virol. 2014;88:2035-2046. doi: 10.1128/JVI.02990-13 PMID: 24307590
    • (2014) J Virol. , vol.88 , pp. 2035-2046
    • Sun, C.1    Gardner, C.L.2    Watson, A.M.3    Ryman, K.D.4    Klimstra, W.B.5
  • 60
    • 84905457299 scopus 로고    scopus 로고
    • Characterization of Aedes aegypti innate-immune pathways that limit Chikungunya virus replication
    • 25058001
    • McFarlane M, Arias-Goeta C, Martin E, O'Hara Z, Lulla A, Mousson L, et al. Characterization of Aedes aegypti innate-immune pathways that limit Chikungunya virus replication. PLoS NeglTrop Dis. 2014;8:e2994. doi: 10.1371/journal.pntd.0002994 PMID: 25058001
    • (2014) PLoS NeglTrop Dis. , vol.8 , pp. e2994
    • McFarlane, M.1    Arias-Goeta, C.2    Martin, E.3    O'Hara, Z.4    Lulla, A.5    Mousson, L.6
  • 61
    • 0033814973 scopus 로고    scopus 로고
    • Replicon vectors derived from Sindbis virus and Semliki forest virus that establish persistent replication in host cells
    • 11000258
    • Perri S, Driver DA, Gardner JP, Sherrill S, Belli BA, Dubensky TW, et al. Replicon vectors derived from Sindbis virus and Semliki forest virus that establish persistent replication in host cells. J Virol. 2000;74:9802-9807. PMID: 11000258
    • (2000) J Virol. , vol.74 , pp. 9802-9807
    • Perri, S.1    Driver, D.A.2    Gardner, J.P.3    Sherrill, S.4    Belli, B.A.5    Dubensky, T.W.6
  • 62
    • 42449119438 scopus 로고    scopus 로고
    • Mutations in the nuclear localization signal of nsP2 influencing RNA synthesis, protein expression and cytotoxicity of Semliki Forest virus
    • 18272758
    • Tamm K, Merits A, Sarand I. Mutations in the nuclear localization signal of nsP2 influencing RNA synthesis, protein expression and cytotoxicity of Semliki Forest virus. J Gen Virol. 2008;89:676-686. doi: 10.1099/vir.0.83320-0 PMID: 18272758
    • (2008) J Gen Virol. , vol.89 , pp. 676-686
    • Tamm, K.1    Merits, A.2    Sarand, I.3
  • 63
    • 83655212354 scopus 로고    scopus 로고
    • Inhibitors of alphavirus entry and replication identified with a stable Chikungunya replicon cell line and virus-based assays
    • 22205980
    • Pohjala L, Utt A, Varjak M, Lulla A, Merits A, Ahola T, et al. Inhibitors of alphavirus entry and replication identified with a stable Chikungunya replicon cell line and virus-based assays. PloS One. 2011;6:e28923. doi: 10.1371/journal.pone.0028923 PMID: 22205980
    • (2011) PloS One , vol.6 , pp. e28923
    • Pohjala, L.1    Utt, A.2    Varjak, M.3    Lulla, A.4    Merits, A.5    Ahola, T.6
  • 64
    • 0030011522 scopus 로고    scopus 로고
    • Functional significance of the nuclear-targeting and NTP-binding motifs of Semliki Forest virus nonstructural protein nsP2
    • 8610462
    • Rikkonen M. Functional significance of the nuclear-targeting and NTP-binding motifs of Semliki Forest virus nonstructural protein nsP2. Virology. 1996;218:352-361. doi: 10.1006/viro.1996.0204 PMID: 8610462
    • (1996) Virology. , vol.218 , pp. 352-361
    • Rikkonen, M.1
  • 65
    • 0142211312 scopus 로고    scopus 로고
    • Regulation of the sequential processing of Semliki Forest virus replicase polyprotein
    • 12917405
    • Vasiljeva L, Merits A, Golubtsov A, Sizemskaja V, Kääriäinen L, Ahola T. Regulation of the sequential processing of Semliki Forest virus replicase polyprotein. J Biol Chem. 2003;278:41636-41645. doi: 10.1074/jbc. M307481200 PMID: 12917405
    • (2003) J Biol Chem. , vol.278 , pp. 41636-41645
    • Vasiljeva, L.1    Merits, A.2    Golubtsov, A.3    Sizemskaja, V.4    Kääriäinen, L.5    Ahola, T.6
  • 66
    • 69249209904 scopus 로고    scopus 로고
    • Fate of minus-strand templates and replication complexes produced by a P23-cleavage-defective mutant of sindbis virus
    • 19515769
    • Mai J, Sawicki SG, Sawicki DL. Fate of Minus-Strand Templates and Replication Complexes Produced by a P23-Cleavage-Defective Mutant of Sindbis Virus. J Virol. 2009;83:8553-8564. doi: 10.1128/JVI. 00056-09 PMID: 19515769
    • (2009) J Virol. , vol.83 , pp. 8553-8564
    • Mai, J.1    Sawicki, S.G.2    Sawicki, D.L.3
  • 67
    • 84893187370 scopus 로고    scopus 로고
    • Subgenomic reporter RNA system for detection of alphavirus infection in mosquitoes
    • 24367703
    • Steel JJ, Franz A W E, Sanchez-Vargas I, Olson KE, Geiss BJ. Subgenomic reporter RNA system for detection of alphavirus infection in mosquitoes. PloS One. 2013;8:e84930. doi: 10.1371/journal.pone. 0084930 PMID: 24367703
    • (2013) PloS One , vol.8 , pp. e84930
    • Steel, J.J.1    Franz, A.W.E.2    Sanchez-Vargas, I.3    Olson, K.E.4    Geiss, B.J.5
  • 68
    • 0025352629 scopus 로고
    • Cleavage-site preferences of Sindbis virus polyproteins containing the non-structural proteinase. Evidence for temporal regulation of polyprotein processing in vivo
    • 2142454
    • de Groot RJ, Hardy WR, Shirako Y, Strauss JH. Cleavage-site preferences of Sindbis virus polyproteins containing the non-structural proteinase. Evidence for temporal regulation of polyprotein processing in vivo. EMBO J. 1990;9:2631-2638. PMID: 2142454
    • (1990) EMBO J. , vol.9 , pp. 2631-2638
    • De Groot, R.J.1    Hardy, W.R.2    Shirako, Y.3    Strauss, J.H.4
  • 69
    • 84896703032 scopus 로고    scopus 로고
    • Novel attenuated chikungunya vaccine candidates elicit protective immunity in C57BL/6 mice
    • 24371047
    • Hallengärd D, Kakoulidou M, Lulla A, Kümmerer BM, Johansson DX, Mutso M, et al. Novel Attenuated Chikungunya Vaccine Candidates Elicit Protective Immunity in C57BL/6 mice. J Virol. 2014;88:2858-2866. doi: 10.1128/JVI.03453-13 PMID: 24371047
    • (2014) J Virol. , vol.88 , pp. 2858-2866
    • Hallengärd, D.1    Kakoulidou, M.2    Lulla, A.3    Kümmerer, B.M.4    Johansson, D.X.5    Mutso, M.6


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