SH3 domain-mediated recruitment of host cell amphiphysins by alphavirus nsp3 promotes viral RNA replication

PLoS Pathogens

Volumn 7, Issue 11, 2011, Pages

  Neuvonen, Maarit ^a   Kazlauskas, Arunas ^b   Martikainen, Miika ^c   Hinkkanen, Ari ^c   Ahola, Tero ^a   Saksela, Kalle ^b  

^a UNIVERSITY OF HELSINKI   (Finland)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^c UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHIPHYSIN; NONSTRUCTURAL PROTEIN 3; PROTEIN SH3; LIGAND; NERVE PROTEIN; NSP3 PROTEIN, VIRUS; VIRUS PROTEIN; VIRUS RNA;

ALPHA VIRUS; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING KINETICS; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CELLULAR DISTRIBUTION; CHIKUNGUNYA ALPHAVIRUS; CONTROLLED STUDY; FEMALE; HELA CELL; HOST CELL; HUMAN; HUMAN CELL; MORTALITY; NONHUMAN; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN MOTIF; RNA INTERFERENCE; RNA REPLICATION; SEMLIKI FOREST ALPHAVIRUS; SINDBIS VIRUS; VIRUS CELL INTERACTION; VIRUS REPLICATION; AMINO ACID SEQUENCE; ANIMAL; BIOSYNTHESIS; GENETICS; METABOLISM; MOUSE; SRC HOMOLOGY DOMAIN;

ALPHAVIRUS; CHIKUNGUNYA VIRUS; MUS; RABBIT FIBROMA VIRUS;

ALPHAVIRUS; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CHIKUNGUNYA VIRUS; HELA CELLS; HUMANS; LIGANDS; MICE; NERVE TISSUE PROTEINS; RNA, VIRAL; SEMLIKI FOREST VIRUS; SINDBIS VIRUS; SRC HOMOLOGY DOMAINS; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION;

EID: 81755182978     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002383     Document Type: Article

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