-
1
-
-
63849300402
-
Common variants of four bilirubin metabolism genes and their association with serum bilirubin and coronary artery disease in Chinese Han population
-
Lin R, Wang Y, Wang Y, et al. Common variants of four bilirubin metabolism genes and their association with serum bilirubin and coronary artery disease in Chinese Han population. Pharmacogenet Genomics 2009;19: 310-318
-
(2009)
Pharmacogenet Genomics
, vol.19
, pp. 310-318
-
-
Lin, R.1
Wang, Y.2
Wang, Y.3
-
2
-
-
84864101453
-
High total bilirubin as a protective factor for diabetes mellitus: An analysis of NHANES data from 1999 -2006
-
Cheriyath P, Gorrepati VS, Peters I, et al. High total bilirubin as a protective factor for diabetes mellitus: An analysis of NHANES data from 1999 -2006. J Clin Med Res 2010;2: 201-206
-
(2010)
J Clin Med Res
, vol.2
, pp. 201-206
-
-
Cheriyath, P.1
Gorrepati, V.S.2
Peters, I.3
-
3
-
-
79960919313
-
Biliverdin protects against the deterioration of glucose tolerance in db/db mice
-
Ikeda N, Inoguchi T, Sonoda N, et al. Biliverdin protects against the deterioration of glucose tolerance in db/db mice. Diabetologia 2011;54: 2183-2191
-
(2011)
Diabetologia
, vol.54
, pp. 2183-2191
-
-
Ikeda, N.1
Inoguchi, T.2
Sonoda, N.3
-
4
-
-
84870251882
-
Cardiovascular events as a function of serum bilirubin levels in a large, statin-treated cohort
-
Horsfall LJ, Nazareth I, Petersen I. Cardiovascular events as a function of serum bilirubin levels in a large, statin-treated cohort. Circulation 2012;126: 2556-2564
-
(2012)
Circulation
, vol.126
, pp. 2556-2564
-
-
Horsfall, L.J.1
Nazareth, I.2
Petersen, I.3
-
5
-
-
33749524440
-
Association between the UGT1A1∗28 allele, bilirubin levels, and coronary heart disease in the Framingham Heart Study
-
Lin JP, O'Donnell CJ, Schwaiger JP, et al. Association between the UGT1A1∗28 allele, bilirubin levels, and coronary heart disease in the Framingham Heart Study. Circulation 2006;114: 1476-1481
-
(2006)
Circulation
, vol.114
, pp. 1476-1481
-
-
Lin, J.P.1
O'Donnell, C.J.2
Schwaiger, J.P.3
-
6
-
-
84879552117
-
Serum bilirubin levels are lower in overweight asymptomatic middle-aged adults: An early indicator of metabolic syndrome?
-
Jenko-Pražnikar Z, Petelin A, Jurdana M, Žiberna L. Serum bilirubin levels are lower in overweight asymptomatic middle-aged adults: An early indicator of metabolic syndrome? Metabolism 2013;62: 976-985
-
(2013)
Metabolism
, vol.62
, pp. 976-985
-
-
Jenko-Pražnikar, Z.1
Petelin, A.2
Jurdana, M.3
Žiberna, L.4
-
7
-
-
69449086530
-
GEC-targeted HO-1 expression reduces proteinuria in glomerular immune injury
-
Duann P, Lianos EA. GEC-targeted HO-1 expression reduces proteinuria in glomerular immune injury. Am J Physiol Renal Physiol 2009;297: F629-F638
-
(2009)
Am J Physiol Renal Physiol
, vol.297
, pp. F629-F638
-
-
Duann, P.1
Lianos, E.A.2
-
8
-
-
34247615614
-
Heme oxygenase -1 gene therapy: Recent advances and therapeutic applications
-
Abraham NG, Asija A, Drummond G, Peterson S. Heme oxygenase -1 gene therapy: Recent advances and therapeutic applications. Curr Gene Ther 2007;7: 89-108
-
(2007)
Curr Gene Ther
, vol.7
, pp. 89-108
-
-
Abraham, N.G.1
Asija, A.2
Drummond, G.3
Peterson, S.4
-
10
-
-
0023132858
-
Bilirubin is an antioxidant of possible physiological importance
-
Stocker R, Yamamoto Y, McDonagh AF, Glazer AN, Ames BN. Bilirubin is an antioxidant of possible physiological importance. Science 1987;235: 1043-1046
-
(1987)
Science
, vol.235
, pp. 1043-1046
-
-
Stocker, R.1
Yamamoto, Y.2
McDonagh, A.F.3
Glazer, A.N.4
Ames, B.N.5
-
11
-
-
3342967615
-
Does bilirubin protect against hemochromatosis gene (HFE) related mortality?
-
Alizadeh BZ, Njajou OT, Houwing-Duistermaat JJ, et al. Does bilirubin protect against hemochromatosis gene (HFE) related mortality? Am J Med Genet A 2004;129A: 39-43
-
(2004)
Am J Med Genet A
, vol.129 A
, pp. 39-43
-
-
Alizadeh, B.Z.1
Njajou, O.T.2
Houwing-Duistermaat, J.J.3
-
12
-
-
0028882612
-
Low serum cholesterol and mortality. Which is the cause and which is the effect?
-
Iribarren C, Reed DM, Chen R, Yano K, Dwyer JH. Low serum cholesterol and mortality. Which is the cause and which is the effect? Circulation 1995;92: 2396-2403
-
(1995)
Circulation
, vol.92
, pp. 2396-2403
-
-
Iribarren, C.1
Reed, D.M.2
Chen, R.3
Yano, K.4
Dwyer, J.H.5
-
13
-
-
67049137261
-
Mendelian randomization: Nature's randomized trial in the post-genome era
-
Thanassoulis G, O'Donnell CJ. Mendelian randomization: Nature's randomized trial in the post-genome era. JAMA 2009;301: 2386-2388
-
(2009)
JAMA
, vol.301
, pp. 2386-2388
-
-
Thanassoulis, G.1
O'Donnell, C.J.2
-
14
-
-
40849083720
-
Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology
-
Lawlor DA, Harbord RM, Sterne JA, Timpson N, Davey Smith G. Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology. Stat Med 2008;27: 1133-1163
-
(2008)
Stat Med
, vol.27
, pp. 1133-1163
-
-
Lawlor, D.A.1
Harbord, R.M.2
Sterne, J.A.3
Timpson, N.4
Davey Smith, G.5
-
15
-
-
78649705083
-
Loci from a genome-wide analysis of bilirubin levels are associated with gallstone risk and composition
-
Buch S, Schafmayer C, Völzke H, et al. Loci from a genome-wide analysis of bilirubin levels are associated with gallstone risk and composition. Gastroenterology 2010;139: 1942-1951
-
(2010)
Gastroenterology
, vol.139
, pp. 1942-1951
-
-
Buch, S.1
Schafmayer, C.2
Völzke, H.3
-
16
-
-
77957735569
-
Serum bilirubin and genes controlling bilirubin concentrations as biomarkers for cardiovascular disease
-
Lin JP, Vitek L, Schwertner HA. Serum bilirubin and genes controlling bilirubin concentrations as biomarkers for cardiovascular disease. Clin Chem 2010; 56: 1535-1543
-
(2010)
Clin Chem
, vol.56
, pp. 1535-1543
-
-
Lin, J.P.1
Vitek, L.2
Schwertner, H.A.3
-
17
-
-
67649838598
-
Genome-wide association metaanalysis for total serum bilirubin levels
-
Johnson AD, Kavousi M, Smith AV, et al. Genome-wide association metaanalysis for total serum bilirubin levels. Hum Mol Genet 2009;18: 2700-2710
-
(2009)
Hum Mol Genet
, vol.18
, pp. 2700-2710
-
-
Johnson, A.D.1
Kavousi, M.2
Smith, A.V.3
-
18
-
-
53749086716
-
Albuminuria assessed from first-morningvoid urine samples versus 24-hour urine collections as a predictor of cardiovascular morbidity and mortality
-
Lambers Heerspink HJ, Brantsma AH, de Zeeuw D, Bakker SJ, de Jong PE, Gansevoort RT; PREVEND Study Group. Albuminuria assessed from first-morningvoid urine samples versus 24-hour urine collections as a predictor of cardiovascular morbidity and mortality. Am J Epidemiol 2008;168: 897-905
-
(2008)
Am J Epidemiol
, vol.168
, pp. 897-905
-
-
Lambers Heerspink, H.J.1
Brantsma, A.H.2
De Zeeuw, D.3
Bakker, S.J.4
De Jong, P.E.5
Gansevoort, R.T.6
-
19
-
-
0036636030
-
Pharmacy data in epidemiological studies: An easy to obtain and reliable tool
-
PREVEND Study Group Prevention of REnal and Vascular ENT Stage Disease
-
Monster TB, Janssen WM, de Jong PE, de Jong-van den Berg LT; PREVEND Study Group Prevention of REnal and Vascular ENT Stage Disease. Pharmacy data in epidemiological studies: An easy to obtain and reliable tool. Pharmacoepidemiol Drug Saf 2002;11: 379-384
-
(2002)
Pharmacoepidemiol Drug Saf
, vol.11
, pp. 379-384
-
-
Monster, T.B.1
Janssen, W.M.2
De Jong, P.E.3
De Jong-Van Den Berg, L.T.4
-
20
-
-
84866362758
-
Sex differences in the association between plasma copeptin and incident type 2 diabetes: The Prevention of Renal and Vascular Endstage Disease (PREVEND) study
-
Abbasi A, Corpeleijn E, Meijer E, et al. Sex differences in the association between plasma copeptin and incident type 2 diabetes: The Prevention of Renal and Vascular Endstage Disease (PREVEND) study. Diabetologia 2012;55: 1963-1970
-
(2012)
Diabetologia
, vol.55
, pp. 1963-1970
-
-
Abbasi, A.1
Corpeleijn, E.2
Meijer, E.3
-
21
-
-
84866607803
-
Prediction models for risk of developing type 2 diabetes: Systematic literature search and independent external validation study
-
Abbasi A, Peelen LM, Corpeleijn E, et al. Prediction models for risk of developing type 2 diabetes: Systematic literature search and independent external validation study. BMJ 2012;345: E5900
-
(2012)
BMJ
, vol.345
, pp. e5900
-
-
Abbasi, A.1
Peelen, L.M.2
Corpeleijn, E.3
-
22
-
-
84874373995
-
Genome-wide association study on plasma levels of midregional-proadrenomedullin and C-terminal-proendothelin-1
-
Verweij N, Mahmud H, Mateo Leach I, et al. Genome-wide association study on plasma levels of midregional-proadrenomedullin and C-terminal-proendothelin-1. Hypertension 2013;61: 602-608
-
(2013)
Hypertension
, vol.61
, pp. 602-608
-
-
Verweij, N.1
Mahmud, H.2
Mateo Leach, I.3
-
23
-
-
84871771750
-
Genetically elevated bilirubin and risk of ischaemic heart disease: Three Mendelian randomization studies and a meta-analysis
-
Stender S, Frikke-Schmidt R, Nordestgaard BG, Grande P, Tybjaerg-Hansen A. Genetically elevated bilirubin and risk of ischaemic heart disease: Three Mendelian randomization studies and a meta-analysis. J Intern Med 2013;273: 59-68
-
(2013)
J Intern Med
, vol.273
, pp. 59-68
-
-
Stender, S.1
Frikke-Schmidt, R.2
Nordestgaard, B.G.3
Grande, P.4
Tybjaerg-Hansen, A.5
-
24
-
-
79958821064
-
Instrumental variable estimation of causal risk ratios and causal odds ratios in Mendelian randomization analyses
-
Palmer TM, Sterne JA, Harbord RM, et al. Instrumental variable estimation of causal risk ratios and causal odds ratios in Mendelian randomization analyses. Am J Epidemiol 2011;173: 1392-1403
-
(2011)
Am J Epidemiol
, vol.173
, pp. 1392-1403
-
-
Palmer, T.M.1
Sterne, J.A.2
Harbord, R.M.3
-
25
-
-
84902684375
-
Sample size and power calculations in Mendelian randomization with a single instrumental variable and a binary outcome
-
Burgess S. Sample size and power calculations in Mendelian randomization with a single instrumental variable and a binary outcome. Int J Epidemiol 2014; 43: 922-929
-
(2014)
Int J Epidemiol
, vol.43
, pp. 922-929
-
-
Burgess, S.1
-
26
-
-
84906673427
-
Pleiotropic effects of lipid genes on plasma glucose HbA1c and HOMA-IR levels
-
Li N, van der Sijde MR, Bakker SJ, et al.; LifeLines Cohort Study Group. Pleiotropic effects of lipid genes on plasma glucose, HbA1c, and HOMA-IR levels. Diabetes 2014;63: 3149-3158
-
(2014)
Diabetes
, vol.63
, pp. 3149-3158
-
-
Li, N.1
Van Der Sijde, M.R.2
Bakker, S.J.3
-
27
-
-
84885840876
-
Mendelian randomization analysis with multiple genetic variants using summarized data
-
Burgess S, Butterworth A, Thompson SG. Mendelian randomization analysis with multiple genetic variants using summarized data. Genet Epidemiol 2013;37: 658-665
-
(2013)
Genet Epidemiol
, vol.37
, pp. 658-665
-
-
Burgess, S.1
Butterworth, A.2
Thompson, S.G.3
-
28
-
-
84868337361
-
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
-
Wellcome Trust Case Control Consortium; Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC) Investigators; Genetic Investigation of ANthropometric Traits (GIANT) Consortium; Asian Genetic Epidemiology Network-Type 2 Diabetes (AGEN-T2D) Consortium; South Asian Type 2 Diabetes (SAT2D) Consortium; DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium
-
Morris AP, Voight BF, Teslovich TM, et al.; Wellcome Trust Case Control Consortium; Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC) Investigators; Genetic Investigation of ANthropometric Traits (GIANT) Consortium; Asian Genetic Epidemiology Network-Type 2 Diabetes (AGEN-T2D) Consortium; South Asian Type 2 Diabetes (SAT2D) Consortium; DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet 2012;44: 981-990
-
(2012)
Nat Genet
, vol.44
, pp. 981-990
-
-
Morris, A.P.1
Voight, B.F.2
Teslovich, T.M.3
-
29
-
-
75749086085
-
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
-
DIAGRAM Consortium; GIANT Consortium; Global BPgen Consortium; Anders Hamsten on behalf of Procardis Consortium; MAGIC Investigators
-
Dupuis J, Langenberg C, Prokopenko I, et al.; DIAGRAM Consortium; GIANT Consortium; Global BPgen Consortium; Anders Hamsten on behalf of Procardis Consortium; MAGIC Investigators. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet 2010;42: 105-116
-
(2010)
Nat Genet
, vol.42
, pp. 105-116
-
-
Dupuis, J.1
Langenberg, C.2
Prokopenko, I.3
-
30
-
-
84884736257
-
Use of allele scores as instrumental variables for Mendelian randomization
-
Burgess S, Thompson SG. Use of allele scores as instrumental variables for Mendelian randomization. Int J Epidemiol 2013;42: 1134-1144
-
(2013)
Int J Epidemiol
, vol.42
, pp. 1134-1144
-
-
Burgess, S.1
Thompson, S.G.2
-
31
-
-
67649851008
-
Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia
-
Sanna S, Busonero F, Maschio A, et al. Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia. Hum Mol Genet 2009;18: 2711-2718
-
(2009)
Hum Mol Genet
, vol.18
, pp. 2711-2718
-
-
Sanna, S.1
Busonero, F.2
Maschio, A.3
-
32
-
-
33751162094
-
Impact of diabetes mellitus on the relationships between iron-, inflammatory-and oxidative stress status
-
Van Campenhout A, Van Campenhout C, Lagrou AR, et al. Impact of diabetes mellitus on the relationships between iron-, inflammatory-and oxidative stress status. Diabetes Metab Res Rev 2006;22: 444-454
-
(2006)
Diabetes Metab Res Rev
, vol.22
, pp. 444-454
-
-
Van Campenhout, A.1
Van Campenhout, C.2
Lagrou, A.R.3
-
33
-
-
33745234081
-
Diabetes, glucose toxicity, and oxidative stress: A case of double jeopardy for the pancreatic islet beta cell
-
Robertson RP, Harmon JS. Diabetes, glucose toxicity, and oxidative stress: A case of double jeopardy for the pancreatic islet beta cell. Free Radic Biol Med 2006;41: 177-184
-
(2006)
Free Radic Biol Med
, vol.41
, pp. 177-184
-
-
Robertson, R.P.1
Harmon, J.S.2
-
34
-
-
84870242831
-
Bilirubin, the gold within
-
Seppen J, Bosma P. Bilirubin, the gold within. Circulation 2012;126: 2547-2549
-
(2012)
Circulation
, vol.126
, pp. 2547-2549
-
-
Seppen, J.1
Bosma, P.2
-
35
-
-
18244370762
-
Inflammation, stress, and diabetes
-
Wellen KE, Hotamisligil GS. Inflammation, stress, and diabetes. J Clin Invest 2005;115: 1111-1119
-
(2005)
J Clin Invest
, vol.115
, pp. 1111-1119
-
-
Wellen, K.E.1
Hotamisligil, G.S.2
-
36
-
-
53849129224
-
The sensitivity of pancreatic beta-cells to mitochondrial injuries triggered by lipotoxicity and oxidative stress
-
Li N, Frigerio F, Maechler P. The sensitivity of pancreatic beta-cells to mitochondrial injuries triggered by lipotoxicity and oxidative stress. Biochem Soc Trans 2008;36: 930-934
-
(2008)
Biochem Soc Trans
, vol.36
, pp. 930-934
-
-
Li, N.1
Frigerio, F.2
Maechler, P.3
-
37
-
-
84874434356
-
Role of advanced glycation end products (AGE) and soluble receptor for AGE (sRAGE) in vascular complications in diabetes
-
Yamagishi S. [Role of advanced glycation end products (AGE) and soluble receptor for AGE (sRAGE) in vascular complications in diabetes]. Nihon Rinsho 2012;70(Suppl. 5): 243-247
-
(2012)
Nihon Rinsho
, vol.70
, pp. 243-247
-
-
Yamagishi, S.1
-
38
-
-
0032913309
-
Role of oxidative stress in diabetic complications: A new perspective on an old paradigm
-
Baynes JW, Thorpe SR. Role of oxidative stress in diabetic complications: A new perspective on an old paradigm. Diabetes 1999;48: 1-9
-
(1999)
Diabetes
, vol.48
, pp. 1-9
-
-
Baynes, J.W.1
Thorpe, S.R.2
-
39
-
-
0034626735
-
Oxidants, oxidative stress and the biology of ageing
-
Finkel T, Holbrook NJ. Oxidants, oxidative stress and the biology of ageing. Nature 2000;408: 239-247
-
(2000)
Nature
, vol.408
, pp. 239-247
-
-
Finkel, T.1
Holbrook, N.J.2
-
40
-
-
84865984236
-
The role of bilirubin in diabetes, metabolic syndrome, and cardiovascular diseases
-
Vítek L. The role of bilirubin in diabetes, metabolic syndrome, and cardiovascular diseases. Front Pharmacol 2012;3: 55
-
(2012)
Front Pharmacol
, vol.3
, pp. 55
-
-
Vítek, L.1
-
41
-
-
84905044209
-
Bilirubin and progression of nephropathy in type 2 diabetes: A post hoc analysis of RENAAL with independent replication in IDNT
-
Riphagen IJ, Deetman PE, Bakker SJ, et al. Bilirubin and progression of nephropathy in type 2 diabetes: A post hoc analysis of RENAAL with independent replication in IDNT. Diabetes 2014;63: 2845-2853
-
(2014)
Diabetes
, vol.63
, pp. 2845-2853
-
-
Riphagen, I.J.1
Deetman, P.E.2
Bakker, S.J.3
-
42
-
-
78650056520
-
Hyperbilirubinemia reduces the streptozotocininduced pancreatic damage through attenuating the oxidative stress in the Gunn rat
-
Fu YY, Kang KJ, Ahn JM, et al. Hyperbilirubinemia reduces the streptozotocininduced pancreatic damage through attenuating the oxidative stress in the Gunn rat. Tohoku J Exp Med 2010;222: 265-273
-
(2010)
Tohoku J Exp Med
, vol.222
, pp. 265-273
-
-
Fu, Y.Y.1
Kang, K.J.2
Ahn, J.M.3
-
43
-
-
84896870948
-
Bilirubin increases insulin sensitivity in leptin-receptor deficient and diet-induced obese mice through suppression of ER stress and chronic inflammation
-
Dong H, Huang H, Yun X, et al. Bilirubin increases insulin sensitivity in leptin-receptor deficient and diet-induced obese mice through suppression of ER stress and chronic inflammation. Endocrinology 2014;155: 818-828
-
(2014)
Endocrinology
, vol.155
, pp. 818-828
-
-
Dong, H.1
Huang, H.2
Yun, X.3
-
44
-
-
84890130280
-
Higher serum bilirubin level as a protective factor for the development of diabetes in healthy Korean men: A 4 year retrospective longitudinal study
-
Jung CH, Lee MJ, Kang YM, et al. Higher serum bilirubin level as a protective factor for the development of diabetes in healthy Korean men: A 4 year retrospective longitudinal study. Metabolism 2014;63: 87-93
-
(2014)
Metabolism
, vol.63
, pp. 87-93
-
-
Jung, C.H.1
Lee, M.J.2
Kang, Y.M.3
-
45
-
-
84901207763
-
Inherited disorders of bilirubin transport and conjugation: New insights into molecular mechanisms and consequences
-
Erlinger S, Arias IM, Dhumeaux D. Inherited disorders of bilirubin transport and conjugation: New insights into molecular mechanisms and consequences. Gastroenterology 2014;146: 1625-1638
-
(2014)
Gastroenterology
, vol.146
, pp. 1625-1638
-
-
Erlinger, S.1
Arias, I.M.2
Dhumeaux, D.3
-
47
-
-
70349235444
-
Sex hormone-binding globulin and risk of type 2 diabetes in women and men
-
Ding EL, Song Y, Manson JE, et al. Sex hormone-binding globulin and risk of type 2 diabetes in women and men. N Engl J Med 2009;361: 1152-1163
-
(2009)
N Engl J Med
, vol.361
, pp. 1152-1163
-
-
Ding, E.L.1
Song, Y.2
Manson, J.E.3
-
48
-
-
79961185600
-
Power and instrument strength requirements for Mendelian randomization studies using multiple genetic variants
-
Pierce BL, Ahsan H, Vanderweele TJ. Power and instrument strength requirements for Mendelian randomization studies using multiple genetic variants. Int J Epidemiol 2011;40: 740-752
-
(2011)
Int J Epidemiol
, vol.40
, pp. 740-752
-
-
Pierce, B.L.1
Ahsan, H.2
Vanderweele, T.J.3
-
49
-
-
84864473444
-
Hyperbilirubinemia, augmentation of endothelial function, and decrease in oxidative stress in Gilbert syndrome
-
Maruhashi T, Soga J, Fujimura N, et al. Hyperbilirubinemia, augmentation of endothelial function, and decrease in oxidative stress in Gilbert syndrome. Circulation 2012;126: 598-603
-
(2012)
Circulation
, vol.126
, pp. 598-603
-
-
Maruhashi, T.1
Soga, J.2
Fujimura, N.3
-
50
-
-
80055060938
-
Mendelian randomization study of B-type natriuretic peptide and type 2 diabetes: Evidence of causal association from population studies
-
Pfister R, Sharp S, Luben R, et al. Mendelian randomization study of B-type natriuretic peptide and type 2 diabetes: Evidence of causal association from population studies. PLoS Med 2011;8: E1001112
-
(2011)
PLoS Med
, vol.8
, pp. e1001112
-
-
Pfister, R.1
Sharp, S.2
Luben, R.3
|