Peritoneal and splenic B-1 cells are separable by phenotypic, functional, and transcriptomic characteristics

European Journal of Immunology

Volumn 34, Issue 8, 2004, Pages 2158-2167

  Tumang, Joseph R ^a   Hastings, William D ^a   Bai, Chunyan ^a   Rothstein, Thomas L ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

B lymphocytes; Cell surface molecules; Cellular differentiation; Cellular proliferation; Gene regulation

Indexed keywords

B7 ANTIGEN; IMMUNOGLOBULIN M; MEMBRANE ANTIGEN; NOTCH RECEPTOR;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; B 1 LYMPHOCYTE; B LYMPHOCYTE; CELL CYCLE; CELL ISOLATION; CELL SELECTION; CELL SURVIVAL; CELL VIABILITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EX VIVO STUDY; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GENETIC TRANSCRIPTION; IMMUNOGLOBULIN PRODUCTION; IN VITRO STUDY; LYMPHOCYTE FUNCTION; LYMPHOCYTE SUBPOPULATION; MALE; MOUSE; NONHUMAN; PERITONEUM CELL; PHENOTYPIC VARIATION; PRIORITY JOURNAL; SPLEEN CELL; VALIDATION PROCESS; ANIMAL; CLASSIFICATION; GENE EXPRESSION; IMMUNOLOGY; PERITONEUM; PHYSIOLOGY; SPLEEN;

ANIMALS; ANTIGENS, CD80; B-LYMPHOCYTE SUBSETS; FLOW CYTOMETRY; GENE EXPRESSION; GENE EXPRESSION PROFILING; IMMUNOGLOBULIN M; MALE; MICE; PERITONEUM; SPLEEN;

EID: 4444384574     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200424819     Document Type: Article

References (49)

1. Herzenberg, L. A., B-1 cells: the lineage question revisited. Immunol. Rev. 2000. 175: 9-22.
2. Wortis, H. H. and Berland, R., Cutting edge commentary: origins of B-1 cells. J. Immunol. 2001. 166: 2163-2166.
3. Rothstein, T. L., Cutting edge commentary: two B-1 or not to be one. J. Immunol. 2002. 168: 4257-4261.
4. Hayakawa, K., Hardy, R. R. and Herzenberg, L. A., Progenitors for Ly-1 B cells are distinct from progenitors for other B cells. J Exp Med 1985. 161: 1554-1568.
5. Hayakawa, K., Hardy, R. R., Stall, A. M. and Herzenberg, L. A., Immunoglobulin-bearing B cells reconstitute and maintain the murine Ly-1 B cell lineage. Eur. J. Immunol. 1986. 16: 1313-1316.
6. Solvason, N., Lehuen, A. and Kearney, J. F., An embryonic source of Ly1 but not conventional B cells. Int. Immunol. 1991. 3: 543-550.
7. Hardy, R. R. and Hayakawa, K., A developmental switch in B lymphopoiesis. Proc. Natl. Acad. Sci. USA 1991. 88: 11550-11554.
8. Kantor, A. B., Stall, A. M., Adams, S. and Herzenberg, L. A., Differential development of progenitor activity for three B-cell lineages. Proc. Natl. Acad. Sci. USA 1992. 89: 3320-3324.
9. Godin, I. E., Garcia-Porrero, J. A., Coutinho, A., Dieterlen-Lievre, F. and Marcos, M. A., Para-aortic splanchnopleura from early mouse embryos contains B1a cell progenitors. Nature 1993. 364: 67-70.
10. - B cells with anti-Ig, but not LPS, induces surface CD5: two B-cell activation pathways. Int. Immunol. 1991. 3: 467-476.
11. Arnold, L. W., Pennell, C. A., McCray, S. K. and Clarke, S. H., Development of B-1 cells: segregation of phosphatidyl choline-specific B cells to the B-1 population occurs after immunoglobulin gene expression. J. Exp. Med. 1994. 179: 1585-1595.
12. Chumley, M. J., Dal Porto, J. M., Kawaguchi, S., Cambier, J. C., Nemazee, D. and Hardy, R. R., A VH11V kappa 9 B cell antigen receptor drives generation of CD5+ B cells both in vivo and in vitro. J. Immunol. 2000. 164: 4586-4593.
13. Hayakawa, K., Asano, M., Shinton, S. A., Gui, M., Allman, D., Stewart, C. L., Silver, J. and Hardy, R. R., Positive selection of natural autoreactive B cells. Science 1999. 285: 113-116.
14. Fruman, D. A., Satterthwaite, A. B. and Witte, O. N., Xid-like phenotypes: a B cell signalosome takes shape. Immunity 2000. 13: 1-3.
15. Wells, S. M., Kantor, A. B. and Stall, A. M., CD43 (S7) expression identifies peripheral B cell subsets. J. Immunol. 1994. 153: 5503-5515.
16. Ansel, K. M., Harris, R. B. and Cyster, J. G., CXCL13 is required for B1 cell homing, natural antibody production, and body cavity immunity. Immunity 2002. 16: 67-76.
17. Ohdan, H., Swenson, K. G., Kruger Gray, H. S., Yang, Y. G., Xu, Y., Thall, A. D. and Sykes, M., Mac-1-negative B-1 b phenotype of natural antibody-producing cells, including those responding to Gal alpha 1,3Gal epitopes in alpha 1,3-galactosyltransferase-deficient mice. J. Immunol. 2000. 165: 5518-5529.
18. Fischer, G. M., Solt, L. A., Yang, K., Gerstein, R. M., Nikolajczyk, B. S., Clarke, S. H. and Rothstein, T. L., Splenic and peritoneal B-1 cells are distinct populations as defined by transcriptional and proliferative features that separate peritoneal B-1 from splenic B-2 cells. Cell. Immunol. 2001. 213: 62-71.
19. Hippen, K. L., Tze, L. E. and Behrens, T. W., CD5 maintains tolerance in anergic B cells. J. Exp. Med. 2000. 191: 883-890.
20. + B cells: the Ly-1 B lineage? Annu. Rev. Immunol. 1988. 6: 197-218.
21. + B cells upon transfer of peritoneal cells into allotypecongenic, newborn mice. Eur. J. Immunol. 1987. 17: 521-528.
22. Ishida, H., Hastings, R., Kearney, J. and Howard, M., Continuous anti-interleukin 10 antibody administration depletes mice of Ly-1 B cells but not conventional B cells. J. Exp. Med. 1992. 175: 1213-1220.
23. Rothstein, T. L. and Kolber, D. L., Peritoneal B cells respond to phorbol esters in the absence of co- mitogen. J. Immunol. 1988. 140: 2880-2885.
24. Morris, D. L. and Rothstein, T. L., Abnormal transcription factor induction through the surface immunoglobulin M receptor of B-1 lymphocytes. J. Exp. Med. 1993. 177: 857-861.
25. Morris, D. L. and Rothstein, T. L., Analysis of B-1 cell activation. Methods: A companion to Methods Enzymol. 1995. 8: 11-25.
26. He, Y. and Pear, W. S., Notch signalling in B cells. Semin. Cell. Dev. Biol. 2003. 14: 135-142.
27. Saito, T., Chiba, S., Ichikawa, M., Kunisato, A., Asai, T., Shimizu, K., Yamaguchi, T., Yamamoto, G., Seo, S., Kumano, K., Nakagami-Yamaguchi, E., Hamada, Y., Aizawa, S. and Hirai, H., Notch2 is preferentially expressed in mature B cells and indispensable for marginal zone B lineage development. Immunity 2003. 18: 675-685.
28. Kuroda, K., Han, H., Tani, S., Tanigaki, K., Tun, T., Furukawa, T., Taniguchi, Y., Kurooka, H., Hamada, Y., Toyokuni, S. and Honjo, T., Regulation of marginal zone B cell development by MINT, a suppressor of Notch/RBP-J signaling pathway. Immunity 2003. 18: 301-312.
29. Jarriault, S., Brou, C., Logeat, F., Schroeter, E. H., Kopan, R. and Israel, A., Signalling downstream of activated mammalian Notch. Nature 1995. 377: 355-358.
30. Oswald, F., Liptay, S., Adler, G. and Schmid, R. M., NF-kappaB2 is a putative target gene of activated Notch-1 via RBP-Jkappa. Mol. Cell Siol. 1998. 18: 2077-2088.
31. Jehn, B. M., Bielke, W., Pear, W. S. and Osborne, B. A., Cutting edge: protective effects of notch-1 on TCR-induced apoptosis. J. Immunol. 1999. 162: 635-638.
32. Barolo, S., Walker, R. G., Polyanovsky, A. D., Freschi, G., Keil, T. and Posakony, J. W., A notch-independent activity of suppressor of hairless is required for normal mechanoreceptor physiology. Cell 2000. 103: 957-969.
33. Chumley, M. J., Dal Porto, J. M. and Cambier, J. C., The unique antigen receptor signaling phenotype of B-1 cells is influenced by locale but induced by antigen. J. Immunol. 2002. 169: 1735-1743.
34. Kretschmer, K., Jungebloud, A., Stopkowicz, J., Stoermann, B., Hoffmann, R. and Weiss, S., Antibody repertoire and gene expression profile: implications for different developmental and functional traits of splenic and peritoneal B-1 lymphocytes. J. Immunol. 2003. 171: 1192-1201.
35. + B cells. J. Immunol. 1990. 144: 4520-4525.
36. Hayakawa, K., Asano, M., Shinton, S. A., Gui, M., Wen, L. J., Dashoff, J. and Hardy, R. R., Positive selection of anti-thy-1 autoreactive B-1 cells and natural serum autoantibody production independent from bone marrow B cell development. J. Exp. Med. 2003. 197: 87-99.
37. Izon, D. J., Aster, J. C., He, Y., Weng, A., Karnell, F. G., Patriub, V., Xu, L., Bakkour, S., Rodriguez, C., Allman, D. and Pear, W. S., Deltex1 redirects lymphoid progenitors to the B cell lineage by antagonizing Notch1. Immunity 2002. 16: 231-243.
38. Washburn, T., Schweighoffer, E., Gridley, T., Chang, D., Fowlkes, B. J., Cado, D. and Robey, E., Notch activity influences the alphabeta versus gammadelta T cell lineage decision. Cell 1997. 88: 833-843.
39. Deftos, M. L. and Bevan, M. J., Notch signaling in T cell development. Curr. Opin. Immunol. 2000. 12: 166-172.
40. Rothenberg, E. V., Notchless T cell maturation? Nat. Immunol. 2001. 2: 189-190.
41. Izon, D. J., Punt, J. A., Xu, L., Karnell, F. G., Allman, D., Myung, P. S., Boerth, N. J., Pui, J. C., Koretzky, G. A. and Pear, W. S., Notch1 regulates maturation of CD4+ and CD8+ thymocytes by modulating TCR signal strength. Immunity 2001. 14: 253-264.
42. Liu, Z. G., Smith, S. W., McLaughlin, K. A., Schwartz, L. M. and Osborne, B. A., Apoptotic signals delivered through the T cell receptor of a T cell hybrid require the immediate-early gene nur77. Nature 1994. 367: 281-284.
43. Woronicz, J. D., Calnan, B., Ngo, V. and Winoto, A., Requirement for the orphan steroid receptor Nur77 in apoptosis of T cell hybridomas. Nature 1994. 367: 277-281.
44. Witt, C. M., Won, W. J., Hurez, V. and Klug, C. A., Notch2 haploinsufficiency results in diminished B1 B cells and a severe reduction in marginal zone B cells. J Immunol 2003. 171: 2783-2788.
45. Martin, F., Oliver, A. M. and Kearney, J. F., Marginal zone and B1 B cells unite in the early response against T-independent blood-borne particulate antigens. Immunity 2001. 14: 617-629.
46. Guinamard, R., Okigaki, M., Schlessinger, J. and Ravetch, J. V., Absence of marginal zone B cells in Pyk-2-deficient mice defines their role in the humoral response. Nat. Immunol. 2000. 1: 31-36.
47. Samardzic, T., Marinkovic, D., Nielsen, P. J., Nitschke, L. and Wirth, T., BOB.1/OBF.1 deficiency affects marginal-zone B-cell compartment. Mol. Cell Biol. 2002. 22: 8320-8331.
48. Kretschmer, K., Jungebloud, A., Stopkowicz, J., Kleinke, T., Hoffmann, R. and Weiss, S., The selection of marginal zone B cells differs from that of B-1a cells. J. Immunol. 2003. 171: 6495-6501.
49. Tsuji, R. F., Szczepanik, M., Kawikova, I., Paliwal, V., Campos, R. A., Itakura, A., Akahira-Azuma, M., Baumgarth, N., Herzenberg, L. A. and Askenase, P. W., B cell-dependent T cell responses: IgM antibodies are required to elicit contact sensitivity. J. Exp. Med. 2002. 196: 1277-1290.