-
1
-
-
79957525895
-
Hematopoietic cell regulation of osteoblast proliferation and differentiation
-
Bethel, M., Srour, E. F., and Kacena, M. A. (2011) Hematopoietic cell regulation of osteoblast proliferation and differentiation. Curr. Osteoporos. Rep. 9, 96-102
-
(2011)
Curr. Osteoporos. Rep.
, vol.9
, pp. 96-102
-
-
Bethel, M.1
Srour, E.F.2
Kacena, M.A.3
-
2
-
-
77749309917
-
Immature and mature megakaryocytes enhance osteoblast proliferation and inhibit osteoclast formation
-
Ciovacco, W. A., Cheng, Y. H., Horowitz, M. C., and Kacena, M. A. (2010) Immature and mature megakaryocytes enhance osteoblast proliferation and inhibit osteoclast formation. J. Cell. Biochem. 109, 774-781
-
(2010)
J. Cell. Biochem.
, vol.109
, pp. 774-781
-
-
Ciovacco, W.A.1
Cheng, Y.H.2
Horowitz, M.C.3
Kacena, M.A.4
-
3
-
-
33749529089
-
A reciprocal regulatory interaction between megakaryocytes, bone cells, and hematopoietic stem cells
-
DOI 10.1016/j.bone.2006.05.019, PII S8756328206005515
-
Kacena, M. A., Gundberg, C. M., and Horowitz, M. C. (2006) A reciprocal regulatory interaction between megakaryocytes, bone cells, and hematopoietic stem cells. Bone 39, 978-984 (Pubitemid 44528390)
-
(2006)
Bone
, vol.39
, Issue.5
, pp. 978-984
-
-
Kacena, M.A.1
Gundberg, C.M.2
Horowitz, M.C.3
-
4
-
-
57449118281
-
The role of gap junctions in megakaryocyte-mediated osteoblast proliferation and differentiation
-
Ciovacco, W. A., Goldberg, C. G., Taylor, A. F., Lemieux, J. M., Horowitz, M. C., Donahue, H. J., and Kacena, M. A. (2009) The role of gap junctions in megakaryocyte-mediated osteoblast proliferation and differentiation. Bone 44, 80-86
-
(2009)
Bone
, vol.44
, pp. 80-86
-
-
Ciovacco, W.A.1
Goldberg, C.G.2
Taylor, A.F.3
Lemieux, J.M.4
Horowitz, M.C.5
Donahue, H.J.6
Kacena, M.A.7
-
6
-
-
3142669441
-
Megakaryocyte-osteoblast interaction revealed in mice deficient in transcription factors GATA-1 and NF-E2
-
DOI 10.1359/JBMR.0301254
-
Kacena, M. A., Shivdasani, R. A., Wilson, K., Xi, Y., Troiano, N., Nazarian, A., Gundberg, C. M., Bouxsein, M. L., Lorenzo, J. A., and Horowitz, M. C. (2004) Megakaryocyte-osteoblast interaction revealed in mice deficient in transcription factors GATA-1 and NF-E2. J. Bone Miner. Res. 19, 652-660 (Pubitemid 41071226)
-
(2004)
Journal of Bone and Mineral Research
, vol.19
, Issue.4
, pp. 652-660
-
-
Kacena, M.A.1
Shivdasani, R.A.2
Wilson, K.3
Xi, Y.4
Troiano, N.5
Nazarian, A.6
Gundberg, C.M.7
Bouxsein, M.L.8
Lorenzo, J.A.9
Horowitz, M.C.10
-
7
-
-
34547453984
-
Proline-rich tyrosine kinase 2 regulates osteoprogenitor cells and bone formation, and offers an anabolic treatment approach for osteoporosis
-
DOI 10.1073/pnas.0701421104
-
Buckbinder, L., Crawford, D. T., Qi, H., Ke, H. Z., Olson, L. M., Long, K. R., Bonnette, P. C., Baumann, A. P., Hambor, J. E., Grasser, W. A., 3rd, Pan, L. C., Owen, T. A., Luzzio, M. J., Hulford, C. A., Gebhard, D. F., Paralkar, V. M., Simmons, H. A., Kath, J. C., Roberts, W. G., Smock, S. L., Guzman-Perez, A., Brown, T. A., and Li, M. (2007) Proline-rich tyrosine kinase 2 regulates osteoprogenitor cells and bone formation and offers an anabolic treatment approach for osteoporosis. Proc. Natl. Acad. Sci. U.S.A. 104, 10619-10624 (Pubitemid 47185714)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.25
, pp. 10619-10624
-
-
Buckbinder, L.1
Crawford, D.T.2
Qi, H.3
Hua, Z.K.4
Olson, L.M.5
Long, K.R.6
Bonnette, P.C.7
Baumann, A.P.8
Hambor, J.E.9
Grasser III, W.A.10
Pan, L.C.11
Owen, T.A.12
Luzzio, M.J.13
Hulford, C.A.14
Gebhard, D.F.15
Paralkar, V.M.16
Simmons, H.A.17
Kath, J.C.18
Roberts, W.G.19
Smock, S.L.20
Guzman-Perez, A.21
Brown, T.A.22
Li, M.23
more..
-
8
-
-
0032168740
-
3 integrin, and phosphorylated by Src kinase
-
3 integrin, and phosphorylated by Src kinase. J. Clin. Invest. 102, 881-892
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 881-892
-
-
Duong, L.T.1
Lakkakorpi, P.T.2
Nakamura, I.3
Machwate, M.4
Nagy, R.M.5
Rodan, G.A.6
-
9
-
-
3142755633
-
Mechanical strain on osteoblasts activates autophosphorylation of focal adhesion kinase and proline-rich tyrosine kinase 2 tyrosine sites involved in ERK activation
-
DOI 10.1074/jbc.M313244200
-
Boutahar, N., Guignandon, A., Vico, L., and Lafage-Proust, M. H. (2004) Mechanical strain on osteoblasts activates autophosphorylation of focal adhesion kinase and proline-rich tyrosine kinase 2 tyrosine sites involved in ERK activation. J. Biol. Chem. 279, 30588-30599 (Pubitemid 38937991)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.29
, pp. 30588-30599
-
-
Boutahar, N.1
Guignandon, A.2
Vico, L.3
Lafage-Proust, M.-H.4
-
10
-
-
3242656613
-
PYK2 and FAK in osteoclasts
-
Xiong, W. C., and Feng, X. (2003) PYK2 and FAK in osteoclasts. Front. Biosci. 8, d1219-d1226
-
(2003)
Front. Biosci.
, vol.8
-
-
Xiong, W.C.1
Feng, X.2
-
11
-
-
34548845081
-
-/- mice
-
DOI 10.1083/jcb.200701148
-
Gil-Henn, H., Destaing, O., Sims, N. A., Aoki, K., Alles, N., Neff, L., Sanjay, A., Bruzzaniti, A., De Camilli, P., Baron, R., and Schlessinger, J. (2007) Defective microtubule-dependent podosome organization in osteoclasts leads to increased bone density in Pyk2-/- mice. J. Cell Biol. 178, 1053-1064 (Pubitemid 47443326)
-
(2007)
Journal of Cell Biology
, vol.178
, Issue.6
, pp. 1053-1064
-
-
Gil-Henn, H.1
Destaing, O.2
Sims, N.A.3
Aoki, K.4
Alles, N.5
Neff, L.6
Sanjay, A.7
Bruzzaniti, A.8
De Camilli, P.9
Baron, R.10
Schlessinger, J.11
-
12
-
-
0035825121
-
3 integrin-mediated signaling, cell adhesion, and osteoclast motility
-
3 integrin-mediated signaling, cell adhesion, and osteoclast motility. J. Cell Biol. 152, 181-195
-
(2001)
J. Cell Biol.
, vol.152
, pp. 181-195
-
-
Sanjay, A.1
Houghton, A.2
Neff, L.3
DiDomenico, E.4
Bardelay, C.5
Antoine, E.6
Levy, J.7
Gailit, J.8
Bowtell, D.9
Horne, W.C.10
Baron, R.11
-
13
-
-
38149070791
-
Nuclear FAK promotes cell proliferation and survival through FERM-enhanced p53 degradation
-
Lim, S. T., Chen, X. L., Lim, Y., Hanson, D. A., Vo, T. T., Howerton, K., Larocque, N., Fisher, S. J., Schlaepfer, D. D., and Ilic, D. (2008) Nuclear FAK promotes cell proliferation and survival through FERM-enhanced p53 degradation. Mol. Cell 29, 9-22
-
(2008)
Mol. Cell
, vol.29
, pp. 9-22
-
-
Lim, S.T.1
Chen, X.L.2
Lim, Y.3
Hanson, D.A.4
Vo, T.T.5
Howerton, K.6
Larocque, N.7
Fisher, S.J.8
Schlaepfer, D.D.9
Ilic, D.10
-
14
-
-
76249097844
-
Pyk2 inhibition of p53 as an adaptive and intrinsic mechanism facilitating cell proliferation and survival
-
Lim, S. T., Miller, N. L., Nam, J. O., Chen, X. L., Lim, Y., and Schlaepfer, D. D. (2010) Pyk2 inhibition of p53 as an adaptive and intrinsic mechanism facilitating cell proliferation and survival. J. Biol. Chem. 285, 1743-1753
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 1743-1753
-
-
Lim, S.T.1
Miller, N.L.2
Nam, J.O.3
Chen, X.L.4
Lim, Y.5
Schlaepfer, D.D.6
-
15
-
-
0028037648
-
Expression and regulation of Ly-6 differentiation antigens by murine osteoblasts
-
DOI 10.1210/en.135.3.1032
-
Horowitz, M. C., Fields, A., DeMeo, D., Qian, H. Y., Bothwell, A. L., and Trepman, E. (1994) Expression and regulation of Ly-6 differentiation antigens by murine osteoblasts. Endocrinology 135, 1032-1043 (Pubitemid 24271195)
-
(1994)
Endocrinology
, vol.135
, Issue.3
, pp. 1032-1043
-
-
Horowitz, M.C.1
Fields, A.2
Demeo, D.3
Qian, H.-Y.4
Bothwell, A.L.M.5
Trepman, E.6
-
16
-
-
0016820226
-
Target cells in bone for parathormone and calcitonin are different. Enrichment for each cell type by sequential digestion of mouse calvaria and selective adhesion to polymeric surfaces
-
Wong, G. L., and Cohn, D. V. (1975) Target cells in bone for parathormone and calcitonin are different. Enrichment for each cell type by sequential digestion of mouse calvaria and selective adhesion to polymeric surfaces. Proc. Natl. Acad. Sci. U.S.A. 72, 3167-3171
-
(1975)
Proc. Natl. Acad. Sci. U.S.A.
, vol.72
, pp. 3167-3171
-
-
Wong, G.L.1
Cohn, D.V.2
-
17
-
-
0020328961
-
Formation of bone by isolated, cultured osteoblasts in millipore diffusion chambers
-
Simmons, D. J., Kent, G. N., Jilka, R. L., Scott, D. M., Fallon, M., and Cohn, D. V. (1982) Formation of bone by isolated, cultured osteoblasts in Millipore diffusion chambers. Calcif. Tissue Int. 34, 291-294 (Pubitemid 12060443)
-
(1982)
Calcified Tissue International
, vol.34
, Issue.3
, pp. 291-294
-
-
Simmons, D.J.1
Kent, G.N.2
Jilka, R.L.3
-
18
-
-
0019407729
-
Role of phosphodiesterase in the parathormone-stimulated adenosine 3',5'-monophosphate response in bone cell populations enriched in osteoclasts and osteoblasts
-
Jilka, R. L., and Cohn, D. V. (1981) Role of phosphodiesterase in the parathormone-stimulated adenosine 3′,5′-monophosphate response in bone cell populations enriched in osteoclasts and osteoblasts. Endocrinology 109, 743-747 (Pubitemid 11052101)
-
(1981)
Endocrinology
, vol.109
, Issue.3
, pp. 743-747
-
-
Jilka, R.L.1
Cohn, D.V.2
-
19
-
-
33749518042
-
Megakaryocyte-mediated inhibition of osteoclast development
-
DOI 10.1016/j.bone.2006.05.004, PII S875632820600487X
-
Kacena, M. A., Nelson, T., Clough, M. E., Lee, S. K., Lorenzo, J. A., Gundberg, C. M., and Horowitz, M. C. (2006) Megakaryocyte-mediated inhibition of osteoclast development. Bone 39, 991-999 (Pubitemid 44528382)
-
(2006)
Bone
, vol.39
, Issue.5
, pp. 991-999
-
-
Kacena, M.A.1
Nelson, T.2
Clough, M.E.3
Lee, S.-K.4
Lorenzo, J.A.5
Gundberg, C.M.6
Horowitz, M.C.7
-
20
-
-
84861219860
-
Pyk2 regulates megakaryocyte-induced osteoblast proliferation in vitro and bone formation in vivo
-
Bruzzaniti, A., Cheng, Y. H., Huang, S., Nguyen, K., Chitteti, B. R., Srour, E. F., Mayo, L. D., and Kacena, M. (2010) Pyk2 regulates megakaryocyte-induced osteoblast proliferation in vitro and bone formation in vivo. J. Bone Miner. Res. 25, Suppl. 1, SU0248
-
(2010)
J. Bone Miner. Res.
, vol.25
, Issue.SUPPL. 1
-
-
Bruzzaniti, A.1
Cheng, Y.H.2
Huang, S.3
Nguyen, K.4
Chitteti, B.R.5
Srour, E.F.6
Mayo, L.D.7
Kacena, M.8
-
21
-
-
84882555181
-
-
(Bilezikian, J. P., Raisz, L. G., and Martin, T. J., eds) Elsevier Inc., San Diego
-
Schinke, T., and Karsenty, G. (2008) in Principals of Bone Biology (Bilezikian, J. P., Raisz, L. G., and Martin, T. J., eds) pp. 109-119, Elsevier Inc., San Diego
-
(2008)
Principals of Bone Biology
, pp. 109-119
-
-
Schinke, T.1
Karsenty, G.2
-
22
-
-
79959827697
-
PYK2 signaling is required for PDGF-dependent vascular smooth muscle cell proliferation
-
Perez, J., Torres, R. A., Rocic, P., Cismowski, M. J., Weber, D. S., Darley-Usmar, V. M., and Lucchesi, P. A. (2011) PYK2 signaling is required for PDGF-dependent vascular smooth muscle cell proliferation. Am. J. Physiol. Cell Physiol. 301, C242-C251
-
(2011)
Am. J. Physiol. Cell Physiol.
, vol.301
-
-
Perez, J.1
Torres, R.A.2
Rocic, P.3
Cismowski, M.J.4
Weber, D.S.5
Darley-Usmar, V.M.6
Lucchesi, P.A.7
-
23
-
-
61449173959
-
cAMP and Pyk2 interact to regulate prostate cell proliferation and function
-
Kisslinger, A., Cantile, M., Sparaneo, G., Vitale, N., Fabbrocini, G., Chieffi, P., Cillo, C., Mancini, F. P., and Tramontano, D. (2009) cAMP and Pyk2 interact to regulate prostate cell proliferation and function. Cancer Biol. Ther. 8, 236-242
-
(2009)
Cancer Biol. Ther.
, vol.8
, pp. 236-242
-
-
Kisslinger, A.1
Cantile, M.2
Sparaneo, G.3
Vitale, N.4
Fabbrocini, G.5
Chieffi, P.6
Cillo, C.7
Mancini, F.P.8
Tramontano, D.9
-
24
-
-
56049123161
-
Proline-rich tyrosine kinase 2 (Pyk2) promotes proliferation and invasiveness of hepatocellular carcinoma cells through c-Src/ERK activation
-
Sun, C. K., Man, K., Ng, K. T., Ho, J. W., Lim, Z. X., Cheng, Q., Lo, C. M., Poon, R. T., and Fan, S. T. (2008) Proline-rich tyrosine kinase 2 (Pyk2) promotes proliferation and invasiveness of hepatocellular carcinoma cells through c-Src/ERK activation. Carcinogenesis 29, 2096-2105
-
(2008)
Carcinogenesis
, vol.29
, pp. 2096-2105
-
-
Sun, C.K.1
Man, K.2
Ng, K.T.3
Ho, J.W.4
Lim, Z.X.5
Cheng, Q.6
Lo, C.M.7
Poon, R.T.8
Fan, S.T.9
-
26
-
-
14144251106
-
Loss of the transcription factor p45 NF-E2 results in a developmental arrest of megakaryocyte differentiation and the onset of a high bone mass phenotype
-
DOI 10.1016/j.bone.2004.09.024
-
Kacena, M. A., Gundberg, C. M., Nelson, T., and Horowitz, M. C. (2005) Loss of the transcription factor p45 NF-E2 results in a developmental arrest of megakaryocyte differentiation and the onset of a high bone mass phenotype. Bone 36, 215-223 (Pubitemid 40283578)
-
(2005)
Bone
, vol.36
, Issue.2
, pp. 215-223
-
-
Kacena, M.A.1
Gundberg, C.M.2
Nelson, T.3
Horowitz, M.C.4
-
27
-
-
33645126422
-
Cyclic strain promote shuttling of PYK2/Hic-5 complex from focal contacts in osteoblast-like cells
-
Guignandon, A., Boutahar, N., Rattner, A., Vico, L., and Lafage-Proust, M. H. (2006) Cyclic strain promote shuttling of PYK2/Hic-5 complex from focal contacts in osteoblast-like cells. Biochem. Biophys. Res. Commun. 343, 407-414
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.343
, pp. 407-414
-
-
Guignandon, A.1
Boutahar, N.2
Rattner, A.3
Vico, L.4
Lafage-Proust, M.H.5
-
28
-
-
0033848751
-
3- integrin expression
-
Wozniak, M., Fausto, A., Carron, C. P., Meyer, D. M., and Hruska, K. A. (2000) Mechanically strained cells of the osteoblast lineage organize their extracellular matrix through unique sites of αvβ3-integrin expression. J. Bone Miner. Res. 15, 1731-1745 (Pubitemid 30666227)
-
(2000)
Journal of Bone and Mineral Research
, vol.15
, Issue.9
, pp. 1731-1745
-
-
Wozniak, M.1
Fausto, A.2
Carron, C.P.3
Meyer, D.M.4
Hruska, K.A.5
-
29
-
-
0036780031
-
Effects of prostaglandins E1 and E2 on the growth and differentiation of osteoblast-like cells cultured in vitro
-
Conconi, M. T., Tommasini, M., Baiguera, S., De Coppi, P., Parnigotto, P. P., and Nussdorfer, G. G. (2002) Effects of prostaglandins E1 and E2 on the growth and differentiation of osteoblast-like cells cultured in vitro. Int. J. Mol. Med. 10, 451-456
-
(2002)
Int. J. Mol. Med.
, vol.10
, pp. 451-456
-
-
Conconi, M.T.1
Tommasini, M.2
Baiguera, S.3
De Coppi, P.4
Parnigotto, P.P.5
Nussdorfer, G.G.6
-
30
-
-
49149087652
-
The effect of combined application of TGFβ-1, BMP-2, and COLLOSS e on the development of bone marrow-derived osteoblast-like cells in vitro
-
van der Zande, M., Walboomers, X. F., Briest, A., Springer, M., Alava, J. I., and Jansen, J. A. (2008) The effect of combined application of TGFβ-1, BMP-2, and COLLOSS E on the development of bone marrow-derived osteoblast-like cells in vitro. J. Biomed. Mater. Res. A 86, 788-795
-
(2008)
J. Biomed. Mater. Res. A
, vol.86
, pp. 788-795
-
-
Van Der Zande, M.1
Walboomers, X.F.2
Briest, A.3
Springer, M.4
Alava, J.I.5
Jansen, J.A.6
-
31
-
-
34548801436
-
Activation of PKA and phosphorylation of sodium-dependent vitamin C transporter 2 by prostaglandin E2 promote osteoblast-like differentiation in MC3T3-E1 cells
-
DOI 10.1038/sj.cdd.4402190, PII 4402190
-
Wu, X., Zeng, L. H., Taniguchi, T., and Xie, Q. M. (2007) Activation of PKA and phosphorylation of sodium-dependent vitamin C transporter 2 by prostaglandin E2 promote osteoblast-like differentiation in MC3T3-E1 cells. Cell Death Differ. 14, 1792-1801 (Pubitemid 47423646)
-
(2007)
Cell Death and Differentiation
, vol.14
, Issue.10
, pp. 1792-1801
-
-
Wu, X.1
Zeng, L.-H.2
Taniguchi, T.3
Xie, Q.-M.4
-
32
-
-
0023202335
-
Expression of differentiated function by mineralizing cultures of chicken osteoblasts
-
Gerstenfeld, L. C., Chipman, S. D., Glowacki, J., and Lian, J. B. (1987) Expression of differentiated function by mineralizing cultures of chicken osteoblasts. Dev. Biol. 122, 49-60 (Pubitemid 17113169)
-
(1987)
Developmental Biology
, vol.122
, Issue.1
, pp. 49-60
-
-
Gerstenfeld, L.C.1
Chipman, S.D.2
Glowacki, J.3
Lian, J.B.4
-
33
-
-
0037838889
-
PYK2 autophosphorylation, but not kinase activity, is necessary for adhesion-induced association with c-Src, osteoclast spreading, and bone resorption
-
DOI 10.1074/jbc.M206579200
-
Lakkakorpi, P. T., Bett, A. J., Lipfert, L., Rodan, G. A., and Duong le, T. (2003) PYK2 autophosphorylation, but not kinase activity, is necessary for adhesion-induced association with c-Src, osteoclast spreading, and bone resorption. J. Biol. Chem. 278, 11502-11512 (Pubitemid 36792711)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.13
, pp. 11502-11512
-
-
Lakkakorpi, P.T.1
Bett, A.J.2
Lipfert, L.3
Rodan, G.A.4
Duong, L.T.5
-
34
-
-
0041829483
-
Protein kinase Cε-dependent activation of proline-rich tyrosine kinase 2 in neonatal rat ventricular myocytes
-
DOI 10.1016/S0022-2828(03)00228-1
-
Bayer, A. L., Heidkamp, M. C., Howes, A. L., Heller Brown, J., Byron, K. L., and Samarel, A. M. (2003) Protein kinase C ε-dependent activation of proline-rich tyrosine kinase 2 in neonatal rat ventricular myocytes. J. Mol. Cell. Cardiol. 35, 1121-1133 (Pubitemid 37083256)
-
(2003)
Journal of Molecular and Cellular Cardiology
, vol.35
, Issue.9
, pp. 1121-1133
-
-
Bayer, A.L.1
Heidkamp, M.C.2
Howes, A.L.3
Heller, B.J.4
Byron, K.L.5
Samarel, A.M.6
-
35
-
-
0030657557
-
Cross-talk between phorbol ester-mediated signaling and tyrosine kinase proto-oncogenes: II. Comparison of phorbol ester and sphingomyelinase- induced phosphorylation of ErbB2 and ErbB3
-
DOI 10.1074/jbc.272.49.31182
-
Emkey, R., and Kahn, C. R. (1997) Cross-talk between phorbol ester-mediated signaling and tyrosine kinase proto-oncogenes. II. Comparison of phorbol ester and sphingomyelinase-induced phosphorylation of ErbB2 and ErbB3. J. Biol. Chem. 272, 31182-31189 (Pubitemid 27527569)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.49
, pp. 31182-31189
-
-
Emkey, R.1
Kahn, C.R.2
-
36
-
-
0034656081
-
Involvement of proline-rich tyrosine kinase 2 in platelet activation: Tyrosine phosphorylation mostly dependent on αIIbß3 integrin and protein kinase C, translocation to the cytoskeleton and association with Shc through Grb2
-
DOI 10.1042/0264-6021:3470561
-
Ohmori, T., Yatomi, Y., Asazuma, N., Satoh, K., and Ozaki, Y. (2000) Involvement of proline-rich tyrosine kinase 2 in platelet activation. Tyrosine phosphorylation mostly dependent on αIIbß3 integrin and protein kinase C, translocation to the cytoskeleton, and association with Shc through Grb2. Biochem. J. 347, 561-569 (Pubitemid 30229405)
-
(2000)
Biochemical Journal
, vol.347
, Issue.2
, pp. 561-569
-
-
Ohmori, T.1
Yatomi, Y.2
Asazuma, N.3
Satoh, K.4
Ozaki, Y.5
-
37
-
-
0028244823
-
Jasplakinolide, a cytotoxic natural product, induces actin polymerization and competitively inhibits the binding of phalloidin to F-actin
-
Bubb, M. R., Senderowicz, A. M., Sausville, E. A., Duncan, K. L., and Korn, E. D. (1994) Jasplakinolide, a cytotoxic natural product, induces actin polymerization and competitively inhibits the binding of phalloidin to F-actin. J. Biol. Chem. 269, 14869-14871 (Pubitemid 24198320)
-
(1994)
Journal of Biological Chemistry
, vol.269
, Issue.21
, pp. 14869-14871
-
-
Bubb, M.R.1
Senderowicz, A.M.J.2
Sausville, E.A.3
Duncan, K.L.K.4
Korn, E.D.5
-
38
-
-
0029610432
-
Identification of actin as a substrate of ICE and an ICE-like protease and involvement of an ICE-like protease but not ICE in VP-16-induced U937 apoptosis
-
DOI 10.1006/bbrc.1995.2894
-
Mashima, T., Naito, M., Fujita, N., Noguchi, K., and Tsuruo, T. (1995) Identification of actin as a substrate of ICE and an ICE-like protease and involvement of an ICE-like protease but not ICE in VP-16-induced U937 apoptosis. Biochem. Biophys. Res. Commun. 217, 1185-1192 (Pubitemid 26019777)
-
(1995)
Biochemical and Biophysical Research Communications
, vol.217
, Issue.3
, pp. 1185-1192
-
-
Mashima, T.1
Naito, M.2
Fujita, N.3
Noguchi, K.4
Tsuruo, T.5
-
39
-
-
0033561495
-
Caspase-mediated cleavage of cytoskeletal actin plays a positive role in the process of morphological apoptosis
-
DOI 10.1038/sj.onc.1202558
-
Mashima, T., Naito, M., and Tsuruo, T. (1999) Caspase-mediated cleavage of cytoskeletal actin plays a positive role in the process of morphological apoptosis. Oncogene 18, 2423-2430 (Pubitemid 29206155)
-
(1999)
Oncogene
, vol.18
, Issue.15
, pp. 2423-2430
-
-
Mashima, T.1
Naito, M.2
Tsuruo, T.3
-
40
-
-
0031746871
-
Dismantling in cell death: Molecular mechanisms and relationship to caspase activation
-
DOI 10.1046/j.1365-3083.1998.00363.x
-
Depraetere, V., and Golstein, P. (1998) Dismantling in cell death. Molecular mechanisms and relationship to caspase activation. Scand. J. Immunol. 47, 523-531 (Pubitemid 28273361)
-
(1998)
Scandinavian Journal of Immunology
, vol.47
, Issue.6
, pp. 523-531
-
-
Depraetere, V.1
Golstein, P.2
-
41
-
-
0030931876
-
Caspases. The executioners of apoptosis
-
Cohen, G. M. (1997) Caspases. The executioners of apoptosis. Biochem. J. 326, 1-16
-
(1997)
Biochem. J.
, vol.326
, pp. 1-16
-
-
Cohen, G.M.1
-
42
-
-
0036493384
-
+ cells transplanted into conditioned NOD/SCID recipients
-
+ cells transplanted into conditioned NOD/SCID recipients. Blood 99, 1585-1593
-
(2002)
Blood
, vol.99
, pp. 1585-1593
-
-
Jetmore, A.1
Plett, P.A.2
Tong, X.3
Wolber, F.M.4
Breese, R.5
Abonour, R.6
Orschell-Traycoff, C.M.7
Srour, E.F.8
-
43
-
-
1642461401
-
Caspase activation independent of cell death is required for proper cell dispersal and correct morphology in PC12 cells
-
DOI 10.1016/j.yexcr.2003.12.029, PII S0014482704000047
-
Rohn, T. T., Cusack, S. M., Kessinger, S. R., and Oxford, J. T. (2004) Caspase activation independent of cell death is required for proper cell dispersal and correct morphology in PC12 cells. Exp. Cell Res. 295, 215-225 (Pubitemid 38407358)
-
(2004)
Experimental Cell Research
, vol.295
, Issue.1
, pp. 215-225
-
-
Rohn, T.T.1
Cusack, S.M.2
Kessinger, S.R.3
Oxford, J.T.4
-
44
-
-
0035997542
-
Angiotensin II-augmented migration of VSMCs towards PDGF-BB involves Pyk2 and ERK 1/2 activation
-
DOI 10.1007/s00395-002-0357-8
-
Blaschke, F., Stawowy, P., Kappert, K., Goetze, S., Kintscher, U., Wollert-Wulf, B., Fleck, E., and Graf, K. (2002) Angiotensin II-augmented migration of VSMCs toward PDGF-BB involves Pyk2 and ERK 1/2 activation. Basic Res. Cardiol. 97, 334-342 (Pubitemid 34808780)
-
(2002)
Basic Research in Cardiology
, vol.97
, Issue.4
, pp. 334-342
-
-
Blaschke, F.1
Stawowy, P.2
Kappert, K.3
Goetze, S.4
Kintscher, U.5
Wollert-Wulf, B.6
Fleck, E.7
Graf, K.8
-
45
-
-
70349574479
-
Restoration and reversible expansion of the osteoblastic hematopoietic stem cell niche after marrow radioablation
-
Dominici, M., Rasini, V., Bussolari, R., Chen, X., Hofmann, T. J., Spano, C., Bernabei, D., Veronesi, E., Bertoni, F., Paolucci, P., Conte, P., and Horwitz, E. M. (2009) Restoration and reversible expansion of the osteoblastic hematopoietic stem cell niche after marrow radioablation. Blood 114, 2333-2343
-
(2009)
Blood
, vol.114
, pp. 2333-2343
-
-
Dominici, M.1
Rasini, V.2
Bussolari, R.3
Chen, X.4
Hofmann, T.J.5
Spano, C.6
Bernabei, D.7
Veronesi, E.8
Bertoni, F.9
Paolucci, P.10
Conte, P.11
Horwitz, E.M.12
-
46
-
-
0034693049
-
Targeting of PYK2 to focal adhesions as a cellular mechanism for convergence between integrins and G protein-coupled receptor signaling cascades
-
Litvak, V., Tian, D., Shaul, Y. D., and Lev, S. (2000) Targeting of PYK2 to focal adhesions as a cellular mechanism for convergence between integrins and G protein-coupled receptor signaling cascades. J. Biol. Chem. 275, 32736-32746
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 32736-32746
-
-
Litvak, V.1
Tian, D.2
Shaul, Y.D.3
Lev, S.4
-
47
-
-
3042730952
-
Recruitment of Pyk2 and Cbl to lipid rafts mediates signals important for actin reorganization in growing neurites
-
DOI 10.1242/jcs.01148
-
Haglund, K., Ivankovic-Dikic, I., Shimokawa, N., Kruh, G. D., and Dikic, I. (2004) Recruitment of Pyk2 and Cbl to lipid rafts mediates signals important for actin reorganization in growing neurites. J. Cell Sci. 117, 2557-2568 (Pubitemid 38877851)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.12
, pp. 2557-2568
-
-
Haglund, K.1
Ivankovic-Dikic, I.2
Shimokawa, N.3
Kruh, G.D.4
Dikic, I.5
-
48
-
-
77955484577
-
Suppressor of cytokine signaling 2 regulates IL-15-primed human NK cell function via control of phosphorylated Pyk2
-
Lee, S. H., Yun, S., Piao, Z. H., Jeong, M., Kim, D. O., Jung, H., Lee, J., Kim, M. J., Kim, M. S., Chung, J. W., Kim, T. D., Yoon, S. R., Greenberg, P. D., and Choi, I. (2010) Suppressor of cytokine signaling 2 regulates IL-15-primed human NK cell function via control of phosphorylated Pyk2. J. Immunol. 185, 917-928
-
(2010)
J. Immunol.
, vol.185
, pp. 917-928
-
-
Lee, S.H.1
Yun, S.2
Piao, Z.H.3
Jeong, M.4
Kim, D.O.5
Jung, H.6
Lee, J.7
Kim, M.J.8
Kim, M.S.9
Chung, J.W.10
Kim, T.D.11
Yoon, S.R.12
Greenberg, P.D.13
Choi, I.14
-
49
-
-
26944437142
-
Phospho-caveolin-1 mediates integrin-regulated membrane domain internalization
-
DOI 10.1038/ncb1293, PII N1293
-
del Pozo, M. A., Balasubramanian, N., Alderson, N. B., Kiosses, W. B., Grande-García, A., Anderson, R. G., and Schwartz, M. A. (2005) Phosphocaveolin-1 mediates integrin-regulated membrane domain internalization. Nat. Cell Biol. 7, 901-908 (Pubitemid 41486291)
-
(2005)
Nature Cell Biology
, vol.7
, Issue.9
, pp. 901-908
-
-
Del, P.M.A.1
Balasubramanian, N.2
Alderson, N.B.3
Kiosses, W.B.4
Grande-Garcia, A.5
Anderson, R.G.W.6
Schwartz, M.A.7
-
50
-
-
66149127739
-
Caveolin-1 regulates the antagonistic pleiotropic properties of cellular senescence through a novel Mdm2/p53-mediated pathway
-
Bartholomew, J. N., Volonte, D., and Galbiati, F. (2009) Caveolin-1 regulates the antagonistic pleiotropic properties of cellular senescence through a novel Mdm2/p53-mediated pathway. Cancer Res. 69, 2878-2886
-
(2009)
Cancer Res.
, vol.69
, pp. 2878-2886
-
-
Bartholomew, J.N.1
Volonte, D.2
Galbiati, F.3
-
51
-
-
0031846188
-
Expression and characterization of splice variants of PYK2, a focal adhesion kinase-related protein
-
Xiong, W. C., Macklem, M., and Parsons, J. T. (1998) Expression and characterization of splice variants of PYK2, a focal adhesion kinase-related protein. J. Cell Sci. 111, 1981-1991 (Pubitemid 28391064)
-
(1998)
Journal of Cell Science
, vol.111
, Issue.14
, pp. 1981-1991
-
-
Xiong, W.-C.1
Macklem, M.2
Parsons, J.T.3
-
52
-
-
65749105992
-
Structural characterization of proline-rich tyrosine kinase 2 (PYK2) reveals a unique (DFG-out) conformation and enables inhibitor design
-
Han, S., Mistry, A., Chang, J. S., Cunningham, D., Griffor, M., Bonnette, P. C., Wang, H., Chrunyk, B. A., Aspnes, G. E., Walker, D. P., Brosius, A. D., and Buckbinder, L. (2009) Structural characterization of proline-rich tyrosine kinase 2 (PYK2) reveals a unique (DFG-out) conformation and enables inhibitor design. J. Biol. Chem. 284, 13193-13201
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 13193-13201
-
-
Han, S.1
Mistry, A.2
Chang, J.S.3
Cunningham, D.4
Griffor, M.5
Bonnette, P.C.6
Wang, H.7
Chrunyk, B.A.8
Aspnes, G.E.9
Walker, D.P.10
Brosius, A.D.11
Buckbinder, L.12
-
53
-
-
34250172718
-
Reconciling the roles of FAK in osteoblast differentiation, osteoclast remodeling, and bone regeneration
-
DOI 10.1016/j.bone.2007.01.024, PII S8756328207000452
-
Kim, J. B., Leucht, P., Luppen, C. A., Park, Y. J., Beggs, H. E., Damsky, C. H., and Helms, J. A. (2007) Reconciling the roles of FAK in osteoblast differentiation, osteoclast remodeling, and bone regeneration. Bone 41, 39-51 (Pubitemid 46901054)
-
(2007)
Bone
, vol.41
, Issue.1
, pp. 39-51
-
-
Kim, J.-B.1
Leucht, P.2
Luppen, C.A.3
Park, Y.J.4
Beggs, H.E.5
Damsky, C.H.6
Helms, J.A.7
-
54
-
-
1642401132
-
Accelerated cell cycle progression in osteoblasts overexpressing the c-Fos proto-oncogene: Induction of cyclin A and enhanced CDK2 activity
-
DOI 10.1074/jbc.M310184200
-
Sunters, A., Thomas, D. P., Yeudall, W. A., and Grigoriadis, A. E. (2004) Accelerated cell cycle progression in osteoblasts overexpressing the c-fos proto-oncogene. Induction of cyclin A and enhanced CDK2 activity. J. Biol. Chem. 279, 9882-9891 (Pubitemid 38372587)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.11
, pp. 9882-9891
-
-
Sunters, A.1
Thomas, D.P.2
Yeudall, W.A.3
Grigoriadis, A.E.4
-
55
-
-
3242682602
-
Dual roles for NF-κB activation in osteoblastic cells by serum deprivation: Osteoblastic apoptosis and cell-cycle arrest
-
DOI 10.1016/j.bone.2004.03.003, PII S875632820400105X
-
Mogi, M., Ozeki, N., Nakamura, H., and Togari, A. (2004) Dual roles for NF-κB activation in osteoblastic cells by serum deprivation. Osteoblastic apoptosis and cell cycle arrest. Bone 35, 507-516 (Pubitemid 38953199)
-
(2004)
Bone
, vol.35
, Issue.2
, pp. 507-516
-
-
Mogi, M.1
Ozeki, N.2
Nakamura, H.3
Togari, A.4
-
56
-
-
77949488433
-
The influence of Pyk2 on the mechanical properties in fibroblasts
-
Klemm, A. H., Kienle, S., Rheinlaender, J., Schäffer, T. E., and Goldmann, W. H. (2010) The influence of Pyk2 on the mechanical properties in fibroblasts. Biochem. Biophys. Res. Commun. 393, 694-697
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.393
, pp. 694-697
-
-
Klemm, A.H.1
Kienle, S.2
Rheinlaender, J.3
Schäffer, T.E.4
Goldmann, W.H.5
-
57
-
-
0033731010
-
Focal adhesion kinase suppresses Rho activity to promote focal adhesion turnover
-
Ren, X. D., Kiosses, W. B., Sieg, D. J., Otey, C. A., Schlaepfer, D. D., and Schwartz, M. A. (2000) Focal adhesion kinase suppresses Rho activity to promote focal adhesion turnover. J. Cell Sci. 113, 3673-3678
-
(2000)
J. Cell Sci.
, vol.113
, pp. 3673-3678
-
-
Ren, X.D.1
Kiosses, W.B.2
Sieg, D.J.3
Otey, C.A.4
Schlaepfer, D.D.5
Schwartz, M.A.6
-
58
-
-
0028289263
-
Concentration-dependent effects of cytochalasin D on tight junctions and actin filaments in MDCK epithelial cells
-
Stevenson, B. R., and Begg, D. A. (1994) Concentration-dependent effects of cytochalasin D on tight junctions and actin filaments in MDCK epithelial cells. J. Cell Sci. 107, 367-375 (Pubitemid 24091844)
-
(1994)
Journal of Cell Science
, vol.107
, Issue.3
, pp. 367-375
-
-
Stevenson, B.R.1
Begg, D.A.2
-
59
-
-
0036257483
-
Nuclear translocation of cell adhesion kinase β/proline-rich tyrosine kinase 2
-
DOI 10.1247/csf.27.47
-
Aoto, H., Sasaki, H., Ishino, M., and Sasaki, T. (2002) Nuclear translocation of cell adhesion kinase β/proline-rich tyrosine kinase 2. Cell Struct. Funct. 27, 47-61 (Pubitemid 34498354)
-
(2002)
Cell Structure and Function
, vol.27
, Issue.1
, pp. 47-61
-
-
Aoto, H.1
Sasaki, H.2
Ishino, M.3
Sasaki, T.4
-
60
-
-
0036644069
-
TCR engagement induces proline-rich tyrosine kinase-2 (Pyk2) translocation to the T cell-APC interface independently of Pyk2 activity and in an immunoreceptor tyrosine-based activation motif-mediated fashion
-
Sancho, D., Montoya, M. C., Monjas, A., Gordón-Alonso, M., Katagiri, T., Gil, D., Tejedor, R., Alarcón, B., and Sánchez- Madrid, F. (2002) TCR engagement induces proline-rich tyrosine kinase-2 (Pyk2) translocation to the T cell-APC interface independently of Pyk2 activity and in an immunoreceptor tyrosine-based activation motif-mediated fashion. J. Immunol. 169, 292-300 (Pubitemid 34686148)
-
(2002)
Journal of Immunology
, vol.169
, Issue.1
, pp. 292-300
-
-
Sancho, D.1
Montoya, M.C.2
Monjas, A.3
Gordon-Alonso, M.4
Katagiri, T.5
Gil, D.6
Tejedor, R.7
Alarcon, B.8
Sanchez-Madrid, F.9
-
61
-
-
34948882316
-
Calcineurin is essential for depolarization-induced nuclear translocation and tyrosine phosphorylation of PYK2 in neurons
-
DOI 10.1242/jcs.009613
-
Faure, C., Corvol, J. C., Toutant, M., Valjent, E., Hvalby, O., Jensen, V., El Messari, S., Corsi, J. M., Kadaré, G., and Girault, J. A. (2007) Calcineurin is essential for depolarization-induced nuclear translocation and tyrosine phosphorylation of PYK2 in neurons. J. Cell Sci. 120, 3034-3044 (Pubitemid 47517086)
-
(2007)
Journal of Cell Science
, vol.120
, Issue.17
, pp. 3034-3044
-
-
Faure, C.1
Corvol, J.-C.2
Toutant, M.3
Valjent, E.4
Hvalby, O.5
Jensen, V.6
El, M.S.7
Corsi, J.-M.8
Kadare, G.9
Girault, J.-A.10
-
62
-
-
0037035519
-
Connexin family members target to lipid raft domains and interact with caveolin-1
-
DOI 10.1021/bi0121656
-
Schubert, A. L., Schubert, W., Spray, D. C., and Lisanti, M. P. (2002) Connexin family members target to lipid raft domains and interact with caveolin-1. Biochemistry 41, 5754-5764 (Pubitemid 34462696)
-
(2002)
Biochemistry
, vol.41
, Issue.18
, pp. 5754-5764
-
-
Schubert, A.-L.1
Schubert, W.2
Spray, D.C.3
Lisanti, M.P.4
-
63
-
-
41649104490
-
Caveolin-1 and -2 interact with connexin43 and regulate gap junctional intercellular communication in keratinocytes
-
DOI 10.1091/mbc.E07-06-0596
-
Langlois, S., Cowan, K. N., Shao, Q., Cowan, B. J., and Laird, D. W. (2008) Caveolin-1 and -2 interact with connexin43 and regulate gap junctional intercellular communication in keratinocytes. Mol. Biol. Cell 19, 912-928 (Pubitemid 351481808)
-
(2008)
Molecular Biology of the Cell
, vol.19
, Issue.3
, pp. 912-928
-
-
Langlois, S.1
Cowan, K.N.2
Shao, Q.3
Cowan, B.J.4
Laird, D.W.5
-
64
-
-
0035933764
-
Connexin45 interacts with zonula occludens-1 and connexin43 in osteoblastic cells
-
Laing, J. G., Manley-Markowski, R. N., Koval, M., Civitelli, R., and Steinberg, T. H. (2001) Connexin45 interacts with zonula occludens-1 and connexin43 in osteoblastic cells. J. Biol. Chem. 276, 23051-23055
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 23051-23055
-
-
Laing, J.G.1
Manley-Markowski, R.N.2
Koval, M.3
Civitelli, R.4
Steinberg, T.H.5
-
65
-
-
0035750784
-
Connexin45 interacts with zonula occludens-1 in osteoblastic cells
-
Laing, J. G., Manley-Markowski, R. N., Koval, M., Civitelli, R., and Steinberg, T. H. (2001) Connexin45 interacts with zonula occludens-1 in osteoblastic cells. Cell Commun. Adhes. 8, 209-212
-
(2001)
Cell Commun. Adhes.
, vol.8
, pp. 209-212
-
-
Laing, J.G.1
Manley-Markowski, R.N.2
Koval, M.3
Civitelli, R.4
Steinberg, T.H.5
-
66
-
-
0032486285
-
Identification of a new Pyk2 isoform implicated in chemokine and antigen receptor signaling
-
DOI 10.1074/jbc.273.23.14301
-
Dikic, I., Dikic, I., and Schlessinger, J. (1998) Identification of a new Pyk2 isoform implicated in chemokine and antigen receptor signaling. J. Biol. Chem. 273, 14301-14308 (Pubitemid 28319145)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.23
, pp. 14301-14308
-
-
Dikic, I.1
Dikic, I.2
Schlessinger, J.3
-
67
-
-
0036297147
-
Human endothelial Pyk2 is expressed in two isoforms and associates with paxillin and p130Cas
-
DOI 10.1006/bbrc.2002.6350
-
Keogh, R. J., Houliston, R. A., and Wheeler-Jones, C. P. (2002) Human endothelial Pyk2 is expressed in two isoforms and associates with paxillin and p130Cas. Biochem. Biophys. Res. Commun. 290, 1470-1477 (Pubitemid 34687423)
-
(2002)
Biochemical and Biophysical Research Communications
, vol.290
, Issue.5
, pp. 1470-1477
-
-
Keogh, R.J.1
Houliston, R.A.2
Wheeler-Jones, C.P.D.3
|