miR-338-3p is over-expressed in blood, CFS, serum and spinal cord from sporadic amyotrophic lateral sclerosis patients

Neurogenetics

Volumn 15, Issue 4, 2014, Pages 243-253

  De Felice, Bruna ^a   Annunziata, Anna ^b   Fiorentino, Giuseppe ^b   Borra, Marco ^c   Biffali, Elio ^c   Coppola, Cinzia ^a,d   Cotrufo, Roberto ^a,d   Brettschneider, Johannes ^e   Giordana, Maria Luisa ^f   Dalmay, Tamas ^g   Wheeler, Guy ^g   D’Alessandro, Raffaella ^a  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

^b MONALDI HOSPITAL   (Italy)

^c STAZIONE ZOOLOGICA ANTON DOHRN   (Italy)

^d Regional Interuniversity Center for Research in Neuroscience (CIRN) Naples   (Italy)

^e UNIVERSITY OF ULM   (Germany)

^f UNIVERSITY OF TURIN   (Italy)

^g UNIVERSITY OF EAST ANGLIA   (United Kingdom)

Author keywords

CSF; Leukocytes; MicroRNAs; Real time PCR; sALS; Spinal cord

Indexed keywords

BIOLOGICAL MARKER; MICRORNA; MICRORNA 338 3P; UNCLASSIFIED DRUG; MIRN338 MICRORNA, HUMAN;

ADULT; AGED; ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BLOOD; BRAIN DYSFUNCTION; CEREBROSPINAL FLUID; COMPARATIVE STUDY; CONTROLLED STUDY; EARLY DIAGNOSIS; FEMALE; GENE OVEREXPRESSION; GRAY MATTER; HUMAN; HUNTINGTON CHOREA; IN SITU HYBRIDIZATION; LEUKOCYTE; MAJOR CLINICAL STUDY; MALE; PARKINSON DISEASE; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION; RNA EXTRACTION; SPINAL CORD; UPREGULATION; DEGENERATIVE DISEASE; METABOLISM; MIDDLE AGED;

AGED; AMYOTROPHIC LATERAL SCLEROSIS; FEMALE; HUMANS; MALE; MICRORNAS; MIDDLE AGED; NEURODEGENERATIVE DISEASES; SPINAL CORD; UP-REGULATION;

EID: 84919475780     PISSN: 13646745     EISSN: 13646753     Source Type: Journal    
DOI: 10.1007/s10048-014-0420-2     Document Type: Article

References (44)

1. Lagier-Tourenne C, Polymenidou M, Cleveland DW (2010) TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration. Hum Mol Genet 15:R46–R64
2. DeJesus-Hernandez M, Mackenzie IR, Boeve BF et al (2011) Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS. Neuron 72:245–256
3. Renton AE, Majounie E, Waite A et al (2011) A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD. Neuron 72:257–268
4. Bartel DP (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116:281–297
5. Nelson PT, Wang WX, Rajeev BW (2008) MicroRNAs (miRNAs) in neurodegenerative diseases. Brain Pathol 18:130–138
6. St Laurent G 3rd, Wahlestedt C (2007) Noncoding RNAs: couplers of analog and digital information in nervous system function? Trends Neurosci 30:612–621
7. Kocerha J, Kauppinen S, Wahlestedt C (2009) microRNAs in CNS disorders. Neuromolecular Med 11:162–172
8. Wang WX, Rajeev BW, Stromberg AJ, Ren N, Tang G et al (2008) The expression of microRNA miR-107 decreases early in Alzheimer’s disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1. J Neurosci 28:1213–1223
9. Weinberg MS, Wood MJA (2009) Short non-coding RNA biology and neurodegenerative disorders: novel disease targets and therapeutics. Hum Mol Genet 18:27–39
10. Sethi P, Lukiw WJ (2009) Micro-RNA abundance and stability in human brain: specific alterations in Alzheimer’s disease temporal lobe neocortex. Neurosci Lett 459:100–104
11. Freischmidt A, Müller K, Ludolph AC, Weishaupt JH (2013) Systemic dysregulation of TDP-43 binding microRNAs in amyotrophic lateral sclerosis. Acta Neuropathol Commun 1:42–51
12. Russell AP, Wada S, Vergani L, Hock MB, Lamon S, Léger B, Ushida T, Cartoni R, Wadley GD, Hespel P, Kralli A, Soraru G, Angelini C, Akimoto T (2012) Disruption of skeletal muscle mitochondrial network genes and miRNAs in amyotrophic lateral sclerosis. Neurobiol Dis 4:107–117
13. Bruneteau G, Simonet T, Bauché S, Mandjee N, Malfatti E, Girard E, Tanguy ML, Behin A, Khiami F, Sariali E, Hell-Remy C, Salachas F, Pradat PF, Fournier E, Lacomblez L, Koenig J, Romero NB, Fontaine B, Meininger V, Schaeffer L, Hantaï D (2013) Muscle histone deacetylase 4 upregulation in amyotrophic lateral sclerosis: potential role in reinnervation ability and disease progression. Brain 136:2359–2368
14. Borovecki F, Lovrecic L, Zhou J, Jeong H, Then F et al (2005) Genome-wide expression profiling of human blood reveals biomarkers for Huntington’s disease. Proc Natl Acad Sci U S A 102:11023–11028
15. Maes OC, Xu S, Yu B, Chertkow HM, Wang E et al (2007) Transcriptional profiling of Alzheimer blood mononuclear cells by microarray. Neurobiol Aging 28:1795–1809
16. Nishimura Y, Martin CL, Vazquez-Lopez A, Spence SJ, Alvarez-Retuerto AI et al (2007) Genome-wide expression profiling of lymphoblastoid cell lines distinguishes different forms of autism and reveals shared pathways. Hum Mol Genet 16:1682–1698
17. De Felice B, Guida M, Guida M, Coppola C, De Mieri G et al (2012) A miRNA signature in leukocytes from sporadic amyotrophic lateral sclerosis. Gene 508(1):35–40
18. Fleige S, Pfaffl MW (2006) RNA integrity and the effect on the real-time qRT-PCR performance. Mol Aspects Med 27:126–139
19. Bissels U, Wild S, Tomiuk S, Holste A, Hafner M et al (2009) Absolute quantification of microRNAs by using a universal reference. RNA 15:2375–2384
20. Chen X, Liang H, Guan D, Wang C, Hu X, Cui L, Chen S, Zhang C, Zhang J, Zen K, Zhang CY (2013) A combination of Let-7d, Let-7g and Let-7i serves as a stable reference for normalization of serum microRNAs. PLoS One 8(11):e79652. doi:10.1371/journal.pone.0079652
21. Baraniskin A, Kuhnhenn J, Schlegel U, Chan A, Deckert M, Gold R, Maghnouj A, Zöllner H, Reinacher-Schick A, Schmiegel W, Hahn SA, Schroers R (2011) Identification of microRNAs in the cerebrospinal fluid as marker for primary diffuse large B-cell lymphoma of the central nervous system. Blood 117:3140–3146
22. Miska EA, Alvarez-Saavedra E, Townsend M, Yoshii A, Sestan N et al (2004) Microarray analysis of microRNA expression in the developing mammalian brain. Genome Biol 5:R68
23. Schaefer A, O’Carroll D, Tan CL, Hillman D, Sugimori M et al (2007) Cerebellar neurodegeneration in the absence of microRNAs. J Exp Med 204:1553–1558
24. Hebert SS, De Strooper B (2009) Alterations of the microRNA network cause neurodegenerative disease. Trends Neurosci 32:199–206
25. Li D, Chen P, Li XY, Zhang LY, Xiong W et al (2011) Grade-specific expression profiles of miRNAs/mRNAs and docking study in human grade I-III astrocytomas. Omics 15(10):673–682
26. Nan Y, Han L, Zhang A, Wang G, Jia Z et al (2010) MiRNA-451 plays a role as tumor suppressor in human glioma cells. Brain Res 1359:14–21
27. Te JL, Dozmorov IM, Guthridge JM, Nguyen KL, Cavett JW et al (2010) Identification of unique microRNA signature associated with lupus nephritis. PLoS One 5(5):e10344
28. Santarelli DM, Beveridge NJ, Tooney PA, Cairns MJ (2011) Upregulation of dicer and microRNA expression in the dorsolateral prefrontal cortex Brodmann area 46 in schizophrenia. Biol Psychiatry 69:180–187
29. Malzkorn B, Wolter M, Liesenberg F, Grzendowski M, Stühler K et al (2010) Identification and functional characterization of microRNAs involved in the malignant progression of gliomas. Brain Pathol 20:539–550
30. Lillo P, Mioshi E, Burrell JR, Kiernan MC, Hodges JR et al (2012) Grey and white matter changes across the amyotrophic lateral sclerosis-frontotemporal dementia continuum. PLoS One 7(8):e43993
31. Bede P, Bokde A, Elamin M, Byrne S, McLaughlin RL et al (2013) Grey matter correlates of clinical variables in amyotrophic lateral sclerosis (ALS): a neuroimaging study of ALS motor phenotype heterogeneity and cortical focality. J Neurol Neurosurg Psychiatry 84(7):766–773
32. Malessa S, Leigh PN, Bertel O, Sluga E, Hornykiewicz O (1991) Amyotrophic lateral sclerosis: glutamate dehydrogenase and transmitter amino acids in the spinal cord. J Neurol Neurosurg Psychiatry 54(11):984–988
33. Tomiyama M, Kimura T, Maeda T, Tanaka H, Furusawa K et al (2001) Expression of metabotropic glutamate receptor mRNAs in the human spinal cord: implications for selective vulnerability of spinal motor neurons in amyotrophic lateral sclerosis. J Neurol Sci 189(1–2):65–69
34. Kos A, Olde Loohuis NF, Wieczorek ML, Glennon JC, Martens GJ, Kolk SM, Aschrafi A (2012) A potential regulatory role for intronic microRNA-338-3p for its host gene encoding apoptosis-associated tyrosine kinase. PLoS One 7(2):e31022. doi:10.1371/journal.pone.0031022
35. Tomomura M, Fernandez-Gonzales A, Yano R, Yuzaki M (2001) Characterization of the apoptosis-associated tyrosine kinase (AATYK) expressed in the CNS. Oncogene 20:1022–1032
36. Ragusa M, Majorana A, Banelli B, Barbagallo D, Statello L et al (2010) MIR152, MIR200B, and MIR338, human positional and functional neuroblastoma candidates, are involved in neuroblast differentiation and apoptosis. J Mol Med (Berl) 88:1041–1053
37. Zhao X, He X, Han X, Yu Y, Ye F et al (2010) MicroRNA-mediated control of oligodendrocyte differentiation. Neuron 65:612–626
38. Aschrafi A, Natera-Naranjo O, Gioio AE, Kaplan BB (2010) Regulation of axonal trafficking of cytochrome c oxidase IV mRNA. Mol Cell Neurosci 43:422–430, 39
39. Natera-Naranjo O, Aschrafi A, Gioio AE, Kaplan BB (2010) Identification and quantitative analyses of microRNAs located in the distal axons of sympathetic neurons. RNA 16:1516–1529
40. Chen X, Pan M, Han L, Lu H, Hao X, Dong Q (2013) miR-338-3p suppresses neuroblastoma proliferation, invasion and migration through targeting PREX2a. FEBS Lett 587:3729–3737
41. Dorval V, Nelson PT, Hébert SS (2013) Circulating microRNAs in Alzheimer’s disease: the search for novel biomarkers. Front Mol Neurosci 6:24
42. Soreq L, Salomonis N, Bronstein M, Greenberg DS, Israel Z et al (2013) Small RNA sequencing-microarray analyses in Parkinson leukocytes reveal deep brain stimulation-induced splicing changes that classify brain region transcriptomes. Front Mol Neurosci 6:10
43. Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N et al (2007) A mammalian microRNA expression atlas based on small RNA library sequencing. Cell 129:1401–1414
44. Hebert SS, Wang WX, Zhu Q, Nelson PT (2013) A study of small RNAs from cerebral neocortex of pathology-verified Alzheimer’s disease, dementia with Lewy bodies, hippocampal sclerosis, frontotemporal lobar dementia, and non-demented human controls. J Alzheimers Dis 35:335–348