Hydroxytyrosol induces phase II detoxifying enzyme expression and effectively protects dopaminergic cells against dopamine- and 6-hydroxydopamine induced cytotoxicity

Neurochemistry International

Volumn 96, Issue , 2016, Pages 113-120

  Yu, Guohua ^a   Deng, Ajun ^a   Tang, Wanbin ^a   Ma, Junzhi ^a   Yuan, Chonggang ^a   Ma, Jiyan ^a,b  

^a B326 Science Building   (China)

^b VAN ANDEL RESEARCH INSTITUTE   (United States)

Author keywords

Dopamine; Hydroxytyrosol; Oxidative stress; Parkinson's disease

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; DICOUMAROL; DOPAMINE; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE M2; GLUTATHIONE TRANSFERASE M4; GLUTATHIONE TRANSFERASE M5; HEME OXYGENASE 1; HYDROXYTYROSOL; OXIDOPAMINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); TRANSFERASE; UNCLASSIFIED DRUG; 3,4-DIHYDROXYPHENYLETHANOL; ANTIOXIDANT; CYTOTOXIN; NEUROPROTECTIVE AGENT; NQO1 PROTEIN, HUMAN; PHENETHYL ALCOHOL;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DOPAMINERGIC NERVE CELL; DRUG DETOXIFICATION; DRUG EFFICACY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL LINE; NEUROPROTECTION; NEUROTOXICITY; NEUROTOXICOLOGY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SH SY5Y CELL LINE; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECTS; ENZYME INDUCTION; METABOLISM; PHYSIOLOGY; TUMOR CELL LINE; XENOBIOTIC METABOLISM;

ANTIOXIDANTS; CELL LINE, TUMOR; CELL SURVIVAL; CYTOTOXINS; DOPAMINE; DOPAMINERGIC NEURONS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INDUCTION; HUMANS; METABOLIC DETOXICATION, PHASE II; NAD(P)H DEHYDROGENASE (QUINONE); NEUROPROTECTIVE AGENTS; OXIDOPAMINE; PHENYLETHYL ALCOHOL;

EID: 84962515378     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2016.03.005     Document Type: Article

References (53)

1. F. Barzi, M. Woodward, R.M. Marfisi, L. Tavazzi, F. Valagussa, R. Marchioli, and G.I.-P. Investigators Mediterranean diet and all-causes mortality after myocardial infarction: results from the GISSI-Prevenzione trial Eur. J. Clin. Nutr. 57 2003 604 611
2. J.M. Beitz Parkinson's disease: a review Front. Biosci. Sch. Ed. 6 2014 65 74
3. A. Bellucci, N.B. Mercuri, A. Venneri, G. Faustini, F. Longhena, M. Pizzi, C. Missale, and P. Spano Parkinson's disease: from synaptic loss to connectome dysfunction Neuropathol. Appl. Neurobiol. 42 2016 77 94
4. J. Blesa, I. Trigo-Damas, A. Quiroga-Varela, and V.R. Jackson-Lewis Oxidative stress and Parkinson's disease Front. Neuroanat. 9 2015 91
5. K. Cao, J. Xu, X. Zou, Y. Li, C. Chen, A. Zheng, H. Li, H. Li, I.M. Szeto, Y. Shi, J. Long, J. Liu, and Z. Feng Hydroxytyrosol prevents diet-induced metabolic syndrome and attenuates mitochondrial abnormalities in obese mice Free Radic. Biol. Med. 67 2014 396 407
6. G. Cavelier, and L.M. Amzel Mechanism of NAD(P)H:quinone reductase: Ab initio studies of reduced flavin Proteins 43 2001 420 432
7. L.W. Chen, Y.Q. Wang, L.C. Wei, M. Shi, and Y.S. Chan Chinese herbs and herbal extracts for neuroprotection of dopaminergic neurons and potential therapeutic treatment of Parkinson's disease CNS Neurol. Disord. Drug Targets 6 2007 273 281
8. M. Cieslik, J. Pyszko, and J.B. Strosznajder Docosahexaenoic acid and tetracyclines as promising neuroprotective compounds with poly(ADP-ribose) polymerase inhibitory activities for oxidative/genotoxic stress treatment Neurochem. Int. 62 2013 626 636
9. D.G. Cornwell, and J. Ma Studies in vitamin E: biochemistry and molecular biology of tocopherol quinones Vitam. Horm. 76 2007 99 134
10. D.G. Cornwell, and J. Ma Nutritional benefit of olive oil: the biological effects of hydroxytyrosol and its arylating quinone adducts J. Agric. Food Chem. 56 2008 8774 8786
11. S.R. Danielson, and J.K. Andersen Oxidative and nitrative protein modifications in Parkinson's disease Free Radic. Biol. Med. 44 2008 1787 1794
12. M. De Lorgeril, P. Salen, J.L. Martin, N. Mamelle, I. Monjaud, P. Touboul, and J. Delaye Effect of a mediterranean type of diet on the rate of cardiovascular complications in patients with coronary artery disease. Insights into the cardioprotective effect of certain nutriments J. Am. Coll. Cardiol. 28 1996 1103 1108
13. V. Dias, E. Junn, and M.M. Mouradian The role of oxidative stress in Parkinson's disease J. Park. Dis. 3 2013 461 491
14. J.L. Eriksen, T.M. Dawson, D.W. Dickson, and L. Petrucelli Caught in the act: alpha-synuclein is the culprit in Parkinson's disease Neuron 40 2003 453 456
15. S. Fahn A pilot trial of high-dose alpha-tocopherol and ascorbate in early Parkinson's disease Ann. Neurol. 32 Suppl. l 1992 S128 S132
16. C. Feart, C. Samieri, V. Rondeau, H. Amieva, F. Portet, J.F. Dartigues, N. Scarmeas, and P. Barberger-Gateau Adherence to a Mediterranean diet, cognitive decline, and risk of dementia JAMA 302 2009 638 648
17. B. Fornstedt, E. Rosengren, and A. Carlsson Occurrence and distribution of 5-S-cysteinyl derivatives of dopamine, dopa and dopac in the brains of eight mammalian species Neuropharmacology 25 1986 451 454
18. C.C. Franklin, D.S. Backos, I. Mohar, C.C. White, H.J. Forman, and T.J. Kavanagh Structure, function, and post-translational regulation of the catalytic and modifier subunits of glutamate cysteine ligase Mol. Asp. Med. 30 2009 86 98
19. J.A. Gonzalez-Correa, M.D. Navas, J.A. Lopez-Villodres, M. Trujillo, J.L. Espartero, and J.P. De La Cruz Neuroprotective effect of hydroxytyrosol and hydroxytyrosol acetate in rat brain slices subjected to hypoxia-reoxygenation Neurosci. Lett. 446 2008 143 146
20. D.G. Graham, S.M. Tiffany, W.R. Bell Jr., and W.F. Gutknecht Autoxidation versus covalent binding of quinones as the mechanism of toxicity of dopamine, 6-hydroxydopamine, and related compounds toward C1300 neuroblastoma cells in vitro Mol. Pharmacol. 14 1978 644 653
21. S. Granados-Principal, N. El-Azem, R. Pamplona, C. Ramirez-Tortosa, M. Pulido-Moran, L. Vera-Ramirez, J.L. Quiles, P. Sanchez-Rovira, A. Naudi, M. Portero-Otin, P. Perez-Lopez, and M. Ramirez-Tortosa Hydroxytyrosol ameliorates oxidative stress and mitochondrial dysfunction in doxorubicin-induced cardiotoxicity in rats with breast cancer Biochem. Pharmacol. 90 2014 25 33
22. J.M. Han, Y.J. Lee, S.Y. Lee, E.M. Kim, Y. Moon, H.W. Kim, and O. Hwang Protective effect of sulforaphane against dopaminergic cell death J. Pharmacol. Exp. Ther. 321 2007 249 256
23. T. Hashimoto, M. Ibi, K. Matsuno, S. Nakashima, T. Tanigawa, T. Yoshikawa, and C. Yabe-Nishimura An endogenous metabolite of dopamine, 3,4-dihydroxyphenylethanol, acts as a unique cytoprotective agent against oxidative stress-induced injury Free Radic. Biol. Med. 36 2004 555 564
24. T.G. Hastings The role of dopamine oxidation in mitochondrial dysfunction: implications for Parkinson's disease J. Bioenerg. Biomembr. 41 2009 469 472
25. T.G. Hastings, D.A. Lewis, and M.J. Zigmond Role of oxidation in the neurotoxic effects of intrastriatal dopamine injections Proc. Natl. Acad. Sci. USA 93 1996 1956 1961
26. N.N.-P. Investigators A randomized clinical trial of coenzyme Q10 and GPI-1485 in early Parkinson disease Neurology 68 2007 20 28
27. T. Jansen, and A. Daiber Direct antioxidant properties of bilirubin and biliverdin. Is there a role for biliverdin reductase? Front. Pharmacol. 3 2012 30
28. P. Joseph, D.J. Long 2nd, A.J. Klein-Szanto, and A.K. Jaiswal Role of NAD(P)H:quinone oxidoreductase 1 (DT diaphorase) in protection against quinone toxicity Biochem. Pharmacol. 60 2000 207 214
29. A.R. Khalatbary Olive oil phenols and neuroprotection Nutr. Neurosci. 16 2013 243 249
30. K.A. Koo, S.H. Kim, T.H. Oh, and Y.C. Kim Acteoside and its aglycones protect primary cultures of rat cortical cells from glutamate-induced excitotoxicity Life Sci. 79 2006 709 716
31. C. Luo, Y. Li, H. Wang, Y. Cui, Z. Feng, H. Li, Y. Li, Y. Wang, K. Wurtz, P. Weber, J. Long, and J. Liu Hydroxytyrosol promotes superoxide production and defects in autophagy leading to anti-proliferation and apoptosis on human prostate cancer cells Curr. Cancer Drug Targets 13 2013 625 639
32. C.W. Olanow Levodopa: effect on cell death and the natural history of Parkinson's disease Mov. Disord. 30 2015 37 44
33. H. Pasban-Aliabadi, S. Esmaeili-Mahani, V. Sheibani, M. Abbasnejad, A. Mehdizadeh, and M.M. Yaghoobi Inhibition of 6-hydroxydopamine-induced PC12 cell apoptosis by olive (Olea europaea L.) leaf extract is performed by its main component oleuropein Rejuvenation Res. 16 2013 134 142
34. V. Pittala, L. Salerno, G. Romeo, M.N. Modica, and M.A. Siracusa A focus on heme oxygenase-1 (HO-1) inhibitors Curr. Med. Chem. 20 2013 3711 3732
35. H.J. Prochaska, and A.B. Santamaria Direct measurement of NAD(P)H:quinone reductase from cells cultured in microtiter wells: a screening assay for anticarcinogenic enzyme inducers Anal. Biochem. 169 1988 328 336
36. S. Rajasankar, T. Manivasagam, and S. Surendran Ashwagandha leaf extract: a potential agent in treating oxidative damage and physiological abnormalities seen in a mouse model of Parkinson's disease Neurosci. Lett. 454 2009 11 15
37. N. Richard, S. Arnold, U. Hoeller, C. Kilpert, K. Wertz, and J. Schwager Hydroxytyrosol is the major anti-inflammatory compound in aqueous olive extracts and impairs cytokine and chemokine production in macrophages Planta Med. 77 2011 1890 1897
38. G. Ristagno, F. Fumagalli, C. Porretta-Serapiglia, A. Orru, C. Cassina, M. Pesaresi, S. Masson, L. Villanova, A. Merendino, A. Villanova, L. Cervo, G. Lauria, R. Latini, and R. Bianchi Hydroxytyrosol attenuates peripheral neuropathy in streptozotocin-induced diabetes in rats J. Agric. Food Chem. 60 2012 5859 5865
39. J. Rodriguez-Morato, L. Xicota, M. Fito, M. Farre, M. Dierssen, and R. de la Torre Potential role of olive oil phenolic compounds in the prevention of neurodegenerative diseases Molecules 20 2015 4655 4680
40. M.C. Rodriguez-Oroz, M. Jahanshahi, P. Krack, I. Litvan, R. Macias, E. Bezard, and J.A. Obeso Initial clinical manifestations of Parkinson's disease: features and pathophysiological mechanisms Lancet Neurol. 8 2009 1128 1139
41. A.H. Schapira Complex I: inhibitors, inhibition and neurodegeneration Exp. Neurol. 224 2010 331 335
42. T.W. Sedlak, M. Saleh, D.S. Higginson, B.D. Paul, K.R. Juluri, and S.H. Snyder Bilirubin and glutathione have complementary antioxidant and cytoprotective roles Proc. Natl. Acad. Sci. USA 106 2009 5171 5176
43. J. Segura-Aguilar, I. Paris, P. Munoz, E. Ferrari, L. Zecca, and F.A. Zucca Protective and toxic roles of dopamine in Parkinson's disease J. Neurochem. 129 2014 898 915
44. D. Sulzer, and L. Zecca Intraneuronal dopamine-quinone synthesis: a review Neurotox. Res. 1 2000 181 195
45. A. Trichopoulou Traditional Mediterranean diet and longevity in the elderly: a review Public Health Nutr. 7 2004 943 947
46. A. Trichopoulou, T. Costacou, C. Bamia, and D. Trichopoulos Adherence to a Mediterranean diet and survival in a Greek population N. Engl. J. Med. 348 2003 2599 2608
47. N. Wang, Y. Wang, G. Yu, C. Yuan, and J. Ma Quinoprotein adducts accumulate in the substantia nigra of aged rats and correlate with dopamine-induced toxicity in SH-SY5Y cells Neurochem. Res. 36 2011 2169 2175
48. X. Wang, B. Thomas, R. Sachdeva, L. Arterburn, L. Frye, P.G. Hatcher, D.G. Cornwell, and J. Ma Mechanism of arylating quinone toxicity involving Michael adduct formation and induction of endoplasmic reticulum stress Proc. Natl. Acad. Sci. USA 103 2006 3604 3609
49. G. Yu, H. Liu, W. Zhou, X. Zhu, C. Yu, N. Wang, Y. Zhang, J. Ma, Y. Zhao, Y. Xu, L. Liao, H. Ji, C. Yuan, and J. Ma In vivo protein targets for increased quinoprotein adduct formation in aged substantia nigra Exp. Neurol. 271 2015 13 24
50. K.S. Zafar, S.H. Inayat-Hussain, D. Siegel, A. Bao, B. Shieh, and D. Ross Overexpression of NQO1 protects human SK-N-MC neuroblastoma cells against dopamine-induced cell death Toxicol. Lett. 166 2006 261 267
51. L. Zhu, Z. Liu, Z. Feng, J. Hao, W. Shen, X. Li, L. Sun, E. Sharman, Y. Wang, K. Wertz, P. Weber, X. Shi, and J. Liu Hydroxytyrosol protects against oxidative damage by simultaneous activation of mitochondrial biogenesis and phase II detoxifying enzyme systems in retinal pigment epithelial cells J. Nutr. Biochem. 21 2010 1089 1098
52. A. Zimprich, S. Biskup, P. Leitner, P. Lichtner, M. Farrer, S. Lincoln, J. Kachergus, M. Hulihan, R.J. Uitti, D.B. Calne, A.J. Stoessl, R.F. Pfeiffer, N. Patenge, I.C. Carbajal, P. Vieregge, F. Asmus, B. Muller-Myhsok, D.W. Dickson, T. Meitinger, T.M. Strom, Z.K. Wszolek, and T. Gasser Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology Neuron 44 2004 601 607
53. F.A. Zucca, J. Segura-Aguilar, E. Ferrari, P. Munoz, I. Paris, D. Sulzer, T. Sarna, L. Casella, and L. Zecca Interactions of iron, dopamine and neuromelanin pathways in brain aging and Parkinson's disease Prog. Neurobiol. 2015