메뉴 건너뛰기




Volumn 3, Issue , 2013, Pages

Genome-wide expression profiling of human lymphoblastoid cell lines implicates integrin beta-3 in the mode of action of antidepressants

Author keywords

CD61; GPIIIa; Human lymphoblastoid cell lines; ITGB3; MicroRNAs; Serotonin transporter; SSRI antidepressants

Indexed keywords

BETA3 INTEGRIN; BINDING PROTEIN; CHL1 PROTEIN; MICRORNA 221; MICRORNA 222; PAROXETINE; SEROTONIN RECEPTOR; SEROTONIN TRANSPORTER; SEROTONIN UPTAKE INHIBITOR; UNCLASSIFIED DRUG; CELL ADHESION MOLECULE; CHL1 PROTEIN, HUMAN; ITGB3 PROTEIN, HUMAN; MESSENGER RNA; MICRORNA; MIRN221 MICRORNA, HUMAN; MIRN222 MICRORNA, HUMAN; SLC6A4 PROTEIN, HUMAN;

EID: 84886652538     PISSN: None     EISSN: 21583188     Source Type: Journal    
DOI: 10.1038/tp.2013.86     Document Type: Article
Times cited : (59)

References (51)
  • 1
    • 79951915363 scopus 로고    scopus 로고
    • A review of the current guidelines for depression treatment
    • Gelenberg AJ. A review of the current guidelines for depression treatment. J Clin Psychiatry 2010; 71: e15.
    • (2010) J Clin Psychiatry , vol.71
    • Gelenberg, A.J.1
  • 2
    • 78751517912 scopus 로고    scopus 로고
    • Antidepressants for the treatment of depression in palliative care: Systematic review and meta-analysis
    • Rayner L, Price A, Evans A, Valsraj K, Hotopf M, Higginson IJ. Antidepressants for the treatment of depression in palliative care: systematic review and meta-analysis. Palliat Med 2011; 25: 36-51.
    • (2011) Palliat Med , vol.25 , pp. 36-51
    • Rayner, L.1    Price, A.2    Evans, A.3    Valsraj, K.4    Hotopf, M.5    Higginson, I.J.6
  • 5
    • 0025164877 scopus 로고
    • Lithium and serotonin function: Implications for the serotonin hypothesis of depression
    • Price LH, Charney DS, Delgado PL, Heninger GR. Lithium and serotonin function: implications for the serotonin hypothesis of depression. Psychopharmacology (Berl) 1990; 100: 3-12.
    • (1990) Psychopharmacology (Berl) , vol.100 , pp. 3-12
    • Price, L.H.1    Charney, D.S.2    Delgado, P.L.3    Heninger, G.R.4
  • 6
    • 80855123608 scopus 로고    scopus 로고
    • Depression, antidepressants, and neurogenesis: A critical reappraisal
    • Hanson ND, Owens MJ, Nemeroff CB. Depression, antidepressants, and neurogenesis: a critical reappraisal. Neuropsychopharmacology 2011; 36: 2589-60.
    • (2011) Neuropsychopharmacology , vol.36 , pp. 2589-2660
    • Hanson, N.D.1    Owens, M.J.2    Nemeroff, C.B.3
  • 7
    • 84867213664 scopus 로고    scopus 로고
    • Depression and hippocampal neurogenesis: A road to remission?
    • Eisch AJ, Petrik D. Depression and hippocampal neurogenesis: a road to remission? Science 2012; 338: 72-75.
    • (2012) Science , vol.338 , pp. 72-75
    • Eisch, A.J.1    Petrik, D.2
  • 8
    • 84891717570 scopus 로고    scopus 로고
    • Novel insights into depression and antidepressants: A synergy between synaptogenesis and neurogenesis?
    • Bambico FR, Belzung C.. Novel insights into depression and antidepressants: a synergy between synaptogenesis and neurogenesis? Curr Top Behav Neurosci 2012; 15: 243-291.
    • (2012) Curr Top Behav Neurosci , vol.15 , pp. 243-291
    • Bambico, F.R.1    Belzung, C.2
  • 10
    • 46949104983 scopus 로고    scopus 로고
    • Even neural stem cells get the blues: Evidence for a molecular link between modulation of adult neurogenesis and depression
    • Thomas RM, Peterson DA. Even neural stem cells get the blues: evidence for a molecular link between modulation of adult neurogenesis and depression. Gene Expr 2008; 14: 183-193.
    • (2008) Gene Expr , vol.14 , pp. 183-193
    • Thomas, R.M.1    Peterson, D.A.2
  • 11
    • 84864759986 scopus 로고    scopus 로고
    • Neuroplastic changes in depression: A role for the immune system
    • Eyre H, Baune BT. Neuroplastic changes in depression: a role for the immune system. Psychoneuroendocrinology 2012; 37: 1397-1416.
    • (2012) Psychoneuroendocrinology , vol.37 , pp. 1397-1416
    • Eyre, H.1    Baune, B.T.2
  • 12
    • 84856196202 scopus 로고    scopus 로고
    • Depression, stress, epilepsy and adult neurogenesis
    • Danzer SC. Depression, stress, epilepsy and adult neurogenesis. Exp Neurol. 2012; 233: 22-32.
    • (2012) Exp Neurol. , vol.233 , pp. 22-32
    • Danzer, S.C.1
  • 13
  • 14
    • 0036703989 scopus 로고    scopus 로고
    • Serotonin clearance in vivo is altered to a greater extent by antidepressant-induced downregulation of the serotonin transporter than by acute blockade of this transporter
    • Benmansour S, Owens WA, Cecchi M, Morilak DA, Frazer A. Serotonin clearance in vivo is altered to a greater extent by antidepressant-induced downregulation of the serotonin transporter than by acute blockade of this transporter. J Neurosci 2002; 22: 6766-6772.
    • (2002) J Neurosci , vol.22 , pp. 6766-6772
    • Benmansour, S.1    Owens, W.A.2    Cecchi, M.3    Morilak, D.A.4    Frazer, A.5
  • 16
    • 34247137134 scopus 로고    scopus 로고
    • Imaging the serotonin transporter during major depressive disorder and antidepressant treatment
    • Meyer JH. Imaging the serotonin transporter during major depressive disorder and antidepressant treatment. J Psychiatry Neurosci 2007; 32: 86-102.
    • (2007) J Psychiatry Neurosci , vol.32 , pp. 86-102
    • Meyer, J.H.1
  • 17
    • 77958022683 scopus 로고    scopus 로고
    • Development of effective PET and SPECT imaging agents for the serotonin transporter: Has a twenty-year journey reached its destination?
    • Huang Y, Zheng MQ, Gerdes JM. Development of effective PET and SPECT imaging agents for the serotonin transporter: has a twenty-year journey reached its destination? Curr Top Med Chem 2010; 10: 1499-1526.
    • (2010) Curr Top Med Chem , vol.10 , pp. 1499-1526
    • Huang, Y.1    Zheng, M.Q.2    Gerdes, J.M.3
  • 18
    • 84864245394 scopus 로고    scopus 로고
    • Effects of the antidepressant fluoxetine on the subcellular localization of 5-HT1A receptors and SERT
    • Descarries L, Riad M. Effects of the antidepressant fluoxetine on the subcellular localization of 5-HT1A receptors and SERT. Philos Trans R Soc Lond B Biol Sci 2012; 367: 2416-2425.
    • (2012) Philos Trans R Soc Lond B Biol Sci , vol.367 , pp. 2416-2425
    • Descarries, L.1    Riad, M.2
  • 19
    • 84856351442 scopus 로고    scopus 로고
    • Modeling depression in animal models
    • Overstreet DH. Modeling depression in animal models. Methods Mol Biol 2012; 829: 125-144.
    • (2012) Methods Mol Biol , vol.829 , pp. 125-144
    • Overstreet, D.H.1
  • 20
    • 84880075737 scopus 로고    scopus 로고
    • Animal models of depression vulnerability
    • Harro J. Animal models of depression vulnerability. Curr Top Behav Neurosci 2013; 14: 29-54.
    • (2013) Curr Top Behav Neurosci , vol.14 , pp. 29-54
    • Harro, J.1
  • 21
    • 65849518449 scopus 로고    scopus 로고
    • Utility of lymphoblastoid cell lines
    • Sie L, Loong S, Tan EK.. Utility of lymphoblastoid cell lines. J Neurosci Res 2009; 87: 1953-1959.
    • (2009) J Neurosci Res , vol.87 , pp. 1953-1959
    • Sie, L.1    Loong, S.2    Tan, E.K.3
  • 23
    • 83755207567 scopus 로고    scopus 로고
    • Lymphoblastoid cell lines in pharmacogenomic discovery and clinical translation
    • Wheeler HE, Dolan ME. Lymphoblastoid cell lines in pharmacogenomic discovery and clinical translation. Pharmacogenomics 2012; 13: 55-70.
    • (2012) Pharmacogenomics , vol.13 , pp. 55-70
    • Wheeler, H.E.1    Dolan, M.E.2
  • 24
    • 79951869835 scopus 로고    scopus 로고
    • Genome-wide expression profiling of human lymphoblastoid cell lines identifies CHL1 as a putative SSRI antidepressant response biomarker
    • Morag A, Pasmanik-Chor M, Oron-Karni V, Rehavi M, Stingl JC, Gurwitz D. Genome-wide expression profiling of human lymphoblastoid cell lines identifies CHL1 as a putative SSRI antidepressant response biomarker. Pharmacogenomics 2011; 12: 171-184.
    • (2011) Pharmacogenomics , vol.12 , pp. 171-184
    • Morag, A.1    Pasmanik-Chor, M.2    Oron-Karni, V.3    Rehavi, M.4    Stingl, J.C.5    Gurwitz, D.6
  • 25
    • 84865322046 scopus 로고    scopus 로고
    • Genome-wide miRNA expression profiling of human lymphoblastoid cell lines identifies tentative SSRI antidepressant response biomarkers
    • Oved K, Morag A, Pasmanik-Chor M, Oron-Karni V, Shomron N, Rehavi M, Stingl JC, Gurwitz D. Genome-wide miRNA expression profiling of human lymphoblastoid cell lines identifies tentative SSRI antidepressant response biomarkers. Pharmacogenomics 2012; 13: 1129-1139.
    • (2012) Pharmacogenomics , vol.13 , pp. 1129-1139
    • Oved, K.1    Morag, A.2    Pasmanik-Chor, M.3    Oron-Karni, V.4    Shomron, N.5    Rehavi, M.6    Stingl, J.C.7    Gurwitz, D.8
  • 26
    • 43249095051 scopus 로고    scopus 로고
    • Bergmann glia and the recognition molecule CHL1 organize GABAergic axons and direct innervation of Purkinje cell dendrites
    • Ango F, Wu C, Van der Want JJ, Wu P, Schachner M, Huang ZJ. Bergmann glia and the recognition molecule CHL1 organize GABAergic axons and direct innervation of Purkinje cell dendrites. PLoS Biol 2008; 6: e103.
    • (2008) PLoS Biol , vol.6
    • Ango, F.1    Wu, C.2    Van Der Want, J.J.3    Wu, P.4    Schachner, M.5    Huang, Z.J.6
  • 27
    • 38049051162 scopus 로고    scopus 로고
    • Neural recognition molecules CHL1 and NB-3 regulate apical dendrite orientation in the neocortex via PTP alpha
    • Ye H, Tan YL, Ponniah S, Takeda Y, Wang SQ, Schachner M et al. Neural recognition molecules CHL1 and NB-3 regulate apical dendrite orientation in the neocortex via PTP alpha. EMBO J 2008; 27: 188-200.
    • (2008) EMBO J , vol.27 , pp. 188-200
    • Ye, H.1    Tan, Y.L.2    Ponniah, S.3    Takeda, Y.4    Wang, S.Q.5    Schachner, M.6
  • 28
    • 84871790544 scopus 로고    scopus 로고
    • Lipid raft-dependent endocytosis of close homolog of adhesion molecule L1 (CHL1) promotes neuritogenesis
    • Tian N, Leshchyns'ka I, Welch JH, Diakowski W, Yang H, Schachner M, Sytnyk V. Lipid raft-dependent endocytosis of close homolog of adhesion molecule L1 (CHL1) promotes neuritogenesis. J Biol Chem 2012; 287: 44447-44463.
    • (2012) J Biol Chem , vol.287 , pp. 44447-44463
    • Tian, N.1    Leshchyns'Ka, I.2    Welch, J.H.3    Diakowski, W.4    Yang, H.5    Schachner, M.6    Sytnyk, V.7
  • 32
    • 70449728080 scopus 로고    scopus 로고
    • Differential involvement of beta3 integrin in pre- and postsynaptic forms of adaptation to chronic activity deprivation
    • Cingolani LA, Goda Y.. Differential involvement of beta3 integrin in pre- and postsynaptic forms of adaptation to chronic activity deprivation. Neuron Glia Biol 2008; 4: 179-187.
    • (2008) Neuron Glia Biol , vol.4 , pp. 179-187
    • Cingolani, L.A.1    Goda, Y.2
  • 33
    • 84856397822 scopus 로고    scopus 로고
    • β3 integrin interacts directly with GluA2 AMPA receptor subunit and regulates AMPA receptor expression in hippocampal neurons
    • Pozo K, Cingolani LA, Bassani S, Laurent F, Passafaro M, Goda Y. β3 integrin interacts directly with GluA2 AMPA receptor subunit and regulates AMPA receptor expression in hippocampal neurons. Proc Natl Acad Sci USA 2012; 109: 1323-1328.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 1323-1328
    • Pozo, K.1    Cingolani, L.A.2    Bassani, S.3    Laurent, F.4    Passafaro, M.5    Goda, Y.6
  • 34
    • 15944367439 scopus 로고    scopus 로고
    • Transcriptional profiling reveals evidence for signaling and oligodendroglial abnormalities in the temporal cortex from patients with major depressive disorder
    • Aston C, Jiang L, Sokolov BP. Transcriptional profiling reveals evidence for signaling and oligodendroglial abnormalities in the temporal cortex from patients with major depressive disorder. Mol Psychiatry 2005; 10: 309-322.
    • (2005) Mol Psychiatry , vol.10 , pp. 309-322
    • Aston, C.1    Jiang, L.2    Sokolov, B.P.3
  • 35
    • 70350528991 scopus 로고    scopus 로고
    • Tetraspanin12 regulates ADAM10-dependent cleavage of amyloid precursor protein
    • Xu D, Sharma C, Hemler ME. Tetraspanin12 regulates ADAM10-dependent cleavage of amyloid precursor protein. FASEB J 2009; 23: 3674-3681.
    • (2009) FASEB J , vol.23 , pp. 3674-3681
    • Xu, D.1    Sharma, C.2    Hemler, M.E.3
  • 36
    • 79959530983 scopus 로고    scopus 로고
    • Submicroscopic deletion in 7q31 encompassing CADPS2 and TSPAN12 in a child with autism spectrum disorder and PHPV
    • Okamoto N, Hatsukawa Y, Shimojima K, Yamamoto T. Submicroscopic deletion in 7q31 encompassing CADPS2 and TSPAN12 in a child with autism spectrum disorder and PHPV. Am J Med Genet A 2011; 155A: 1568-1573.
    • (2011) Am J Med Genet A , vol.155 A , pp. 1568-1573
    • Okamoto, N.1    Hatsukawa, Y.2    Shimojima, K.3    Yamamoto, T.4
  • 37
    • 0035252964 scopus 로고    scopus 로고
    • Murine homologs of deltex define a novel gene family involved in vertebrate Notch signaling and neurogenesis
    • Kishi N, Tang Z, Maeda Y, Hirai A, Mo R, Ito M et al. Murine homologs of deltex define a novel gene family involved in vertebrate Notch signaling and neurogenesis. Int J Dev Neurosci 2001; 19: 21-35.
    • (2001) Int J Dev Neurosci , vol.19 , pp. 21-35
    • Kishi, N.1    Tang, Z.2    Maeda, Y.3    Hirai, A.4    Mo, R.5    Ito, M.6
  • 38
    • 82855165029 scopus 로고    scopus 로고
    • Interaction between NF-kB signaling and Notch signaling in gliogenesis of mouse mesencephalic neural crest cells
    • Fujita K, Yasui S, Shinohara T, Ito K. Interaction between NF-kB signaling and Notch signaling in gliogenesis of mouse mesencephalic neural crest cells. Mech Dev 2011; 128: 496-509.
    • (2011) Mech Dev , vol.128 , pp. 496-509
    • Fujita, K.1    Yasui, S.2    Shinohara, T.3    Ito, K.4
  • 39
    • 65949109048 scopus 로고    scopus 로고
    • Profiling RNA interference (RNAi)-mediated toxicity in neural cultures for effective short interfering RNA design
    • Read ML, Mir S, Spice R, Seabright RJ, Suggate EL, Ahmed Z et al. Profiling RNA interference (RNAi)-mediated toxicity in neural cultures for effective short interfering RNA design. J Gene Med 2009; 11: 523-534.
    • (2009) J Gene Med , vol.11 , pp. 523-534
    • Read, M.L.1    Mir, S.2    Spice, R.3    Seabright, R.J.4    Suggate, E.L.5    Ahmed, Z.6
  • 40
    • 64949159019 scopus 로고    scopus 로고
    • Evidence for selective microRNAs and their effectors as common long-term targets for the actions of mood stabilizers
    • Zhou R, Yuan P, Wang Y, Hunsberger JG, Elkahloun A, Wei Y et al. Evidence for selective microRNAs and their effectors as common long-term targets for the actions of mood stabilizers. Neuropsychopharmacology 2009; 34: 1395-1405.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 1395-1405
    • Zhou, R.1    Yuan, P.2    Wang, Y.3    Hunsberger, J.G.4    Elkahloun, A.5    Wei, Y.6
  • 41
    • 11244328520 scopus 로고    scopus 로고
    • Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome
    • Horike S, Cai S, Miyano M, Cheng JF, Kohwi-Shigematsu T. Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome. Nat Genet 2005; 37: 31-40.
    • (2005) Nat Genet , vol.37 , pp. 31-40
    • Horike, S.1    Cai, S.2    Miyano, M.3    Cheng, J.F.4    Kohwi-Shigematsu, T.5
  • 42
    • 84862816686 scopus 로고    scopus 로고
    • Characterization of DNA methylation and its association with other biological systems in lymphoblastoid cell lines
    • Zhang Z, Liu J, Kaur M, Krantz ID. Characterization of DNA methylation and its association with other biological systems in lymphoblastoid cell lines. Genomics 2012; 99: 209-219.
    • (2012) Genomics , vol.99 , pp. 209-219
    • Zhang, Z.1    Liu, J.2    Kaur, M.3    Krantz, I.D.4
  • 43
    • 83855165213 scopus 로고    scopus 로고
    • Inverse correlation between clinical response to paroxetine and plasma drug concentration in patients with major depressive disorders
    • Yasui-Furukori N, Nakagami T, Kaneda A, Inoue Y, Suzuki A, Otani K, Kaneko S. Inverse correlation between clinical response to paroxetine and plasma drug concentration in patients with major depressive disorders. Hum Psychopharmacol 2011; 26: 602-608.
    • (2011) Hum Psychopharmacol , vol.26 , pp. 602-608
    • Yasui-Furukori, N.1    Nakagami, T.2    Kaneda, A.3    Inoue, Y.4    Suzuki, A.5    Otani, K.6    Kaneko, S.7
  • 44
    • 84870786995 scopus 로고    scopus 로고
    • Genome-wide transcriptomic variations of human lymphoblastoid cell lines: Insights from pairwise gene-expression correlations
    • Vincent M, Oved K, Morag A, Pasmanik-Chor M, Oron-Karni V, Shomron N, Gurwitz D. Genome-wide transcriptomic variations of human lymphoblastoid cell lines: insights from pairwise gene-expression correlations. Pharmacogenomics 2012; 13: 1893-1904.
    • (2012) Pharmacogenomics , vol.13 , pp. 1893-1904
    • Vincent, M.1    Oved, K.2    Morag, A.3    Pasmanik-Chor, M.4    Oron-Karni, V.5    Shomron, N.6    Gurwitz, D.7
  • 45
    • 41849117712 scopus 로고    scopus 로고
    • Interactions between integrin alphaIIbbeta3 and the serotonin transporter regulate serotonin transport and platelet aggregation in mice and humans
    • Carneiro AM, Cook EH, Murphy DL, Blakely RD. Interactions between integrin alphaIIbbeta3 and the serotonin transporter regulate serotonin transport and platelet aggregation in mice and humans. J Clin Invest 2008; 118: 1544-1552.
    • (2008) J Clin Invest , vol.118 , pp. 1544-1552
    • Carneiro, A.M.1    Cook, E.H.2    Murphy, D.L.3    Blakely, R.D.4
  • 46
    • 79951574616 scopus 로고    scopus 로고
    • Absence of preference for social novelty and increased grooming in integrin b3 knockout mice: Initial studies and future directions
    • Carter MD, Shah CR, Muller CL, Crawley JN, Carneiro AM, Veenstra-VanderWeele J. Absence of preference for social novelty and increased grooming in integrin b3 knockout mice: initial studies and future directions. Autism Res 2011; 4: 57-67.
    • (2011) Autism Res , vol.4 , pp. 57-67
    • Carter, M.D.1    Shah, C.R.2    Muller, C.L.3    Crawley, J.N.4    Carneiro, A.M.5    Veenstra-Vander Weele, J.6
  • 47
    • 84866842812 scopus 로고    scopus 로고
    • Neuroanatomical assessment of the integrin b3 mouse model related to autism and the serotonin system using high resolution MRI
    • Ellegood J, Henkelman RM, Lerch JP. Neuroanatomical assessment of the integrin b3 mouse model related to autism and the serotonin system using high resolution MRI. Front Psychiatry 2012; 3: 37.
    • (2012) Front Psychiatry , vol.3 , pp. 37
    • Ellegood, J.1    Henkelman, R.M.2    Lerch, J.P.3
  • 49
    • 7044222373 scopus 로고    scopus 로고
    • Close homolog of L1 modulates area-specific neuronal positioning and dendrite orientation in the cerebral cortex
    • Demyanenko GP, Schachner M, Anton E, Schmid R, Feng G, Sanes J, Maness PF. Close homolog of L1 modulates area-specific neuronal positioning and dendrite orientation in the cerebral cortex. Neuron 2004; 44: 423-437.
    • (2004) Neuron , vol.44 , pp. 423-437
    • Demyanenko, G.P.1    Schachner, M.2    Anton, E.3    Schmid, R.4    Feng, G.5    Sanes, J.6    Maness, P.F.7
  • 50
    • 38049184323 scopus 로고    scopus 로고
    • CHL1 promotes Sema3A-induced growth cone collapse and neurite elaboration through a motif required for recruitment of ERM proteins to the plasma membrane
    • Schlatter MC, Buhusi M, Wright AG, Maness PF. CHL1 promotes Sema3A-induced growth cone collapse and neurite elaboration through a motif required for recruitment of ERM proteins to the plasma membrane. J Neurochem 2008; 104: 731-744.
    • (2008) J Neurochem , vol.104 , pp. 731-744
    • Schlatter, M.C.1    Buhusi, M.2    Wright, A.G.3    Maness, P.F.4
  • 51
    • 84902515774 scopus 로고    scopus 로고
    • Serotonin transporter and integrin beta 3 genes interact to modulate serotonin uptake in mouse brain
    • advance online publication 28 September, doi:pii:S0197-0186(13)00 241-6.10.1016/j.neu int.2013.0 9.014 (e-pub ahead of print)
    • Whyte A, Jessen T, Varney S, Carneiro AM. Serotonin transporter and integrin beta 3 genes interact to modulate serotonin uptake in mouse brain. Neurochem Int. advance online publication, 28 September 2013; doi:pii:S0197-0186(13)00241-6.10.1016/j.neuint.2013.09.014 (e-pub ahead of print).
    • (2013) Neurochem Int.
    • Whyte, A.1    Jessen, T.2    Varney, S.3    Carneiro, A.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.