EZH2 in normal hematopoiesis and hematological malignancies

Oncotarget

Volumn 7, Issue 3, 2016, Pages 2284-2296

  Herviou, Laurie ^b   Cavalli, Giacomo ^b   Cartron, Guillaume ^a,c   Klein, Bernard ^a,b,c   Moreaux, Jérôme ^a,b,c  

^a MONTPELLIER UNIVERSITY HOSPITAL   (France)

^b INSTITUTE OF HUMAN GENETICS   (France)

^c UNIV MONTPELLIER   (France)

Author keywords

EZH2; Hematological malignancies; Polycomb complex; Therapeutic target

Indexed keywords

3 DEAZANEPLANOCIN A; ANTINEOPLASTIC AGENT; DNA METHYLTRANSFERASE; E 11; E 7438; EPZ 005787; GSK 126; HISTIDINE; LYSINE; POLYCOMB GROUP PROTEIN; POLYCOMB REPRESSIVE COMPLEX 2; TAZEMETOSTAT; TRANSCRIPTION FACTOR EZH2; UNCLASSIFIED DRUG; 3-DEAZANEPLANOCIN; ADENOSINE; EPZ011652; ETHYLENEDIAMINE DERIVATIVE; EZH2 PROTEIN, HUMAN; GSK126; HISTONE; INDOLE DERIVATIVE; PYRAZOLE DERIVATIVE; PYRIDONE DERIVATIVE;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; B CELL LYMPHOMA; B LYMPHOCYTE; CANCER INHIBITION; CANCER SURVIVAL; CELL DIFFERENTIATION; DRUG EFFICACY; DRUG MECHANISM; DRUG RESPONSE; DRUG SAFETY; DRUG SELECTIVITY; EZH2 GENE; G1 PHASE CELL CYCLE CHECKPOINT; GAIN OF FUNCTION MUTATION; GENE OVEREXPRESSION; GENE REPRESSION; HEMATOLOGIC MALIGNANCY; HEMATOPOIESIS; HUMAN; LOSS OF FUNCTION MUTATION; METHYLATION; MOLECULARLY TARGETED THERAPY; MULTICENTER STUDY (TOPIC); MYELOID LEUKEMIA; MYELOPROLIFERATIVE NEOPLASM; NONHUMAN; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SOMATIC MUTATION; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; CELL PROLIFERATION; CYTOLOGY; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; HEMATOLOGIC NEOPLASMS; HEMATOPOIETIC STEM CELL; METABOLISM; PATHOLOGY; PERSONALIZED MEDICINE; PHYSIOLOGY;

ADENOSINE; B-LYMPHOCYTES; CELL DIFFERENTIATION; CELL PROLIFERATION; ENHANCER OF ZESTE HOMOLOG 2 PROTEIN; EPIGENESIS, GENETIC; ETHYLENEDIAMINES; GENE EXPRESSION REGULATION; HEMATOLOGIC NEOPLASMS; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; HISTONES; HUMANS; INDOLES; METHYLATION; POLYCOMB REPRESSIVE COMPLEX 2; PRECISION MEDICINE; PYRAZOLES; PYRIDONES;

EID: 84962325949     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.6198     Document Type: Article

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