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Volumn 230, Issue 3, 2015, Pages 578-586

Signaling pathways involved in megakaryocyte-mediated proliferation of osteoblast lineage cells

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; SYNAPTOPHYSIN; MDM2 PROTEIN, HUMAN; PROTEIN MDM2;

EID: 84920933828     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.24774     Document Type: Article
Times cited : (13)

References (67)
  • 1
    • 53349141349 scopus 로고    scopus 로고
    • The retinoblastoma protein tumor suppressor is important for appropriate osteoblast differentiation and bone development
    • Berman SD, Yuan TL, Miller ES, Lee EY, Caron A, Lees JA. 2008. The retinoblastoma protein tumor suppressor is important for appropriate osteoblast differentiation and bone development. Mol Cancer Res 6:1440-1451.
    • (2008) Mol Cancer Res , vol.6 , pp. 1440-1451
    • Berman, S.D.1    Yuan, T.L.2    Miller, E.S.3    Lee, E.Y.4    Caron, A.5    Lees, J.A.6
  • 3
    • 0025784444 scopus 로고
    • Glucocorticoid regulation of transforming growth factor beta 1 activity and binding in osteoblast-enriched cultures from fetal rat bone
    • Centrella M, McCarthy TL, Canalis E. 1991. Glucocorticoid regulation of transforming growth factor beta 1 activity and binding in osteoblast-enriched cultures from fetal rat bone. Mol Cell Biol 11:4490-4496.
    • (1991) Mol Cell Biol , vol.11 , pp. 4490-4496
    • Centrella, M.1    McCarthy, T.L.2    Canalis, E.3
  • 4
    • 33745081542 scopus 로고    scopus 로고
    • Pathogenesis of myelofibrosis with myeloid metaplasia: Insight from mouse models
    • Chagraoui H, Wendling F, Vainchenker W. 2006. Pathogenesis of myelofibrosis with myeloid metaplasia: Insight from mouse models. Best Pract Res Clin Haematol 19:399-412.
    • (2006) Best Pract Res Clin Haematol , vol.19 , pp. 399-412
    • Chagraoui, H.1    Wendling, F.2    Vainchenker, W.3
  • 5
    • 0025905183 scopus 로고
    • The E2F transcription factor is a cellular target for the RB protein
    • Chellappan SP, Hiebert S, Mudryj M, Horowitz JM, Nevins JR. 1991. The E2F transcription factor is a cellular target for the RB protein. Cell 65:1053-1061.
    • (1991) Cell , vol.65 , pp. 1053-1061
    • Chellappan, S.P.1    Hiebert, S.2    Mudryj, M.3    Horowitz, J.M.4    Nevins, J.R.5
  • 6
    • 0029171789 scopus 로고
    • Regulation of transcription functions of the p53 tumor suppressor by the mdm-2 oncogene
    • Chen J, Lin J, Levine AJ. 1995. Regulation of transcription functions of the p53 tumor suppressor by the mdm-2 oncogene. Mol Med 1:142-152.
    • (1995) Mol Med , vol.1 , pp. 142-152
    • Chen, J.1    Lin, J.2    Levine, A.J.3
  • 7
    • 0034038046 scopus 로고    scopus 로고
    • Human mesenchymal stem cells support megakaryocyte and pro-platelet formation from CD34(+) hematopoietic progenitor cells
    • Cheng L, Qasba P, Vanguri P, Thiede MA. 2000. Human mesenchymal stem cells support megakaryocyte and pro-platelet formation from CD34(+) hematopoietic progenitor cells. J Cell Physiol 184:58-69.
    • (2000) J Cell Physiol , vol.184 , pp. 58-69
    • Cheng, L.1    Qasba, P.2    Vanguri, P.3    Thiede, M.A.4
  • 9
    • 77749309917 scopus 로고    scopus 로고
    • Immature and mature megakaryocytes enhance osteoblast proliferation and inhibit osteoclast formation
    • Ciovacco WA, Cheng YH, Horowitz MC, Kacena MA. 2010. Immature and mature megakaryocytes enhance osteoblast proliferation and inhibit osteoclast formation. J Cell Biochem 109:774-781.
    • (2010) J Cell Biochem , vol.109 , pp. 774-781
    • Ciovacco, W.A.1    Cheng, Y.H.2    Horowitz, M.C.3    Kacena, M.A.4
  • 13
    • 0031028065 scopus 로고    scopus 로고
    • Thrombopoietin signal transduction in purified murine megakaryocytes
    • Drachman JG, Sabath DF, Fox NE, Kaushansky K. 1997. Thrombopoietin signal transduction in purified murine megakaryocytes. Blood 89:483-492.
    • (1997) Blood , vol.89 , pp. 483-492
    • Drachman, J.G.1    Sabath, D.F.2    Fox, N.E.3    Kaushansky, K.4
  • 14
    • 0031724593 scopus 로고    scopus 로고
    • Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6
    • Freedman DA, Levine AJ. 1998. Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6. Mol Cell Biol 18:7288-7293.
    • (1998) Mol Cell Biol , vol.18 , pp. 7288-7293
    • Freedman, D.A.1    Levine, A.J.2
  • 15
    • 0032541906 scopus 로고    scopus 로고
    • Adenovirus long-term expression of thrombopoietin in vivo: a new model for myeloproliferative syndrome and osteomyelofibrosis
    • Frey BM, Rafii S, Crystal RG, Moore MA. 1998a. Adenovirus long-term expression of thrombopoietin in vivo: a new model for myeloproliferative syndrome and osteomyelofibrosis. Schweiz Med Wochenschr 128:1587-1592.
    • (1998) Schweiz Med Wochenschr , vol.128 , pp. 1587-1592
    • Frey, B.M.1    Rafii, S.2    Crystal, R.G.3    Moore, M.A.4
  • 16
    • 0031963996 scopus 로고    scopus 로고
    • Adenovector-mediated expression of human thrombopoietin cDNA in immune-compromised mice: insights into the pathophysiology of osteomyelofibrosis
    • Frey BM, Rafii S, Teterson M, Eaton D, Crystal RG, Moore MA. 1998b. Adenovector-mediated expression of human thrombopoietin cDNA in immune-compromised mice: insights into the pathophysiology of osteomyelofibrosis. J Immunol 160:691-699.
    • (1998) J Immunol , vol.160 , pp. 691-699
    • Frey, B.M.1    Rafii, S.2    Teterson, M.3    Eaton, D.4    Crystal, R.G.5    Moore, M.A.6
  • 17
    • 69449085360 scopus 로고    scopus 로고
    • MDM2 controls the timely expression of cyclin A to regulate the cell cycle
    • Frum R, Ramamoorthy M, Mohanraj L, Deb S, Deb SP. 2009. MDM2 controls the timely expression of cyclin A to regulate the cell cycle. Mol Cancer Res 7:1253-1267.
    • (2009) Mol Cancer Res , vol.7 , pp. 1253-1267
    • Frum, R.1    Ramamoorthy, M.2    Mohanraj, L.3    Deb, S.4    Deb, S.P.5
  • 18
    • 0034282220 scopus 로고    scopus 로고
    • The MDM2 RING-finger domain is required to promote p53 nuclear export
    • Geyer RK, Yu ZK, Maki CG. 2000. The MDM2 RING-finger domain is required to promote p53 nuclear export. Nat Cell Biol 2:569-573.
    • (2000) Nat Cell Biol , vol.2 , pp. 569-573
    • Geyer, R.K.1    Yu, Z.K.2    Maki, C.G.3
  • 19
    • 0029328352 scopus 로고
    • Regulated expression of the retinoblastoma susceptibility gene in mammary carcinoma cells restores cyclin D1 expression and G1-phase control
    • Gjetting T, Lukas J, Bartek J, Strauss M. 1995. Regulated expression of the retinoblastoma susceptibility gene in mammary carcinoma cells restores cyclin D1 expression and G1-phase control. Biol Chem Hoppe Seyler 376:441-446.
    • (1995) Biol Chem Hoppe Seyler , vol.376 , pp. 441-446
    • Gjetting, T.1    Lukas, J.2    Bartek, J.3    Strauss, M.4
  • 20
    • 0026489470 scopus 로고
    • Abrogation by c-myc of G1 phase arrest induced by RB protein but not by p53
    • Goodrich DW, Lee WH. 1992. Abrogation by c-myc of G1 phase arrest induced by RB protein but not by p53. Nature 360:177-179.
    • (1992) Nature , vol.360 , pp. 177-179
    • Goodrich, D.W.1    Lee, W.H.2
  • 21
    • 0026058874 scopus 로고
    • The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle
    • Goodrich DW, Wang NP, Qian YW, Lee EY, Lee WH. 1991. The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle. Cell 67:293-302.
    • (1991) Cell , vol.67 , pp. 293-302
    • Goodrich, D.W.1    Wang, N.P.2    Qian, Y.W.3    Lee, E.Y.4    Lee, W.H.5
  • 22
    • 0028568315 scopus 로고
    • Cell cycle control and cancer
    • Hartwell LH, Kastan MB. 1994. Cell cycle control and cancer. Science 266:1821-1828.
    • (1994) Science , vol.266 , pp. 1821-1828
    • Hartwell, L.H.1    Kastan, M.B.2
  • 23
    • 0030905284 scopus 로고    scopus 로고
    • Mdm2 promotes the rapid degradation of p53
    • Haupt Y, Maya R, Kazaz A, Oren M. 1997. Mdm2 promotes the rapid degradation of p53. Nature 387:296-299.
    • (1997) Nature , vol.387 , pp. 296-299
    • Haupt, Y.1    Maya, R.2    Kazaz, A.3    Oren, M.4
  • 24
    • 0026802989 scopus 로고
    • Regulation of retinoblastoma protein functions by ectopic expression of human cyclins
    • Hinds PW, Mittnacht S, Dulic V, Arnold A, Reed SI, Weinberg RA. 1992. Regulation of retinoblastoma protein functions by ectopic expression of human cyclins. Cell 70:993-1006.
    • (1992) Cell , vol.70 , pp. 993-1006
    • Hinds, P.W.1    Mittnacht, S.2    Dulic, V.3    Arnold, A.4    Reed, S.I.5    Weinberg, R.A.6
  • 25
    • 0027582453 scopus 로고
    • Integration of cell cycle control with transcriptional regulation by the retinoblastoma protein
    • Hollingsworth RE, Jr., Chen PL, Lee WH. 1993a. Integration of cell cycle control with transcriptional regulation by the retinoblastoma protein. Curr Opin Cell Biol 5:194-200.
    • (1993) Curr Opin Cell Biol , vol.5 , pp. 194-200
    • Hollingsworth Jr, R.E.1    Chen, P.L.2    Lee, W.H.3
  • 27
    • 0031583962 scopus 로고    scopus 로고
    • Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53
    • Honda R, Tanaka H, Yasuda H. 1997. Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53. FEBS Lett 420:25-27.
    • (1997) FEBS Lett , vol.420 , pp. 25-27
    • Honda, R.1    Tanaka, H.2    Yasuda, H.3
  • 31
    • 33745183341 scopus 로고    scopus 로고
    • Hdm2 nuclear export, regulated by insulin-like growth factor-I/MAPK/p90Rsk signaling, mediates the transformation of human cells
    • Jackson MW, Patt LE, LaRusch GA, Donner DB, Stark GR, Mayo LD. 2006. Hdm2 nuclear export, regulated by insulin-like growth factor-I/MAPK/p90Rsk signaling, mediates the transformation of human cells. J Biol Chem 281:16814-16820.
    • (2006) J Biol Chem , vol.281 , pp. 16814-16820
    • Jackson, M.W.1    Patt, L.E.2    LaRusch, G.A.3    Donner, D.B.4    Stark, G.R.5    Mayo, L.D.6
  • 32
    • 0019407729 scopus 로고
    • Role of phosphodiesterase in the parathormone-stimulated adenosine 3',5'-monophosphate response in bone cell populations enriched in osteoclasts and osteoblasts
    • Jilka RL, Cohn DV. 1981. Role of phosphodiesterase in the parathormone-stimulated adenosine 3', 5'-monophosphate response in bone cell populations enriched in osteoclasts and osteoblasts. Endocrinology 109:743-747.
    • (1981) Endocrinology , vol.109 , pp. 743-747
    • Jilka, R.L.1    Cohn, D.V.2
  • 34
    • 14144251106 scopus 로고    scopus 로고
    • Loss of the transcription factor p45 NF-E2 results in a developmental arrest of megakaryocyte differentiation and the onset of a high bone mass phenotype
    • Kacena MA, Gundberg CM, Nelson T, Horowitz MC. 2005. Loss of the transcription factor p45 NF-E2 results in a developmental arrest of megakaryocyte differentiation and the onset of a high bone mass phenotype. Bone 36:215-223.
    • (2005) Bone , vol.36 , pp. 215-223
    • Kacena, M.A.1    Gundberg, C.M.2    Nelson, T.3    Horowitz, M.C.4
  • 37
  • 38
    • 77950385868 scopus 로고    scopus 로고
    • Involvement of integrins alpha(3) beta(1) and alpha(5) beta(1) and glycoprotein IIb in megakaryocyte-induced osteoblast proliferation
    • Lemieux JM, Horowitz MC, Kacena MA. 2010. Involvement of integrins alpha(3) beta(1) and alpha(5) beta(1) and glycoprotein IIb in megakaryocyte-induced osteoblast proliferation. J Cell Biochem 109:927-932.
    • (2010) J Cell Biochem , vol.109 , pp. 927-932
    • Lemieux, J.M.1    Horowitz, M.C.2    Kacena, M.A.3
  • 40
    • 1842378642 scopus 로고    scopus 로고
    • The MDM2 C-terminal region binds to TAFII250 and is required for MDM2 regulation of the cyclin A promoter
    • Leveillard T, Wasylyk B. 1997. The MDM2 C-terminal region binds to TAFII250 and is required for MDM2 regulation of the cyclin A promoter. J Biol Chem 272:30651-30661.
    • (1997) J Biol Chem , vol.272 , pp. 30651-30661
    • Leveillard, T.1    Wasylyk, B.2
  • 41
    • 0026649648 scopus 로고
    • The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
    • Momand J, Zambetti GP, Olson DC, George D, Levine AJ. 1992. The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell 69:1237-1245.
    • (1992) Cell , vol.69 , pp. 1237-1245
    • Momand, J.1    Zambetti, G.P.2    Olson, D.C.3    George, D.4    Levine, A.J.5
  • 42
    • 0016513823 scopus 로고
    • Patho-anatomical features of the bone marrow
    • Lennert K, Nagai K, Schwarze EW. 1975. Patho-anatomical features of the bone marrow. Clin Haematol 4:331-351.
    • (1975) Clin Haematol , vol.4 , pp. 331-351
    • Lennert, K.1    Nagai, K.2    Schwarze, E.W.3
  • 43
    • 0348134742 scopus 로고    scopus 로고
    • Mono- versus polyubiquitination: differential control of p53 fate by Mdm2
    • Li M, Brooks CL, Wu-Baer F, Chen D, Baer R, Gu W. 2003. Mono- versus polyubiquitination: differential control of p53 fate by Mdm2. Science 302:1972-1975.
    • (2003) Science , vol.302 , pp. 1972-1975
    • Li, M.1    Brooks, C.L.2    Wu-Baer, F.3    Chen, D.4    Baer, R.5    Gu, W.6
  • 44
    • 0035949588 scopus 로고    scopus 로고
    • A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus
    • Mayo LD, Donner DB. 2001. A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus. Proc Natl Acad Sci U S A 98:11598-11603.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 11598-11603
    • Mayo, L.D.1    Donner, D.B.2
  • 46
    • 3042734108 scopus 로고    scopus 로고
    • Megakaryocyte-bone marrow stromal cell aggregates demonstrate increased colony formation and alkaline phosphatase expression in vitro
    • Miao D, Murant S, Scutt N, Genever P, Scutt A. 2004. Megakaryocyte-bone marrow stromal cell aggregates demonstrate increased colony formation and alkaline phosphatase expression in vitro. Tissue Eng 10:807-817.
    • (2004) Tissue Eng , vol.10 , pp. 807-817
    • Miao, D.1    Murant, S.2    Scutt, N.3    Genever, P.4    Scutt, A.5
  • 47
    • 84883571576 scopus 로고    scopus 로고
    • Megakaryocytes promote murine osteoblastic HSC niche expansion and stem cell engraftment after radioablative conditioning
    • Olson TS, Caselli A, Otsuru S, Hofmann TJ, Williams R, Paolucci P, Dominici M, Horwitz EM. 2013. Megakaryocytes promote murine osteoblastic HSC niche expansion and stem cell engraftment after radioablative conditioning. Blood 121:5238-5249.
    • (2013) Blood , vol.121 , pp. 5238-5249
    • Olson, T.S.1    Caselli, A.2    Otsuru, S.3    Hofmann, T.J.4    Williams, R.5    Paolucci, P.6    Dominici, M.7    Horwitz, E.M.8
  • 48
    • 0038342441 scopus 로고    scopus 로고
    • Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry
    • Sage J, Miller AL, Perez-Mancera PA, Wysocki JM, Jacks T. 2003. Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry. Nature 424:223-228.
    • (2003) Nature , vol.424 , pp. 223-228
    • Sage, J.1    Miller, A.L.2    Perez-Mancera, P.A.3    Wysocki, J.M.4    Jacks, T.5
  • 49
    • 28444437051 scopus 로고    scopus 로고
    • MDM2 promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma protein
    • Sdek P, Ying H, Chang DL, Qiu W, Zheng H, Touitou R, Allday MJ, Xiao ZX. 2005. MDM2 promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma protein. Mol Cell 20:699-708.
    • (2005) Mol Cell , vol.20 , pp. 699-708
    • Sdek, P.1    Ying, H.2    Chang, D.L.3    Qiu, W.4    Zheng, H.5    Touitou, R.6    Allday, M.J.7    Xiao, Z.X.8
  • 50
    • 11144241617 scopus 로고    scopus 로고
    • The central acidic domain of MDM2 is critical in inhibition of retinoblastoma-mediated suppression of E2F and cell growth
    • Sdek P, Ying H, Zheng H, Margulis A, Tang X, Tian K, Xiao ZX. 2004. The central acidic domain of MDM2 is critical in inhibition of retinoblastoma-mediated suppression of E2F and cell growth. J Biol Chem 279:53317-53322.
    • (2004) J Biol Chem , vol.279 , pp. 53317-53322
    • Sdek, P.1    Ying, H.2    Zheng, H.3    Margulis, A.4    Tang, X.5    Tian, K.6    Xiao, Z.X.7
  • 51
    • 0030926006 scopus 로고    scopus 로고
    • A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development
    • Shivdasani RA, Fujiwara Y, McDevitt MA, Orkin SH. 1997. A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development. EMBO J 16:3965-3973.
    • (1997) EMBO J , vol.16 , pp. 3965-3973
    • Shivdasani, R.A.1    Fujiwara, Y.2    McDevitt, M.A.3    Orkin, S.H.4
  • 52
    • 0029051295 scopus 로고
    • Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development
    • Shivdasani RA, Rosenblatt MF, Zucker-Franklin D, Jackson CW, Hunt P, Saris CJ, Orkin SH. 1995. Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development. Cell 81:695-704.
    • (1995) Cell , vol.81 , pp. 695-704
    • Shivdasani, R.A.1    Rosenblatt, M.F.2    Zucker-Franklin, D.3    Jackson, C.W.4    Hunt, P.5    Saris, C.J.6    Orkin, S.H.7
  • 54
    • 0026599286 scopus 로고
    • Relationship between cytokine-dependent cell cycle progression and MHC class II antigen expression by human CD34+ HLA-DR- bone marrow cells
    • Srour EF, Brandt JE, Leemhuis T, Ballas CB, Hoffman R. 1992. Relationship between cytokine-dependent cell cycle progression and MHC class II antigen expression by human CD34+ HLA-DR- bone marrow cells. J Immunol 148:815-820.
    • (1992) J Immunol , vol.148 , pp. 815-820
    • Srour, E.F.1    Brandt, J.E.2    Leemhuis, T.3    Ballas, C.B.4    Hoffman, R.5
  • 56
    • 0032757399 scopus 로고    scopus 로고
    • Histochemistry and morphometry on bone marrow biopsies in chronic myeloproliferative disorders - aids to diagnosis and classification
    • Thiele J, Kvasnicka HM, Fischer R. 1999. Histochemistry and morphometry on bone marrow biopsies in chronic myeloproliferative disorders - aids to diagnosis and classification. Ann Hematol 78:495-506.
    • (1999) Ann Hematol , vol.78 , pp. 495-506
    • Thiele, J.1    Kvasnicka, H.M.2    Fischer, R.3
  • 57
    • 1042297114 scopus 로고    scopus 로고
    • Use of cultured osteoblastic cells to identify and characterize transcriptional regulatory complexes
    • In: Bilezikian JP Raisz LG Rodan GA, editor. . San Diego, CA: Academic Press. pp -.
    • Towler DA, St. Aarnaud R. 2002. Use of cultured osteoblastic cells to identify and characterize transcriptional regulatory complexes. In: Bilezikian JP Raisz LG Rodan GA, editor. Principles of bone biology. San Diego, CA: Academic Press. pp 1503-1527.
    • (2002) Principles of bone biology , pp. 1503-1527
    • Towler, D.A.1    Aarnaud, R.2
  • 61
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • Weinberg RA. 1995. The retinoblastoma protein and cell cycle control. Cell 81:323-330.
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 62
    • 0016820226 scopus 로고
    • Target cells in bone for parathormone and calcitonin are different: enrichment for each cell type by sequential digestion of mouse calvaria and selective adhesion to polymeric surfaces
    • Wong GL, Cohn DV. 1975. Target cells in bone for parathormone and calcitonin are different: enrichment for each cell type by sequential digestion of mouse calvaria and selective adhesion to polymeric surfaces. Proc Natl Acad Sci U S A 72:3167-3171.
    • (1975) Proc Natl Acad Sci U S A , vol.72 , pp. 3167-3171
    • Wong, G.L.1    Cohn, D.V.2
  • 64
    • 3142570737 scopus 로고    scopus 로고
    • Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity
    • Xirodimas DP, Saville MK, Bourdon JC, Hay RT, Lane DP. 2004. Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity. Cell 118:83-97.
    • (2004) Cell , vol.118 , pp. 83-97
    • Xirodimas, D.P.1    Saville, M.K.2    Bourdon, J.C.3    Hay, R.T.4    Lane, D.P.5
  • 66
    • 0029956149 scopus 로고    scopus 로고
    • A model of myelofibrosis and osteosclerosis in mice induced by overexpressing thrombopoietin (mpl ligand): reversal of disease by bone marrow transplantation
    • Yan XQ, Lacey D, Hill D, Chen Y, Fletcher F, Hawley RG, McNiece IK. 1996. A model of myelofibrosis and osteosclerosis in mice induced by overexpressing thrombopoietin (mpl ligand): reversal of disease by bone marrow transplantation. Blood 88:402-409.
    • (1996) Blood , vol.88 , pp. 402-409
    • Yan, X.Q.1    Lacey, D.2    Hill, D.3    Chen, Y.4    Fletcher, F.5    Hawley, R.G.6    McNiece, I.K.7
  • 67
    • 33644770294 scopus 로고    scopus 로고
    • Targeting retinoblastoma protein for degradation by proteasomes
    • Ying H, Xiao ZX. 2006. Targeting retinoblastoma protein for degradation by proteasomes. Cell Cycle 5:506-508.
    • (2006) Cell Cycle , vol.5 , pp. 506-508
    • Ying, H.1    Xiao, Z.X.2


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