-
2
-
-
33645907197
-
B cell lineages: Documented at last! Nat
-
Herzenberg, L. A., and J. W. Tung. 2006. B cell lineages: documented at last! Nat. Immunol. 7:225-226.
-
(2006)
Immunol.
, vol.7
, pp. 225-226
-
-
Herzenberg, L.A.1
Tung, J.W.2
-
3
-
-
0036569215
-
Cutting edge commentary: Two B-1 or not to be one
-
Rothstein, T. L. 2002. Cutting edge commentary: two B-1 or not to be one. J. Immunol. 168:4257-4261.
-
(2002)
J. Immunol.
, vol.168
, pp. 4257-4261
-
-
Rothstein, T.L.1
-
5
-
-
68749088267
-
Continual signaling is responsible for constitutive ERK phosphorylation in B-1α cells
-
Holodick, N. E., J. R. Tumang, and T. L. Rothstein. 2009. Continual signaling is responsible for constitutive ERK phosphorylation in B-1α cells. Mol. Immunol. 46:3029-3036.
-
(2009)
Mol. Immunol.
, vol.46
, pp. 3029-3036
-
-
Holodick, N.E.1
Tumang, J.R.2
Rothstein, T.L.3
-
6
-
-
0030946515
-
Signal transducer and activator of transcription-3 (STAT3) is constitutively activated in normal, self-renewing B-1 cells but only inducibly expressed in conventional B lymphocytes
-
Karras, J. G., Z. Wang, L. Huo, R. G. Howard, D. A. Frank, and T. L. Rothstein. 1997. Signal transducer and activator of transcription-3 (STAT3) is constitutively activated in normal, self-renewing B-1 cells but only inducibly expressed in conventional B lymphocytes. J. Exp. Med. 185:1035-1042.
-
(1997)
J. Exp. Med.
, vol.185
, pp. 1035-1042
-
-
Karras, J.G.1
Wang, Z.2
Huo, L.3
Howard, R.G.4
Frank, D.A.5
Rothstein, T.L.6
-
7
-
-
0027453153
-
Abnormal transcription factor induction through the surface immunoglobulin M receptor of B-1 lymphocytes
-
Morris, D. L., and T. L. Rothstein. 1993. Abnormal transcription factor induction through the surface immunoglobulin M receptor of B-1 lymphocytes. J. Exp. Med. 177:857-861.
-
(1993)
J. Exp. Med.
, vol.177
, pp. 857-861
-
-
Morris, D.L.1
Rothstein, T.L.2
-
8
-
-
0033515101
-
Innate and acquired humoral immunities to influenza virus are mediated by distinct arms of the immune system
-
Baumgarth, N., O. C. Herman, G. C. Jager, L. Brown, L. A. Herzenberg, and L. A. Herzenberg. 1999. Innate and acquired humoral immunities to influenza virus are mediated by distinct arms of the immune system. Proc. Natl. Acad. Sci. USA 96:2250-2255.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 2250-2255
-
-
Baumgarth, N.1
Herman, O.C.2
Jager, G.C.3
Brown, L.4
Herzenberg, L.A.5
Herzenberg, L.A.6
-
9
-
-
73249130668
-
A novel subpopulation of B-1 cells is enriched with autoreactivity in normal and lupus-prone mice
-
Zhong, X., S. Lau, C. Bai, N. Degauque, N. E. Holodick, S. J. Steven, J. Tumang, W. Gao, and T. L. Rothstein. 2009. A novel subpopulation of B-1 cells is enriched with autoreactivity in normal and lupus-prone mice. Arthritis Rheum. 60:3734-3743.
-
(2009)
Arthritis Rheum.
, vol.60
, pp. 3734-3743
-
-
Zhong, X.1
Lau, S.2
Bai, C.3
Degauque, N.4
Holodick, N.E.5
Steven, S.J.6
Tumang, J.7
Gao, W.8
Rothstein, T.L.9
-
11
-
-
22544470027
-
B-1α and B-1β cells exhibit distinct developmental requirements and have unique functional roles in innate and adaptive immunity to S
-
Haas, K. M., J. C. Poe, D. A. Steeber, and T. F. Tedder. 2005. B-1α and B-1β cells exhibit distinct developmental requirements and have unique functional roles in innate and adaptive immunity to S. pneumoniae. Immunity 23:7-18.
-
(2005)
Pneumoniae. Immunity
, vol.23
, pp. 7-18
-
-
Haas, K.M.1
Poe, J.C.2
Steeber, D.A.3
Tedder, T.F.4
-
12
-
-
0034679710
-
B-1 and B-2 cell-derived immunoglobulin M antibodies are nonredundant components of the protective response to influenza virus infection
-
Baumgarth, N., O. C. Herman, G. C. Jager, L. E. Brown, L. A. Herzenberg, and J. Chen. 2000. B-1 and B-2 cell-derived immunoglobulin M antibodies are nonredundant components of the protective response to influenza virus infection. J. Exp. Med. 192:271-280.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 271-280
-
-
Baumgarth, N.1
Herman, O.C.2
Jager, G.C.3
Brown, L.E.4
Herzenberg, L.A.5
Chen, J.6
-
13
-
-
78049313303
-
The importance of natural IgM: Scavenger, protector and regulator
-
Ehrenstein, M. R., and C. A. Notley. 2010. The importance of natural IgM: scavenger, protector and regulator. Nat. Rev. Immunol. 10:778-786.
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 778-786
-
-
Ehrenstein, M.R.1
Notley, C.A.2
-
14
-
-
79953715358
-
Regulatory natural autoantibodies to apoptotic cells: Pallbearers and protectors
-
Silverman, G. J. 2011. Regulatory natural autoantibodies to apoptotic cells: pallbearers and protectors. Arthritis Rheum. 63:597-602.
-
(2011)
Arthritis Rheum.
, vol.63
, pp. 597-602
-
-
Silverman, G.J.1
-
15
-
-
0032524389
-
RasGRP, a Ras guanyl nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs
-
Ebinu, J. O., D. A. Bottorff, E. Y. Chan, S. L. Stang, R. J. Dunn, and J. C. Stone. 1998. RasGRP, a Ras guanyl nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs. Science 280:1082-1086.
-
(1998)
Science
, vol.280
, pp. 1082-1086
-
-
Ebinu, J.O.1
Bottorff, D.A.2
Chan, E.Y.3
Stang, S.L.4
Dunn, R.J.5
Stone, J.C.6
-
16
-
-
2542444383
-
Diacylglycerol-dependent binding recruits PKCu and RasGRP1 C1 domains to specific subcellular localizations in living T lymphocytes
-
Carrasco, S., and I. Merida. 2004. Diacylglycerol-dependent binding recruits PKCu and RasGRP1 C1 domains to specific subcellular localizations in living T lymphocytes. Mol. Biol. Cell 15:2932-2942.
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 2932-2942
-
-
Carrasco, S.1
Merida, I.2
-
17
-
-
34547739994
-
Regulation of RasGRP1 by B cell antigen receptor requires cooperativity between three domains controlling translocation to the plasma membrane
-
Beaulieu, N., B. Zahedi, R. E. Goulding, G. Tazmini, K. V. Anthony, S. L. Omeis, D. R. De Jong, and R. J. Kay. 2007. Regulation of RasGRP1 by B cell antigen receptor requires cooperativity between three domains controlling translocation to the plasma membrane. Mol. Biol. Cell 18:3156-3168.
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 3156-3168
-
-
Beaulieu, N.1
Zahedi, B.2
Goulding, R.E.3
Tazmini, G.4
Anthony, K.V.5
Omeis, S.L.6
De Jong, D.R.7
Kay, R.J.8
-
18
-
-
28244476478
-
RasGRP1 and RasGRP3 regulate B cell proliferation by facilitating B cell receptor-Ras signaling
-
Coughlin, J. J., S. L. Stang, N. A. Dower, and J. C. Stone. 2005. RasGRP1 and RasGRP3 regulate B cell proliferation by facilitating B cell receptor-Ras signaling. J. Immunol. 175:7179-7184.
-
(2005)
J. Immunol.
, vol.175
, pp. 7179-7184
-
-
Coughlin, J.J.1
Stang, S.L.2
Dower, N.A.3
Stone, J.C.4
-
19
-
-
0034303371
-
RasGRP is essential for mouse thymocyte differentiation and TCR signaling
-
Dower, N. A., S. L. Stang, D. A. Bottorff, J. O. Ebinu, P. Dickie, H. L. Ostergaard, and J. C. Stone. 2000. RasGRP is essential for mouse thymocyte differentiation and TCR signaling. Nat. Immunol. 1:317-321.
-
(2000)
Nat. Immunol.
, vol.1
, pp. 317-321
-
-
Dower, N.A.1
Stang, S.L.2
Bottorff, D.A.3
Ebinu, J.O.4
Dickie, P.5
Ostergaard, H.L.6
Stone, J.C.7
-
20
-
-
33846435302
-
An essential role for RasGRP1 in mast cell function and IgE-mediated allergic response
-
Liu, Y., M. Zhu, K. Nishida, T. Hirano, and W. Zhang. 2007. An essential role for RasGRP1 in mast cell function and IgE-mediated allergic response. J. Exp. Med. 204:93-103.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 93-103
-
-
Liu, Y.1
Zhu, M.2
Nishida, K.3
Hirano, T.4
Zhang, W.5
-
21
-
-
80555133366
-
Critical roles of RasGRP1 for invariant NKT cell development
-
Shen, S., Y. Chen, B. K. Gorentla, J. Lu, J. C. Stone, and X. P. Zhong. 2011. Critical roles of RasGRP1 for invariant NKT cell development. J. Immunol. 187:4467-4473.
-
(2011)
J. Immunol.
, vol.187
, pp. 4467-4473
-
-
Shen, S.1
Chen, Y.2
Gorentla, B.K.3
Lu, J.4
Stone, J.C.5
Zhong, X.P.6
-
22
-
-
0036848708
-
RasGRP1 transduces low-grade TCR signals which are critical for T cell development, homeostasis, and differentiation
-
Priatel, J. J., S. J. Teh, N. A. Dower, J. C. Stone, and H. S. Teh. 2002. RasGRP1 transduces low-grade TCR signals which are critical for T cell development, homeostasis, and differentiation. Immunity 17:617-627.
-
(2002)
Immunity
, vol.17
, pp. 617-627
-
-
Priatel, J.J.1
Teh, S.J.2
Dower, N.A.3
Stone, J.C.4
Teh, H.S.5
-
23
-
-
0023749983
-
+ (CD5) B cells that recognize phosphatidyl choline. Relationship to cells that secrete hemolytic antibody specific for autologous erythrocytes
-
+ (CD5) B cells that recognize phosphatidyl choline. Relationship to cells that secrete hemolytic antibody specific for autologous erythrocytes. J. Exp. Med. 168:687-698.
-
(1988)
J. Exp. Med.
, vol.168
, pp. 687-698
-
-
Mercolino, T.J.1
Arnold, L.W.2
Hawkins, L.A.3
Haughton, G.4
-
24
-
-
0344823990
-
Normal B-1α cell development requires B cell-intrinsic NFATc1 activity
-
Berland, R., and H. H. Wortis. 2003. Normal B-1α cell development requires B cell-intrinsic NFATc1 activity. Proc. Natl. Acad. Sci. USA 100:13459-13464.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 13459-13464
-
-
Berland, R.1
Wortis, H.H.2
-
25
-
-
79955731369
-
NFATc1 affects mouse splenic B cell function by controlling the calcineurin-NFAT signaling network
-
Bhattacharyya, S., J. Deb, A. K. Patra, D. A. Thuy Pham, W. Chen, M. Vaeth, F. Berberich-Siebelt, S. Klein-Hessling, E. D. Lamperti, K. Reifenberg, et al. 2011. NFATc1 affects mouse splenic B cell function by controlling the calcineurin-NFAT signaling network. J. Exp. Med. 208:823-839.
-
(2011)
J. Exp. Med.
, vol.208
, pp. 823-839
-
-
Bhattacharyya, S.1
Deb, J.2
Patra, A.K.3
Thuy Pham, D.A.4
Chen, W.5
Vaeth, M.6
Berberich-Siebelt, F.7
Klein-Hessling, S.8
Lamperti, E.D.9
Reifenberg, K.10
-
26
-
-
0025369696
-
Elevated expression of Pgp-1 (Ly-24) by murine peritoneal B lymphocytes
-
Murphy, T. P., D. L. Kolber, and T. L. Rothstein. 1990. Elevated expression of Pgp-1 (Ly-24) by murine peritoneal B lymphocytes. Eur. J. Immunol. 20:1137-1142.
-
(1990)
Eur. J. Immunol.
, vol.20
, pp. 1137-1142
-
-
Murphy, T.P.1
Kolber, D.L.2
Rothstein, T.L.3
-
27
-
-
4444384574
-
Peritoneal and splenic B-1 cells are separable by phenotypic, functional, and transcriptomic characteristics
-
Tumang, J. R., W. D. Hastings, C. Bai, and T. L. Rothstein. 2004. Peritoneal and splenic B-1 cells are separable by phenotypic, functional, and transcriptomic characteristics. Eur. J. Immunol. 34:2158-2167.
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 2158-2167
-
-
Tumang, J.R.1
Hastings, W.D.2
Bai, C.3
Rothstein, T.L.4
-
28
-
-
41549103208
-
Erk kinases link pre-B cell receptor signaling to transcriptional events required for early B cell expansion
-
Yasuda, T., H. Sanjo, G. Pagès, Y. Kawano, H. Karasuyama, J. Pouysségur, M. Ogata, and T. Kurosaki. 2008. Erk kinases link pre-B cell receptor signaling to transcriptional events required for early B cell expansion. Immunity 28:499-508.
-
(2008)
Immunity
, vol.28
, pp. 499-508
-
-
Yasuda, T.1
Sanjo, H.2
Pagès, G.3
Kawano, Y.4
Karasuyama, H.5
Pouysségur, J.6
Ogata, M.7
Kurosaki, T.8
-
29
-
-
33646587068
-
Phenotypically distinct B cell development pathways map to the three B cell lineages in the mouse
-
Tung, J. W., M. D. Mrazek, Y. Yang, L. A. Herzenberg, and L. A. Herzenberg. 2006. Phenotypically distinct B cell development pathways map to the three B cell lineages in the mouse. Proc. Natl. Acad. Sci. USA 103:6293-6298.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 6293-6298
-
-
Tung, J.W.1
Mrazek, M.D.2
Yang, Y.3
Herzenberg, L.A.4
Herzenberg, L.A.5
-
31
-
-
78650600361
-
The double life of a B-1 cell: Self-reactivity selects for protective effector functions
-
Baumgarth, N. 2011. The double life of a B-1 cell: self-reactivity selects for protective effector functions. Nat. Rev. Immunol. 11:34-46.
-
(2011)
Nat. Rev. Immunol.
, vol.11
, pp. 34-46
-
-
Baumgarth, N.1
-
32
-
-
33751262186
-
Regulation of Ras in lymphocytes: Get a GRP
-
Stone, J. C. 2006. Regulation of Ras in lymphocytes: get a GRP. Biochem. Soc. Trans. 34:858-861.
-
(2006)
Biochem. Soc. Trans.
, vol.34
, pp. 858-861
-
-
Stone, J.C.1
-
33
-
-
0036884819
-
Regulation of B-cell fate by antigen-receptor signals
-
Niiro, H., and E. A. Clark. 2002. Regulation of B-cell fate by antigen-receptor signals. Nat. Rev. Immunol. 2:945-956.
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 945-956
-
-
Niiro, H.1
Clark, E.A.2
-
34
-
-
0025948793
-
Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens
-
Hartley, S. B., J. Crosbie, R. Brink, A. B. Kantor, A. Basten, and C. C. Goodnow. 1991. Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens. Nature 353:765-769.
-
(1991)
Nature
, vol.353
, pp. 765-769
-
-
Hartley, S.B.1
Crosbie, J.2
Brink, R.3
Kantor, A.B.4
Basten, A.5
Goodnow, C.C.6
-
35
-
-
0033516689
-
Positive selection of natural autoreactive B cells
-
Hayakawa, K., M. Asano, S. A. Shinton, M. Gui, D. Allman, C. L. Stewart, J. Silver, and R. R. Hardy. 1999. Positive selection of natural autoreactive B cells. Science 285:113-116.
-
(1999)
Science
, vol.285
, pp. 113-116
-
-
Hayakawa, K.1
Asano, M.2
Shinton, S.A.3
Gui, M.4
Allman, D.5
Stewart, C.L.6
Silver, J.7
Hardy, R.R.8
-
36
-
-
0035229933
-
Disruption of T cell signaling networks and development by Grb2 haploid insufficiency
-
Gong, Q., A. M. Cheng, A. M. Akk, J. Alberola-Ila, G. Gong, T. Pawson, and A. C. Chan. 2001. Disruption of T cell signaling networks and development by Grb2 haploid insufficiency. Nat. Immunol. 2:29-36.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 29-36
-
-
Gong, Q.1
Cheng, A.M.2
Akk, A.M.3
Alberola-Ila, J.4
Gong, G.5
Pawson, T.6
Chan, A.C.7
-
37
-
-
17144458301
-
Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice
-
Pagès, G., S. Guérin, D. Grall, F. Bonino, A. Smith, F. Anjuere, P. Auberger, and J. Pouysségur. 1999. Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice. Science 286:1374-1377.
-
(1999)
Science
, vol.286
, pp. 1374-1377
-
-
Pagès, G.1
Guérin, S.2
Grall, D.3
Bonino, F.4
Smith, A.5
Anjuere, F.6
Auberger, P.7
Pouysségur, J.8
-
38
-
-
0028859281
-
Selective requirement for MAP kinase activation in thymocyte differentiation
-
Alberola-Ila, J., K. A. Forbush, R. Seger, E. G. Krebs, and R. M. Perlmutter. 1995. Selective requirement for MAP kinase activation in thymocyte differentiation. Nature 373:620-623.
-
(1995)
Nature
, vol.373
, pp. 620-623
-
-
Alberola-Ila, J.1
Forbush, K.A.2
Seger, R.3
Krebs, E.G.4
Perlmutter, R.M.5
-
39
-
-
0032191837
-
Differential roles of ERK and p38 MAP kinase pathways in positive and negative selection of T lymphocytes
-
Sugawara, T., T. Moriguchi, E. Nishida, and Y. Takahama. 1998. Differential roles of ERK and p38 MAP kinase pathways in positive and negative selection of T lymphocytes. Immunity 9:565-574.
-
(1998)
Immunity
, vol.9
, pp. 565-574
-
-
Sugawara, T.1
Moriguchi, T.2
Nishida, E.3
Takahama, Y.4
-
40
-
-
0032509479
-
Defective T cell differentiation in the absence of Jnk1
-
Dong, C., D. D. Yang, M. Wysk, A. J. Whitmarsh, R. J. Davis, and R. A. Flavell. 1998. Defective T cell differentiation in the absence of Jnk1. Science 282:2092-2095.
-
(1998)
Science
, vol.282
, pp. 2092-2095
-
-
Dong, C.1
Yang, D.D.2
Wysk, M.3
Whitmarsh, A.J.4
Davis, R.J.5
Flavell, R.A.6
-
41
-
-
84862231986
-
Regulation of RasGRP1 function in T cell development and activation by its unique tail domain
-
Fuller, D. M., M. Zhu, X. Song, C. W. Ou-Yang, S. A. Sullivan, J. C. Stone, and W. Zhang. 2012. Regulation of RasGRP1 function in T cell development and activation by its unique tail domain. PLoS One 7:e38796.
-
(2012)
PLoS One
, vol.7
, pp. e38796
-
-
Fuller, D.M.1
Zhu, M.2
Song, X.3
Ou-Yang, C.W.4
Sullivan, S.A.5
Stone, J.C.6
Zhang, W.7
-
42
-
-
84890412893
-
+ T cells and autoantibodies
-
+ T cells and autoantibodies. eLife 2:e01020.
-
(2013)
ELife
, vol.2
, pp. e01020
-
-
Daley, S.R.1
Coakley, K.M.2
Hu, D.Y.3
Randall, K.L.4
Jenne, C.N.5
Limnander, A.6
Myers, D.R.7
Polakos, N.K.8
Enders, A.9
Roots, C.10
-
43
-
-
39749157996
-
Defective expression of Ras guanyl nucleotide-releasing protein 1 in a subset of patients with systemic lupus erythematosus
-
Yasuda, S., R. L. Stevens, T. Terada, M. Takeda, T. Hashimoto, J. Fukae, T. Horita, H. Kataoka, T. Atsumi, and T. Koike. 2007. Defective expression of Ras guanyl nucleotide-releasing protein 1 in a subset of patients with systemic lupus erythematosus. J. Immunol. 179:4890-4900.
-
(2007)
J. Immunol.
, vol.179
, pp. 4890-4900
-
-
Yasuda, S.1
Stevens, R.L.2
Terada, T.3
Takeda, M.4
Hashimoto, T.5
Fukae, J.6
Horita, T.7
Kataoka, H.8
Atsumi, T.9
Koike, T.10
-
44
-
-
82955207664
-
Constitutive abnormal expression of RasGRP-1 isoforms and low expression of PARP-1 in patients with systemic lupus erythematosus
-
Rapoport, M. J., O. Bloch, M. Amit-Vasina, E. Yona, and Y. Molad. 2011. Constitutive abnormal expression of RasGRP-1 isoforms and low expression of PARP-1 in patients with systemic lupus erythematosus. Lupus 20:1501-1509.
-
(2011)
Lupus
, vol.20
, pp. 1501-1509
-
-
Rapoport, M.J.1
Bloch, O.2
Amit-Vasina, M.3
Yona, E.4
Molad, Y.5
-
45
-
-
34848882195
-
Chronic immunodeficiency in mice lacking RasGRP1 results in CD4 T cell immune activation and exhaustion
-
Priatel, J. J., X. Chen, L. A. Zenewicz, H. Shen, K. W. Harder, M. S. Horwitz, and H. S. Teh. 2007. Chronic immunodeficiency in mice lacking RasGRP1 results in CD4 T cell immune activation and exhaustion. J. Immunol. 179:2143-2152.
-
(2007)
J. Immunol.
, vol.179
, pp. 2143-2152
-
-
Priatel, J.J.1
Chen, X.2
Zenewicz, L.A.3
Shen, H.4
Harder, K.W.5
Horwitz, M.S.6
Teh, H.S.7
-
46
-
-
33746189876
-
Autoimmunity during lymphopenia: A two-hit model
-
Krupica, T., Jr., T. J. Fry, and C. L. Mackall. 2006. Autoimmunity during lymphopenia: a two-hit model. Clin. Immunol. 120:121-128.
-
(2006)
Clin. Immunol.
, vol.120
, pp. 121-128
-
-
Krupica, T.1
Fry, T.J.2
Mackall, C.L.3
-
47
-
-
84885149922
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Multiple checkpoint breach of B cell tolerance in Rasgrp1-deficient mice
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Bartlett, A., J. E. Buhlmann, J. Stone, B. Lim, and R. A. Barrington. 2013. Multiple checkpoint breach of B cell tolerance in Rasgrp1-deficient mice. J. Immunol. 191:3605-3613.
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(2013)
J. Immunol.
, vol.191
, pp. 3605-3613
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Bartlett, A.1
Buhlmann, J.E.2
Stone, J.3
Lim, B.4
Barrington, R.A.5
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