메뉴 건너뛰기




Volumn 7, Issue FEB, 2016, Pages

The miRNA journey from theory to practice as a CNS biomarker

Author keywords

Biomarker; Central nervous system (CNS); Cerebrospinal fluid (CSF); MicroRNA; Neurodegenerative disease

Indexed keywords

INTERLEUKIN 6; INTERLEUKIN 8; MICRORNA; MICRORNA 107; MICRORNA 125B; MICRORNA 132 3P; MICRORNA 132 5P; MICRORNA 143 3P; MICRORNA 143 5P; MICRORNA 181C; MICRORNA 21; MICRORNA 210; MICRORNA 216A; MICRORNA 26B; MICRORNA 27A; MICRORNA 29A; MICRORNA 338 3P; MICRORNA 633; MICRORNA 802; MICRORNA 9; MICRORNA 922; MICRORNA LET 7B; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84962514463     PISSN: None     EISSN: 16648021     Source Type: Journal    
DOI: 10.3389/fgene.2016.00011     Document Type: Review
Times cited : (79)

References (81)
  • 1
    • 84962597237 scopus 로고    scopus 로고
    • Does post-operative cognitive decline promote/accelerate Alzheimer's disease pathology? Perioperative cerebrospinal fluid biomarkers and the gap of knowledge
    • Ackermann, W., Stoicea, N., Wojda, T. R., Steiner, N., Barnett, C. J., and Bergese, S. D. (2014). Does post-operative cognitive decline promote/accelerate Alzheimer's disease pathology? Perioperative cerebrospinal fluid biomarkers and the gap of knowledge. Aust. J. Anesth. Anal. 2:1038.
    • (2014) Aust. J. Anesth. Anal , vol.2 , pp. 1038
    • Ackermann, W.1    Stoicea, N.2    Wojda, T.R.3    Steiner, N.4    Barnett, C.J.5    Bergese, S.D.6
  • 2
    • 84886938691 scopus 로고    scopus 로고
    • MiR-21 in the extracellular vesicles (EVs) of cerebrospinal fluid (CSF): a platform for glioblastoma biomarker development
    • Akers, J. C., Ramakrishnan, V., Kim, R., Skog, J., Nakano, I., Pingle, S., et al. (2013). MiR-21 in the extracellular vesicles (EVs) of cerebrospinal fluid (CSF): a platform for glioblastoma biomarker development. PLoS ONE 8:e78115. doi: 10.1371/journal.pone.0078115
    • (2013) PLoS ONE , vol.8
    • Akers, J.C.1    Ramakrishnan, V.2    Kim, R.3    Skog, J.4    Nakano, I.5    Pingle, S.6
  • 3
    • 84871695724 scopus 로고    scopus 로고
    • microRNA (miRNA) speciation in Alzheimer's disease (AD) cerebrospinal fluid (CSF) and extracellular fluid (ECF)
    • Alexandrov, P. N., Dua, P., Hill, J. M., Bhattacharjee, S., Zhao, Y., and Lukiw, W. J. (2012). microRNA (miRNA) speciation in Alzheimer's disease (AD) cerebrospinal fluid (CSF) and extracellular fluid (ECF). Int. J. Biochem. Mol. Biol. 3, 365-373.
    • (2012) Int. J. Biochem. Mol. Biol , vol.3 , pp. 365-373
    • Alexandrov, P.N.1    Dua, P.2    Hill, J.M.3    Bhattacharjee, S.4    Zhao, Y.5    Lukiw, W.J.6
  • 4
    • 58149379604 scopus 로고    scopus 로고
    • MicroRNA-338 regulates local cytochrome c oxidase IV mRNA levels and oxidative phosphorylation in the axons of sympathetic neurons
    • Aschrafi, A., Schwechter, A. D., Mameza, M. G., Natera-Naranjo, O., Gioio, A. E., and Kaplan, B. B. (2008). MicroRNA-338 regulates local cytochrome c oxidase IV mRNA levels and oxidative phosphorylation in the axons of sympathetic neurons. J. Neurosci. 28, 12581-12590. doi: 10.1523/JNEUROSCI.3338-08.2008
    • (2008) J. Neurosci , vol.28 , pp. 12581-12590
    • Aschrafi, A.1    Schwechter, A.D.2    Mameza, M.G.3    Natera-Naranjo, O.4    Gioio, A.E.5    Kaplan, B.B.6
  • 5
    • 84860279695 scopus 로고    scopus 로고
    • MicroRNA let-7i is a promising serum biomarker for blast-induced traumatic brain injury
    • Balakathiresan, N., Bhomia, M., Chandran, R., Chavko, M., McCarron, R. M., and Maheshwari, R. K. (2012). MicroRNA let-7i is a promising serum biomarker for blast-induced traumatic brain injury. J. Neurotrauma 29, 1379-1387. doi: 10.1089/neu.2011.2146
    • (2012) J. Neurotrauma , vol.29 , pp. 1379-1387
    • Balakathiresan, N.1    Bhomia, M.2    Chandran, R.3    Chavko, M.4    McCarron, R.M.5    Maheshwari, R.K.6
  • 6
    • 79953103395 scopus 로고    scopus 로고
    • Identification of microRNAs in the cerebrospinal fluid as marker for primary diffuse large B-cell lymphoma of the central nervous system
    • Baraniskin, A., Kuhnhenn, J., Schlegel, U., Chan, A., Deckert, M., Gold, R., et al. (2011). Identification of microRNAs in the cerebrospinal fluid as marker for primary diffuse large B-cell lymphoma of the central nervous system. Blood 117, 3140-3146. doi: 10.1182/blood-2010-09-308684
    • (2011) Blood , vol.117 , pp. 3140-3146
    • Baraniskin, A.1    Kuhnhenn, J.2    Schlegel, U.3    Chan, A.4    Deckert, M.5    Gold, R.6
  • 7
    • 84856250078 scopus 로고    scopus 로고
    • Identification of microRNAs in the cerebrospinal fluid as biomarker for the diagnosis of glioma
    • Baraniskin, A., Kuhnhenn, J., Schlegel, U., Maghnouj, A., Zöllner, H., Schmiegel, W., et al. (2012b). Identification of microRNAs in the cerebrospinal fluid as biomarker for the diagnosis of glioma. Neuro-oncology 14, 29-33. doi: 10.1093/neuonc/nor169
    • (2012) Neuro-oncology , vol.14 , pp. 29-33
    • Baraniskin, A.1    Kuhnhenn, J.2    Schlegel, U.3    Maghnouj, A.4    Zöllner, H.5    Schmiegel, W.6
  • 8
    • 84866047835 scopus 로고    scopus 로고
    • MicroRNAs in cerebrospinal fluid as biomarker for disease course monitoring in primary central nervous system lymphoma
    • Baraniskin, A., Kuhnhenn, J., Schlegel, U., Schmiegel, W., Hahn, S., and Schroers, R. (2012a). MicroRNAs in cerebrospinal fluid as biomarker for disease course monitoring in primary central nervous system lymphoma. J. Neurooncol. 109, 239-244. doi: 10.1007/s11060-012-0908-2
    • (2012) J. Neurooncol , vol.109 , pp. 239-244
    • Baraniskin, A.1    Kuhnhenn, J.2    Schlegel, U.3    Schmiegel, W.4    Hahn, S.5    Schroers, R.6
  • 9
    • 0141620181 scopus 로고    scopus 로고
    • Structural and functional aspects of the blood-brain barrier
    • Begley, D. J., and Brightman, M. W. (2003). Structural and functional aspects of the blood-brain barrier. Prog. Drug Res. 6, 19-78. doi: 10.1007/978-3-0348-8049-7_2
    • (2003) Prog. Drug Res , vol.6 , pp. 19-78
    • Begley, D.J.1    Brightman, M.W.2
  • 11
    • 0025339140 scopus 로고
    • Blood-brain barrier disturbance in patients with Alzheimer's disease is related to vascular factors
    • Blennow, K., Wallin, A., Fredman, P., Karlsson, I., Gottfries, C. G., and Svennerholm, L. (1990). Blood-brain barrier disturbance in patients with Alzheimer's disease is related to vascular factors. Acta Neurol. Scand. 81, 323-326. doi: 10.1111/j.1600-0404.1990.tb01563.x
    • (1990) Acta Neurol. Scand , vol.81 , pp. 323-326
    • Blennow, K.1    Wallin, A.2    Fredman, P.3    Karlsson, I.4    Gottfries, C.G.5    Svennerholm, L.6
  • 13
    • 84990967378 scopus 로고    scopus 로고
    • SNAP-25 is a promising novel cerebrospinal fluid biomarker for synapse degeneration in Alzheimer's disease
    • Brinkmalm, A., Brinkmalm, G., Honer, W. G., Frölich, L., Hausner, L., Minthon, L., et al. (2014). SNAP-25 is a promising novel cerebrospinal fluid biomarker for synapse degeneration in Alzheimer's disease. Mol. Neurodegener. 9:53. doi: 10.1186/1750-1326-9-53
    • (2014) Mol. Neurodegener , vol.9 , pp. 53
    • Brinkmalm, A.1    Brinkmalm, G.2    Honer, W.G.3    Frölich, L.4    Hausner, L.5    Minthon, L.6
  • 14
    • 84876581756 scopus 로고    scopus 로고
    • Identification of extracellular miRNA in human cerebrospinal fluid by next-generation sequencing
    • Burgos, K. L., Javaherian, A., Bomprezzi, R., Ghaffari, L., Rhodes, S., Courtright, A., et al. (2013). Identification of extracellular miRNA in human cerebrospinal fluid by next-generation sequencing. RNA 19, 712-722. doi: 10.1261/rna.036863.112
    • (2013) RNA , vol.19 , pp. 712-722
    • Burgos, K.L.1    Javaherian, A.2    Bomprezzi, R.3    Ghaffari, L.4    Rhodes, S.5    Courtright, A.6
  • 15
    • 84900430088 scopus 로고    scopus 로고
    • Profiles of extracellular miRNA in cerebrospinal fluid and serum from patients with Alzheimer's and Parkinson's diseases correlate with disease status and features of pathology
    • Burgos, K., Malenica, I., Metpally, R., Courtright, A., Rakela, B., Beach, T., et al. (2014). Profiles of extracellular miRNA in cerebrospinal fluid and serum from patients with Alzheimer's and Parkinson's diseases correlate with disease status and features of pathology. PLoS ONE 9:e94839. doi: 10.1371/journal.pone.0094839
    • (2014) PLoS ONE , vol.9
    • Burgos, K.1    Malenica, I.2    Metpally, R.3    Courtright, A.4    Rakela, B.5    Beach, T.6
  • 16
    • 18744396337 scopus 로고    scopus 로고
    • Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
    • Calin, G. A., Dumitru, C. D., Shimizu, M., Bichi, R., Zupo, S., Noch, E., et al. (2002). Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc. Natl. Acad. Sci. U.S.A. 99, 15524-15529. doi: 10.1073/pnas.242606799
    • (2002) Proc. Natl. Acad. Sci. U.S.A , vol.99 , pp. 15524-15529
    • Calin, G.A.1    Dumitru, C.D.2    Shimizu, M.3    Bichi, R.4    Zupo, S.5    Noch, E.6
  • 17
    • 84872195111 scopus 로고    scopus 로고
    • The path to microRNA therapeutics in psychiatric and neurodegenerative disorders
    • Chan, A. W., and Kocerha, J. (2012). The path to microRNA therapeutics in psychiatric and neurodegenerative disorders. Front. Genet. 3:82. doi: 10.3389/fgene.2012.00082
    • (2012) Front. Genet , vol.3 , pp. 82
    • Chan, A.W.1    Kocerha, J.2
  • 18
    • 84883492783 scopus 로고    scopus 로고
    • The detection of microRNA associated with Alzheimer's disease in biological fluids using next-generation sequencing technologies
    • Cheng, L., Quek, C. Y., Sun, X., Bellingham, S. A., and Hill, A. F. (2013). The detection of microRNA associated with Alzheimer's disease in biological fluids using next-generation sequencing technologies. Front. Genet. 4:150. doi: 10.3389/fgene.2013.00150
    • (2013) Front. Genet , vol.4 , pp. 150
    • Cheng, L.1    Quek, C.Y.2    Sun, X.3    Bellingham, S.A.4    Hill, A.F.5
  • 19
    • 84939935120 scopus 로고    scopus 로고
    • MicroRNAs as potential circulating biomarkers for amyotrophic lateral sclerosis
    • Cloutier, F., Marrero, A., O'Connell, C., and Morin, P., Jr. (2015). MicroRNAs as potential circulating biomarkers for amyotrophic lateral sclerosis. J. Mol. Neurosci. 56, 102-112. doi: 10.1007/s12031-014-0471-8
    • (2015) J. Mol. Neurosci , vol.56 , pp. 102-112
    • Cloutier, F.1    Marrero, A.2    O'Connell, C.3    Morin, P.4
  • 20
    • 47849124269 scopus 로고    scopus 로고
    • Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways
    • Cogswell, J. P., Ward, J., Taylor, I. A., Waters, M., Shi, Y., Cannon, B., et al. (2008). Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways. J. Alzheimers Dis. 14, 27-41.
    • (2008) J. Alzheimers Dis , vol.14 , pp. 27-41
    • Cogswell, J.P.1    Ward, J.2    Taylor, I.A.3    Waters, M.4    Shi, Y.5    Cannon, B.6
  • 21
    • 84861970101 scopus 로고    scopus 로고
    • Brain injury biomarkers may improve the predictive power of the IMPACT outcome calculator
    • Czeiter, E., Mondello, S., Kovacs, N., Sandor, J., Gabrielli, A., Schmid, K., et al. (2012). Brain injury biomarkers may improve the predictive power of the IMPACT outcome calculator. J. Neurotrauma 29, 1770-1778. doi: 10.1089/neu.2011.2127
    • (2012) J. Neurotrauma , vol.29 , pp. 1770-1778
    • Czeiter, E.1    Mondello, S.2    Kovacs, N.3    Sandor, J.4    Gabrielli, A.5    Schmid, K.6
  • 22
    • 84919475780 scopus 로고    scopus 로고
    • miR-338-3p is over-expressed in blood, CFS, serum and spinal cord from sporadic amyotrophic lateral sclerosis patients
    • De Felice, B., Annunziata, A., Fiorentino, G., Borra, M., Biffali, E., Coppola, C., et al. (2014). miR-338-3p is over-expressed in blood, CFS, serum and spinal cord from sporadic amyotrophic lateral sclerosis patients. Neurogenetics 15, 243-253. doi: 10.1007/s10048-014-0420-2
    • (2014) Neurogenetics , vol.15 , pp. 243-253
    • De Felice, B.1    Annunziata, A.2    Fiorentino, G.3    Borra, M.4    Biffali, E.5    Coppola, C.6
  • 23
    • 77952583639 scopus 로고    scopus 로고
    • MicroRNAs as biomarkers for CNS cancer and other disorders
    • De Smaele, E., Ferretti, E., and Gulino, A. (2010). MicroRNAs as biomarkers for CNS cancer and other disorders. Brain Res. 133, 800-811. doi: 10.1016/j.brainres.2010.03.103
    • (2010) Brain Res , vol.133 , pp. 800-811
    • De Smaele, E.1    Ferretti, E.2    Gulino, A.3
  • 24
    • 84858330248 scopus 로고    scopus 로고
    • Importance of RNA isolation methods for analysis of exosomal RNA: evaluation of different methods
    • Eldh, M., Lötvall, J., Malmhäll, C., and Ekström, K. (2012). Importance of RNA isolation methods for analysis of exosomal RNA: evaluation of different methods. Mol. Immunol. 50, 278-286. doi: 10.1016/j.molimm.2012.02.001
    • (2012) Mol. Immunol , vol.50 , pp. 278-286
    • Eldh, M.1    Lötvall, J.2    Malmhäll, C.3    Ekström, K.4
  • 25
    • 53549129980 scopus 로고    scopus 로고
    • Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells
    • Ferretti, E., De Smaele, E., Miele, E., Laneve, P., Po, A., Pelloni, M., et al. (2008). Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells. EMBO J. 27, 2616-2627. doi: 10.1038/emboj.2008.172
    • (2008) EMBO J , vol.27 , pp. 2616-2627
    • Ferretti, E.1    De Smaele, E.2    Miele, E.3    Laneve, P.4    Po, A.5    Pelloni, M.6
  • 26
    • 85005808152 scopus 로고    scopus 로고
    • Systemic dysregulation of TDP-43 binding microRNAs in amyotrophic lateral sclerosis
    • Freischmidt, A., Müller, K., Ludolph, A. C., and Weishaupt, J. H. (2013). Systemic dysregulation of TDP-43 binding microRNAs in amyotrophic lateral sclerosis. Acta Neuropathol. Commun. 1:42. doi: 10.1186/2051-5960-1-42
    • (2013) Acta Neuropathol. Commun , vol.1 , pp. 42
    • Freischmidt, A.1    Müller, K.2    Ludolph, A.C.3    Weishaupt, J.H.4
  • 27
    • 50249173450 scopus 로고    scopus 로고
    • MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators
    • Gabriely, G., Wurdinger, T., Kesari, S., Esau, C. C., Burchard, J., Linsley, P. S., et al. (2008). MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators. Mol. Cell. Biol. 28, 5369-5380. doi: 10.1128/MCB.00479-08
    • (2008) Mol. Cell. Biol , vol.28 , pp. 5369-5380
    • Gabriely, G.1    Wurdinger, T.2    Kesari, S.3    Esau, C.C.4    Burchard, J.5    Linsley, P.S.6
  • 28
  • 29
  • 30
    • 79957842166 scopus 로고    scopus 로고
    • Computational methods for transcriptome annotation and quantification using RNA-seq
    • Garber, M., Grabherr, M. G., Guttman, M., and Trapnell, C. (2011). Computational methods for transcriptome annotation and quantification using RNA-seq. Nat. Methods 8, 469-477. doi: 10.1038/nmeth.1613
    • (2011) Nat. Methods , vol.8 , pp. 469-477
    • Garber, M.1    Grabherr, M.G.2    Guttman, M.3    Trapnell, C.4
  • 31
    • 79960555311 scopus 로고    scopus 로고
    • Cerebrospinal fluid biomarkers for Alzheimer's disease: the present and the future
    • Ghidoni, R., Benussi, L., Paterlini, A., Albertini, V., Binetti, G., and Emanuele, E. (2011). Cerebrospinal fluid biomarkers for Alzheimer's disease: the present and the future. Neurodegener. Dis. 8, 413-420. doi: 10.1159/000327756
    • (2011) Neurodegener. Dis , vol.8 , pp. 413-420
    • Ghidoni, R.1    Benussi, L.2    Paterlini, A.3    Albertini, V.4    Binetti, G.5    Emanuele, E.6
  • 32
    • 77955719235 scopus 로고    scopus 로고
    • MiRNA-196 is upregulated in glioblastoma but not in anaplastic astrocytoma and has prognostic significance
    • Guan, Y., Mizoguchi, M., Yoshimoto, K., Hata, N., Shono, T., Suzuki, S. O., et al. (2010). MiRNA-196 is upregulated in glioblastoma but not in anaplastic astrocytoma and has prognostic significance. Clin. Cancer Res. 16, 4289-4297. doi: 10.1158/1078-0432.CCR-10-0207
    • (2010) Clin. Cancer Res , vol.16 , pp. 4289-4297
    • Guan, Y.1    Mizoguchi, M.2    Yoshimoto, K.3    Hata, N.4    Shono, T.5    Suzuki, S.O.6
  • 33
    • 84871297324 scopus 로고    scopus 로고
    • Regulated microRNAs in the CSF of patients with multiple sclerosis: a case-control study
    • Haghikia, A., Haghikia, A., Hellwig, K., Baraniskin, A., Holzmann, A., Decard, B. F., et al. (2012). Regulated microRNAs in the CSF of patients with multiple sclerosis: a case-control study. Neurology 79, 2166-2170. doi: 10.1212/WNL.0b013e3182759621
    • (2012) Neurology , vol.79 , pp. 2166-2170
    • Haghikia, A.1    Haghikia, A.2    Hellwig, K.3    Baraniskin, A.4    Holzmann, A.5    Decard, B.F.6
  • 34
    • 44049108170 scopus 로고    scopus 로고
    • Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression
    • Hébert, S. S., Horré, K., Nicolaï, L., Papadopoulou, A. S., Mandemakers, W., Silahtaroglu, A. N., et al. (2008). Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression. Proc. Natl. Acad. Sci. U.S.A. 105, 6415-6420. doi: 10.1073/pnas.0710263105
    • (2008) Proc. Natl. Acad. Sci. U.S.A , vol.105 , pp. 6415-6420
    • Hébert, S.S.1    Horré, K.2    Nicolaï, L.3    Papadopoulou, A.S.4    Mandemakers, W.5    Silahtaroglu, A.N.6
  • 35
    • 84940435386 scopus 로고    scopus 로고
    • Alzheimer's disease-Recent biomarker developments in relation to updated diagnostic criteria
    • Hoglund, K., Fourier, A., Perret-Liaudet, A., Zetterberg, H., Blennow, K., and Portelius, E. (2015). Alzheimer's disease-Recent biomarker developments in relation to updated diagnostic criteria. Clin. Chim. Acta 44, 9-8. doi: 10.1016/j.cca.2015.01.041
    • (2015) Clin. Chim. Acta , vol.44 , pp. 9-18
    • Hoglund, K.1    Fourier, A.2    Perret-Liaudet, A.3    Zetterberg, H.4    Blennow, K.5    Portelius, E.6
  • 36
    • 78650420189 scopus 로고    scopus 로고
    • Identifying and validating biomarkers for Alzheimer's disease
    • Humpel, C. (2011). Identifying and validating biomarkers for Alzheimer's disease. Trends Biotechnol. 29, 26-32. doi: 10.1016/j.tibtech.2010.09.007
    • (2011) Trends Biotechnol , vol.29 , pp. 26-32
    • Humpel, C.1
  • 37
    • 84924024740 scopus 로고    scopus 로고
    • Higher CSF interleukin-6 and CSF interleukin-8 in current depression in older women. Results from a population-based sample
    • Kern, S., Skoog, I., Borjesson-Hanson, A., Blennow, K., Zetterberg, H., Ostling, S., et al. (2014). Higher CSF interleukin-6 and CSF interleukin-8 in current depression in older women. Results from a population-based sample. Brain Behav. Immun. 4, 15-18. doi: 10.1016/j.bbi.2014.05.006
    • (2014) Brain Behav. Immun , vol.4 , pp. 15-18
    • Kern, S.1    Skoog, I.2    Borjesson-Hanson, A.3    Blennow, K.4    Zetterberg, H.5    Ostling, S.6
  • 38
    • 84893946623 scopus 로고    scopus 로고
    • MicroRNAs in plasma and cerebrospinal fluid as potential markers for Alzheimer's disease
    • Kiko, T., Nakagawa, K., Tsuduki, T., Furukawa, K., Arai, H., and Miyazawa, T. (2014). MicroRNAs in plasma and cerebrospinal fluid as potential markers for Alzheimer's disease. J. Alzheimers. Dis. 39, 253-259. doi: 10.3233/JAD-130932
    • (2014) J. Alzheimers. Dis , vol.39 , pp. 253-259
    • Kiko, T.1    Nakagawa, K.2    Tsuduki, T.3    Furukawa, K.4    Arai, H.5    Miyazawa, T.6
  • 39
    • 84901621290 scopus 로고    scopus 로고
    • Genetic markers for diagnosis and pathogenesis of Alzheimer's disease
    • Kim, D. H., Yeo, S. H., Park, J. M., Choi, J. Y., Lee, T. H., Park, S. Y., et al. (2014). Genetic markers for diagnosis and pathogenesis of Alzheimer's disease. Gene 545, 185-193. doi: 10.1016/j.gene.2014.05.031
    • (2014) Gene , vol.545 , pp. 185-193
    • Kim, D.H.1    Yeo, S.H.2    Park, J.M.3    Choi, J.Y.4    Lee, T.H.5    Park, S.Y.6
  • 40
    • 84896051978 scopus 로고    scopus 로고
    • When less is more-microRNAs and psychiatric disorders
    • Kolshus, E., Dalton, V. S., Ryan, K. M., and McLoughlin, D. M. (2014). When less is more-microRNAs and psychiatric disorders. Acta Psychiatr. Scand. 129, 241-256. doi: 10.1111/acps.12191
    • (2014) Acta Psychiatr. Scand , vol.129 , pp. 241-256
    • Kolshus, E.1    Dalton, V.S.2    Ryan, K.M.3    McLoughlin, D.M.4
  • 42
    • 84945471565 scopus 로고    scopus 로고
    • Cerebrospinal fluid levels of the synaptic protein neurogranin correlates with cognitive decline in prodromal Alzheimer's disease
    • Kvartsberg, H., Duits, F. H., Ingelsson, M., Andreasen, N., Öhrfelt, A., Andersson, K., et al. (2014). Cerebrospinal fluid levels of the synaptic protein neurogranin correlates with cognitive decline in prodromal Alzheimer's disease. Alzheimers Dement. 11, 1180-1190. doi: 10.1016/j.jalz.2014.10.009
    • (2014) Alzheimers Dement , vol.11 , pp. 1180-1190
    • Kvartsberg, H.1    Duits, F.H.2    Ingelsson, M.3    Andreasen, N.4    Öhrfelt, A.5    Andersson, K.6
  • 43
    • 84861577379 scopus 로고    scopus 로고
    • An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration
    • Lehmann, S. M., Krüger, C., Park, B., Derkow, K., Rosenberger, K., Baumgart, J., et al. (2012). An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration. Nat. Neurosci. 15, 827-835. doi: 10.1038/nn.3113
    • (2012) Nat. Neurosci , vol.15 , pp. 827-835
    • Lehmann, S.M.1    Krüger, C.2    Park, B.3    Derkow, K.4    Rosenberger, K.5    Baumgart, J.6
  • 44
    • 84884855701 scopus 로고    scopus 로고
    • High serum interleukin-6 level is associated with increased risk of delirium in elderly patients after noncardiac surgery: a prospective cohort study
    • Liu, P., Li, Y. W., Wang, X. S., Zou, X., Zhang, D. Z., Wang, D. X., et al. (2013). High serum interleukin-6 level is associated with increased risk of delirium in elderly patients after noncardiac surgery: a prospective cohort study. Chin. Med. J. 126, 3621-3627.
    • (2013) Chin. Med. J , vol.126 , pp. 3621-3627
    • Liu, P.1    Li, Y.W.2    Wang, X.S.3    Zou, X.4    Zhang, D.Z.5    Wang, D.X.6
  • 45
    • 84922029176 scopus 로고    scopus 로고
    • CTGF increases vascular endothelial growth factor-dependent angiogenesis in human synovial fibroblasts by increasing miR-210 expression
    • Liu, S. C., Chuang, S. M., Hsu, C. J., Tsai, C. H., Wang, S. W., and Tang, C. H. (2014). CTGF increases vascular endothelial growth factor-dependent angiogenesis in human synovial fibroblasts by increasing miR-210 expression. Cell Death Dis. 5:e1485. doi: 10.1038/cddis.2014.453
    • (2014) Cell Death Dis , vol.5
    • Liu, S.C.1    Chuang, S.M.2    Hsu, C.J.3    Tsai, C.H.4    Wang, S.W.5    Tang, C.H.6
  • 46
    • 84901979336 scopus 로고    scopus 로고
    • Cerebrospinal fluid and serum cytokine profiling to detect immune control of infectious and inflammatory neurological and psychiatric diseases
    • Maxeiner, H. G., Marion Schneider, E., Kurfiss, S. T., Brettschneider, J., Tumani, H., and Bechter, K. (2014). Cerebrospinal fluid and serum cytokine profiling to detect immune control of infectious and inflammatory neurological and psychiatric diseases. Cytokine 69, 62-67. doi: 10.1016/j.cyto.2014.05.008
    • (2014) Cytokine , vol.69 , pp. 62-67
    • Maxeiner, H.G.1    Marion Schneider, E.2    Kurfiss, S.T.3    Brettschneider, J.4    Tumani, H.5    Bechter, K.6
  • 47
    • 77956339881 scopus 로고    scopus 로고
    • OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma
    • Medina, P. P., Nolde, M., and Slack, F. J. (2010). OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma. Nature 467, 86-90. doi: 10.1038/nature09284
    • (2010) Nature , vol.467 , pp. 86-90
    • Medina, P.P.1    Nolde, M.2    Slack, F.J.3
  • 48
    • 78149407836 scopus 로고    scopus 로고
    • Normalization strategies for microRNA profiling experiments: a 'normal' way to a hidden layer of complexity?
    • Meyer, S. U., Pfaffl, M. W., and Ulbrich, S. E. (2010). Normalization strategies for microRNA profiling experiments: a 'normal' way to a hidden layer of complexity? Biotechnol. Lett. 32, 1777-1788. doi: 10.1007/s10529-010-0380-z
    • (2010) Biotechnol. Lett , vol.32 , pp. 1777-1788
    • Meyer, S.U.1    Pfaffl, M.W.2    Ulbrich, S.E.3
  • 49
    • 84928138931 scopus 로고    scopus 로고
    • MicroRNA-29a is a candidate biomarker for Alzheimer's disease in cell-free cerebrospinal fluid
    • [Epub ahead of print]
    • Müller, M., Jäkel, L., Bruinsma, I. B., Claassen, J. A., Kuiperij, H. B., and Verbeek, M. M. (2015). MicroRNA-29a is a candidate biomarker for Alzheimer's disease in cell-free cerebrospinal fluid. Mol. Neurobiol. doi: 10.1007/s12035-015-9156-8. [Epub ahead of print].
    • (2015) Mol. Neurobiol
    • Müller, M.1    Jäkel, L.2    Bruinsma, I.B.3    Claassen, J.A.4    Kuiperij, H.B.5    Verbeek, M.M.6
  • 50
    • 84886652538 scopus 로고    scopus 로고
    • Genome-wide expression profiling of human lymphoblastoid cell lines implicates integrin beta-3 in the mode of action of antidepressants
    • Oved, K., Morag, A., Pasmanik-Chor, M., Rehavi, M., Shomron, N., and Gurwitz, D. (2013). Genome-wide expression profiling of human lymphoblastoid cell lines implicates integrin beta-3 in the mode of action of antidepressants. Transl. Psychiatry 3:e313. doi: 10.1038/tp.2013.86
    • (2013) Transl. Psychiatry , vol.3
    • Oved, K.1    Morag, A.2    Pasmanik-Chor, M.3    Rehavi, M.4    Shomron, N.5    Gurwitz, D.6
  • 52
    • 84880341728 scopus 로고    scopus 로고
    • More than cell dust: microparticles isolated from cerebrospinal fluid of brain injured patients are messengers carrying mRNAs, miRNAs, and proteins
    • Patz, S., Trattnig, C., Grunbacher, G., Ebner, B., Gülly, C., Novak, A., et al. (2013). More than cell dust: microparticles isolated from cerebrospinal fluid of brain injured patients are messengers carrying mRNAs, miRNAs, and proteins. J. Neurotrauma 30, 1232-1242. doi: 10.1089/neu.2012.2596
    • (2013) J. Neurotrauma , vol.30 , pp. 1232-1242
    • Patz, S.1    Trattnig, C.2    Grunbacher, G.3    Ebner, B.4    Gülly, C.5    Novak, A.6
  • 53
    • 28544436950 scopus 로고    scopus 로고
    • Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria."
    • Polman, C. H., Reingold, S. C., Edan, G., Filippi, M., Hartung, H. P., Kappos, L., et al. (2005). Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria." Ann. Neurol. 58, 840-846. doi: 10.1002/ana.20703
    • (2005) Ann. Neurol , vol.58 , pp. 840-846
    • Polman, C.H.1    Reingold, S.C.2    Edan, G.3    Filippi, M.4    Hartung, H.P.5    Kappos, L.6
  • 54
    • 84859892863 scopus 로고    scopus 로고
    • MicroRNA profiling: approaches and considerations
    • Pritchard, C. C., Cheng, H. H., and Tewari, M. (2012). MicroRNA profiling: approaches and considerations. Nat. Rev. Genet. 13, 358-369. doi: 10.1038/nrg3198
    • (2012) Nat. Rev. Genet , vol.13 , pp. 358-369
    • Pritchard, C.C.1    Cheng, H.H.2    Tewari, M.3
  • 55
    • 84898657736 scopus 로고    scopus 로고
    • Cerebrospinal fluid biomarker and brain biopsy findings in idiopathic normal pressure hydrocephalus
    • Pyykö, O., Lumela, M., Rummukainen, J., Nerg, O., Seppälä, T. T., Herukka, S., et al. (2014). Cerebrospinal fluid biomarker and brain biopsy findings in idiopathic normal pressure hydrocephalus. PLoS ONE 9:e91974. doi: 10.1371/journal.pone.0091974
    • (2014) PLoS ONE , vol.9
    • Pyykö, O.1    Lumela, M.2    Rummukainen, J.3    Nerg, O.4    Seppälä, T.T.5    Herukka, S.6
  • 56
    • 84921027062 scopus 로고    scopus 로고
    • Identification of microRNAs as novel biomarkers for glioma detection: a meta-analysis based on 11 articles
    • Qu, S., Guan, J., and Liu, Y. (2015). Identification of microRNAs as novel biomarkers for glioma detection: a meta-analysis based on 11 articles. J. Neurol. Sci. 348, 181-187. doi: 10.1016/j.jns.2014.11.036
    • (2015) J. Neurol. Sci , vol.348 , pp. 181-187
    • Qu, S.1    Guan, J.2    Liu, Y.3
  • 57
    • 78149410101 scopus 로고    scopus 로고
    • MIR152, MIR200B, and MIR338, human positional and functional neuroblastoma candidates, are involved in neuroblast differentiation and apoptosis
    • Ragusa, M., Majorana, A., Banelli, B., Barbagallo, D., Statello, L., Casciano, I., et al. (2010). MIR152, MIR200B, and MIR338, human positional and functional neuroblastoma candidates, are involved in neuroblast differentiation and apoptosis. J. Mol. Med. 88, 1041-1053. doi: 10.1007/s00109-010-0643-0
    • (2010) J. Mol. Med , vol.88 , pp. 1041-1053
    • Ragusa, M.1    Majorana, A.2    Banelli, B.3    Barbagallo, D.4    Statello, L.5    Casciano, I.6
  • 58
    • 84888631877 scopus 로고    scopus 로고
    • MicroRNAs as biomarkers for CNS disease
    • Rao, P., Benito, E., and Fischer, A. (2013). MicroRNAs as biomarkers for CNS disease. Front. Mol. Neurosci. 6:39. doi: 10.3389/fnmol.2013.00039
    • (2013) Front. Mol. Neurosci , vol.6 , pp. 39
    • Rao, P.1    Benito, E.2    Fischer, A.3
  • 59
    • 63949088182 scopus 로고    scopus 로고
    • Specific expression of miR-17-5p and miR-127 in testicular and central nervous system diffuse large B-cell lymphoma
    • Robertus, J. L., Harms, G., Blokzijl, T., Booman, M., de Jong, D., van Imhoff, G., et al. (2009). Specific expression of miR-17-5p and miR-127 in testicular and central nervous system diffuse large B-cell lymphoma. Mod. Pathol. 22, 547-555. doi: 10.1038/modpathol.2009.10
    • (2009) Mod. Pathol , vol.22 , pp. 547-555
    • Robertus, J.L.1    Harms, G.2    Blokzijl, T.3    Booman, M.4    de Jong, D.5    van Imhoff, G.6
  • 60
    • 84949827682 scopus 로고    scopus 로고
    • Benchmarking biomarker-based criteria for Alzheimer's disease: data from the Swedish Dementia Registry, SveDem
    • Rosén, C., Farahmand, B., Skillbäck, T., Nägga, K., Mattsson, N., Kilander, L., et al. (2015). Benchmarking biomarker-based criteria for Alzheimer's disease: data from the Swedish Dementia Registry, SveDem. Alzheimers Dement. 11, 1470-1479. doi: 10.1016/j.jalz.2015.04.007
    • (2015) Alzheimers Dement , vol.11 , pp. 1470-1479
    • Rosén, C.1    Farahmand, B.2    Skillbäck, T.3    Nägga, K.4    Mattsson, N.5    Kilander, L.6
  • 61
    • 84896705855 scopus 로고    scopus 로고
    • Biomarkers in autism spectrum disorder: the old and the new
    • Ruggeri, B., Sarkans, U., Schumann, G., and Persico, A. M. (2014). Biomarkers in autism spectrum disorder: the old and the new. Psychopharmacology 231, 1201-1216. doi: 10.1007/s00213-013-3290-7
    • (2014) Psychopharmacology , vol.231 , pp. 1201-1216
    • Ruggeri, B.1    Sarkans, U.2    Schumann, G.3    Persico, A.M.4
  • 62
    • 84892156798 scopus 로고    scopus 로고
    • Reduced expression of hsa-miR-27a-3p in CSF of patients with Alzheimer disease
    • Sala Frigerio, C., Lau, P., Salta, E., Tournoy, J., Bossers, K., Vandenberghe, R., et al. (2013). Reduced expression of hsa-miR-27a-3p in CSF of patients with Alzheimer disease. Neurology 81, 2103-2106. doi: 10.1212/01.wnl.0000437306.37850.22
    • (2013) Neurology , vol.81 , pp. 2103-2106
    • Sala Frigerio, C.1    Lau, P.2    Salta, E.3    Tournoy, J.4    Bossers, K.5    Vandenberghe, R.6
  • 63
    • 79959843370 scopus 로고    scopus 로고
    • MicroRNA-21 targets tumor suppressor genes ANP32A and SMARCA4
    • Schramedei, K., Mörbt, N., Pfeifer, G., Läuter, J., Rosolowski, M., Tomm, J. M., et al. (2011). MicroRNA-21 targets tumor suppressor genes ANP32A and SMARCA4. Oncogene 30, 2975-2985. doi: 10.1038/onc.2011.15
    • (2011) Oncogene , vol.30 , pp. 2975-2985
    • Schramedei, K.1    Mörbt, N.2    Pfeifer, G.3    Läuter, J.4    Rosolowski, M.5    Tomm, J.M.6
  • 64
    • 77955872780 scopus 로고    scopus 로고
    • CSF proteomic analysis in patients with normal pressure hydrocephalus selected for the shunt: CSF biomarkers of response to surgical treatment
    • Scollato, A., Terreni, A., Caldini, A., Salvadori, B., Gallina, P., Francese, S., et al. (2010). CSF proteomic analysis in patients with normal pressure hydrocephalus selected for the shunt: CSF biomarkers of response to surgical treatment. Neurol. Sci. 31, 283-291. doi: 10.1007/s10072-009-0181-0
    • (2010) Neurol. Sci , vol.31 , pp. 283-291
    • Scollato, A.1    Terreni, A.2    Caldini, A.3    Salvadori, B.4    Gallina, P.5    Francese, S.6
  • 65
    • 84885040378 scopus 로고    scopus 로고
    • Circulating cell-free microRNA as biomarkers for screening, diagnosis and monitoring of neurodegenerative diseases and other neurologic pathologies
    • Sheinerman, K. S., and Umansky, S. R. (2013). Circulating cell-free microRNA as biomarkers for screening, diagnosis and monitoring of neurodegenerative diseases and other neurologic pathologies. Front. Cell. Neurosci. 7:150. doi: 10.3389/fncel.2013.00150
    • (2013) Front. Cell. Neurosci , vol.7 , pp. 150
    • Sheinerman, K.S.1    Umansky, S.R.2
  • 66
    • 77952336221 scopus 로고    scopus 로고
    • Aberrant microRNA expression in the brains of neurodegenerative diseases: miR-29a decreased in Alzheimer disease brains targets neurone navigator 3
    • Shioya, M., Obayashi, S., Tabunoki, H., Arima, K., Saito, Y., Ishida, T., et al. (2010). Aberrant microRNA expression in the brains of neurodegenerative diseases: miR-29a decreased in Alzheimer disease brains targets neurone navigator 3. Neuropathol. Appl. Neurobiol. 36, 320-330. doi: 10.1111/j.1365-2990.2010.01076.x
    • (2010) Neuropathol. Appl. Neurobiol , vol.36 , pp. 320-330
    • Shioya, M.1    Obayashi, S.2    Tabunoki, H.3    Arima, K.4    Saito, Y.5    Ishida, T.6
  • 68
    • 20844441406 scopus 로고    scopus 로고
    • Decreased release of the angiogenic peptide vascular endothelial growth factor in Alzheimer's disease: recovering effect with insulin and DHEA sulfate
    • Solerte, S. B., Ferrari, E., Cuzzoni, G., Locatelli, E., Giustina, A., Zamboni, M., et al. (2005). Decreased release of the angiogenic peptide vascular endothelial growth factor in Alzheimer's disease: recovering effect with insulin and DHEA sulfate. Dement. Geriatr. Cogn. Disord. 19, 1-10. doi: 10.1159/000080963
    • (2005) Dement. Geriatr. Cogn. Disord , vol.19 , pp. 1-10
    • Solerte, S.B.1    Ferrari, E.2    Cuzzoni, G.3    Locatelli, E.4    Giustina, A.5    Zamboni, M.6
  • 69
    • 84936128760 scopus 로고    scopus 로고
    • miRNA expression profiles in cerebrospinal fluid and blood of patients with acute ischemic stroke
    • Sørensen, S., Nygaard, A.-B., Nielsen, M.-Y., Jensen, K., and Christensen, T. (2014). miRNA expression profiles in cerebrospinal fluid and blood of patients with acute ischemic stroke. Transl. Stroke Res. 5, 711-718. doi: 10.1007/s12975-014-0364-8
    • (2014) Transl. Stroke Res , vol.5 , pp. 711-718
    • Sørensen, S.1    Nygaard, A.-B.2    Nielsen, M.-Y.3    Jensen, K.4    Christensen, T.5
  • 70
    • 84929610425 scopus 로고    scopus 로고
    • The role of microRNAs as potential biomarkers in central nervous system disorders
    • Stoicea, N., Wilson, T., Chandrasekhar, K., and Bergese, S. D. (2013). The role of microRNAs as potential biomarkers in central nervous system disorders. Int. J. Clin. Anesthesiol. 1:1009. doi: 10.3389/fnmol.2013.00039
    • (2013) Int. J. Clin. Anesthesiol , vol.1 , pp. 1009
    • Stoicea, N.1    Wilson, T.2    Chandrasekhar, K.3    Bergese, S.D.4
  • 71
    • 84862192105 scopus 로고    scopus 로고
    • MicroRNAs in cerebrospinal fluid identify glioblastoma and metastatic brain cancers and reflect disease activity
    • Teplyuk, N. M., Mollenhauer, B., Gabriely, G., Giese, A., Kim, E., Smolsky, M., et al. (2012). MicroRNAs in cerebrospinal fluid identify glioblastoma and metastatic brain cancers and reflect disease activity. Neuro-oncology 14, 689-700. doi: 10.1093/neuonc/nos074
    • (2012) Neuro-oncology , vol.14 , pp. 689-700
    • Teplyuk, N.M.1    Mollenhauer, B.2    Gabriely, G.3    Giese, A.4    Kim, E.5    Smolsky, M.6
  • 72
    • 84962595884 scopus 로고    scopus 로고
    • [cited 2015 October 16, 2015]
    • The ALS Association. (2015). Symptoms and Diagnosis: The ALS Association; 2015 [cited 2015 October 16, 2015]. Available online at: http://www.alsa.org/about-als/symptoms.html
    • (2015) Symptoms and Diagnosis: The ALS Association; 2015
  • 73
    • 84855164212 scopus 로고    scopus 로고
    • Biomarkers associated with delirium in critically ill patients and their relation with long-term subjective cognitive dysfunction; indications for different pathways governing delirium in inflamed and noninflamed patients
    • van den Boogaard, M., Kox, M., Quinn, K. L., van Achterberg, T., van der Hoeven, J. G., Schoonhoven, L., et al. (2011). Biomarkers associated with delirium in critically ill patients and their relation with long-term subjective cognitive dysfunction; indications for different pathways governing delirium in inflamed and noninflamed patients. Crit Care 15, R297. doi: 10.1186/cc10598
    • (2011) Crit Care , vol.15
    • van den Boogaard, M.1    Kox, M.2    Quinn, K.L.3    van Achterberg, T.4    van der Hoeven, J.G.5    Schoonhoven, L.6
  • 76
    • 84928891380 scopus 로고    scopus 로고
    • Identification of differential MicroRNAs in cerebrospinal fluid and serum of patients with major depressive disorder
    • Wan, Y., Liu, Y., Wang, X., Wu, J., Liu, K., Zhou, J., et al. (2015). Identification of differential MicroRNAs in cerebrospinal fluid and serum of patients with major depressive disorder. PLoS ONE 10:e0121975. doi: 10.1371/journal.pone.0121975
    • (2015) PLoS ONE , vol.10
    • Wan, Y.1    Liu, Y.2    Wang, X.3    Wu, J.4    Liu, K.5    Zhou, J.6
  • 78
    • 84939897109 scopus 로고    scopus 로고
    • MicroRNAs as potential biomarkers for diagnosing cancers of central nervous system: a meta-analysis
    • Wei, D., Wan, Q., Li, L., Jin, H., Liu, Y., Wang, Y., et al. (2015). MicroRNAs as potential biomarkers for diagnosing cancers of central nervous system: a meta-analysis. Mol. Neurobiol. 51, 1452-1461. doi: 10.1007/s12035-014-8822-6
    • (2015) Mol. Neurobiol , vol.51 , pp. 1452-1461
    • Wei, D.1    Wan, Q.2    Li, L.3    Jin, H.4    Liu, Y.5    Wang, Y.6
  • 79
    • 34748837455 scopus 로고    scopus 로고
    • Systematic analysis of microRNA expression of RNA extracted from fresh frozen and formalin-fixed paraffin-embedded samples
    • Xi, Y., Nakajima, G., Gavin, E., Morris, C. G., Kudo, K., Hayashi, K., et al. (2007). Systematic analysis of microRNA expression of RNA extracted from fresh frozen and formalin-fixed paraffin-embedded samples. RNA 13, 1668-1674. doi: 10.1261/rna.642907
    • (2007) RNA , vol.13 , pp. 1668-1674
    • Xi, Y.1    Nakajima, G.2    Gavin, E.3    Morris, C.G.4    Kudo, K.5    Hayashi, K.6
  • 80
    • 84922041798 scopus 로고    scopus 로고
    • Quantification of microRNA-210 in the cerebrospinal fluid and serum: implications for Alzheimer's disease
    • Zhu, Y., Li, C., Sun, A., Wang, Y., and Zhou, S. (2015). Quantification of microRNA-210 in the cerebrospinal fluid and serum: implications for Alzheimer's disease. Exp. Ther. Med. 9, 1013-1017. doi: 10.3892/etm.2015.2179
    • (2015) Exp. Ther. Med , vol.9 , pp. 1013-1017
    • Zhu, Y.1    Li, C.2    Sun, A.3    Wang, Y.4    Zhou, S.5
  • 81
    • 34247343262 scopus 로고    scopus 로고
    • Microvascular injury and blood-brain barrier leakage in Alzheimer's disease
    • Zipser, B. D., Johanson, C. E., Gonzalez, L., Berzin, T. M., Tavares, R., Hulette, C. M., et al. (2007). Microvascular injury and blood-brain barrier leakage in Alzheimer's disease. Neurobiol. Aging. 28, 977-986. doi: 10.1016/j.neurobiolaging.2006.05.016
    • (2007) Neurobiol. Aging , vol.28 , pp. 977-986
    • Zipser, B.D.1    Johanson, C.E.2    Gonzalez, L.3    Berzin, T.M.4    Tavares, R.5    Hulette, C.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.