Cutting edge commentary: Two B-1 or not to be one

Journal of Immunology

Volumn 168, Issue 9, 2002, Pages 4257-4261

  Rothstein, Thomas L ^a  

^a BOSTON MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; APOPTOSIS; B LYMPHOCYTE; CELL DIFFERENTIATION; CELL KINETICS; CELL LINEAGE; CONTROLLED STUDY; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PERITONEUM CELL; PHENOTYPE; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; SPLEEN CELL; TRANSGENIC MOUSE;

EID: 0036569215     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.168.9.4257     Document Type: Review

References (84)

1. Origin of murine B cell lineages
2. + B (B-1) cells and immunity
3. B cell development pathways
4. The "Ly-1 B" cell subpopulation in normal immunodefective, and autoimmune mice
5. Permanent alteration of the murine Ly-1 B repertoire due to selective depletion of Ly-1 B cells in neonatal animals
6. Immunofluorescence analysis of B-1 cell ontogeny in the mouse
7. Peritoneal Ly-1 B cells: Genetic control, autoantibody production, increased γ light chain expression
8. Anti-Ig Ab inhibits the phorbol ester-induced stimulation of peritoneal B cells
9. Decreased surface IgM receptor-mediated activation of phospholipase Cγ2 in B-1 lymphocytes
10. CD5-mediated negative regulation of antigen receptor-induced growth signals in B-1 B cells
11. Negative regulation of antigen receptor-mediated signaling by constitutive association of CD5 with the SHP-1 protein tyrosine phosphatase in B-1 B cells
12. Peritoneal B cells respond to phorbol esters in the absence of co-mitogen
13. Early induction of cyclin D2 expression in phorbol ester-responsive B-1 lymphocytes
14. Cutting edge: Differences in the signaling requirements for activation of assembled cyclin D3-cdk4 complexes in B-1 and B-2 lymphocytes
15. + B cells in viable moth-eaten and normal mice
16. + B cells upon transfer of peritoneal cells into allotype-congenic, newborn mice
17. Evidence that intestinal IgA plasma cells in μκ transgenic mice are derived from B-1 (Ly-1 B) cells
18. Continuous antiinterleukin 10 Ab administration depletes mice of Ly-1 B cells but not conventional B cells
19. + B cell lymphomas
20. Germline Ab V regions as determinants of clonal persistence and malignant growth in the B cell compartment
21. Lack of N regions in fetal and neonatal mouse immunoglobulin V-D-J junctional sequences
22. Sequence homologies, N sequence insertion and JH gene utilization in VHDJH joining: Implications for the joining mechanism and the ontogenetic timing of Ly1 B cell and B-CLL progenitor generation
23. + (CD5) B cells
24. A single VH gene is utilized predominantly in anti-BrMRBC hybridomas derived from purified Ly-1 B cells: Definition of the VH11 family
25. + B cells
26. + B lymphocytes
27. The primary B cell response to the O/core region of bacterial lipopolysaccharide is restricted to the Ly-1 lineage
28. Marginal zone and B1 B cells unite in the early response against T-independent blood-borne particulate antigens
29. Anti-phosphorylcholine Abs of the T15 idiotype are optimally protective against Streptococcus pneumoniae
30. Many of the IgA producing plasma cells in murine gut are derived from self-replenishing precursors in the peritoneal cavity
31. A critical role of natural immunoglobulin M in immediate defense against systemic bacterial infection
32. Control of early viral and bacterial distribution and disease by natural Abs
33. B-1 and B-2 cell-derived immunoglobulin M Abs are nonredundant components of the protective response to influenza virus infection
34. + B cells from patients with rheumatoid arthritis
35. B cells expressing CD5 are increased in Sjögren's syndrome
36. Prevention of autoimmune symptoms in autoimmune-prone mice by elimination of B-1 cells
37. Ly-1 B cells: Functionally distinct lymphocytes that secrete IgM autoantibodies
38. + B cell lymphoma, CH12, expressing isotypes other than IgM
39. + B) cells make somatically hypermutated high-affinity IgM rheumatoid factors
40. Infrequent normal B lymphocytes express features of B-chronic lymphocytic leukemia
41. Ly-1 B-cell clones similar to human chronic lymphocytic leukemias routinely develop in older normal mice and young autoimmune (New Zealand Black-related) animals
42. The natural history of a lymphoproliferative disorder in aged NZB mice
43. Progenitors for Ly-1 B cells are distinct from progenitors for other B cells
44. Immunoglobulin-bearing B cells reconstitute and maintain the murine Ly-1 B cell lineage
45. Differential development of progenitor activity for three B-cell lineages
46. An embryonic source of Ly1 but not conventional B cells
47. A developmental switch in B lymphopoiesis
48. Para-aortic splanchnopleura from early mouse embryos contains B1a cell progenitors
49. B-1 cells: The lineage question revisited
50. - B cells with anti-1g, but not LPS, induces surface CD5: Two B-cell activation pathways
51. Induction of phorbol ester responsiveness in conventional B cells after activation via surface Ig
52. Development of B-1 cells: Segregation of phosphatidyl choline-specific B cells to the B-1 population occurs after immunoglobulin gene expression
53. Cutting edge commentary: Origins of B-1 cells
54. Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene
55. SHP-1 deficiency in B-lineage cells is associated with heightened lyn protein expression and increased lyn kinase activity
56. B cell antigen receptor specificity and surface density together determine B-1 versus B-2 cell development
57. Expression levels of B cell surface immunoglobulin regulate efficiency of allelic exclusion and size of autoreactive B-1 cell compartment
58. + B cell precursor in B-1 cell differentiation
59. + B cells
60. CD43 (S7) expression identifies peripheral B cell subsets
61. + B cells both in vivo and in vitro
62. CXCL13 is required for B1 cell homing, natural Ab production, and body cavity immunity
63. Mac-1-negative B-1b phenotype of natural Ab-producing cells, including those responding to Ga1α1,3Ga1 epitopes in α1,3-galactosyltransferase-deficient mice
64. Splenic and peritoneal B-1 cells are distinct populations as defined by transcriptional and proliferative features that separate peritoneal B-1 from splenic B-2 cells
65. Aiolos regulates B cell activation and maturation to effector state
66. The B-cell-specific transcription coactivator OCA-B/OBF-1/Bob-1 is essential for normal production of immunoglobulin isotypes
67. -/- mice
68. Secondary V(D)J recombination in B-1 cells
69. TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease: Impaired B cell maturation in mice lacking BLyS
70. -/- mice
71. Cyclin D2 is essential for BCR-mediated proliferation and CD5 B cell development
72. Positive selection of natural autoreactive B cells
73. Abnormal transcription factor induction through the surface immunoglobulin M receptor of B-1 lymphocytes
74. A novel mechanism for B cell repertoire maturation based on response by B cell precursors to pre-B receptor assembly
75. Response by B cell precursors to pre-B receptor assembly: Differences between fetal liver and bone marrow
76. A novel regulatory myosin light chain gene distinguishes pre-B cell subsets and is IL-7 inducible
77. The regulated expression of B lineage associated genes during B cell differentiation in bone marrow and fetal liver
78. Absence of MHC class II expression distinguishes fetal from adult B lymphopoiesis in mice
79. CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: Altered signaling in CD22-deficient mice
80. CD19 regulates B lymphocyte signaling thresholds critical for the development of B-1 lineage cells and autoimmunity
81. Receptor selection in B and T lymphocytes
82. Balancing immunity and tolerance: Deleting and tuning lymphocyte repertoires
83. B-cell receptor and Fas-mediated signals for life and death
84. CD5 maintains tolerance in anergic B cells