Virus replicon particle based Chikungunya virus neutralization assay using Gaussia luciferase as readout

Virology Journal

Volumn 10, Issue , 2013, Pages

  Gläsker, Sabine ^a   Lulla, Aleksei ^b   Lulla, Valeria ^b   Couderc, Therese ^c,d   Drexler, Jan Felix ^a   Liljeström, Peter ^e   Lecuit, Marc ^c,d,f   Drosten, Christian ^a   Merits, Andres ^b   Kümmerer, Beate Mareike ^a  

^a UNIVERSITY OF BONN   (Germany)

^b UNIVERSITY OF TARTU   (Estonia)

^c INSTITUT PASTEUR   (France)

^d INSERM   (France)

^e KAROLINSKA INSTITUTE   (Sweden)

^f IMAGINE INSTITUTE   (France)

Author keywords

Chikungunya virus; Gaussia luciferase; Neutralization assay; Virus replicon particles

Indexed keywords

CAPSID PROTEIN; LUCIFERASE; MONOCLONAL ANTIBODY; RNA; STRUCTURAL PROTEIN;

ANIMAL CELL; ARTICLE; ASSAY; CHIKUNGUNYA ALPHAVIRUS; CONTROLLED STUDY; HUMAN; INFECTION RATE; NONHUMAN; REPLICON; SERUM; SUPERNATANT; VIRUS INFECTION; VIRUS NEUTRALIZATION;

ANIMALS; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; CELL LINE; CHIKUNGUNYA VIRUS; CRICETINAE; GENES, REPORTER; HUMANS; LUCIFERASES; NEUTRALIZATION TESTS; TIME FACTORS;

CHIKUNGUNYA VIRUS; CRICETINAE; MIRIDAE;

EID: 84880115054     PISSN: None     EISSN: 1743422X     Source Type: Journal    
DOI: 10.1186/1743-422X-10-235     Document Type: Article

References (36)

1. Togaviridae: the viruses and their replicatioon. Kuhn RJ, Fields Virology Philadelphia: Lippincott Williams & Wilkons, Knipe DM, Howley PM, 5 2007 1 1001 1022
2. Alphavirus-based expression vectors: strategies and applications. Frolov I, Hoffman TA, Pragai BM, Dryga SA, Huang HV, Schlesinger S, Rice CM, Proc Natl Acad Sci USA 1996 93 11371 11377 10.1073/pnas.93.21.11371 8876142 (Pubitemid 26347128)
3. A new generation of animal cell expression vectors based on the Semliki Forest virus replicon. Liljeström P, Garoff H, Biotechnology (N Y) 1991 9 1356 1361 10.1038/nbt1291-1356
4. Replicon-helper systems from attenuated Venezuelan equine encephalitis virus: expression of heterologous genes in vitro and immunization against heterologous pathogens in vivo. Pushko P, Parker M, Ludwig GV, Davis NL, Johnston RE, Smith JF, Virology 1997 239 389 401 10.1006/viro.1997.8878 9434729 (Pubitemid 28105644)
5. Sindbis virus: an efficient, broad host range vector for gene expression in animal cells. Xiong C, Levis R, Shen P, Schlesinger S, Rice CM, Huang HV, Science 1989 243 1188 1191 10.1126/science.2922607 2922607
6. Two-helper RNA system for production of recombinant Semliki forest virus particles. Smerdou C, Liljeström P, J Virol 1999 73 1092 1098 9882310 (Pubitemid 29036760)
7. Sindbis virus replicons and Sindbis virus: assembly of chimeras and of particles deficient in virus RNA. Frolov I, Frolova E, Schlesinger S, J Virol 1997 71 2819 2829 9060637 (Pubitemid 27119921)
8. An epidemic of virus disease in Southern Province, Tanganyika Territory, in 1952-53. I. Clinical features. Robinson MC, Trans R Soc Trop Med Hyg 1955 49 28 32 10.1016/0035-9203(55)90080-8 14373834
9. The Newala epidemic. III. The virus: isolation, pathogenic properties and relationship to the epidemic. Ross RW, J Hyg (Lond) 1956 54 177 191 10.1017/S0022172400044442
10. Infectious diseases. Massive outbreak draws fresh attention to little-known virus. Enserink M, Science 2006 311 1085 16497896
11. Chikungunya outbreaks-the globalization of vectorborne diseases. Charrel RN, de Lamballerie X, Raoult D, N Engl J Med 2007 356 769 771 10.1056/NEJMp078013 17314335 (Pubitemid 46294608)
12. Sporadic cases of chikungunya, Reunion Island, August 2009. D'Ortenzio E, Grandadam M, Balleydier E, Dehecq JS, Jaffar-Bandjee MC, Michault A, Andriamandimby SF, Reynes JM, Filleul L, Euro Surveill 2009 14 35
13. A chikungunya outbreak associated with the vector Aedes albopictus in remote villages of Gabon. Paupy C, Kassa Kassa F, Caron M, Nkoghé D, Leroy EM, Vector Borne Zoonotic Dis 2012 12 167 169 10.1089/vbz.2011.0736 22141733
14. Epidemiology of Chikungunya infection on Reunion Island, Mayotte, and neighboring countries. Renault P, Balleydier E, D'Ortenzio E, Baville M, Filleul L, Med Mal Infect 2012 42 93 101 10.1016/j.medmal.2011.12.002 22280563
15. Infection with chikungunya virus in Italy: an outbreak in a temperate region. Rezza G, Nicoletti L, Angelini R, Romi R, Finarelli AC, Panning M, Cordioli P, Fortuna C, Boros S, Magurano F, Silvi G, Angelini P, Dottori M, Ciufolini MG, Majori GC, Cassone A, CHIKV study group, Lancet 2007 370 1840 1846 10.1016/S0140-6736(07)61779-6 18061059 (Pubitemid 350180033)
16. Chikungunya virus, southeastern France. Grandadam M, Caro V, Plumet S, Thiberge JM, Souares Y, Failloux AB, Tolou HJ, Budelot M, Cosserat D, Leparc-Goffart I, Despres P, Emerg Infect Dis 2011 17 910 913 10.3201/eid1705.101873 21529410
17. Vectors of Chikungunya virus in Senegal: current data and transmission cycles. Diallo M, Thonnon J, Traore-Lamizana M, Fontenille D, Am J Trop Med Hyg 1999 60 281 286 10072152 (Pubitemid 29107118)
18. Detection of Chikungunya virus in wild populations of Aedes albopictus in Kerala State, India. Kumar NP, Sabesan S, Krishnamoorthy K, Jambulingam P, Vector Borne Zoonotic Dis 2012 12 907 911 10.1089/vbz.2012.0969 22925018
19. A single mutation in chikungunya virus affects vector specificity and epidemic potential. Tsetsarkin KA, Vanlandingham DL, McGee CE, Higgs S, PLoS Pathog 2007 3 201 10.1371/journal.ppat.0030201 18069894
20. Outbreak of chikungunya on Reunion Island: early clinical and laboratory features in 157 adult patients. Borgherini G, Poubeau P, Staikowsky F, Lory M, Le Moullec N, Becquart JP, Wengling C, Michault A, Paganin F, Clin Infect Dis 2007 44 1401 1407 10.1086/517537 17479933 (Pubitemid 46801580)
21. Chikungunya virus infection. A retrospective study of 107 cases. Brighton SW, Prozesky OW, de la Harpe AL, S Afr Med J 1983 63 313 315 6298956 (Pubitemid 13121054)
22. Early appearance of neutralizing immunoglobulin G3 antibodies is associated with chikungunya virus clearance and long-term clinical protection. Kam YW, Simarmata D, Chow A, Her Z, Teng TS, Ong EK, Renia L, Leo YS, Ng LF, J Infect Dis 2012 205 1147 1154 10.1093/infdis/jis033 22389226
23. Evaluation of recombinant E2 protein-based and whole-virus inactivated candidate vaccines against chikungunya virus. Kumar M, Sudeep AB, Arankalle VA, Vaccine 2012 30 6142 6149 10.1016/j.vaccine.2012.07.072 22884660
24. Early neutralizing IgG response to Chikungunya virus in infected patients targets a dominant linear epitope on the E2 glycoprotein. Kam YW, Lum FM, Teo TH, Lee WW, Simarmata D, Harjanto S, Chua CL, Chan YF, Wee JK, Chow A, Lin RT, Leo YS, Le Grand R, Sam IC, Tong JC, Roques P, Wiesmüller KH, Rénia L, Rötzschke O, Ng LF, EMBO Mol Med 2012 4 330 343 10.1002/emmm.201200213 22389221
25. Subunit vaccine formulations based on recombinant envelope proteins of Chikungunya virus elicit balanced Th1/Th2 response and virus-neutralizing antibodies in mice. Khan M, Dhanwani R, Rao PV, Parida M, Virus Res 2012 167 236 246 10.1016/j.virusres.2012.05.004 22610133
26. Chimeric alphavirus vaccine candidates for chikungunya. Wang E, Volkova E, Adams AP, Forrester N, Xiao SY, Frolov I, Weaver SC, Vaccine 2008 26 5030 5039 10.1016/j.vaccine.2008.07.054 18692107
27. Development of a Pseudotyped Lentiviral Vector-Based Neutralization Assay for Chikungunya Virus Infection. Kishishita N, Takeda N, Anuegoonpipat A, Anantapreecha S, J Clin Microbiol 2013 51 1389 1395 10.1128/JCM.03109-12 23408687
28. Gaussia luciferase reporter assay for monitoring biological processes in culture and in vivo. Tannous BA, Nat Protoc 2009 4 582 591 10.1038/nprot.2009.28 19373229
29. Recombinant Gaussia luciferase. Overexpression, purification, and analytical application of a bioluminescent reporter for DNA hybridization. Verhaegent M, Christopoulos TK, Anal Chem 2002 74 4378 4385 10.1021/ac025742k 12236345 (Pubitemid 35006424)
30. Chikungunya fever in travelers returning to Europe from the Indian Ocean region, 2006. Panning M, Grywna K, van Esbroeck M, Emmerich P, Drosten C, Emerg Infect Dis 2008 14 416 422 10.3201/eid1403.070906 18325256 (Pubitemid 351451389)
31. Semliki Forest virus expression system: production of conditionally infectious recombinant particles. Berglund P, Sjoberg M, Garoff H, Atkins GJ, Sheahan BJ, Liljestrom P, Biotechnology (N Y) 1993 11 916 920 10.1038/nbt0893-916 (Pubitemid 23218980)
32. Translation of Sindbis virus mRNA: effects of sequences downstream of the initiating codon. Frolov I, Schlesinger S, J Virol 1994 68 8111 8117 7966601 (Pubitemid 24362700)
33. A significantly improved Semliki Forest virus expression system based on translation enhancer segments from the viral capsid gene. Sjöberg EM, Suomalainen M, Garoff H, Biotechnology (N Y) 1994 12 1127 1131 10.1038/nbt1194-1127
34. Codon-optimized Gaussia luciferase cDNA for mammalian gene expression in culture and in vivo. Tannous BA, Kim DE, Fernandez JL, Weissleder R, Breakefield XO, Mol Ther 2005 11 435 443 15727940 (Pubitemid 40277320)
35. A secreted luciferase for ex vivo monitoring of in vivo processes. Wurdinger T, Badr C, Pike L, de Kleine R, Weissleder R, Breakefield XO, Tannous BA, Nat Methods 2008 5 171 173 10.1038/nmeth.1177 18204457 (Pubitemid 351181745)
36. Inhibitors of alphavirus entry and replication identified with a stable Chikungunya replicon cell line and virus-based assays. Pohjala L, Utt A, Varjak M, Lulla A, Merits A, Ahola T, Tammela P, PLoS One 2011 6 28923 10.1371/journal.pone.0028923 22205980