Functional cross-talk between distant domains of chikungunya virus non-structural protein 2 is decisive for its RNA-modulating activity

Journal of Biological Chemistry

Volumn 289, Issue 9, 2014, Pages 5635-5653

  Das, Pratyush Kumar ^a   Merits, Andres ^a   Lulla, Aleksei ^a  

^a UNIVERSITY OF TARTU   (Estonia)

Author keywords

[No Author keywords available]

Indexed keywords

BIOINFORMATICS ANALYSIS; COMPARATIVE ANALYSIS; DOUBLE-STRANDED RNA; ENZYMATIC ACTIVITIES; HELICASE ACTIVITIES; MULTIFUNCTIONAL PROTEIN; PROTEASE ACTIVITIES; THERAPEUTIC INTERVENTION;

BIOINFORMATICS; PROTEINS; VIRUSES;

RNA;

DOUBLE STRANDED RNA; HELICASE; HYDROLASE; MAGNESIUM ION; NONSTRUCTURAL PROTEIN 2; PROTEIN NTPASE; RECOMBINANT ENZYME; RECOMBINANT PROTEIN; RNA; RNA HELICASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHIKUNGUNYA ALPHAVIRUS; CONTROLLED STUDY; GENETIC REGULATION; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; RNA BINDING; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; WILD TYPE;

ALPHAVIRUS; CHIKUNGUNYA VIRUS; ENZYMES; NTPASE; POSITIVE-STRAND RNA VIRUSES; PROTEIN PURIFICATION; RNA ANNEALING; RNA HELICASE; SF1 HELICASE; VIRAL REPLICATION;

ALPHAVIRUS INFECTIONS; CHIKUNGUNYA VIRUS; NUCLEOSIDE-TRIPHOSPHATASE; PROTEIN STRUCTURE, TERTIARY; RNA HELICASES; RNA, DOUBLE-STRANDED; RNA, VIRAL; VIRAL NONSTRUCTURAL PROTEINS;

EID: 84896884405     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.503433     Document Type: Article

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